| Compound ID |
Compound Name |
Compound Formula |
|
CP0526754
|
GS-5806
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|
C24H30ClN7O3S
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0437310
|
(2S)-19-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7,16-trimethyl-11-oxa-3,16,20,22,23-pentazatetracyclo[19.2.1.05,10.017,22]tetracosa-1(23),5(10),6,8,17,19,21(24)-heptaen-4-one
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|
C27H37N7O2
|
1
|
| 1 |
EC50 = 0.66 nM
|
|
|
|
CP0534543
|
propan-2-yl 1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-2'-oxospiro[azetidine-3,3'-indole]-1-carboxylate
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|
C26H29BrN4O4
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0552508
|
4-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-1,1,1-trifluorobutan-2-ol
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|
C19H17ClF3N5O3S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0541273
|
N'-[2-(1,1-dioxo-3,5-dihydro-2H-1lambda6,4-benzothiazepin-4-yl)-6-methylquinolin-4-yl]propane-1,3-diamine
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|
C22H26N4O2S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0420336
|
(2S)-19-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7,18-trimethyl-11-oxa-3,16,20,22,23-pentazatetracyclo[19.2.1.05,10.017,22]tetracosa-1(23),5(10),6,8,17,19,21(24)-heptaen-4-one
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|
C27H37N7O2
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0411864
|
1'-[[7-chloro-3-(3-methylsulfonylpropyl)imidazo[1,2-a]pyridin-2-yl]methyl]spiro[cyclopropane-1,3'-pyrrolo[2,3-c]pyridine]-2'-one
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|
C21H21ClN4O3S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0396334
|
N-[(3-aminooxetan-3-yl)methyl]-2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-amine
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|
C24H27FN4O
|
3
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
IC50 = 2560 nM
|
|
|
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CP0557671
|
(2S)-23-[(3S)-3-aminopyrrolidin-1-yl]-11,20-dimethyl-15-oxa-7,20,24,26,27-pentazapentacyclo[23.2.1.02,7.09,14.021,26]octacosa-1(27),9(14),10,12,21,23,25(28)-heptaen-8-one
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|
C28H37N7O2
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0519630
|
1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
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|
C22H22BrN3O2
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0389296
|
3-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]propan-1-ol
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|
C18H18ClN5O3S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0478152
|
4-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-1,1-difluorobutan-2-ol
Show/Hide
|
C19H18ClF2N5O3S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0472926
|
1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1-(2-methylpropanoyl)spiro[azetidine-3,3'-indole]-2'-one
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|
C26H29BrN4O3
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0536963
|
1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1-methylsulfonylspiro[azetidine-3,3'-indole]-2'-one
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|
C23H25BrN4O4S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0493235
|
1-[[5-chloro-1-(5,5,5-trifluoropentyl)benzimidazol-2-yl]methyl]-3-methylsulfonylpyrazolo[3,4-c]pyridine
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|
C20H19ClF3N5O2S
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0414427
|
N-[(1S)-1-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]propyl]-2-methoxy-N,5-dimethylbenzamide
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|
C24H32N6O2
|
1
|
| 1 |
EC50 = 3.8 nM
|
|
|
|
CP0411830
|
4-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]butan-1-ol
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|
C19H20ClN5O3S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0476904
|
N'-[2-(1,1-dioxo-3,5-dihydro-2H-1lambda6,4-benzothiazepin-4-yl)-6-methylquinolin-4-yl]ethane-1,2-diamine
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|
C21H24N4O2S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0493234
|
1-[[5-chloro-1-(3,3,3-trifluoropropyl)benzimidazol-2-yl]methyl]-3-methylsulfonylpyrazolo[3,4-c]pyridine
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|
C18H15ClF3N5O2S
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0389295
|
1-[[5-chloro-1-(3-methylsulfonylpropyl)benzimidazol-2-yl]methyl]-3-methylsulfonylpyrazolo[3,4-c]pyridine
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|
C19H20ClN5O4S2
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0561839
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[indole-3,3'-thietane]-2-one
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|
C22H22BrN3O2S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0396333
|
N-[3-(aminomethyl)oxetan-3-yl]-2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-amine
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|
C24H27FN4O
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0072620
|
1-[[5-chloro-1-(oxetan-3-ylmethyl)benzimidazol-2-yl]methyl]-3-methylsulfonylpyrazolo[3,4-c]pyridine
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|
C19H18ClN5O3S
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0561838
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[indole-3,4'-oxane]-2-one
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|
C24H26BrN3O3
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0409299
|
(2S)-20-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7,17-trimethyl-11-oxa-3,17,21,23,24-pentazatetracyclo[20.2.1.05,10.018,23]pentacosa-1(24),5(10),6,8,18,20,22(25)-heptaen-4-one
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|
C28H39N7O2
|
1
|
| 1 |
EC50 = 6.2 nM
|
|
|
|
CP0552510
|
5-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-2-methylpentan-2-ol
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|
C21H24ClN5O3S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0567404
|
1'-[[5-(aminomethyl)-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
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|
C23H26N4O2
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0539791
|
N'-[2-(1,1-dioxo-3,5-dihydro-2H-1lambda6,4-benzothiazepin-4-yl)-6-methylquinolin-4-yl]butane-1,4-diamine
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0478151
|
4-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-2-methylbutan-2-ol
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|
C20H22ClN5O3S
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
|
CP0472923
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[indole-3,3'-oxolane]-2-one
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|
C23H24BrN3O3
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
