Brief Information of the Cell Line and Protein
Cell Line ID: CL000036 , MDCK-II
 Cell Line Info 
Synonyms
MDCK II
MDCKII
MDCK2
MDCK-2
MDCK Type II
MDCKII-WT
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_0424
Protein ID: PT04639 , NPC1-like intracellular cholesterol transporter 1
 Protein Info 
Gene Name NPC1L1
Organism Homo sapiens, Human
Protein Classification Other membrane protein
Uniprot ID Q9UHC9
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000036
 Cell Line Info 
 Protein ID: PT04639
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0561038
 Compound Info 
(E)-3-(4-fluorophenyl)-N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]prop-2-enamide
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C24H18F2N2O3
  1
1
IC50 = 18000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0398138
 Compound Info 
(E)-N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]-3-phenylprop-2-enamide
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C24H19FN2O3
  1
1
IC50 = 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552339
 Compound Info 
2-(4-fluorophenyl)-N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]acetamide
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C23H18F2N2O3
  1
1
IC50 = 46000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0397894
 Compound Info 
4-fluoro-N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]benzamide
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C22H16F2N2O3
  1
1
IC50 = 54000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399563
 Compound Info 
N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]benzamide
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C22H17FN2O3
  1
1
IC50 = 70000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0510338
 Compound Info 
N-[(2R,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]-2-phenylacetamide
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C23H19FN2O3
  1
1
IC50 = 88000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS