General Information of the Cell Line
Cell Line ID
CL000809
Cell Line Name
HEK273
Category
Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Tissue Information
Kidney
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01588, Corticotropin-releasing factor receptor 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0384222
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-1,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C22H28Cl2N4
  1
1
Ki = 0.62 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0373161
 Compound Info 
N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-1-ethyl-5-methyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C22H26Cl2N4
  1
1
Ki = 1.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0507461
 Compound Info 
N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-1,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C21H24Cl2N4
  1
1
Ki = 1.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0377837
 Compound Info 
Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine
   Show/Hide
C20H24Cl2N4
  1
1
Ki = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0530048
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-1-ethyl-5-methylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C23H30Cl2N4
  1
1
Ki = 2.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0453628
 Compound Info 
3-(2,4-dichlorophenyl)-1,5-dimethyl-N,N-dipropylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C20H24Cl2N4
  1
1
Ki = 3.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463623
 Compound Info 
Butyl-[3-(2,4-dichloro-phenyl)-1-ethyl-5-methyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine
   Show/Hide
C21H26Cl2N4
  1
1
Ki = 4.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0540327
 Compound Info 
3-(2,4-dichlorophenyl)-2,5-dimethyl-N,N-dipropylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C20H24Cl2N4
  1
1
Ki = 4.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0407299
 Compound Info 
N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-2,5-dimethyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C21H24Cl2N4
  1
1
Ki = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0377645
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-5-methyl-1-propan-2-ylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C24H32Cl2N4
  1
1
Ki = 16.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0946141
 Compound Info 
Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-5-methyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-propyl-amine
   Show/Hide
C20H22Cl2N4
  1
1
Ki = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0541989
 Compound Info 
N,N-dibutyl-2,5-dimethyl-3-(2,4,6-trimethylphenyl)pyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C25H36N4
  1
1
Ki = 27.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0429178
 Compound Info 
3-(2-chloro-4-methylphenyl)-N-(cyclopropylmethyl)-2-ethyl-5-methyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C23H29ClN4
  1
1
Ki = 32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0539511
 Compound Info 
Butyl-[3-(2,4-dichloro-phenyl)-2-ethyl-5-methyl-2H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine
   Show/Hide
C21H26Cl2N4
  1
1
Ki = 32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0530069
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-2,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C22H28Cl2N4
  1
1
Ki = 32.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0496384
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-2-ethyl-5-methylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C23H30Cl2N4
  1
1
Ki = 32.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0377085
 Compound Info 
Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine
   Show/Hide
C20H24Cl2N4
  1
1
Ki = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0540343
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-5-methyl-2-propan-2-ylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C24H32Cl2N4
  1
1
Ki = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0917825
 Compound Info 
Dibutyl-[3-(2,4-dichloro-phenyl)-5-methyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-amine
   Show/Hide
C21H26Cl2N4
  1
1
Ki = 40 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0515092
 Compound Info 
N-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-2-ethyl-5-methyl-N-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C22H26Cl2N4
  1
1
Ki = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374770
 Compound Info 
N,N-dibutyl-3-(2-chloro-4-methylphenyl)-2-ethyl-5-methylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C24H33ClN4
  1
1
Ki = 59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0944989
 Compound Info 
Butyl-[3-(2,4-dichloro-phenyl)-5-methyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-ethyl-amine
   Show/Hide
C19H22Cl2N4
  1
1
Ki = 60 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451360
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-5-methyl-2-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C24H32Cl2N4
  1
1
Ki = 64 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440477
 Compound Info 
N,N-dibutyl-3-(2-chloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C23H31ClN4O
  1
1
Ki = 70 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0404338
 Compound Info 
Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-b]pyridin-7-yl]-[2-(4-methoxy-phenyl)-ethyl]-amine
   Show/Hide
C27H30Cl2N4O
  1
1
Ki = 80 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527633
 Compound Info 
3-(4-chlorophenyl)-2,5-dimethyl-N,N-dipropylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C20H25ClN4
  1
1
Ki = 81.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0453212
 Compound Info 
N,N-dibutyl-3-(2,4-dichlorophenyl)-5-methyl-1-propylpyrazolo[4,3-b]pyridin-7-amine
   Show/Hide
C24H32Cl2N4
  1
1
Ki = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0487106
 Compound Info 
(2,5-Dimethyl-3-phenyl-2H-pyrazolo[4,3-b]pyridin-7-yl)-dipropyl-amine
   Show/Hide
C20H26N4
  1
1
Ki = 230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Kidney)
Cell Line Name Organism Disease
G-402
 Cell Line Info 
Homo sapiens (Human) Kidney neoplasm
A-498
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
786-O
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
SN12C
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
G-401
 Cell Line Info 
Homo sapiens (Human) Rhabdoid tumor of the kidney
