Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT00910 , Peroxisome proliferator-activated receptor alpha
Gene Name PPARA
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q07869
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109  Protein ID: PT00910
 
Compound ID Compound Name Compound Formula
CP0034717
(S)-2-(4-(3-(2-chloro-4-cyclohexylphenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C27H35ClO4
 1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0034731
(S)-2-(4-(3-(2-chloro-4-(2,2,2-trifluoroethyl)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C23H26ClF3O4
 1
1
EC50 < 1 nM
   TI
   LI
   LO
   TS
CP0078110
2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-propoxy]-phenoxy}-propionic acid
   Show/Hide
C28H29NO6
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0207654
2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenyl}-propionic acid
   Show/Hide
C30H33NO5
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0208054
2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenoxy}-propionic acid
   Show/Hide
C30H33NO6
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0045073
(R)-7-[3-(2-Chloro-4-cyclohexyl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C26H31ClO5
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0174902
(2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}isobutyric Acid
   Show/Hide
C29H25ClF3NO5
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0104589
(S)-2-(4-(3-(2-chloro-4-(trifluoromethoxy)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C22H24ClF3O5
 1
1
EC50 = 2.1 nM
   TI
   LI
   LO
   TS
CP0077693
2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C27H28ClFO5
 1
1
EC50 = 2.5 nM
   TI
   LI
   LO
   TS
CP0077696
2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)benzyl)-2-ethylbutanoic acid
   Show/Hide
C28H30ClFO5
 1
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
CP0034710
(S)-2-(4-(3-(2-chloro-4-(trifluoromethyl)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C22H24ClF3O4
 1
1
EC50 = 2.9 nM
   TI
   LI
   LO
   TS
CP0130403
2-[3-chloro-4-[3-[(3-phenyl-7-propyl-1,2-benzoxazol-6-yl)oxy]propylsulfanyl]phenyl]acetic acid
   Show/Hide
C27H26ClNO4S
 1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CP0213824
2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy)propoxy)phenyl)acetic acid
   Show/Hide
C27H27NO5
 1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CP0324132
4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-propoxy]-phenyl}-butyric acid
   Show/Hide
C29H31NO5
 1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CP0302910
(R)-2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C27H28ClFO5
 1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CP0178891
2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenyl}-propionic acid
   Show/Hide
C31H35NO5
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0220490
2-[4-[3-[(3-phenyl-7-propyl-1,2-benzoxazol-6-yl)oxy]propoxy]phenoxy]acetic acid
   Show/Hide
C27H27NO6
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0160927
(R)-7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C23H24ClF3O6
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0225228
(R)-7-{3-[2-Chloro-4-(1,1-dimethyl-propyl)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C25H31ClO5
 1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
CP0155637
(3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)oxy]butoxy}phenyl)acetic acid
   Show/Hide
C28H29NO5
 1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
CP0111376
(R)-7-[3-(2-Chloro-4-cyclohexyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C27H33ClO5
 1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
CP0046923
(R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C22H22ClF3O6
 1
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
CP0051867
(R)-7-[3-(2-Chloro-4-isobutyl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C24H29ClO5
 1
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
CP0080418
(R)-7-[3-(2-Chloro-4-isobutyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C25H31ClO5
 1
1
EC50 = 7 nM
   TI
   LI
   LO
   TS
CP0795528
(S)-2-((4-(3-(6-chloro-2,2-dimethyl-4-(trifluoromethyl)-2H-chromen-7-yloxy)propoxy)phenyl)methyl)-2-methylbutanoic acid
   Show/Hide
C26H28ClF3O5
 1
1
EC50 = 7.3 nM
   TI
   LI
   LO
   TS
CP0090225
(S)-2-(4-(3-(2-chloro-4-(2,2,2-trifluoroethoxy)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C23H26ClF3O5
 1
1
EC50 = 7.8 nM
   TI
   LI
   LO
   TS
CP0208053
2-[4-[4-[(3-phenyl-7-propyl-1,2-benzoxazol-6-yl)oxy]butoxy]phenyl]acetic acid
   Show/Hide
C28H29NO5
 1
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
CP0208071
3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-benzoic acid
   Show/Hide
C27H27NO5
 1
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
CP0334515
(R)-7-[3-(2-Chloro-4-cyclopentyl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C25H29ClO5
 1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
CP0101367
2-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenoxy}-propionic acid
   Show/Hide
C29H31NO6
