Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000036
Cell Line Name	MDCK-II
Synonyms	MDCK II MDCKII MDCK2 MDCK-2 MDCK Type II MDCKII-WT
Category	Spontaneously immortalized cell line
Organism	Canis lupus familiaris (Dog)
Cellosaurus ID	CVCL_0424
Tissue Information	Kidney
Disease	None

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT01546, ATP-dependent translocase ABCB1

Protein Info

Compound ID	Compound Name	Compound Formula
CP0391014 Compound Info	2-[4-(7-methyl-2-pyridin-3-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]-2-phenylacetamide Show/Hide	C28H30N6OS	5
1	EC50 = 361 nM Bioactivity Info	TI LI LO TS
2	GI50 = 189 nM Bioactivity Info	TI LI LO TS
3	GI50 = 376 nM Bioactivity Info	TI LI LO TS
4	GI50 = 1740 nM Bioactivity Info	TI LI LO TS
5	GI50 = 2880 nM Bioactivity Info	TI LI LO TS
CP0250552 Compound Info	(2R)-1-[4-[(2R,4S)-3,3-dichloro-11-tetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaenyl]piperazin-1-yl]-3-quinolin-5-yloxypropan-2-ol Show/Hide	C32H31Cl2N3O2	1
1	IC50 = 930 nM Bioactivity Info	TI LI LO TS
CP0845043 Compound Info	Dimethyl-{8-[5-(piperidine-1-carbothioyl)-thiophen-2-yl]-2,3,5,6-tetrahydro-1H,4H-13-thia-3a-aza-benzo[de]naphthacen-11-ylidene}-ammonium hexafluoro phosphate Show/Hide	C31H34F6N3PS3	2
1	IC50 = 2100 nM Bioactivity Info	TI LI LO TS
2	IC50 = 12000 nM Bioactivity Info	TI LI LO TS
CP0774152 Compound Info	Dimethyl-(8-phenyl-2,3,5,6-tetrahydro-1H,4H-13-thia-3a-aza-benzo[de]naphthacen-11-ylidene)-ammonium hexafluoro phosphate Show/Hide	C27H27F6N2PS	1
1	IC50 = 4700 nM Bioactivity Info	TI LI LO TS
CP0820049 Compound Info	Dimethyl-(8-phenyl-2,3,5,6-tetrahydro-1H,4H-13-selena-3a-aza-benzo[de]naphthacen-11-ylidene)-ammonium hexafluoro phosphate Show/Hide	C27H27F6N2PSe	1
1	IC50 = 4900 nM Bioactivity Info	TI LI LO TS
CP0878666 Compound Info	12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperidyl-2-thienyl-5-thiocarboxamido)-1H,5H-selenoxantheno[2,3,4-ij]quinolizin-14-ium Hexafluorophosphate Show/Hide	C31H34F6N3PS2Se	1
1	IC50 = 5300 nM Bioactivity Info	TI LI LO TS
CP0849094 Compound Info	9-(dimethylamino)-1,4,4-trimethyl-6-(5-(piperidine-1-carbonyl)thiophen-2-yl)-3,4-dihydro-2Hthiochromeno[3,2-g]quinolin-1-ium hexafluorophosphate Show/Hide	C31H36F6N3OPS2	2
1	IC50 = 5600 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13000 nM Bioactivity Info	TI LI LO TS
CP0858734 Compound Info	6-(5-(diethylcarbamoyl)thiophen-2-yl)-9-(dimethylamino)-1,4,4-trimethyl-2,3,4,6-tetrahydro-1Hthiochromeno[3,2-g]quinolin-6-ylium hexafluorophosphate Show/Hide	C30H36F6N3OPS2	2
1	IC50 = 7100 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8000 nM Bioactivity Info	TI LI LO TS