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CP0534542
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1'-methylsulfonylspiro[indole-3,3'-pyrrolidine]-2-one
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|
C24H27BrN4O4S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0531760
|
(2S)-19-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7,16,18-tetramethyl-11-oxa-3,16,20,22,23-pentazatetracyclo[19.2.1.05,10.017,22]tetracosa-1(23),5(10),6,8,17,19,21(24)-heptaen-4-one
Show/Hide
|
C28H39N7O2
|
1
|
| 1 |
EC50 = 8.1 nM
|
|
|
|
CP0411862
|
1-[[5-chloro-1-(3-methylsulfonylpropyl)benzimidazol-2-yl]methyl]-N,N-dimethylindole-3-sulfonamide
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|
C22H25ClN4O4S2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0515513
|
1'-[[5-chloro-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
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|
C22H22ClN3O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0536881
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1'-(2-methylpropanoyl)spiro[indole-3,3'-pyrrolidine]-2-one
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|
C27H31BrN4O3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0408528
|
2-N-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]propane-1,2-diamine
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|
C23H27FN4
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
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CP0472925
|
propan-2-yl 1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-2-oxospiro[indole-3,3'-pyrrolidine]-1'-carboxylate
Show/Hide
|
C27H31BrN4O4
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
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CP0429415
|
N'-[2-(1,1-dioxo-3,5-dihydro-2H-1lambda6,4-benzothiazepin-4-yl)quinolin-4-yl]ethane-1,2-diamine
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|
C20H22N4O2S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
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CP0536091
|
5-chloro-2-[(3-methylsulfonylindazol-1-yl)methyl]-1-(3-methylsulfonylpropyl)benzimidazole
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|
C20H21ClN4O4S2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
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CP0536100
|
2-[2-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]ethoxy]ethanol
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|
C19H20ClN5O4S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
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CP0558759
|
1-N-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]-2-methylpropane-1,2-diamine
Show/Hide
|
C24H29FN4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
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CP0567403
|
1'-[[5-fluoro-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
Show/Hide
|
C22H22FN3O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
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CP0539792
|
1-N-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]propane-1,2-diamine
Show/Hide
|
C23H27FN4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0569239
|
N'-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]-N-methylethane-1,2-diamine
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|
C23H27FN4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0567400
|
1'-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
Show/Hide
|
C22H23N3O2
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
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CP0534541
|
1'-[[1-(4-hydroxybutyl)-5-methylbenzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
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CP0574801
|
1'-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-pyrrolo[2,3-c]pyridine]-2'-one
Show/Hide
|
C21H22N4O2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0574962
|
1'-[[7-chloro-3-(2-methylsulfonylethyl)imidazo[1,2-a]pyridin-2-yl]methyl]spiro[cyclopropane-1,3'-pyrrolo[2,3-c]pyridine]-2'-one
Show/Hide
|
C20H19ClN4O3S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0437313
|
(2S)-18-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7,15-trimethyl-11-oxa-3,15,19,21,22-pentazatetracyclo[18.2.1.05,10.016,21]tricosa-1(22),5(10),6,8,16,18,20(23)-heptaen-4-one
Show/Hide
|
C26H35N7O2
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
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CP0536964
|
1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[azetidine-3,3'-indole]-2'-one
Show/Hide
|
C22H23BrN4O2
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0036151
|
BMS-433771
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|
C21H23N5O2
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
EC50 = 28 nM
|
|
|
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CP0472924
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1',1'-dioxospiro[indole-3,3'-thietane]-2-one
Show/Hide
|
C22H22BrN3O4S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0532108
|
1'-[[1-(4-hydroxybutyl)-5-iodobenzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
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|
C22H22IN3O2
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0550380
|
2-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]ethanol
Show/Hide
|
C17H16ClN5O3S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
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CP0569240
|
2-N-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]-2-methylpropane-1,2-diamine
Show/Hide
|
C24H29FN4
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0558761
|
2-[[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]amino]acetamide
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|
C22H23FN4O
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
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CP0565118
|
N'-[2-(1,1-dioxo-3,5-dihydro-2H-1lambda6,4-benzothiazepin-4-yl)-6-methylquinolin-4-yl]pentane-1,5-diamine
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
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CP0486179
|
N'-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]-N-(oxetan-3-yl)ethane-1,2-diamine
Show/Hide
|
C25H29FN4O
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
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CP0464958
|
3-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-2,2-difluoropropan-1-ol
Show/Hide
|
C18H16ClF2N5O3S
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
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CP0472919
|
6'-fluoro-1'-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
Show/Hide
|
C22H22FN3O2
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
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CP0429420
|
N-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]-N',N'-dimethylethane-1,2-diamine
Show/Hide
|
C24H29FN4
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
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CP0539790
|
2-amino-N-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]acetamide
Show/Hide
|
C22H23FN4O
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
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CP0486178
|
2-[[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]amino]ethanol
Show/Hide
|
C22H24FN3O
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
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CP0427480
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1'-(oxetan-3-yl)spiro[indole-3,4'-piperidine]-2-one
Show/Hide
|
C27H31BrN4O3
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
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CP0532109
|
1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1-methylspiro[azetidine-3,3'-indole]-2'-one
Show/Hide
|
C23H25BrN4O2
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
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CP0469722
|
5-chloro-2-[(3-methylsulfonylindol-1-yl)methyl]-1-(3-methylsulfonylpropyl)benzimidazole
Show/Hide
|
C21H22ClN3O4S2
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
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CP0411863
|
5-chloro-2-[(3-ethylsulfonylindol-1-yl)methyl]-1-(3-methylsulfonylpropyl)benzimidazole
Show/Hide
|
C22H24ClN3O4S2
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
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CP0437312
|
(2S)-21-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7,18-trimethyl-11-oxa-3,18,22,24,25-pentazatetracyclo[21.2.1.05,10.019,24]hexacosa-1(25),5(10),6,8,19,21,23(26)-heptaen-4-one
Show/Hide
|
C29H41N7O2
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
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CP0567406
|
1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-4'-methylspiro[indole-3,2'-morpholine]-2-one
Show/Hide
|
C24H27BrN4O3
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
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CP0526753
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(2S)-19-[(3S)-3-aminopyrrolidin-1-yl]-2-ethyl-3,7-dimethyl-11-oxa-3,16,20,22,23-pentazatetracyclo[19.2.1.05,10.017,22]tetracosa-1(23),5(10),6,8,17,19,21(24)-heptaen-4-one
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C26H35N7O2
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1
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| 1 |
EC50 = 61 nM
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CP0393308
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N'-[2-(5,5-difluoro-3,4-dihydro-1H-2-benzazepin-2-yl)-6-methylquinolin-4-yl]ethane-1,2-diamine
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C22H24F2N4
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1
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| 1 |
EC50 = 62 nM
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CP0486177
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2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methyl-N-(piperidin-2-ylmethyl)quinolin-4-amine
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C26H31FN4
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1
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| 1 |
EC50 = 71 nM
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CP0429418
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N'-[6-methyl-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
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C22H26N4
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1
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| 1 |
EC50 = 73 nM
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CP0547904
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3-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-2,2-difluoropropan-1-amine
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C18H17ClF2N6O2S
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1
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| 1 |
EC50 = 75 nM
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CP0567408
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1'-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[imidazolidine-5,3'-indole]-2,2',4-trione
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C22H20BrN5O4
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1
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| 1 |
EC50 = 76 nM
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CP0549826
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5-chloro-1-(3-methylsulfonylpropyl)-2-[(3-methylsulfonylpyrrolo[2,3-c]pyridin-1-yl)methyl]benzimidazole
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C20H21ClN4O4S2
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1
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| 1 |
EC50 = 78 nM
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CP0486401
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1-[[5-chloro-1-[2-(2-methoxyethoxy)ethyl]benzimidazol-2-yl]methyl]-3-methylsulfonylpyrazolo[3,4-c]pyridine
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C20H22ClN5O4S
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1
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| 1 |
EC50 = 88 nM
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CP0547872
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5-chloro-1-(2-methylsulfonylethyl)-2-[(3-methylsulfonylindol-1-yl)methyl]benzimidazole
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C20H20ClN3O4S2
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1
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| 1 |
EC50 = 93 nM
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CP0478150
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5-chloro-1-(3-methylsulfonylpropyl)-2-[(3-propan-2-ylsulfonylindol-1-yl)methyl]benzimidazole
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C23H26ClN3O4S2
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1
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| 1 |
EC50 = 100 nM
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CP0558758
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N'-[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]ethane-1,2-diamine
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C22H25FN4
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1
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| 1 |
EC50 = 100 nM
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CP0538739
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1-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-4-methylquinolin-2-one
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C22H23N3O2
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1
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| 1 |
EC50 = 110 nM
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CP0561834
