Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01430 , 3-oxo-5-alpha-steroid 4-dehydrogenase 1
 Protein Info 
Gene Name SRD5A1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P18405
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109
 Cell Line Info 
 Protein ID: PT01430
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0345390
 Compound Info 
4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-amino]-benzoyl}-indol-1-yl)-butyric acid
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C40H44N2O3
  1
1
IC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463705
 Compound Info 
4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid
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C32H25F2NO5
  1
1
IC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463696
 Compound Info 
4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-phenoxy}-butyric acid
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C32H27NO5
  1
1
IC50 = 62 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463441
 Compound Info 
4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid
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C34H31NO7
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0476671
 Compound Info 
4-{2-[5-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-phenoxy}-butyric acid
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C32H27NO5
  1
1
IC50 = 310 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS