Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000192
Cell Line Name	AD-293
Synonyms	Ad-293 AD293 Adeno-293 Adeno 293 HEK-AD293 HEK (AD293) HEK AD293 HEK-AD 293 AdHek
Category	Transformed cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_9804
Tissue Information	Kidney
Disease	None

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT03119, Cytochrome P450 11B1, mitochondrial

Protein Info

Compound ID	Compound Name	Compound Formula
CP0891297 Compound Info	1-(4-(4-(3-fluoro-5-(pyridin-4-yl)phenethyl)phenyl)piperazin-1-yl)ethanone Show/Hide	C25H26FN3O	1
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0392479 Compound Info	1-[4-[(E)-2-[3-chloro-5-(imidazol-1-ylmethyl)phenyl]ethenyl]phenyl]-4-pyridin-3-ylsulfonylpiperazine Show/Hide	C27H26ClN5O2S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0774136 Compound Info	1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)-4-(3-(trifluoromethoxy)phenylsulfonyl)piperazine Show/Hide	C29H26ClF3N4O3S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0883498 Compound Info	3-(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazine-1-carbonyl)benzonitrile Show/Hide	C30H26ClN5O	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0883500 Compound Info	3-(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazin-1-ylsulfonyl)benzonitrile Show/Hide	C29H26ClN5O2S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0910975 Compound Info	(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazin-1-yl)(3-nitrophenyl)methanone Show/Hide	C29H26ClN5O3	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0914790 Compound Info	1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)-4-(3-nitrophenylsulfonyl)piperazine Show/Hide	C28H26ClN5O4S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0865289 Compound Info	(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazin-1-yl)(pyridin-3-yl)methanone Show/Hide	C28H26ClN5O	1
1	IC50 = 4.9 nM Bioactivity Info	TI LI LO TS
CP0412675 Compound Info	US9725436, Entry 12 Show/Hide	C25H29FN4O2S	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0874119 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(cyclopropylsulfonyl)piperazine Show/Hide	C28H32Cl2N4O5S	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0475305 Compound Info	1-[4-[(E)-2-[3-chloro-5-(imidazol-1-ylmethyl)phenyl]ethenyl]phenyl]-4-(1H-imidazol-5-ylsulfonyl)piperazine Show/Hide	C25H25ClN6O2S	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0904003 Compound Info	3-((4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazin-1-yl)methyl)benzonitrile Show/Hide	C30H28ClN5	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0874099 Compound Info	1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)-4-(cyclopropylmethyl)piperazine Show/Hide	C26H29ClN4	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0665725 Compound Info	1-(4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazin-1-yl)ethanone Show/Hide	C27H30Cl2N4O4	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0855353 Compound Info	1-(4-(4-(((2r,5r)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazin-1-yl)ethanone Show/Hide	C27H30Cl2N4O4	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0900139 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(pyridin-3-ylsulfonyl)piperazine Show/Hide	C30H31Cl2N5O5S	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0875637 Compound Info	1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)-4-(3-chloropropylsulfonyl)piperazine Show/Hide	C25H28Cl2N4O2S	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0883496 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(3-(trifluoromethoxy)phenylsulfonyl)piperazine Show/Hide	C32H31Cl2F3N4O6S	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0849847 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(1H-imidazol-4-ylsulfonyl)piperazine Show/Hide	C28H30Cl2N6O5S	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0357005 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylimidazol-2-yl)sulfonylpiperazine Show/Hide	