Compound ID |
Compound Name |
Compound Formula |
CP0254388
|
5-Methoxy-9-oxo-9,10-dihydro-acridine-4-carboxylic acid {4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-amide
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|
C34H33N3O5
|
1
|
1 |
IC50 = 193 nM
|
|
|
CP0116921
|
1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolinyl)ethyl]phenyl}-4,5-dimethoxy-2-(3-quinolylcarboxamido)benzamide
Show/Hide
|
C38H38N4O6
|
2
|
1 |
IC50 = 223 nM
|
|
|
2 |
IC50 = 356 nM
|
|
|
CP0417560
|
methyl 4-[4-[[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]methyl]phenyl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C42H45N3O8
|
1
|
1 |
IC50 = 1230 nM
|
|
|
CP0531226
|
N-[5-[1-(2-morpholin-4-ylethyl)triazol-4-yl]-2-propanoylphenyl]-4-oxochromene-2-carboxamide
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|
C27H27N5O5
|
1
|
1 |
IC50 = 1342 nM
|
|
|
CP0542883
|
methyl 4-[1-[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]triazol-4-yl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C45H48N6O8
|
1
|
1 |
IC50 = 1623 nM
|
|
|
CP0455202
|
methyl 4-[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)phenyl]-2-(quinoline-6-carbonylamino)benzoate
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|
C34H29N3O3
|
1
|
1 |
IC50 = 4490 nM
|
|
|
CP0469410
|
methyl 4-[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C43H47N3O8
|
1
|
1 |
IC50 = 5420 nM
|
|
|
CP0455199
|
methyl 4-[4-[2-[6,7-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C49H59N3O11
|
1
|
1 |
IC50 = 5990 nM
|
|
|
CP0386291
|
5-[(4-bromophenyl)methoxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxochromene-2-carboxamide
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|
C28H23BrN2O5
|
1
|
1 |
IC50 = 6756 nM
|
|
|
CP0462999
|
N-(3-morpholin-4-ylpropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
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|
C26H27N5O2
|
1
|
1 |
IC50 = 6800 nM
|
|
|
CP0373409
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(quinoline-3-carbonylamino)benzoate
Show/Hide
|
C38H36N4O6
|
1
|
1 |
IC50 = 9450 nM
|
|
|
CP0394488
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(quinoline-6-carbonylamino)benzoate
Show/Hide
|
C38H36N4O6
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0542882
|
methyl 4-[1-[4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]triazol-4-yl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C38H34N6O5
|
1
|
1 |
IC50 >= 10730 nM
|
|
|
CP0455200
|
methyl 4-[4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]-2-(quinoline-6-carbonylamino)benzoate
Show/Hide
|
C36H33N3O5
|
1
|
1 |
IC50 = 10900 nM
|
|
|
CP0415114
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C38H36N4O6
|
2
|
1 |
IC50 >= 12080 nM
|
|
|
2 |
IC50 > 29000 nM
|
|
|
CP0423799
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(pyridine-3-carbonylamino)benzoate
Show/Hide
|
C34H34N4O6
|
1
|
1 |
IC50 > 14000 nM
|
|
|
CP0394487
|
N-[3-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-5-methoxyphenyl]quinoline-3-carboxamide
Show/Hide
|
C37H36N4O5
|
1
|
1 |
IC50 > 15000 nM
|
|
|
CP0462357
|
N-[5-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-methylphenyl]quinoline-3-carboxamide
Show/Hide
|
C37H36N4O4
|
1
|
1 |
IC50 > 15000 nM
|
|
|
CP0398446
|
