General Information of the Cell Line
Cell Line ID
CL000109
Cell Line Name
COS-1
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category
Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Tissue Information
Kidney
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01489, 3-oxo-5-alpha-steroid 4-dehydrogenase 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0345390
 Compound Info 
4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-amino]-benzoyl}-indol-1-yl)-butyric acid
   Show/Hide
C40H44N2O3
  1
1
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463696
 Compound Info 
4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-phenoxy}-butyric acid
   Show/Hide
C32H27NO5
  1
1
IC50 = 270 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463705
 Compound Info 
4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid
   Show/Hide
C32H25F2NO5
  1
1
IC50 = 340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463441
 Compound Info 
4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid
   Show/Hide
C34H31NO7
  1
1
IC50 = 930 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0476671
 Compound Info 
4-{2-[5-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-phenoxy}-butyric acid
   Show/Hide
C32H27NO5
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01430, 3-oxo-5-alpha-steroid 4-dehydrogenase 1
 Protein Info 
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
 Protein Info 
Protein ID: PT05210, Alkaline phosphatase, placental type
 Protein Info 
Protein ID: PT01329, Alkaline phosphatase, tissue-nonspecific isozyme
 Protein Info 
Protein ID: PT01089, Alpha-1A adrenergic receptor
 Protein Info 
Protein ID: PT01007, Alpha-1B adrenergic receptor
 Protein Info 
Protein ID: PT01004, Alpha-1D adrenergic receptor
 Protein Info 
Protein ID: PT01650, Alpha-2A adrenergic receptor
 Protein Info 
Protein ID: PT00894, Androgen receptor
 Protein Info 
Protein ID: PT01286, Bile acid receptor
 Protein Info 
Protein ID: PT01200, Delta-type opioid receptor
 Protein Info 
Protein ID: PT00886, Estrogen receptor
 Protein Info 
Protein ID: PT00889, Estrogen receptor beta
 Protein Info 
Protein ID: PT03879, Excitatory amino acid transporter 3
 Protein Info 
Protein ID: PT01091, Fibroblast growth factor receptor 1
 Protein Info 
Protein ID: PT06138, Glycogen synthase kinase-3 beta
 Protein Info 
Protein ID: PT03662, Intestinal-type alkaline phosphatase
 Protein Info 
Protein ID: PT06212, Intestinal-type alkaline phosphatase
 Protein Info 
Protein ID: PT00914, Melanocortin receptor 4
 Protein Info 
Protein ID: PT01154, Mineralocorticoid receptor
 Protein Info 
Protein ID: PT01056, Minibrain-related kinase
 Protein Info 
Protein ID: PT01515, Mu-type opioid receptor
 Protein Info 
Protein ID: PT01549, Mu-type opioid receptor
 Protein Info 
Protein ID: PT04406, Neuropeptide FF receptor 1
 Protein Info 
Protein ID: PT02666, Neuropeptide FF receptor 2
 Protein Info 
Protein ID: PT01795, Neuropeptide Y receptor type 5
 Protein Info 
Protein ID: PT03733, Nuclear receptor subfamily 1 group I member 3
 Protein Info 
Protein ID: PT01658, Oxytocin receptor
 Protein Info 
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
 Protein Info 
Protein ID: PT01919, Peroxisome proliferator-activated receptor alpha
 Protein Info 
Protein ID: PT00909, Peroxisome proliferator-activated receptor delta
 Protein Info 
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
 Protein Info 
Protein ID: PT05403, Prostaglandin E2 receptor EP1 subtype
 Protein Info 
Protein ID: PT04361, Protein smoothened
 Protein Info 
Protein ID: PT01930, Retinoic acid receptor RXR-alpha
 Protein Info 
Protein ID: PT01474, Retinoic acid receptor RXR-beta
 Protein Info 
Protein ID: PT02769, Retinoic acid receptor RXR-gamma
 Protein Info 
Protein ID: PT00884, Sodium-dependent dopamine transporter
 Protein Info 
Protein ID: PT01026, Sodium-dependent noradrenaline transporter
 Protein Info 
Protein ID: PT06283, Sodium-dependent proline transporter
 Protein Info 
Protein ID: PT00871, Sodium-dependent serotonin transporter
 Protein Info 
Protein ID: PT03804, Sodium/glucose cotransporter 1
 Protein Info 
Protein ID: PT02415, Sodium/glucose cotransporter 2
 Protein Info 
Protein ID: PT02378, Vitamin D3 receptor
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0054091
 Compound Info 
N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide
   Show/Hide
 C21H15F2N3O3S  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0278283
 Compound Info 
N-[[4-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
   Show/Hide
 C21H15F3N4O3S  1
1
IC50 = 501 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Kidney)
Cell Line Name Organism Disease
G-402
 Cell Line Info 
Homo sapiens (Human) Kidney neoplasm
A-498
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
786-O
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
SN12C
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
G-401
 Cell Line Info 
Homo sapiens (Human) Rhabdoid tumor of the kidney
AU-BEK
 Cell Line Info 
Bos taurus (Bovine) -
MDCK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-I
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-MDR1
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCKII-LE
 Cell Line Info 
Canis lupus familiaris (Dog) -
DK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK2/BCRP
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-Net6
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-UT-A1-AQP1-YFP
 Cell Line Info 
Canis lupus familiaris (Dog) -
CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-M6
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
OAT1-COS7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
BS-C-1
 Cell Line Info 
Chlorocebus pygerythrus (Vervet monkey) -
Vero
 Cell Line Info 
Chlorocebus sabaeus (Green monkey) -
OK
 Cell Line Info 
Didelphis virginiana (North American opossum) -
HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293T
 Cell Line Info 
Homo sapiens (Human) -
tsA201
 Cell Line Info 
Homo sapiens (Human) -
HEK293-A
 Cell Line Info 
Homo sapiens (Human) -
T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human) -
Expi293F
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293S
 Cell Line Info 
Homo sapiens (Human) -
HEK293-F
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA1-6E
 Cell Line Info 
Homo sapiens (Human) -
AD-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-H
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/17
 Cell Line Info 
Homo sapiens (Human) -
293T/ACE2 [Japan 2021]
 Cell Line Info 
Homo sapiens (Human) -
GripTite 293 MSR
 Cell Line Info 
Homo sapiens (Human) -
HL-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR8
 Cell Line Info 
Homo sapiens (Human) -
PathHunter HEK 293 EDG1 Total GPCR Internalization
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEKR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue IL-6
 Cell Line Info 
Homo sapiens (Human) -
HK-2 [Human kidney]
 Cell Line Info 
Homo sapiens (Human) -
HEK293-FT
 Cell Line Info 
Homo sapiens (Human) -
HEK-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR4
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue CD40L
 Cell Line Info 
Homo sapiens (Human) -
Expi293F GnTI-
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD1
 Cell Line Info 
Homo sapiens (Human) -
pEAK Rapid
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR9
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR7
 Cell Line Info 
Homo sapiens (Human) -
293Ta
 Cell Line Info 
Homo sapiens (Human) -
293-Dual hSTING-R232
 Cell Line Info 
Homo sapiens (Human) -
HEK293-CNG
 Cell Line Info 
Homo sapiens (Human) -
FreeStyle 293-F
 Cell Line Info 
Homo sapiens (Human) -
PrecisION hnAChR alpha7/ric3-HEK
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer ERbeta-UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
HEK385-7
 Cell Line Info 
Homo sapiens (Human) -
HEK2935
 Cell Line Info 
Homo sapiens (Human) -
ACTOne CXCR4
 Cell Line Info 
Homo sapiens (Human) -
HEK298
 Cell Line Info 
Homo sapiens (Human) -
HEK273
 Cell Line Info 
Homo sapiens (Human) -
293/GFP
 Cell Line Info 
Homo sapiens (Human) -
HEK293 AequoScreen
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue Null1-v
 Cell Line Info 
Homo sapiens (Human) -
HEK-GIRK-M4
 Cell Line Info 
Homo sapiens (Human) -
HTLA
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Galpha15
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-hH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-mH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
293AD
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/Galpha16-gustducin 44
 Cell Line Info 
Homo sapiens (Human) -
CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
NRK1-HEK293T
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SF-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-rH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-mH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-hH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SP-FLAG-hH3R-CRE-CBR
 Cell Line Info 
Homo sapiens (Human) -
293/AP1-luc
 Cell Line Info 
Homo sapiens (Human) -
293GT
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer AR-UAS-bla Griptite 293
 Cell Line Info 
Homo sapiens (Human) -
UAS-MR-bla HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-DR-GFP
 Cell Line Info 
Homo sapiens (Human) -
PSC-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293-A2B
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-rH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Hana3A
 Cell Line Info 
Homo sapiens (Human) -
HEK293S GnTI-
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293H
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
HEKMSR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-hNET
 Cell Line Info 
Homo sapiens (Human) -
HEK-hDAT
 Cell Line Info 
Homo sapiens (Human) -
HEK-hSERT
 Cell Line Info 
Homo sapiens (Human) -
EE-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-A2A
 Cell Line Info 
Homo sapiens (Human) -
HEK293EM
 Cell Line Info 
Homo sapiens (Human) -
293-NB2
 Cell Line Info 
Homo sapiens (Human) -
HEK-SEAP
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Gal4
 Cell Line Info 
Homo sapiens (Human) -
Octn2-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn1-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn3-HEK
 Cell Line Info 
Homo sapiens (Human) -
HEK293superTOP
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB1
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-qs5-HA
 Cell Line Info 
Homo sapiens (Human) -
EDG3-Ga15-bla HEK293T
 Cell Line Info 
Homo sapiens (Human) -
LLC-MK2
 Cell Line Info 
Macaca mulatta (Rhesus macaque) -
BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK-21 clone 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK570
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
TK-TS 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK/AC9
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
mIMCD-3
 Cell Line Info 
Mus musculus (Mouse) -
RK3E
 Cell Line Info 
Rattus norvegicus (Rat) -
KNRK
 Cell Line Info 
Rattus norvegicus (Rat) -
NRK-52E
 Cell Line Info 
Rattus norvegicus (Rat) -
SKPT-0193 Cl.2
 Cell Line Info 
Rattus norvegicus (Rat) -
RKE
 Cell Line Info 
Rattus norvegicus (Rat) -
LLC-PK1
 Cell Line Info 
Sus scrofa (Pig) -
LLC-GA5-CoL150
 Cell Line Info 
Sus scrofa (Pig) -
PK-15
 Cell Line Info 
Sus scrofa (Pig) -
HKRK-B28
 Cell Line Info 
Sus scrofa (Pig) -
PK15NTD
 Cell Line Info 
Sus scrofa (Pig) -