C28H30Cl2N6O5S	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0429489 Compound Info	US9725436, Entry 15 Show/Hide	C26H28FN5O	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0874091 Compound Info	(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazin-1-yl)(cyclopropyl)methanone Show/Hide	C26H27ClN4O	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0396651 Compound Info	1-[4-[(E)-2-[3-chloro-5-(imidazol-1-ylmethyl)phenyl]ethenyl]phenyl]-4-cyclopropylsulfonylpiperazine Show/Hide	C25H27ClN4O2S	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0390356 Compound Info	1-[4-[(E)-2-[3-chloro-5-(imidazol-1-ylmethyl)phenyl]ethenyl]phenyl]-4-ethylsulfonylpiperazine Show/Hide	C24H27ClN4O2S	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0865071 Compound Info	4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)pyridine Show/Hide	C26H23Cl2N3O3	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0429484 Compound Info	US9725436, Entry 2 Show/Hide	C23H25ClN4O2S	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0874071 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(isopropylsulfonyl)piperazine Show/Hide	C28H34Cl2N4O5S	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0766321 Compound Info	ethyl 2-(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperazine-1-carboxamido)acetate Show/Hide	C27H30ClN5O3	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0910969 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(3-chloropropylsulfonyl)piperazine Show/Hide	C28H33Cl3N4O5S	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0089866 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(difluoromethylsulfonyl)piperazine Show/Hide	C25H26Cl2F2N4O5S	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0089867 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(trifluoromethylsulfonyl)piperazine Show/Hide	C25H25Cl2F3N4O5S	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0874118 Compound Info	3-(4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazin-1-ylsulfonyl)benzonitrile Show/Hide	C32H31Cl2N5O5S	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0121431 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-propan-2-ylsulfonylpiperazine Show/Hide	C27H32Cl2N4O5S	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0383245 Compound Info	1-[4-[4-[(E)-2-[3-chloro-5-(imidazol-1-ylmethyl)phenyl]ethenyl]phenyl]piperazin-1-yl]ethanone Show/Hide	C24H25ClN4O	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0457624 Compound Info	US9725436, Entry 11 Show/Hide	C23H25FN4O2S	1
1	IC50 = 49 nM Bioactivity Info	TI LI LO TS
CP0390354 Compound Info	US9725436, Entry 7 Show/Hide	C26H26ClN3O2S	1
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
CP0865288 Compound Info	1-(4-(4-(3-((1H-imidazol-1-yl)methyl)-5-hydroxystyryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C24H26N4O2	1
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
CP0904002 Compound Info	1-(cyclopropylmethyl)-4-(4-(3-fluoro-5-(pyridin-4-yl)styryl)phenyl)piperazine Show/Hide	C27H28FN3	1
1	IC50 = 54 nM Bioactivity Info	TI LI LO TS
CP0900138 Compound Info	1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)-4-(4-chloro-3-nitrophenylsulfonyl)piperazine Show/Hide	C28H25Cl2N5O4S	1
1	IC50 = 57 nM Bioactivity Info	TI LI LO TS
CP0303595 Compound Info	1-cyclopropylsulfonyl-4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine Show/Hide	C27H30Cl2N4O5S	1
1	IC50 = 58 nM Bioactivity Info	TI LI LO TS
CP0383249 Compound Info	US9725436, Entry 8 Show/Hide	C26H28ClN3O2S	1
1	IC50 = 58 nM Bioactivity Info	TI LI LO TS
CP0324016 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-ethylsulfonylpiperazine Show/Hide	C26H30Cl2N4O5S	1
1	IC50 = 63 nM Bioactivity Info	TI LI LO TS
CP0357339 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(methylsulfonylmethylsulfonyl)piperazine Show/Hide	C26H30Cl2N4O7S2	1
1	IC50 = 67 nM Bioactivity Info	TI LI LO TS
CP0122467 Compound Info	2-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]sulfonylacetonitrile Show/Hide	C26H27Cl2N5O5S	1