2-(4-benzylpiperazine-1-carbonyl)-5-phenylmethoxychromen-4-one
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|
C28H26N2O4
|
1
|
1 |
IC50 = 15800 nM
|
|
|
CP0502250
|
N-[5-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2,3-dimethoxyphenyl]quinoline-3-carboxamide
Show/Hide
|
C38H38N4O6
|
1
|
1 |
IC50 > 17000 nM
|
|
|
CP0417519
|
methyl 4-[4-[[7-methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]methyl]phenyl]-2-(quinoline-6-carbonylamino)benzoate
Show/Hide
|
C42H45N3O8
|
1
|
1 |
IC50 = 18000 nM
|
|
|
CP0531223
|
N-[5-[1-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-propanoylphenyl]-6-oxo-1H-pyridine-2-carboxamide
Show/Hide
|
C36H36N6O5
|
1
|
1 |
IC50 > 18450 nM
|
|
|
CP0462358
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(pyrazine-2-carbonylamino)benzoate
Show/Hide
|
C33H33N5O6
|
1
|
1 |
IC50 > 20000 nM
|
|
|
CP0490349
|
N-[5-[1-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-(2-methylpropanoyl)phenyl]quinoline-2-carboxamide
Show/Hide
|
C41H40N6O4
|
1
|
1 |
IC50 >= 21830 nM
|
|
|
CP0488947
|
methyl 4-[1-[4-[[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]methyl]phenyl]triazol-4-yl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C44H46N6O8
|
1
|
1 |
IC50 >= 25030 nM
|
|
|
CP0141589
|
3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester
Show/Hide
|
C26H35N3O5
|
1
|
1 |
IC50 >= 25520 nM
|
|
|
CP0508791
|
5,7-dimethoxy-2-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]chromen-4-one
Show/Hide
|
C23H23F3N2O4
|
1
|
1 |
IC50 = 31300 nM
|
|
|
CP0474629
|
5,7-dimethoxy-2-[4-[(3-nitrophenyl)methyl]piperazin-1-yl]chromen-4-one
Show/Hide
|
C22H23N3O6
|
1
|
1 |
IC50 = 32800 nM
|
|
|
CP0433316
|
5,7-dimethoxy-2-[4-[2-(4-nitrophenyl)ethyl]piperazin-1-yl]chromen-4-one
Show/Hide
|
C23H25N3O6
|
1
|
1 |
IC50 = 33000 nM
|
|
|
CP0382010
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-(quinoxaline-2-carbonylamino)benzoate
Show/Hide
|
C37H35N5O6
|
1
|
1 |
IC50 > 34000 nM
|
|
|
CP0483165
|
5,7-dimethoxy-2-[4-[[4-(trifluoromethylsulfanyl)phenyl]methyl]piperazin-1-yl]chromen-4-one
Show/Hide
|
C23H23F3N2O4S
|
1
|
1 |
IC50 = 36600 nM
|
|
|
CP0488948
|
methyl 4-[1-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C37H32N6O3
|
1
|
1 |
IC50 >= 38270 nM
|
|
|
CP0490350
|
N-[5-[1-[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]triazol-4-yl]-2-propanoylphenyl]quinoline-2-carboxamide
Show/Hide
|
C46H50N6O7
|
1
|
1 |
IC50 >= 44460 nM
|
|
|
CP0373171
|
methyl 4-[[4-[2-[7-methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C44H48N4O9
|
1
|
1 |
IC50 > 50000 nM
|
|
|
CP0437995
|
methyl 4-[[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-2-carbonylamino)benzoate
Show/Hide
|
C44H48N4O9
|
1
|
1 |
IC50 > 50000 nM
|
|
|
CP0465345
|
methyl 4-[[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-6-carbonylamino)benzoate
Show/Hide
|
C44H48N4O9
|
1
|
1 |
IC50 > 50000 nM
|
|
|
CP0898202
|
N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-2-carbonyl)-amino]-terephthalamic acid trifluoroacetic acid
Show/Hide
|
C39H35F3N4O8
|
1
|
1 |
IC50 > 50000 nM
|
|
|
CP0904106
|
N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-6-carbonyl)-amino]-terephthalamic acid trifluoroacetic acid
Show/Hide
|
C45H47F3N4O11
|
1
|
1 |
IC50 > 50000 nM
|
|
|
CP0904107
|
N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-6-carbonyl)-amino]-terephthalamic acid trifluoroacetic acid
Show/Hide
|
C45H47F3N4O11
|
1
|
1 |
IC50 > 50000 nM
|
|
|
CP0459693
|
methyl 4-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-[(5-methylpyrazine-2-carbonyl)amino]benzoate
Show/Hide
|
C34H35N5O6
|
1
|
1 |
IC50 > 57000 nM
|
|
|
CP0434377
|
5,7-dimethoxy-2-[4-[(4-nitrophenyl)methyl]piperazine-1-carbonyl]chromen-4-one
Show/Hide
|
C23H23N3O7
|
1
|
1 |
IC50 = 58200 nM
|
|
|
CP0390463
|
2-[4-[(3,4-difluorophenyl)methyl]piperazin-1-yl]-5,7-dimethoxychromen-4-one
Show/Hide
|
C22H22F2N2O4
|
1
|
1 |
IC50 = 58500 nM
|
|
|
CP0530501
|
(Z)-2-(3,4-dimethoxyphenyl)-3-[5-(4-hydroxypiperidin-1-yl)thiophen-2-yl]prop-2-enenitrile
Show/Hide
|
C20H22N2O3S
|
1
|
1 |
IC50 >= 65480 nM
|
|
|
CP0406173
|
5,7-dimethoxy-2-[4-[2-(4-nitrophenyl)ethyl]piperazine-1-carbonyl]chromen-4-one
Show/Hide
|
C24H25N3O7
|
1
|
1 |
IC50 = 83900 nM
|
|
|
CP0437996
|
methyl 4-[[4-[2-[7-methoxy-6-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]phenyl]carbamoyl]-2-(quinoline-6-carbonylamino)benzoate
Show/Hide
|
C44H48N4O9
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0878929
|
N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-2-carbonyl)-amino]-terephthalamic acid trifluoroacetic acid
Show/Hide
|
C45H47F3N4O11
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0898201
|
N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-2-carbonyl)-amino]-terephthalamic acid trifluoroacetic acid
Show/Hide
|
C45H47F3N4O11
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0390465
|
methyl 4-[[4-(5,7-dimethoxy-4-oxochromen-2-yl)piperazin-1-yl]methyl]benzoate
Show/Hide
|
C24H26N2O6
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0406172
|
5,7-dimethoxy-2-[4-[(2-nitrophenyl)methyl]piperazin-1-yl]chromen-4-one
Show/Hide
|
C22H23N3O6
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0462997
|
5,7-dimethoxy-2-[4-[[4-(trifluoromethylsulfonyl)phenyl]methyl]piperazin-1-yl]chromen-4-one
Show/Hide
|
C23H23F3N2O6S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0497740
|
4-[[4-(5,7-dimethoxy-4-oxochromen-2-yl)piperazin-1-yl]methyl]benzonitrile
Show/Hide
|
C23H23N3O4
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0906528
|
N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2-[(quinoline-6-carbonyl)-amino]-terephthalamic acid trifluoroacetic acid
Show/Hide
|
C39H35F3N4O8
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0486097
|
N-[5-methyl-2-[1-(2-morpholin-4-ylethyl)triazol-4-yl]phenyl]-4-oxochromene-2-carboxamide
Show/Hide
|
C25H25N5O4
|
1
|
1 |
IC50 > 1601 nM
|
|
|
CP0486096
|
N-[5-[1-(2-hydroxyethyl)triazol-4-yl]-2-propanoylphenyl]-4-oxochromene-2-carboxamide
Show/Hide
|
C23H20N4O5
|
1
|
1 |
IC50 > 2285 nM
|
|
|
CP0563376
|
N-[5-[1-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-propanoylphenyl]-5-methoxypyridine-2-carboxamide
Show/Hide
|
C37H38N6O5
|
1
|
1 |
IC50 > 2775 nM
|
|
|
CP0382011
|
N-[5-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-2-methoxyphenyl]quinoline-3-carboxamide
Show/Hide
|
C37H36N4O5
|
1
|
1 |
IC50 > 6000 nM
|
|
|
CP0531227
|
N-[5-[1-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]triazol-4-yl]-2-propanoylphenyl]-6-methylpyridine-2-carboxamide
Show/Hide
|
C37H38N6O4
|
1
|
1 |
IC50 > 9972 nM
|
|
|