CP0852264 Compound Info	6-(5-(diethylcarbamothioyl)thiophen-2-yl)-9-(dimethylamino)-1,4,4-trimethyl-2,3,4,6-tetrahydro-1Hthiochromeno[3,2-g]quinolin-6-ylium hexafluorophosphate Show/Hide	C30H36F6N3PS3	2
1	IC50 = 8700 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8800 nM Bioactivity Info	TI LI LO TS
CP0863034 Compound Info	9-(dimethylamino)-1,4,4-trimethyl-6-(5-(piperidine-1-carbono-thioyl)thiophen-2-yl)-2,3,4,6-tetrahydro-1H-thiochromeno[3,2-g]quinolin-6-ylium hexafluorophosphate Show/Hide	C31H36F6N3PS3	2
1	IC50 = 8900 nM Bioactivity Info	TI LI LO TS
2	IC50 = 9300 nM Bioactivity Info	TI LI LO TS
CP0858736 Compound Info	3,6-Bis(dimethylamino)-9-(N-piperidyl-2-thienyl-5-thiocarboxamido)selenoxanthylium Hexafluorophosphate Show/Hide	C27H30F6N3PS2Se	1
1	IC50 = 9000 nM Bioactivity Info	TI LI LO TS
CP0036222 Compound Info	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone Show/Hide	C62H111N11O12	1
1	IC50 = 9340 nM Bioactivity Info	TI LI LO TS
CP0852103 Compound Info	12-(dimethylamino)-2,3,6,7-tetrahydro-9-(5-(diethylcarbamothioyl)-thiophen-2-yl)-1H,5H-thioxantheno[2,3,4-ij]quinolizin-14-ium hexafluorophosphate Show/Hide	C30H34F6N3PS3	1
1	IC50 = 9600 nM Bioactivity Info	TI LI LO TS
CP0852051 Compound Info	12-(dimethylamino)-2,3,6,7-tetrahydro-9-(5-(diethylcarbamoyl)thiophen-2-yl)-1H,5H-thioxantheno[2,3,4-ij]quinolizin-14-ium hexafluorophosphate Show/Hide	C30H34F6N3OPS2	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0080761 Compound Info	(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide Show/Hide	C37H48N4O5	1
1	IC50 = 10300 nM Bioactivity Info	TI LI LO TS
CP0645568 Compound Info	N-(6-(dimethylamino)-9-phenyl-3H-thioxanthen-3-ylidene)-N-methylmethanaminium bromide Show/Hide	C23H23BrN2S	1
1	IC50 = 11000 nM Bioactivity Info	TI LI LO TS
CP0675799 Compound Info	N-(6-(dimethylamino)-9-phenyl-3H-selenoxanthen-3-ylidene)-N-methylmethanaminium bromide Show/Hide	C23H23BrN2Se	1
1	IC50 = 11000 nM Bioactivity Info	TI LI LO TS
CP0858886 Compound Info	3,6-Bis(dimethylamino)-9-(N-piperidyl-2-thienyl-5-thiocarboxamido)telluroxanthylium Hexafluorophosphate Show/Hide	C27H30F6N3PS2Te	1
1	IC50 = 13000 nM Bioactivity Info	TI LI LO TS
CP0036382 Compound Info	CAS_52-53-9 Show/Hide	C27H38N2O4	1
1	IC50 = 14000 nM Bioactivity Info	TI LI LO TS
CP0904585 Compound Info	12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-morpholino-2-thienyl-5-thiocarboxamido)-1H,5H-selenoxantheno[2,3,4-ij]quinolizin-14-ium Hexafluorophosphate Show/Hide	C30H32F6N3OPS2Se	1
1	IC50 = 14000 nM Bioactivity Info	TI LI LO TS
CP0957226 Compound Info	12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperidyl-2-thienyl-5-thiocarboxamido)-1H,5H-telluroxantheno[2,3,4-ij]quinolizin-14-ium Hexafluorophosphate Show/Hide	C31H34F6N3PS2Te	1
1	IC50 = 14000 nM Bioactivity Info	TI LI LO TS
CP0856410 Compound Info	3,6-bis(dimethylamino)-9-(5-(diethylcarbamothioyl)thiophen-2-yl)thioxanthyliumhexafluorophosphate Show/Hide	C26H30F6N3PS3	1
1	IC50 = 14000 nM Bioactivity Info	TI LI LO TS
CP0765956 Compound Info	N-(6-(dimethylamino)-9-(5-(piperidine-1-carbonothioyl)thiophen-2-yl)-3H-thioxanthen-3-ylidene)-N-methylmethanaminium hexafluorophosphate Show/Hide	C27H30F6N3PS3	1
1	IC50 = 19000 nM Bioactivity Info	TI LI LO TS
CP0010655 Compound Info	(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide Show/Hide	C32H45N3O4S	1
1	IC50 = 19900 nM Bioactivity Info	TI LI LO TS
CP0904584 Compound Info	12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-morpholino-2-thienyl-5-thiocarboxamido)-1H,5H-thioxantheno[2,3,4-ij]quinolizin-14-ium Hexafluorophosphate Show/Hide	C30H32F6N3OPS3	1
1	IC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0266055 Compound Info	(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methylpropyl)sulfonamido]-3-hydroxy-1-{4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl}butan-2-yl]carbamate Show/Hide	C33H41N3O10S2	1
1	IC50 = 24100 nM Bioactivity Info	TI LI LO TS
CP0036175 Compound Info	1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate Show/Hide	C37H48N6O5S2	1
1	IC50 = 39600 nM Bioactivity Info	TI LI LO TS
CP0866748 Compound Info	12-(dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperidyl-2-thienyl-5-carboxamido)-1H,5H-thioxantheno[2,3,4-ij]quinolizin-14-ium hexafluorophosphate Show/Hide	C31H34F6N3OPS2	1
1	IC50 = 56000 nM Bioactivity Info	TI LI LO TS
CP0086074 Compound Info	Atazanavir Show/Hide	C38H52N6O7	1
1	IC50 = 67800 nM Bioactivity Info	TI LI LO TS
CP0013112 Compound Info	(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate Show/Hide	C27H37N3O7S	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS
CP0038005 Compound Info	(3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate Show/Hide	C25H35N3O6S	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS
CP0040838 Compound Info	(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide Show/Hide	C36H47N5O4	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS
CP0048327 Compound Info	(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide Show/Hide	C38H50N6O5	1
1	IC50 = 100000 nM Bioactivity Info	TI LI LO TS
CP0675512 Compound Info	3,6-bis(dimethylamino)-9-(5-(diethylcarbamoyl)thiophen-2-yl)thioxan-thyliumhexafluorophosphate Show/Hide	C26H30F6N3OPS2	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS
CP0856408 Compound Info	3,6-bis(dimethylamino)-9-(5-(piperidine-1-carbonyl)thiophen-2-yl)thio-xanthylium hexafluorophosphate Show/Hide	C27H30F6N3OPS2	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT03217, ATP-binding cassette sub-family C member 2