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
CP0891298 Compound Info	4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-N,N-dimethylpiperazine-1-carboxamide Show/Hide	C28H34ClN5O4	1
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
CP0412679 Compound Info	2-[4-[4-[(E)-2-[3-fluoro-5-(imidazol-1-ylmethyl)phenyl]ethenyl]phenyl]piperazin-1-yl]sulfonylacetonitrile Show/Hide	C24H24FN5O2S	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0910977 Compound Info	ethyl 2-(3-(1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)piperidin-4-yl)ureido)acetate Show/Hide	C28H32ClN5O3	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0121432 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-thiophen-2-ylsulfonylpiperazine Show/Hide	C28H28Cl2N4O5S2	1
1	IC50 = 82 nM Bioactivity Info	TI LI LO TS
CP0875635 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(methylsulfonyl)piperazine Show/Hide	C26H31ClN4O5S	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0854006 Compound Info	ethyl 2-(4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazine-1-carboxamido)acetate Show/Hide	C30H36ClN5O6	1
1	IC50 = 107 nM Bioactivity Info	TI LI LO TS
CP0303596 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(2-methoxyethylsulfonyl)piperazine Show/Hide	C27H32Cl2N4O6S	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0005212 Compound Info	US8987315, Ketoconazole Show/Hide	C26H28Cl2N4O4	1
1	IC50 = 116 nM Bioactivity Info	TI LI LO TS
CP0412677 Compound Info	US9725436, Entry 14 Show/Hide	C25H26FN5O	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0412714 Compound Info	US9725436, Entry 17 Show/Hide	C25H26ClN5O	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0081085 Compound Info	1-cyclopropylsulfonyl-4-[4-[(E)-2-(3-fluoro-5-pyridin-4-ylphenyl)ethenyl]phenyl]piperazine Show/Hide	C26H26FN3O2S	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0874090 Compound Info	1-(4-(4-(3-chloro-5-((pyridin-3-yloxy)methyl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C26H26ClN3O2	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0854005 Compound Info	2-methoxyethyl 4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazine-1-carboxylate Show/Hide	C29H35ClN4O6	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0874088 Compound Info	ethyl 2-(4-(4-(3-fluoro-5-(pyridin-4-yl)phenethyl)phenyl)piperazine-1-carboxamido)acetate Show/Hide	C28H31FN4O3	1
1	IC50 = 160 nM Bioactivity Info	TI LI LO TS
CP0859774 Compound Info	1-(4-(4-(3-chloro-5-(pyridin-3-ylmethyl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C26H26ClN3O	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0902827 Compound Info	1-(4-(3-fluoro-5-(pyridin-4-yl)phenethyl)phenyl)-4-(trifluoromethylsulfonyl)piperazine Show/Hide	C24H23F4N3O2S	1
1	IC50 = 183 nM Bioactivity Info	TI LI LO TS
CP0111111 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(oxan-4-ylsulfonyl)piperazine Show/Hide	C29H34Cl2N4O6S	1
1	IC50 = 187 nM Bioactivity Info	TI LI LO TS
CP0198415 Compound Info	1-ethylsulfonyl-4-[4-[(E)-2-(3-fluoro-5-pyridin-4-ylphenyl)ethenyl]phenyl]piperazine Show/Hide	C25H26FN3O2S	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0389979 Compound Info	US9725436, Entry 3 Show/Hide	C24H24FN3O2S	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0924406 Compound Info	1-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(ethylsulfonyl)piperazine Show/Hide	C27H32Cl2N4O5S	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0910976 Compound Info	1-(4-(3-fluoro-5-(pyridin-4-yl)styryl)phenyl)-4-(pyridin-3-ylsulfonyl)piperazine Show/Hide	C28H25FN4O2S	1
1	IC50 = 220 nM Bioactivity Info	TI LI LO TS
CP0874092 Compound Info	1-(4-(3-((1H-imidazol-1-yl)methyl)-5-chlorostyryl)phenyl)-4-(isopropylsulfonyl)piperazine Show/Hide	C25H29ClN4O2S	1
1	IC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0849855 Compound Info	1-(ethylsulfonyl)-4-(4-(3-fluoro-5-(pyridin-4-yl)phenethyl)phenyl)piperazine Show/Hide	C25H28FN3O2S	1
1	IC50 = 330 nM Bioactivity Info	TI LI LO TS
CP0865287 Compound Info	1-(4-(4-(3-chloro-5-(1-hydroxy-2-methyl-1-(pyridin-3-yl)propyl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C29H32ClN3O2	1
1	IC50 = 370 nM Bioactivity Info	TI LI LO TS
CP0945763 Compound Info	4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)pyridine Show/Hide	C26H24ClN3O3	1
1	IC50 = 440 nM Bioactivity Info	TI LI LO TS
CP0476118 Compound Info	US9725436, Entry 4 Show/Hide	C24H24ClN3O2S	1
1	IC50 = 450 nM Bioactivity Info	TI LI LO TS
CP0121427 Compound Info	1-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-methylsulfonylpiperazine Show/Hide	C25H28Cl2N4O5S	1
1	IC50 = 500 nM Bioactivity Info	TI LI LO TS
CP0860881 Compound Info	1-(4-(4-(((2s,5s)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazin-1-yl)ethanone Show/Hide	C27H31ClN4O4	1
1	IC50 = 521 nM Bioactivity Info	TI LI LO TS
CP0179479 Compound Info	1-[4-[4-[(E)-2-(3-fluoro-5-pyridin-4-ylphenyl)ethenyl]phenyl]piperazin-1-yl]ethanone Show/Hide	C25H24FN3O	1
1	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
CP0457623 Compound Info	US9725436, Entry 1 Show/Hide	C23H25ClN6	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0883499 Compound Info	ethyl 2-(4-(4-(3-fluoro-5-(pyridin-4-yl)styryl)phenyl)piperazine-1-carboxamido)acetate Show/Hide	C28H29FN4O3	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0402478 Compound Info	US9725436, Entry 13 Show/Hide	C23H25FN6	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0874097 Compound Info	3-(4-bromostyryl)-5-(1H-imidazol-1-yl)phenol Show/Hide	C17H13BrN2O	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0074421 Compound Info	1-[4-[(E)-2-(3-fluoro-5-pyridin-4-ylphenyl)ethenyl]phenyl]-4-(trifluoromethylsulfonyl)piperazine Show/Hide	C24H21F4N3O2S	1
1	IC50 = 1500 nM Bioactivity Info	TI LI LO TS
CP0464846 Compound Info	US9725436, Entry 6 Show/Hide	C26H25FN4O	1
1	IC50 = 1800 nM Bioactivity Info	TI LI LO TS
CP0891294 Compound Info	1-(4-(4-(3-chloro-5-(2-methyl-1-(pyridin-3-yl)prop-1-enyl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C29H30ClN3O	1
1	IC50 = 1800 nM Bioactivity Info	TI LI LO TS
CP0536564 Compound Info	US9725436, Entry 10 Show/Hide	C26H25ClN4O	1
1	IC50 = 3500 nM Bioactivity Info	TI LI LO TS
CP0402467 Compound Info	US9725436, Entry 5 Show/Hide	C24H24FN5	1
1	IC50 = 3600 nM Bioactivity Info	TI LI LO TS
CP0910978 Compound Info	4-(3-fluoro-5-(4-(pyridin-4-yl)styryl)phenyl)pyridine Show/Hide	C24H17FN2	1
1	IC50 = 3700 nM Bioactivity Info	TI LI LO TS
CP0849853 Compound Info	1-(4-(4-(3-hydroxy-5-(1H-imidazol-1-yl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C23H24N4O2	1
1	IC50 = 4800 nM Bioactivity Info	TI LI LO TS
CP0855352 Compound Info	ethyl 2-(4-(4-(((2r,5r)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)piperazine-1-carboxamido)acetate Show/Hide	C30H36ClN5O6	1
1	IC50 = 5800 nM Bioactivity Info	TI LI LO TS
CP0402471 Compound Info	1-[4-[4-[(E)-2-(3-chloro-5-pyridin-4-ylphenyl)ethenyl]phenyl]piperazin-1-yl]ethanone Show/Hide	C25H24ClN3O	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0536483 Compound Info	US9725436, Entry 9 Show/Hide	C24H24ClN5	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0849854 Compound Info	4-(3-(4-bromostyryl)-5-fluorophenyl)pyridine Show/Hide	C19H13BrFN	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0849856 Compound Info	1-(4-(4-(3-chloro-5-(pyridin-3-yl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C25H24ClN3O	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0849857 Compound Info	4-(3-fluoro-5-(4-(pyridin-4-yl)phenethyl)phenyl)pyridine Show/Hide	C24H19FN2	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0902828 Compound Info	1-(4-(4-(3-fluoro-5-(pyridin-3-yl)styryl)phenyl)piperazin-1-yl)ethanone Show/Hide	C25H24FN3O	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0849858 Compound Info	1-(4-(((2r,5r)-2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxan-5-yloxy)methyl)phenyl)-4-(methylsulfonyl)piperazine Show/Hide	C26H31ClN4O5S	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT03374, Estrogen-related receptor gamma