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1-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-4-methylquinazolin-2-one
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C21H22N4O2
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1
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| 1 |
EC50 = 110 nM
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CP0429417
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N'-[6-chloro-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C21H23ClN4
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1
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| 1 |
EC50 = 120 nM
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CP0567401
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1-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-3,3-dimethylindol-2-one
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C22H25N3O2
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1
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| 1 |
EC50 = 130 nM
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CP0547866
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5-chloro-2-[(3-cyclopropylsulfonylindol-1-yl)methyl]-1-(3-methylsulfonylpropyl)benzimidazole
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C23H24ClN3O4S2
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1
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| 1 |
EC50 = 140 nM
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CP0558760
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2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methyl-N-(2-piperazin-1-ylethyl)quinolin-4-amine
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C26H32FN5
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1
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| 1 |
EC50 = 150 nM
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CP0411829
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5-chloro-2-[(5-fluoro-3-methylsulfonylindol-1-yl)methyl]-1-(3-methylsulfonylpropyl)benzimidazole
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C21H21ClFN3O4S2
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1
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| 1 |
EC50 = 180 nM
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CP0534539
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4-[2-[(3-methylindazol-1-yl)methyl]benzimidazol-1-yl]butan-1-ol
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C20H22N4O
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1
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| 1 |
EC50 = 180 nM
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CP0561836
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1-(4-hydroxybutyl)-2-[(2'-oxospiro[cyclopropane-1,3'-indole]-1'-yl)methyl]benzimidazole-5-carbonitrile
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C23H22N4O2
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1
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| 1 |
EC50 = 190 nM
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CP0559032
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1-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]indole-3-carbonitrile
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C21H20N4O
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1
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| 1 |
EC50 = 200 nM
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CP0429375
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N'-[2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
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C21H24N4
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2
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| 1 |
EC50 = 200 nM
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| 2 |
IC50 = 2300 nM
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CP0561837
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1'-[[1-(4-hydroxybutyl)-5-(trifluoromethyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
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C23H22F3N3O2
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1
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| 1 |
EC50 = 210 nM
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CP0393310
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1-amino-3-[[2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]amino]propan-2-ol
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C22H26N4O
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1
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| 1 |
EC50 = 220 nM
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CP0396351
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1-amino-3-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]amino]propan-2-ol
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C21H24N4O
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1
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| 1 |
EC50 = 220 nM
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CP0464959
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3-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-1,1,1-trifluoropropan-2-amine
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C18H16ClF3N6O2S
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1
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| 1 |
EC50 = 221 nM
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CP0429419
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N'-[6-methyl-2-(1,2,3,5-tetrahydro-1,4-benzodiazepin-4-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C21H25N5
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1
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| 1 |
EC50 = 230 nM
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CP0558753
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N'-[2-(3,5-dihydro-2H-1,4-benzoxazepin-4-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C20H22N4O
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1
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| 1 |
EC50 = 230 nM
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CP0563173
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2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methyl-N-(2-piperidin-1-ylethyl)quinolin-4-amine
Show/Hide
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C27H33FN4
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1
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| 1 |
EC50 = 280 nM
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CP0478149
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1-[[5-chloro-1-(3-methylsulfonylpropyl)benzimidazol-2-yl]methyl]-N-methylindole-3-sulfonamide
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C21H23ClN4O4S2
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1
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| 1 |