Protein Info

Protein ID: PT02718, ATP-binding cassette sub-family G member 2

Protein Info

Protein ID: PT05367, Multidrug and toxin extrusion protein 1

Protein Info

Protein ID: PT02516, Multidrug resistance-associated protein 1

Protein Info

Protein ID: PT04639, NPC1-like intracellular cholesterol transporter 1

Protein Info

Cell Viability or Cytotoxicity Assay

Compound ID	Compound Name	Compound Formula
CP0010654 Compound Info	4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-ylamino)-3,5-dimethylbenzonitrile Show/Hide	C20H15BrN6O	1
1	IC50 = 9400 nM	TI LI LO TS
CP0141589 Compound Info	3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester Show/Hide	C26H35N3O5	3
1	GI50 = 11100 nM	TI LI LO TS
2	GI50 = 12500 nM	TI LI LO TS
3	GI50 = 12600 nM	TI LI LO TS
CP0201944 Compound Info	N-(3,4-dimethoxyphenyl)-2-[4-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]phenoxy]acetamide Show/Hide	C26H25NO6	1
1	GI50 = 33200 nM	TI LI LO TS
CP0256321 Compound Info	2-[4-[(E)-3-(2,6-difluorophenyl)prop-2-enoyl]phenoxy]-N-(3,4-dimethoxyphenyl)acetamide Show/Hide	C25H21F2NO5	1
1	GI50 = 36200 nM	TI LI LO TS
CP0388004 Compound Info	N-(3,4-dimethoxyphenyl)-2-phenylquinazolin-4-amine Show/Hide	C22H19N3O2	1
1	GI50 = 22500 nM	TI LI LO TS
CP0389267 Compound Info	4-[(2-phenylpyrido[2,3-d]pyrimidin-4-yl)amino]benzonitrile Show/Hide	C20H13N5	1
1	GI50 > 100000 nM	TI LI LO TS
CP0389584 Compound Info	N-(4-methoxyphenyl)-6-nitro-2-pyridin-4-ylquinazolin-4-amine Show/Hide	C20H15N5O3	2
1	GI50 = 84500 nM	TI LI LO TS
2	GI50 = 125000 nM	TI LI LO TS
CP0389587 Compound Info	N-(3-methoxyphenyl)-6-nitro-2-phenylquinazolin-4-amine Show/Hide	C21H16N4O3	1
1	GI50 = 6920 nM	TI LI LO TS
CP0389669 Compound Info	2-nitro-4-[[6-nitro-2-[3-(trifluoromethyl)phenyl]quinazolin-4-yl]amino]phenol Show/Hide	C21H12F3N5O5	2
1	GI50 = 24100 nM	TI LI LO TS
2	GI50 = 27400 nM	TI LI LO TS
CP0389670 Compound Info	N,2-diphenylquinazolin-4-amine Show/Hide	C20H15N3	2
1	GI50 = 26000 nM	TI LI LO TS
2	GI50 = 26600 nM	TI LI LO TS
CP0389672 Compound Info	N-(3,4-dimethoxyphenyl)-6-nitro-2-phenylquinazolin-4-amine Show/Hide	C22H18N4O4	1
1	GI50 = 8130 nM	TI LI LO TS
CP0389950 Compound Info	N-(3-fluorophenyl)-2-phenylquinazolin-4-amine Show/Hide	C20H14FN3	1
1	GI50 = 27500 nM	TI LI LO TS
CP0390839 Compound Info	(E)-3-(3,4-dimethoxyphenyl)-1-[3-[[2-(3,4-dimethoxyphenyl)quinazolin-4-yl]amino]phenyl]prop-2-en-1-one Show/Hide	C33H29N3O5	1
1	GI50 = 12600 nM	TI LI LO TS
CP0391014 Compound Info	2-[4-(7-methyl-2-pyridin-3-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]-2-phenylacetamide Show/Hide	C28H30N6OS	1
1	GI50 = 42400 nM	TI LI LO TS
CP0391063 Compound Info	(E)-1-(4-hydroxyphenyl)-3-(4-propoxyphenyl)prop-2-en-1-one Show/Hide	C18H18O3	1
1	GI50 = 31100 nM	TI LI LO TS
CP0391067 Compound Info	2-[2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(1-oxo-3H-2-benzofuran-5-yl)acetamide Show/Hide	C25H16ClNO6	1
1	GI50 = 67600 nM	TI LI LO TS
CP0391069 Compound Info	2-[3-(4-methoxyphenyl)-4-oxochromen-2-yl]oxy-N-naphthalen-1-ylacetamide Show/Hide	C28H21NO5	1
1	GI50 > 100000 nM	TI LI LO TS
CP0392202 Compound Info	N-(3-methylsulfanylphenyl)-2-phenylpyrido[2,3-d]pyrimidin-4-amine Show/Hide	C20H16N4S	1
1	GI50 > 100000 nM	TI LI LO TS
CP0393137 Compound Info	N-(3,4-dimethoxyphenyl)-2-(3-methoxyphenyl)quinazolin-4-amine Show/Hide	C23H21N3O3	1
1	GI50 = 9290 nM	TI LI LO TS
CP0395159 Compound Info	N-(2-phenylquinazolin-4-yl)benzamide Show/Hide	C21H15N3O	1
1	GI50 = 128000 nM	TI LI LO TS
CP0395884 Compound Info	4-[(2-phenylquinazolin-4-yl)amino]phenol Show/Hide	C20H15N3O	1
1	GI50 = 14600 nM	TI LI LO TS
CP0398050 Compound Info	4-methoxy-N-[2-[2-(4-propylphenyl)tetrazol-5-yl]phenyl]benzamide Show/Hide	C24H23N5O2	1
1	GI50 = 63200 nM	TI LI LO TS
CP0398098 Compound Info	4-methoxy-N-[2-[2-[4-(trifluoromethyl)phenyl]tetrazol-5-yl]phenyl]benzamide Show/Hide	C22H16F3N5O2	2
1	GI50 = 34400 nM	TI LI LO TS
2	GI50 = 40200 nM	TI LI LO TS
CP0408063 Compound Info	4-[(2-pyridin-3-ylquinazolin-4-yl)amino]benzonitrile Show/Hide	C20H13N5	1
1	GI50 = 104000 nM	TI LI LO TS
CP0409100 Compound Info	4-[[2-(3-methoxyphenyl)-6-nitroquinazolin-4-yl]amino]benzonitrile Show/Hide	C22H15N5O3	1
1	GI50 = 9120 nM	TI LI LO TS
CP0410353 Compound Info	3-[(2-pyridin-4-ylquinazolin-4-yl)amino]benzonitrile Show/Hide	C20H13N5	1
1	GI50 = 88100 nM	TI LI LO TS
CP0412385 Compound Info	N-[2-(4-phenyltriazol-1-yl)phenyl]benzamide Show/Hide	C21H16N4O	1
1	GI50 = 506000 nM	TI LI LO TS
CP0412739 Compound Info	N-[2-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide Show/Hide	C21H15N3O2	2
1	GI50 = 60800 nM	TI LI LO TS
2	GI50 = 73700 nM	TI LI LO TS
CP0415982 Compound Info	2-[3-(3,4-dimethoxyphenyl)-4-oxochromen-2-yl]oxy-N-naphthalen-1-ylacetamide Show/Hide	C29H23NO6	1
1	GI50 > 100000 nM	TI LI LO TS
CP0416870 Compound Info	2-(3,4-dimethoxyphenyl)-N-(3-methoxyphenyl)quinazolin-4-amine Show/Hide	C23H21N3O3	1
1	GI50 = 14400 nM	TI LI LO TS
CP0420361 Compound Info	4-[(6-methyl-2-phenylpyrimidin-4-yl)amino]-2-nitrophenol Show/Hide	C17H14N4O3	1
1	GI50 = 49000 nM	TI LI LO TS
CP0420847 Compound Info	3-[[2-(1H-pyrrol-2-yl)quinazolin-4-yl]amino]benzonitrile Show/Hide	C19H13N5	1
1	GI50 = 38800 nM	TI LI LO TS
CP0424456 Compound Info	N-(3-nitrophenyl)-2-thiophen-2-ylquinazolin-4-amine Show/Hide	C18H12N4O2S	1
1	GI50 = 14800 nM	TI LI LO TS
CP0424457 Compound Info	N-(4-nitrophenyl)-2-thiophen-2-ylquinazolin-4-amine Show/Hide	C18H12N4O2S	1
1	GI50 = 105000 nM	TI LI LO TS
CP0424839 Compound Info	4-[[6-(butylamino)-2-phenylpyrimidin-4-yl]amino]benzonitrile Show/Hide	C21H21N5	2
1	GI50 = 6080 nM	TI LI LO TS
2	GI50 = 8320 nM	TI LI LO TS
CP0425266 Compound Info	4-[[2-phenyl-6-(propylamino)pyrimidin-4-yl]amino]benzonitrile Show/Hide	C20H19N5	1
1	GI50 = 8340 nM	TI LI LO TS
CP0425267 Compound Info	4-[[2-phenyl-6-(pyridin-2-ylmethylamino)pyrimidin-4-yl]amino]benzonitrile Show/Hide	C23H18N6	1
1	GI50 = 8560 nM	TI LI LO TS
CP0425271 Compound Info	4-[[6-(benzylamino)-2-phenylpyrimidin-4-yl]amino]benzonitrile Show/Hide	C24H19N5	1
1	GI50 = 4190 nM	TI LI LO TS
CP0427176 Compound Info	3-[[6-nitro-2-[3-(trifluoromethyl)phenyl]quinazolin-4-yl]amino]phenol Show/Hide	C21H13F3N4O3	1
1	GI50 = 3020 nM	TI LI LO TS
CP0427812 Compound Info	4-nitro-N-(2-phenylquinazolin-4-yl)benzamide Show/Hide	C21H14N4O3	2
1	GI50 = 904 nM	TI LI LO TS
2	GI50 = 1800 nM	TI LI LO TS
CP0430189 Compound Info	2-nitro-4-[(2-phenylquinazolin-4-yl)amino]phenol Show/Hide	C20H14N4O3	1
1	GI50 = 152000 nM	TI LI LO TS
CP0430536 Compound Info	N-(4-iodophenyl)-2-(3-nitrophenyl)quinazolin-4-amine Show/Hide	C20H13IN4O2	1
1	GI50 = 3160 nM	TI LI LO TS
CP0440750 Compound Info	N-(3-fluorophenyl)-2-(3-methoxyphenyl)-6-nitroquinazolin-4-amine Show/Hide	C21H15FN4O3	1
1	GI50 = 11200 nM	TI LI LO TS
CP0444582 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(furan-2-yl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C29H31N5O4	1
1	IC50 > 100000 nM	TI LI LO TS
CP0457689 Compound Info	6-nitro-N,2-diphenylquinazolin-4-amine Show/Hide	C20H14N4O2	1
1	GI50 = 36100 nM	TI LI LO TS
CP0466206 Compound Info	N-(6-methyl-2-phenylpyrimidin-4-yl)quinolin-6-amine Show/Hide	C20H16N4	1
1	GI50 = 38400 nM	TI LI LO TS
CP0469970 Compound Info	3-[(2-pyridin-3-ylquinazolin-4-yl)amino]benzonitrile Show/Hide	C20H13N5	1
1	GI50 = 75300 nM	TI LI LO TS
CP0469971 Compound Info	3-N,3-N-dimethyl-1-N-(2-pyridin-3-ylquinazolin-4-yl)benzene-1,3-diamine Show/Hide	C21H19N5	1
1	GI50 = 10000 nM	TI LI LO TS
CP0469972 Compound Info	N-(3-fluorophenyl)-2-pyridin-3-ylquinazolin-4-amine Show/Hide	C19H13FN4	2
1	GI50 = 46800 nM	TI LI LO TS
2	GI50 = 100000 nM	TI LI LO TS
CP0472386 Compound Info	3-[(6-methyl-2-pyridin-4-ylpyrimidin-4-yl)amino]benzonitrile Show/Hide	C17H13N5	1
1	GI50 = 9330 nM	TI LI LO TS
CP0472388 Compound Info	2-pyridin-4-yl-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine Show/Hide	C20H13F3N4	1
1	GI50 = 12300 nM	TI LI LO TS
CP0473013 Compound Info	N-(3-chlorophenyl)-2-phenylpyrido[2,3-d]pyrimidin-4-amine Show/Hide	C19H13ClN4	1
1	GI50 > 100000 nM	TI LI LO TS
CP0477389 Compound Info	N-(3-fluorophenyl)-2-(3-methoxyphenyl)pyrido[2,3-d]pyrimidin-4-amine Show/Hide	C20H15FN4O	1
1	GI50 > 100000 nM	TI LI LO TS
CP0478881 Compound Info	2-nitro-4-[(6-nitro-2-phenylquinazolin-4-yl)amino]phenol Show/Hide	C20H13N5O5	1
1	GI50 = 9750 nM	TI LI LO TS
CP0510338 Compound Info	N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]-2-phenylacetamide Show/Hide	C23H19FN2O3	1
1	LC50 > 100000 nM	TI LI LO TS
CP0517984 Compound Info	4-methoxy-N-[2-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl]benzamide Show/Hide	C23H19N3O4	2
1	GI50 = 404000 nM	TI LI LO TS
2	GI50 = 487000 nM	TI LI LO TS
CP0518996 Compound Info	4-N-(4-methoxyphenyl)-2-pyridin-3-ylquinazoline-4,6-diamine Show/Hide	C20H17N5O	2
1	GI50 = 19100 nM	TI LI LO TS
2	GI50 = 27500 nM	TI LI LO TS
CP0531428 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(2-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C31H33N5O4	1
1	IC50 = 91360 nM	TI LI LO TS
CP0531429 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(3-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C31H33N5O4	1
1	IC50 = 72630 nM	TI LI LO TS
CP0547392 Compound Info	4-[(2-pyridin-4-ylquinazolin-4-yl)amino]phenol Show/Hide	C19H14N4O	1
1	GI50 = 55000 nM	TI LI LO TS
CP0553197 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[[4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide Show/Hide	C32H35N5O3	1
1	IC50 = 42150 nM	TI LI LO TS
CP0561038 Compound Info	(E)-3-(4-fluorophenyl)-N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]prop-2-enamide Show/Hide	C24H18F2N2O3	1
1	LC50 = 63950 nM	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Kidney)