AU-BEK
 Cell Line Info 
Bos taurus (Bovine) -
MDCK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-I
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-MDR1
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCKII-LE
 Cell Line Info 
Canis lupus familiaris (Dog) -
DK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK2/BCRP
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-Net6
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-UT-A1-AQP1-YFP
 Cell Line Info 
Canis lupus familiaris (Dog) -
CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-M6
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
OAT1-COS7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
BS-C-1
 Cell Line Info 
Chlorocebus pygerythrus (Vervet monkey) -
Vero
 Cell Line Info 
Chlorocebus sabaeus (Green monkey) -
OK
 Cell Line Info 
Didelphis virginiana (North American opossum) -
HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293T
 Cell Line Info 
Homo sapiens (Human) -
tsA201
 Cell Line Info 
Homo sapiens (Human) -
HEK293-A
 Cell Line Info 
Homo sapiens (Human) -
T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human) -
Expi293F
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293S
 Cell Line Info 
Homo sapiens (Human) -
HEK293-F
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA1-6E
 Cell Line Info 
Homo sapiens (Human) -
AD-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-H
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/17
 Cell Line Info 
Homo sapiens (Human) -
293T/ACE2 [Japan 2021]
 Cell Line Info 
Homo sapiens (Human) -
GripTite 293 MSR
 Cell Line Info 
Homo sapiens (Human) -
HL-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR8
 Cell Line Info 
Homo sapiens (Human) -
PathHunter HEK 293 EDG1 Total GPCR Internalization
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEKR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue IL-6
 Cell Line Info 
Homo sapiens (Human) -
HK-2 [Human kidney]
 Cell Line Info 
Homo sapiens (Human) -
HEK293-FT
 Cell Line Info 
Homo sapiens (Human) -
HEK-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR4
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue CD40L
 Cell Line Info 
Homo sapiens (Human) -
Expi293F GnTI-
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD1
 Cell Line Info 
Homo sapiens (Human) -
pEAK Rapid
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR9
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR7
 Cell Line Info 
Homo sapiens (Human) -
293Ta
 Cell Line Info 
Homo sapiens (Human) -
293-Dual hSTING-R232
 Cell Line Info 
Homo sapiens (Human) -
HEK293-CNG
 Cell Line Info 
Homo sapiens (Human) -
FreeStyle 293-F
 Cell Line Info 
Homo sapiens (Human) -
PrecisION hnAChR alpha7/ric3-HEK
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer ERbeta-UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
HEK385-7
 Cell Line Info 
Homo sapiens (Human) -
HEK2935
 Cell Line Info 
Homo sapiens (Human) -
ACTOne CXCR4
 Cell Line Info 
Homo sapiens (Human) -
HEK298
 Cell Line Info 
Homo sapiens (Human) -
293/GFP
 Cell Line Info 
Homo sapiens (Human) -
HEK293 AequoScreen
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue Null1-v
 Cell Line Info 
Homo sapiens (Human) -
HEK-GIRK-M4
 Cell Line Info 
Homo sapiens (Human) -
HTLA
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Galpha15
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-hH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-mH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
293AD
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/Galpha16-gustducin 44
 Cell Line Info 
Homo sapiens (Human) -
CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
NRK1-HEK293T
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SF-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-rH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-mH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-hH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SP-FLAG-hH3R-CRE-CBR
 Cell Line Info 
Homo sapiens (Human) -
293/AP1-luc
 Cell Line Info 
Homo sapiens (Human) -
293GT
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer AR-UAS-bla Griptite 293
 Cell Line Info 
Homo sapiens (Human) -
UAS-MR-bla HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-DR-GFP
 Cell Line Info 
Homo sapiens (Human) -
PSC-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293-A2B
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-rH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Hana3A
 Cell Line Info 
Homo sapiens (Human) -
HEK293S GnTI-
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293H
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
HEKMSR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-hNET
 Cell Line Info 
Homo sapiens (Human) -
HEK-hDAT
 Cell Line Info 
Homo sapiens (Human) -
HEK-hSERT
 Cell Line Info 
Homo sapiens (Human) -
EE-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-A2A
 Cell Line Info 
Homo sapiens (Human) -
HEK293EM
 Cell Line Info 
Homo sapiens (Human) -
293-NB2
 Cell Line Info 
Homo sapiens (Human) -
HEK-SEAP
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Gal4
 Cell Line Info 
Homo sapiens (Human) -
Octn2-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn1-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn3-HEK
 Cell Line Info 
Homo sapiens (Human) -
HEK293superTOP
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB1
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-qs5-HA
 Cell Line Info 
Homo sapiens (Human) -
EDG3-Ga15-bla HEK293T
 Cell Line Info 
Homo sapiens (Human) -
LLC-MK2
 Cell Line Info 
Macaca mulatta (Rhesus macaque) -
BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK-21 clone 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK570
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
TK-TS 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK/AC9
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
mIMCD-3
 Cell Line Info 
Mus musculus (Mouse) -
RK3E
 Cell Line Info 
Rattus norvegicus (Rat) -
KNRK
 Cell Line Info 
Rattus norvegicus (Rat) -
NRK-52E
 Cell Line Info 
Rattus norvegicus (Rat) -
SKPT-0193 Cl.2
 Cell Line Info 
Rattus norvegicus (Rat) -
RKE
 Cell Line Info 
Rattus norvegicus (Rat) -
LLC-PK1
 Cell Line Info 
Sus scrofa (Pig) -
LLC-GA5-CoL150
 Cell Line Info 
Sus scrofa (Pig) -
PK-15
 Cell Line Info 
Sus scrofa (Pig) -
HKRK-B28
 Cell Line Info 
Sus scrofa (Pig) -
PK15NTD
 Cell Line Info 
Sus scrofa (Pig) -