Protein Info

Protein ID: PT01875, PDE10A

Protein Info

Protein ID: PT00681, Phosphodiesterase

Protein Info

Protein ID: PT01503, Signal transducer and activator of transcription 3

Protein Info

Protein ID: PT01584, Steroid 17-alpha-hydroxylase/17,20 lyase

Protein Info

Protein ID: PT05184, Steroid 21-hydroxylase

Protein Info

Protein ID: PT03343, Toll-like receptor 4

Protein Info

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Kidney)

Cell Line Name		Organism	Disease
G-402	Cell Line Info	Homo sapiens (Human)	Kidney neoplasm
A-498	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
786-O	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
SN12C	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
G-401	Cell Line Info	Homo sapiens (Human)	Rhabdoid tumor of the kidney
AU-BEK	Cell Line Info	Bos taurus (Bovine)	-
MDCK	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-II	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-I	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-MDR1	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCKII-LE	Cell Line Info	Canis lupus familiaris (Dog)	-
DK	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK2/BCRP	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-Net6	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-UT-A1-AQP1-YFP	Cell Line Info	Canis lupus familiaris (Dog)	-
CV-1	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-7	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-1	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-M6	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
OAT1-COS7	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
BS-C-1	Cell Line Info	Chlorocebus pygerythrus (Vervet monkey)	-
Vero	Cell Line Info	Chlorocebus sabaeus (Green monkey)	-
OK	Cell Line Info	Didelphis virginiana (North American opossum)	-
HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-293T	Cell Line Info	Homo sapiens (Human)	-
tsA201	Cell Line Info	Homo sapiens (Human)	-
HEK293-A	Cell Line Info	Homo sapiens (Human)	-
T-REx-293	Cell Line Info	Homo sapiens (Human)	-
HEK293-EBNA	Cell Line Info	Homo sapiens (Human)	-
Expi293F	Cell Line Info	Homo sapiens (Human)	-
Flp-In-293	Cell Line Info	Homo sapiens (Human)	-
HEK293S	Cell Line Info	Homo sapiens (Human)	-
HEK293-F	Cell Line Info	Homo sapiens (Human)	-
HEK293-EBNA1-6E	Cell Line Info	Homo sapiens (Human)	-
HEK293-H	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hNOD2	Cell Line Info	Homo sapiens (Human)	-
HEK293T/17	Cell Line Info	Homo sapiens (Human)	-
293T/ACE2 [Japan 2021]	Cell Line Info	Homo sapiens (Human)	-
GripTite 293 MSR	Cell Line Info	Homo sapiens (Human)	-
HL-2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR8	Cell Line Info	Homo sapiens (Human)	-
PathHunter HEK 293 EDG1 Total GPCR Internalization	Cell Line Info	Homo sapiens (Human)	-
Flp-In-T-REx-293	Cell Line Info	Homo sapiens (Human)	-
HEKR2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue IL-6	Cell Line Info	Homo sapiens (Human)	-
HK-2 [Human kidney]	Cell Line Info	Homo sapiens (Human)	-
HEK293-FT	Cell Line Info	Homo sapiens (Human)	-
HEK-2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR4	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue CD40L	Cell Line Info	Homo sapiens (Human)	-
Expi293F GnTI-	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hNOD1	Cell Line Info	Homo sapiens (Human)	-
pEAK Rapid	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR9	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR7	Cell Line Info	Homo sapiens (Human)	-
293Ta	Cell Line Info	Homo sapiens (Human)	-
293-Dual hSTING-R232	Cell Line Info	Homo sapiens (Human)	-
HEK293-CNG	Cell Line Info	Homo sapiens (Human)	-
FreeStyle 293-F	Cell Line Info	Homo sapiens (Human)	-
PrecisION hnAChR alpha7/ric3-HEK	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer ERbeta-UAS-bla GripTite 293	Cell Line Info	Homo sapiens (Human)	-
HEK385-7	Cell Line Info	Homo sapiens (Human)	-
HEK2935	Cell Line Info	Homo sapiens (Human)	-
ACTOne CXCR4	Cell Line Info	Homo sapiens (Human)	-
HEK298	Cell Line Info	Homo sapiens (Human)	-
HEK273	Cell Line Info	Homo sapiens (Human)	-
293/GFP	Cell Line Info	Homo sapiens (Human)	-
HEK293 AequoScreen	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue Null1-v	Cell Line Info	Homo sapiens (Human)	-
HEK-GIRK-M4	Cell Line Info	Homo sapiens (Human)	-
HTLA	Cell Line Info	Homo sapiens (Human)	-
HEK293/Galpha15	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-hH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-mH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
293AD	Cell Line Info	Homo sapiens (Human)	-
HEK293T/Galpha16-gustducin 44	Cell Line Info	Homo sapiens (Human)	-
CellSensor SBE-bla HEK 293T	Cell Line Info	Homo sapiens (Human)	-
NRK1-HEK293T	Cell Line Info	Homo sapiens (Human)	-
HEK293T-SF-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-rH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-mH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-hH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-SP-FLAG-hH3R-CRE-CBR	Cell Line Info	Homo sapiens (Human)	-
293/AP1-luc	Cell Line Info	Homo sapiens (Human)	-
293GT	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer AR-UAS-bla Griptite 293	Cell Line Info	Homo sapiens (Human)	-
UAS-MR-bla HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK293-DR-GFP	Cell Line Info	Homo sapiens (Human)	-
PSC-HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-293-A2B	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-rH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
Hana3A	Cell Line Info	Homo sapiens (Human)	-
HEK293S GnTI-	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla GripTite 293	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla HEK 293H	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla HEK 293T	Cell Line Info	Homo sapiens (Human)	-
HEKMSR2	Cell Line Info	Homo sapiens (Human)	-
HEK-hNET	Cell Line Info	Homo sapiens (Human)	-
HEK-hDAT	Cell Line Info	Homo sapiens (Human)	-
HEK-hSERT	Cell Line Info	Homo sapiens (Human)	-
EE-HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-A2A	Cell Line Info	Homo sapiens (Human)	-
HEK293EM	Cell Line Info	Homo sapiens (Human)	-
293-NB2	Cell Line Info	Homo sapiens (Human)	-
HEK-SEAP	Cell Line Info	Homo sapiens (Human)	-
HEK293/Gal4	Cell Line Info	Homo sapiens (Human)	-
Octn2-HEK	Cell Line Info	Homo sapiens (Human)	-
Octn1-HEK	Cell Line Info	Homo sapiens (Human)	-
Octn3-HEK	Cell Line Info	Homo sapiens (Human)	-
HEK293superTOP	Cell Line Info	Homo sapiens (Human)	-
HEK293T-ARRB1	Cell Line Info	Homo sapiens (Human)	-
HEK293T-ARRB2	Cell Line Info	Homo sapiens (Human)	-
HEK293T-qs5-HA	Cell Line Info	Homo sapiens (Human)	-
EDG3-Ga15-bla HEK293T	Cell Line Info	Homo sapiens (Human)	-
LLC-MK2	Cell Line Info	Macaca mulatta (Rhesus macaque)	-
BHK-21	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK-21 clone 13	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK570	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
TK-TS 13	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK/AC9	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
mIMCD-3	Cell Line Info	Mus musculus (Mouse)	-
RK3E	Cell Line Info	Rattus norvegicus (Rat)	-
KNRK	Cell Line Info	Rattus norvegicus (Rat)	-
NRK-52E	Cell Line Info	Rattus norvegicus (Rat)	-
SKPT-0193 Cl.2	Cell Line Info	Rattus norvegicus (Rat)	-
RKE	Cell Line Info	Rattus norvegicus (Rat)	-
LLC-PK1	Cell Line Info	Sus scrofa (Pig)	-
LLC-GA5-CoL150	Cell Line Info	Sus scrofa (Pig)	-
PK-15	Cell Line Info	Sus scrofa (Pig)	-
HKRK-B28	Cell Line Info	Sus scrofa (Pig)	-
PK15NTD	Cell Line Info	Sus scrofa (Pig)	-

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han