General Information of the Protein
Protein ID
PT02516
Protein Name
Multidrug resistance-associated protein 1
Secondarily
Protein Name
ATP-binding cassette sub-family C member 1
Glutathione-S-conjugate-translocating ATPase ABCC1
Leukotriene C(4) transporter
Gene Name
ABCC1
Secondarily
Gene Name
MRP
MRP1
Sequence
MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV
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Organism
Homo sapiens, Human
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCC subfamily
Function
Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:9281595). Hydrolyzes ATP with low efficiency (PubMed:16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed:17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity). Mediates ATP-dependent, GSH-independent cyclic GMP-AMP (cGAMP) export (PubMed:36070769). Thus, by limiting intracellular cGAMP concentrations negatively regulates the cGAS-STING pathway (PubMed:36070769).
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Uniprot ID
Primary ID:
P33527

Secondarily ID:
A3RJX2
C9JPJ4
O14819
O43333
P78419
Q59GI9
Q9UQ97
Q9UQ99
Q9UQA0
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Ensembl ID
ENSG00000103222
HGNC ID
HGNC:51
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000895 , 2008/MRP1
Compound ID Compound Name Compound Formula
CP0874272
2,2'-(4,4'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diylbis(oxy))bis(4,1-phenylene))bis(7-methyl-4H-chromen-4-one)
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C44H46O11
 1
1
Activity = 86 nM
   TI
   LI
   LO
   TS
CP0861780
2,2'-(4,4'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diylbis(oxy))bis(4,1-phenylene))bis(6-methyl-4H-chromen-4-one)
   Show/Hide
C44H46O11
 1
1
Activity = 105 nM
   TI
   LI
   LO
   TS
CP0874271
2,2'-(4,4'-(3,6,9,12-tetraoxatetradecane-1,14-diylbis(oxy))bis(4,1-phenylene))bis(7-methyl-4H-chromen-4-one)
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C42H42O10
 1
1
Activity = 133 nM
   TI
   LI
   LO
   TS
CP0392216
7-[2-[2-[4-[3-[4-(7-fluoro-4-oxochromen-2-yl)phenoxy]propyl]triazol-1-yl]ethoxy]ethoxy]-2-phenylchromen-4-one
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C39H32FN3O7
 1
1
EC50 = 53 nM
   TI
   LI
   LO
   TS
CP0381563
1,16-Bis[40-((6-methyl)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13,16-hexaoxahexadecane
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C42H42O10
 3
1
EC50 = 73 nM
   TI
   LI
   LO
   TS
2
Ki = 190 nM
   TI
   LI
   LO
   TS
3
Ki = 200 nM
   TI
   LI
   LO
   TS
CP0405360
7-[2-[benzyl-[[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
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C46H40N4O7
 1
1
EC50 = 78 nM
   TI
   LI
   LO
   TS
CP0455369
7-[4-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]butoxy]-2-phenylchromen-4-one
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C40H35N3O7
 1
1
EC50 = 87 nM
   TI
   LI
   LO
   TS
CP0421418
7-[3-[1-[2-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]-2-phenylchromen-4-one
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C41H36FN3O8
 1
1
EC50 = 95 nM
   TI
   LI
   LO
   TS
CP0394398
7-[2-[benzyl-[[1-[2-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
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C48H44N4O8
 1
1
EC50 = 99 nM
   TI
   LI
   LO
   TS
CP0392219
7-fluoro-2-[4-[3-[1-[2-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]chromen-4-one
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C41H35F2N3O8
 1
1
EC50 = 103 nM
   TI
   LI
   LO
   TS
CP0392220
6-methyl-2-[4-[4-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]butoxy]phenyl]chromen-4-one
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C41H37N3O7
 1
1
EC50 = 103 nM
   TI
   LI
   LO
   TS
CP0392218
2-[4-[3-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]chromen-4-one
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C39H33N3O7
 1
1
EC50 = 113 nM
   TI
   LI
   LO
   TS
CP0405491
2-[4-[2-[2-[2-[4-[3-[4-(7-fluoro-4-oxochromen-2-yl)phenoxy]propyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-6-methylchromen-4-one
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C42H38FN3O8
 1
1
EC50 = 121 nM
   TI
   LI
   LO
   TS
CP0405492
6-methyl-2-[4-[4-[1-[2-[2-[2-[4-(6-methyl-4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]butoxy]phenyl]chromen-4-one
   Show/Hide
C44H43N3O8
