General Information of the Cell Line
Cell Line ID
CL000885
Cell Line Name
HeLa-T5
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01546, ATP-dependent translocase ABCB1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0500821
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-methyl-N-(3,4,5-trimethoxy-phenyl)-acetamide
   Show/Hide
C29H26ClN3O6
  1
1
EC50 = 640 nM
 Bioactivity Info 
   TI
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CP0393257
 Compound Info 
2-(3-(9-chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)phenyl)-N-(3,4,5-trimethoxyphenyl)acetamide
   Show/Hide
C28H24ClN3O6
  1
1
EC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0392204
 Compound Info 
N-[[3-(9-chloro-3-methyl-4-oxo-[1,2]oxazolo[4,3-c]quinolin-5-yl)phenyl]methyl]-3,4,5-trimethoxybenzamide
   Show/Hide
C28H24ClN3O6
  1
1
EC50 = 1130 nM
 Bioactivity Info 
   TI
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CP0501435
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(4-hydroxy-3,5-dimethoxy-phenyl)-acetamide
   Show/Hide
C27H22ClN3O6
  1
1
EC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383916
 Compound Info 
9-Chloro-3-methyl-5-{3-[2-(3,4,5-trimethoxy-phenoxy)-ethyl]-phenyl}-5H-isoxazolo[4,3-c]quinolin-4-one
   Show/Hide
C28H25ClN2O6
  1
1
EC50 = 1470 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0501674
 Compound Info 
9-Chloro-3-methyl-5-{3-[(3,4,5-trimethoxy-benzylamino)-methyl]-phenyl}-5H-isoxazolo[4,3-c]quinolin-4-one
   Show/Hide
C28H26ClN3O5
  1
1
EC50 = 1770 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0495762
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(3-methoxy-phenyl)-acetamide
   Show/Hide
C26H20ClN3O4
  1
1
EC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0502753
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(3,5-dimethoxy-phenyl)-acetamide
   Show/Hide
C27H22ClN3O5
  1
1
EC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0409788
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-phenyl-acetamide
   Show/Hide
C25H18ClN3O3
  1
1
EC50 = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0529736
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(4-fluoro-phenyl)-acetamide
   Show/Hide
C25H17ClFN3O3
  1
1
EC50 = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528807
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-p-tolyl-acetamide
   Show/Hide
C26H20ClN3O3
  1
1
EC50 = 3700 nM
 Bioactivity Info 
   TI
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   LO
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CP0431117
 Compound Info 
N-(1,3-benzodioxol-5-yl)-2-[3-(9-chloro-3-methyl-4-oxo-[1,2]oxazolo[4,3-c]quinolin-5-yl)phenyl]acetamide
   Show/Hide
C26H18ClN3O5
  1
1
EC50 = 4000 nM
 Bioactivity Info 
   TI
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CP0511240
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(3,4-dimethoxy-phenyl)-acetamide
   Show/Hide
C27H22ClN3O5
  1
1
EC50 = 4100 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0493637
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(4-cyano-phenyl)-acetamide
   Show/Hide
C26H17ClN4O3
  1
1
EC50 = 4900 nM
 Bioactivity Info 
   TI
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   LO
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CP0383917
 Compound Info 
5-Methyl-isoxazole-3-carboxylic acid 3-(9-chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-benzylamide
   Show/Hide
C23H17ClN4O4
  1
1
EC50 = 7900 nM
 Bioactivity Info 
   TI
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   TS
CP0462338
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(4-sulfamoyl-phenyl)-acetamide
   Show/Hide
C25H19ClN4O5S
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
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   TS
CP0495963
 Compound Info 
N-(4-tert-butylphenyl)-2-[3-(9-chloro-3-methyl-4-oxo-[1,2]oxazolo[4,3-c]quinolin-5-yl)phenyl]acetamide
   Show/Hide
C29H26ClN3O3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
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CP0497109
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(4-methoxy-phenyl)-acetamide
   Show/Hide
C26H20ClN3O4
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0509886
 Compound Info 
5-Methyl-isoxazole-3-carboxylic acid [(1R,2R)-6-(9-chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-2-hydroxy-indan-1-yl]-amide
   Show/Hide
C25H19ClN4O5
  1
1
EC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0509948
 Compound Info 
2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-N-(4-trifluoromethyl-phenyl)-acetamide
   Show/Hide
C26H17ClF3N3O3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
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CP0514298
 Compound Info 
4-{2-[3-(9-Chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-phenyl]-acetylamino}-benzoic acid methyl ester
   Show/Hide
C27H20ClN3O5
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0911226
 Compound Info 
5-Methyl-isoxazole-3-carboxylic acid 4-(9-chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-benzylamide
   Show/Hide
C23H17ClN4O4
  1
1
EC50 >> 10000 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0950696
 Compound Info 
5-Methyl-isoxazole-3-carboxylic acid 2-(9-chloro-3-methyl-4-oxo-4H-isoxazolo[4,3-c]quinolin-5-yl)-benzylamide
   Show/Hide
C23H17ClN4O4
  1
1
EC50 >> 10000 nM
 Bioactivity Info 
   TI
   LI
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   TS
Protein ID: PT02516, Multidrug resistance-associated protein 1
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma