Brief Information of the Cell Line and Protein
Cell Line ID: CL000885 , HeLa-T5
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT02516 , Multidrug resistance-associated protein 1
Gene Name ABCC1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P33527
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000885  Protein ID: PT02516
 
Compound ID Compound Name Compound Formula
CP0427334
N-[[(1R,3S)-3-(9-chloro-3-methyl-4-oxo-[1,2]oxazolo[4,3-c]quinolin-5-yl)cyclohexyl]methyl]benzamide
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C25H24ClN3O3
 1
1
EC50 = 93 nM
   TI
   LI
   LO
   TS
CP0503983
N-[4-[6-hydroxy-3-[4-(2-piperidin-1-ylethoxy)benzoyl]-1-benzothiophen-2-yl]phenyl]-N-methylsulfonylmethanesulfonamide
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C30H32N2O7S3
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0393257
2-(3-(9-chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)phenyl)-N-(3,4,5-trimethoxyphenyl)acetamide
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C28H24ClN3O6
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0078757
(E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(3-(dimethylamino)-3-oxopropylthio)methylthio)propanoic acid
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C26H27ClN2O3S2
 2
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
2
Ki = 600 nM
   TI
   LI
   LO
   TS