 1
1
EC50 = 137 nM
   TI
   LI
   LO
   TS
CP0394401
7-fluoro-2-[4-[3-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]chromen-4-one
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C39H32FN3O7
 1
1
EC50 = 140 nM
   TI
   LI
   LO
   TS
CP0394395
7-[3-[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]propoxy]-2-phenylchromen-4-one
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C39H33N3O7
 1
1
EC50 = 151 nM
   TI
   LI
   LO
   TS
CP0394430
7-[2-[benzyl-[[1-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
   Show/Hide
C46H39FN4O7
 1
1
EC50 = 155 nM
   TI
   LI
   LO
   TS
CP0437292
7-[2-[benzyl-[[1-[2-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]amino]ethoxy]-2-phenylchromen-4-one
   Show/Hide
C48H43FN4O8
 1
1
EC50 = 156 nM
   TI
   LI
   LO
   TS
CP0392215
6-methyl-2-[4-[4-[1-[2-[2-(4-oxo-2-phenylchromen-7-yl)oxyethoxy]ethyl]triazol-4-yl]butoxy]phenyl]chromen-4-one
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C41H37N3O7
 1
1
EC50 = 175 nM
   TI
   LI
   LO
   TS
CP0392714
2-[4-[2-[2-[2-[4-[2-(4-oxo-2-phenylchromen-7-yl)oxyethoxymethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-3-phenylmethoxychromen-4-one
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C48H43N3O10
 1
1
EC50 = 193 nM
   TI
   LI
   LO
   TS
CP0405489
7-fluoro-2-[4-[3-[1-[2-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]chromen-4-one
   Show/Hide
C41H36FN3O8
 1
1
EC50 = 208 nM
   TI
   LI
   LO
   TS
CP0438147
2-[4-[4-[1-[2-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]butoxy]phenyl]-6-methylchromen-4-one
   Show/Hide
C43H40FN3O8
 1
1
EC50 = 217 nM
   TI
   LI
   LO
   TS
CP0426779
2-[4-[4-[1-[2-[2-[4-(6-fluoro-4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]butoxy]phenyl]-6-methylchromen-4-one
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C41H36FN3O7
 1
1
EC50 = 250 nM
   TI
   LI
   LO
   TS
CP0392213
7-[2-[[1-[2-[2-[4-(4-oxochromen-2-yl)phenoxy]ethoxy]ethyl]triazol-4-yl]methoxy]ethoxy]-2-phenylchromen-4-one
   Show/Hide
C39H33N3O8
 1
1
EC50 = 263 nM
   TI
   LI
   LO
   TS
CP0392214
7-[3-[1-[2-[2-(4-oxo-2-phenylchromen-7-yl)oxyethoxy]ethyl]triazol-4-yl]propoxy]-2-phenylchromen-4-one
   Show/Hide
C39H33N3O7
 1
1
EC50 = 298 nM
   TI
   LI
   LO
   TS
CP0494143
methyl 3-[[2-[4-[2-[2-[2-[4-[[benzyl(2-hydroxyethyl)amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C42H44N4O9
 2
1
EC50 = 592 nM
   TI
   LI
   LO
   TS
2
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0559073
methyl 3-[[2-[4-[2-[2-[4-[[benzyl(methyl)amino]methyl]triazol-1-yl]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C39H38N4O7
 2
1
EC50 = 681 nM
   TI
   LI
   LO
   TS
2
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0487253
methyl 3-[[2-[4-[2-[2-[2-[4-[4-(4-formylphenoxy)butyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C43H43N3O10
 1
1
EC50 = 865 nM
   TI
   LI
   LO
   TS
CP0487252
methyl 3-[[2-[4-[4-(1-benzyltriazol-4-yl)butoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C37H33N3O6
 2
1
EC50 = 886 nM
   TI
   LI
   LO
   TS
2
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0141589
3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester
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C26H35N3O5
 1
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0915258
tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-7-oxo-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate
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C26H37N3O4
 2
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS
2
EC50 = 1950 nM
   TI
   LI
   LO
   TS
CP0036382
CAS_52-53-9
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C27H38N2O4
 3
1
EC50 = 1925 nM
   TI
   LI
   LO
   TS
2
Ki = 13200 nM
   TI
   LI
   LO
   TS
3
Ki = 13400 nM
   TI
   LI
   LO
   TS
CP0078757
(E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(3-(dimethylamino)-3-oxopropylthio)methylthio)propanoic acid
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C26H27ClN2O3S2
 1
1
EC50 = 19000 nM
   TI
   LI
   LO
   TS
CP0487254
methyl 3-[[2-[4-[2-[2-[4-[(dibenzylamino)methyl]triazol-1-yl]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C45H42N4O7
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0527500
methyl 3-[[2-[4-[4-[1-[2-(2-hydroxyethoxy)ethyl]triazol-4-yl]butoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C34H35N3O8