EC50 = 290 nM
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CP0561840
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1-[[5-bromo-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1'-methylspiro[indole-3,4'-piperidine]-2-one
Show/Hide
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C25H29BrN4O2
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1
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| 1 |
EC50 = 307 nM
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CP0412124
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4-[4-(2-aminoethylamino)-6-methylquinolin-2-yl]-3,5-dihydro-1H-1,4-benzodiazepin-2-one
Show/Hide
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C21H23N5O
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1
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| 1 |
EC50 = 310 nM
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CP0541319
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N'-[6-methoxy-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C22H26N4O
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1
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| 1 |
EC50 = 320 nM
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CP0472920
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3-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1,3-benzoxazol-2-one
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C19H19N3O3
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1
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| 1 |
EC50 = 350 nM
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CP0408526
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N'-[2-(7-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C22H25FN4
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1
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| 1 |
EC50 = 460 nM
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CP0534540
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4-[2-[[2-(1,3-thiazol-4-yl)benzimidazol-1-yl]methyl]benzimidazol-1-yl]butan-1-ol
Show/Hide
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C22H21N5OS
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1
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| 1 |
EC50 = 470 nM
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CP0567402
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5-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-2-methyl-2,3-dihydro-1H-1,5-benzodiazepin-4-one
Show/Hide
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C22H26N4O2
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1
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| 1 |
EC50 = 480 nM
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CP0408529
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2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methyl-N-(2-morpholin-4-ylethyl)quinolin-4-amine
Show/Hide
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C26H31FN4O
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1
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| 1 |
EC50 = 540 nM
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CP0515512
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4-[2-(pyrrolo[2,3-c]pyridin-1-ylmethyl)benzimidazol-1-yl]butan-1-ol
Show/Hide
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C19H20N4O
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1
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| 1 |
EC50 = 1000 nM
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CP0552509
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3-[5-chloro-2-[(3-methylsulfonylpyrazolo[3,4-c]pyridin-1-yl)methyl]benzimidazol-1-yl]-2,2-dimethylpropan-1-ol
Show/Hide
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C20H22ClN5O3S
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1
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| 1 |
EC50 = 1070 nM
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CP0558755
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N'-[8-chloro-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C21H23ClN4
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1
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| 1 |
EC50 = 1100 nM
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CP0558757
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N'-[2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-(trifluoromethyl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C22H23F3N4
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1
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| 1 |
EC50 = 1100 nM
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CP0412122
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N'-[6-fluoro-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C21H23FN4
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1
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| 1 |
EC50 = 1500 nM
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CP0561833
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4-[2-[[2-(trifluoromethyl)benzimidazol-1-yl]methyl]benzimidazol-1-yl]butan-1-ol
Show/Hide
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C20H19F3N4O
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1
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| 1 |
EC50 = 1700 nM
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CP0536961
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4-[2-(indazol-1-ylmethyl)benzimidazol-1-yl]butan-1-ol
Show/Hide
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C19H20N4O
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1
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| 1 |
EC50 = 1800 nM
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CP0561832
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4-[2-(pyrazolo[3,4-c]pyridin-1-ylmethyl)benzimidazol-1-yl]butan-1-ol
Show/Hide
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C18H19N5O
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1
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| 1 |
EC50 = 2200 nM
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CP0486175
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N'-[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C20H22N4
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1
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| 1 |
EC50 = 2300 nM
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CP0513364
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2-[2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]amino]ethyl]guanidine
Show/Hide
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C21H24N6
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1
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| 1 |
EC50 = 2300 nM
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CP0493124
