General Information of the Compound
| Compound ID |
CP0041383
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| Compound Name |
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
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| Synonyms |
(2-Ethyl-3-benzofuranyl)-(3,5-dibrom-4-hydroxyphenyl)keton
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
2-Ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran
3, 5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone
3,5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone
3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran
3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN
AL, Benzbromaron
Acifugan
Aliud Brand of Benzbromarone
Azubromaron
Benzbromaron
Benzbromaron AL
Benzbromaron ratiopharm
Benzbromaron-ratiopharm
Benzbromarone
Benzbromarone (JP15/USAN/INN)
Benzbromarone Aliud Brand
Benzbromarone Heumann Brand
Benzbromarone Sanfer Brand
Benzbromarone [USAN:INN:BAN]
Benzbromarone ratiopharm Brand
Benzbromaronratiopharm
Benzbromaronum
Benzbromaronum [INN-Latin]
Benzobromarona
Benzobromarona [INN-Spanish]
Besuric
Desuric
Exurate
Harolan
Heumann Brand of Benzbromarone
Hipurik
KETONE, 3,5-DIBROMO-4-HYDROXYPHENYL 2-ETHYL-3-BENZOFURANYL
Ketone, 3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl
L 2214
L 2214-Labaz
L-2214
L2214
MJ 10061
Methanone, (3
Minuric
NCI85433
Narcaricin
Normurat
PMID27414413-Compound-Figure6right
Ratiopharm Brand of Benzbromarone
Sanfer Brand of Benzbromarone
Sanofi Winthrop Brand of Benzbromarone
Uricovac
Urinorm
Uroleap
Uroleap (TN)
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| Structure |
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| Formula |
C17H12Br2O3
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| Molecular Weight |
424.088
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| Canonical SMILES |
CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
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| InChI |
InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
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| InChIKey |
WHQCHUCQKNIQEC-UHFFFAOYSA-N
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| CAS |
3562-84-3
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03217, ATP-binding cassette sub-family C member 2
Protein ID: PT05334, ATP-binding cassette sub-family C member 4
Protein ID: PT01286, Bile acid receptor
Protein ID: PT04542, Bile salt export pump
Protein ID: PT00905, Cytochrome P450 2C9
Protein ID: PT03073, Solute carrier family 22 member 12
Clinical Information about the Compound
Drug 1 ( PMID27414413-Compound-Figure6right )
| Drug Name | PMID27414413-Compound-Figure6right | ||
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| Company | J-PHARMA CO., LTD. WEMPE, Michael, F. ENDOU, Hitoshi | ||
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