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0527501
methyl 3-[[2-[4-[2-[2-[2-[4-[[benzyl(methyl)amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C41H42N4O8
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0527503
methyl 3-[[2-(4-hex-5-ynoxyphenyl)-4-oxochromen-3-yl]oxymethyl]benzoate
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C30H26O6
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0531378
methyl 3-[[2-[4-[2-(2-azidoethoxy)ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C28H25N3O7
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0531379
methyl 3-[[2-[4-[2-[2-[2-[4-[2-(1,3-dioxoisoindol-2-yl)ethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C42H38N4O10
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0531380
methyl 3-[[2-[4-[2-[2-[4-[2-(1,3-dioxoisoindol-2-yl)ethyl]triazol-1-yl]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
   Show/Hide
C40H34N4O9
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0544327
methyl 3-[[2-[4-[2-[2-[4-(anilinomethyl)triazol-1-yl]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C37H34N4O7
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0547453
methyl 3-[[2-[4-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C30H29N3O8
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0421254
methyl 3-[[2-[4-[2-[2-[4-[3-[1-[2-[2-[4-[3-[(3-methoxycarbonylphenyl)methoxy]-4-oxochromen-2-yl]phenoxy]ethoxy]ethyl]triazol-4-yl]phenyl]triazol-1-yl]ethoxy]ethoxy]phenyl]-4-oxochromen-3-yl]oxymethyl]benzoate
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C66H56N6O14
 1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS
CP0002490
1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis(oxidanyl)anthracene-9,10-dione;hydrochloride
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C22H28N4O6
 1
1
IC50 = 27.5 nM
   TI
   LI
   LO
   TS
CP0433749
[(2R,3S)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 4-fluoro-3-[(3,4,5-trimethoxybenzoyl)amino]benzoate
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C37H38FNO12
 1
1
IC50 = 141 nM
   TI
   LI
   LO
   TS
CP0400853
[(2R,3S)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3-[(3,4-dimethoxybenzoyl)amino]-4-fluorobenzoate
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C36H36FNO11
 1
1
IC50 = 142 nM
   TI
   LI
   LO
   TS
CP0376150
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] (E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate
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C32H36O11
 1
1
IC50 = 322 nM
   TI
   LI
   LO
   TS
CP0376151
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 4-fluoro-3-[(3,4,5-trimethoxybenzoyl)amino]benzoate
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C37H38FNO12
 1
1
IC50 = 418 nM
   TI
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   LO
   TS
CP0376714
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3-[(3,4-dimethoxybenzoyl)amino]-4-fluorobenzoate
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C36H36FNO11
 1
1
IC50 = 434 nM
   TI
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   TS
Biochemical Assays
Compound ID Compound Name Compound Formula
CP0398467
4-[4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol
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C24H25NO3
 1
1 EC50 = 9300 nM
CP0036222
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
   Show/Hide
C62H111N11O12
 1
1 IC50 = 1412 nM
CP0141589
3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester
   Show/Hide
C26H35N3O5
 1
1 IC50 = 2000 nM
CP0026719
3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
   Show/Hide
C15H10O8
 1
1 IC50 = 20000 nM
CP0171970
4-Phenethylamino-6,7,8,9-tetrahydro-pyrimido[4,5-b]indolizine-10-carbonitrile
   Show/Hide
C19H19N5
 1
1 IC50 >= 250 nM
CP0320064
(9-Carbamoyl-4-{4-[2-(3,4-difluoro-phenyl)-ethyl]-piperazin-1-yl}-pyrimido[5,4-b]indol-5-yl)-acetic acid ethyl ester
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C27H28F2N6O3
 1
1 IC50 < 250 nM
Clinical Information about the Protein
Target 1 ( Multidrug resistance-associated protein 1 (ABCC1) )
Target Type Successful Target
Disease 1 Target-related Disease  1
1 Gout [ICD-11: FA25]
Approved Drug(s) 2 Approved Drugs  2
1 Benzbromarone Approved
Gout
2 Sulfinpyrazone Approved
Gout
Target 2 ( HUMAN multidrug resistance-associated protein 1 (ABCC1) )
Target Type Unknown Type Target