Cell Line Name		Organism	Disease
G-402	Cell Line Info	Homo sapiens (Human)	Kidney neoplasm
A-498	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
786-O	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
SN12C	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
G-401	Cell Line Info	Homo sapiens (Human)	Rhabdoid tumor of the kidney
AU-BEK	Cell Line Info	Bos taurus (Bovine)	-
MDCK	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-I	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-MDR1	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCKII-LE	Cell Line Info	Canis lupus familiaris (Dog)	-
DK	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK2/BCRP	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-Net6	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-UT-A1-AQP1-YFP	Cell Line Info	Canis lupus familiaris (Dog)	-
CV-1	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-7	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-1	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-M6	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
OAT1-COS7	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
BS-C-1	Cell Line Info	Chlorocebus pygerythrus (Vervet monkey)	-
Vero	Cell Line Info	Chlorocebus sabaeus (Green monkey)	-
OK	Cell Line Info	Didelphis virginiana (North American opossum)	-
HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-293T	Cell Line Info	Homo sapiens (Human)	-
tsA201	Cell Line Info	Homo sapiens (Human)	-
HEK293-A	Cell Line Info	Homo sapiens (Human)	-
T-REx-293	Cell Line Info	Homo sapiens (Human)	-
HEK293-EBNA	Cell Line Info	Homo sapiens (Human)	-
Expi293F	Cell Line Info	Homo sapiens (Human)	-
Flp-In-293	Cell Line Info	Homo sapiens (Human)	-
HEK293S	Cell Line Info	Homo sapiens (Human)	-
HEK293-F	Cell Line Info	Homo sapiens (Human)	-
HEK293-EBNA1-6E	Cell Line Info	Homo sapiens (Human)	-
AD-293	Cell Line Info	Homo sapiens (Human)	-
HEK293-H	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hNOD2	Cell Line Info	Homo sapiens (Human)	-
HEK293T/17	Cell Line Info	Homo sapiens (Human)	-
293T/ACE2 [Japan 2021]	Cell Line Info	Homo sapiens (Human)	-
GripTite 293 MSR	Cell Line Info	Homo sapiens (Human)	-
HL-2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR8	Cell Line Info	Homo sapiens (Human)	-
PathHunter HEK 293 EDG1 Total GPCR Internalization	Cell Line Info	Homo sapiens (Human)	-
Flp-In-T-REx-293	Cell Line Info	Homo sapiens (Human)	-
HEKR2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue IL-6	Cell Line Info	Homo sapiens (Human)	-
HK-2 [Human kidney]	Cell Line Info	Homo sapiens (Human)	-
HEK293-FT	Cell Line Info	Homo sapiens (Human)	-
HEK-2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR4	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue CD40L	Cell Line Info	Homo sapiens (Human)	-
Expi293F GnTI-	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hNOD1	Cell Line Info	Homo sapiens (Human)	-
pEAK Rapid	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR9	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR7	Cell Line Info	Homo sapiens (Human)	-
293Ta	Cell Line Info	Homo sapiens (Human)	-
293-Dual hSTING-R232	Cell Line Info	Homo sapiens (Human)	-
HEK293-CNG	Cell Line Info	Homo sapiens (Human)	-
FreeStyle 293-F	Cell Line Info	Homo sapiens (Human)	-
PrecisION hnAChR alpha7/ric3-HEK	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer ERbeta-UAS-bla GripTite 293	Cell Line Info	Homo sapiens (Human)	-
HEK385-7	Cell Line Info	Homo sapiens (Human)	-
HEK2935	Cell Line Info	Homo sapiens (Human)	-
ACTOne CXCR4	Cell Line Info	Homo sapiens (Human)	-
HEK298	Cell Line Info	Homo sapiens (Human)	-
HEK273	Cell Line Info	Homo sapiens (Human)	-
293/GFP	Cell Line Info	Homo sapiens (Human)	-
HEK293 AequoScreen	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue Null1-v	Cell Line Info	Homo sapiens (Human)	-
HEK-GIRK-M4	Cell Line Info	Homo sapiens (Human)	-
HTLA	Cell Line Info	Homo sapiens (Human)	-
HEK293/Galpha15	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-hH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-mH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
293AD	Cell Line Info	Homo sapiens (Human)	-
HEK293T/Galpha16-gustducin 44	Cell Line Info	Homo sapiens (Human)	-
CellSensor SBE-bla HEK 293T	Cell Line Info	Homo sapiens (Human)	-
NRK1-HEK293T	Cell Line Info	Homo sapiens (Human)	-
HEK293T-SF-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-rH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-mH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-hH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-SP-FLAG-hH3R-CRE-CBR	Cell Line Info	Homo sapiens (Human)	-
293/AP1-luc	Cell Line Info	Homo sapiens (Human)	-
293GT	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer AR-UAS-bla Griptite 293	Cell Line Info	Homo sapiens (Human)	-
UAS-MR-bla HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK293-DR-GFP	Cell Line Info	Homo sapiens (Human)	-
PSC-HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-293-A2B	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-rH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
Hana3A	Cell Line Info	Homo sapiens (Human)	-
HEK293S GnTI-	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla GripTite 293	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla HEK 293H	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla HEK 293T	Cell Line Info	Homo sapiens (Human)	-
HEKMSR2	Cell Line Info	Homo sapiens (Human)	-
HEK-hNET	Cell Line Info	Homo sapiens (Human)	-
HEK-hDAT	Cell Line Info	Homo sapiens (Human)	-
HEK-hSERT	Cell Line Info	Homo sapiens (Human)	-
EE-HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-A2A	Cell Line Info	Homo sapiens (Human)	-
HEK293EM	Cell Line Info	Homo sapiens (Human)	-
293-NB2	Cell Line Info	Homo sapiens (Human)	-
HEK-SEAP	Cell Line Info	Homo sapiens (Human)	-
HEK293/Gal4	Cell Line Info	Homo sapiens (Human)	-
Octn2-HEK	Cell Line Info	Homo sapiens (Human)	-
Octn1-HEK	Cell Line Info	Homo sapiens (Human)	-
Octn3-HEK	Cell Line Info	Homo sapiens (Human)	-
HEK293superTOP	Cell Line Info	Homo sapiens (Human)	-
HEK293T-ARRB1	Cell Line Info	Homo sapiens (Human)	-
HEK293T-ARRB2	Cell Line Info	Homo sapiens (Human)	-
HEK293T-qs5-HA	Cell Line Info	Homo sapiens (Human)	-
EDG3-Ga15-bla HEK293T	Cell Line Info	Homo sapiens (Human)	-
LLC-MK2	Cell Line Info	Macaca mulatta (Rhesus macaque)	-
BHK-21	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK-21 clone 13	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK570	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
TK-TS 13	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK/AC9	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
mIMCD-3	Cell Line Info	Mus musculus (Mouse)	-
RK3E	Cell Line Info	Rattus norvegicus (Rat)	-
KNRK	Cell Line Info	Rattus norvegicus (Rat)	-
NRK-52E	Cell Line Info	Rattus norvegicus (Rat)	-
SKPT-0193 Cl.2	Cell Line Info	Rattus norvegicus (Rat)	-
RKE	Cell Line Info	Rattus norvegicus (Rat)	-
LLC-PK1	Cell Line Info	Sus scrofa (Pig)	-
LLC-GA5-CoL150	Cell Line Info	Sus scrofa (Pig)	-
PK-15	Cell Line Info	Sus scrofa (Pig)	-
HKRK-B28	Cell Line Info	Sus scrofa (Pig)	-
PK15NTD	Cell Line Info	Sus scrofa (Pig)	-

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han