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1-(2-methylsulfonylethyl)-2-[(3-methylsulfonylindol-1-yl)methyl]benzimidazole
Show/Hide
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C20H21N3O4S2
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1
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| 1 |
EC50 = 2414 nM
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CP0558762
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N-[2-[[2-(8-fluoro-1,3,4,5-tetrahydro-2-benzazepin-2-yl)-6-methylquinolin-4-yl]amino]ethyl]acetamide
Show/Hide
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C24H27FN4O
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1
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| 1 |
EC50 = 3100 nM
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CP0472922
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4-[2-(1,2,3,4-tetrahydropyrido[3,4-b]indol-9-ylmethyl)benzimidazol-1-yl]butan-1-ol
Show/Hide
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C23H26N4O
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1
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| 1 |
EC50 = 5000 nM
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CP0478148
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1-(2-methylsulfonylethyl)-2-[(1-methylsulfonylindol-3-yl)methyl]benzimidazole
Show/Hide
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C20H21N3O4S2
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1
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| 1 |
EC50 = 5420 nM
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CP0429414
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N'-[6-methylsulfonyl-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C22H26N4O2S
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1
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| 1 |
EC50 = 5600 nM
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CP0558754
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N'-[5-chloro-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C21H23ClN4
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1
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| 1 |
EC50 = 6600 nM
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CP0563169
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N'-[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]propane-1,3-diamine
Show/Hide
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C21H24N4
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1
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| 1 |
EC50 = 7800 nM
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CP0574805
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1'-[[5-cyclohexyl-1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]spiro[cyclopropane-1,3'-indole]-2'-one
Show/Hide
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C28H33N3O2
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1
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| 1 |
EC50 > 10000 nM
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CP0559033
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4-[2-[(3-methyl-4,5,6,7-tetrahydroindazol-1-yl)methyl]benzimidazol-1-yl]butan-1-ol
Show/Hide
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C20H26N4O
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1
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| 1 |
EC50 = 12000 nM
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CP0563171
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2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]amino]ethylurea
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C21H23N5O
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1
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| 1 |
EC50 = 15000 nM
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CP0396352
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3-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]amino]propane-1,2-diol
Show/Hide
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C21H23N3O2
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1
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| 1 |
EC50 = 22000 nM
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CP0472921
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4-[2-[(3-methyl-4,5,6,7-tetrahydroindazol-2-yl)methyl]benzimidazol-1-yl]butan-1-ol
Show/Hide
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C20H26N4O
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1
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| 1 |
EC50 = 26000 nM
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CP0561835
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3-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C25H31N5O2
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1
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| 1 |
EC50 > 50000 nM
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CP0464957
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1-(2-methylsulfonylethyl)-2-[(2-methylsulfonylindol-1-yl)methyl]benzimidazole
Show/Hide
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C20H21N3O4S2
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1
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| 1 |
EC50 = 100000 nM
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CP0429416
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1-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]amino]propan-2-ol
Show/Hide
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C21H23N3O
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1
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| 1 |
EC50 > 100000 nM
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CP0486176
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N'-[2-(3,4-dihydro-1H-isoquinolin-2-yl)quinolin-4-yl]butane-1,4-diamine
Show/Hide
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C22H26N4
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1
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| 1 |
EC50 > 100000 nM
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CP0569238
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1-amino-3-[[2-(1,3-dihydroisoindol-2-yl)quinolin-4-yl]amino]propan-2-ol
Show/Hide
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C20H22N4O
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1
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| 1 |
EC50 > 100000 nM
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CP0412121
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N'-[7-chloro-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)quinolin-4-yl]ethane-1,2-diamine
Show/Hide
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C21H23ClN4
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1
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| 1 |
EC50 > 3200 nM
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