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0159826
(S)-2-methyl-2-((4-(3-(8-methyl-2-oxo-4-(trifluoromethyl)-2H-chromen-7-yloxy)propoxy)phenyl)methyl)butanoic acid
   Show/Hide
C26H27F3O6
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0222410
(S)-2-((4-(3-(2,2-dimethyl-4-(3-(trifluoromethyl)phenyl)-2H-chromen-7-yloxy)propoxy)phenyl)methyl)-2-methylbutanoic acid
   Show/Hide
C33H35F3O5
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0170631
(S)-2-(4-(3-(2-chloro-4-(methylsulfonyloxy)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C22H27ClO7S
 1
1
EC50 = 11.4 nM
   TI
   LI
   LO
   TS
CP0100328
(E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenyl}-acrylic acid
   Show/Hide
C29H29NO5
 1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
CP0034712
3-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)phenyl)-2-cyclobutylpropanoic acid
   Show/Hide
C28H28ClFO5
 1
1
EC50 = 15 nM
   TI
   LI
   LO
   TS
CP0077688
2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)phenoxy)-2-methylpropanoic acid
   Show/Hide
C25H24ClFO6
 1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CP0170629
(S)-2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C27H28ClFO5
 1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CP0149819
(R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C21H20ClF3O6
 1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CP0034705
2-(3-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)phenoxy)-2-methylpropanoic acid
   Show/Hide
C25H24ClFO6
 1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CP0290865
(R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C26H31ClO6
 1
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
CP0281023
(R)-7-[3-(2-Chloro-4-isopropyl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C23H27ClO5
 1
1
EC50 = 23 nM
   TI
   LI
   LO
   TS
CP0152971
(R)-7-[3-(2-Chloro-4-isopropyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C24H29ClO5
 1
1
EC50 = 24 nM
   TI
   LI
   LO
   TS
CP0104587
(S)-2-(4-(3-(2-chloro-4-(4,4-dimethylcyclohexyl)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C29H39ClO4
 1
1
EC50 = 27.5 nM
   TI
   LI
   LO
   TS
CP0152968
(R)-7-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C25H31ClO5
 1
1
EC50 = 28 nM
   TI
   LI
   LO
   TS
CP0467414
(2E,4E,8Z,11Z,14Z,17Z)-icosa-2,4,8,11,14,17-hexaenoic acid
   Show/Hide
C20H28O2
 1
1
EC50 = 32 nM
   TI
   LI
   LO
   TS
CP0131262
4-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-ethoxy]-phenyl}-butyric acid
   Show/Hide
C28H29NO5
 1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
CP0159874
2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butoxy)phenoxy)-2-methylpropanoic acid
   Show/Hide
C26H26ClFO6
 1
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
CP0048558
(R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C22H22ClF3O5
 1
1
EC50 = 36 nM
   TI
   LI
   LO
   TS
CP0038450
(R)-7-{3-[2-Chloro-4-(4-fluoro-phenoxy)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C27H26ClFO6
 1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0080381
(R)-7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C22H22ClF3O6
 1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0111592
(R)-7-[3-(2-Chloro-4-isopropoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C23H27ClO6
 1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0159827
(S)-2-((4-(3-(6-chloro-2-oxo-4-(trifluoromethyl)-2H-chromen-7-yloxy)propoxy)phenyl)methyl)-2-methylbutanoic acid
   Show/Hide
C25H24ClF3O6
 1
1
EC50 = 44 nM
   TI
   LI
   LO
   TS
CP0257979
2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenyl}-propionic acid
   Show/Hide
C30H33NO5
 1
1
EC50 = 50 nM
   TI
   LI
   LO
   TS
CP0200400
2-(4-(3-(4-(4-fluorophenoxy)-2-propylphenoxy)propoxy)phenoxy)-2-methylpropanoic acid
   Show/Hide
C28H31FO6
 1
1
EC50 = 51 nM
   TI
   LI
   LO
   TS
CP0088604
3-Methyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenyl}-butyric acid
   Show/Hide
C31H35NO5
 1
1
EC50 = 53 nM
   TI
   LI
   LO
   TS
CP0215321
(S)-2-(4-(3-(2-chlorophenoxy)propoxy)benzyl)-2-methylbutanoic acid
   Show/Hide
C21H25ClO4
 1
1
EC50 = 54.1 nM
   TI
   LI
   LO
   TS
CP0180190
(R)-7-{3-[2-Chloro-4-(4-fluoro-phenoxy)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C26H24ClFO6
 1
1
EC50 = 61 nM
   TI
   LI
   LO
   TS
CP0170624
2-(4-(2-(2-chloro-4-(4-fluorophenoxy)phenoxy)ethoxy)phenoxy)-2-methylpropanoic acid
   Show/Hide
C24H22ClFO6
 1
1
EC50 = 62 nM
   TI
   LI
   LO
   TS
CP0646515
5-(3-{3-[4-(4-Fluoro-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C27H26FNO5S
 1
1
EC50 = 66 nM
   TI
   LI
   LO
   TS
CP0152913
(R)-7-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C24H29ClO5
 1
1
EC50 = 80 nM
   TI
   LI
   LO
   TS
CP0708518
5-(3-(3-(4-(3,4-dichlorophenoxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C27H25Cl2NO5S
 1
1
EC50 = 82 nM
   TI
   LI
   LO
   TS
CP0672411
5-(3-{3-[4-(4-Fluoro-3-methyl-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C28H28FNO5S
 1
1
EC50 = 85 nM
   TI
   LI
   LO
   TS
CP0220876
2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenoxy}-propionic acid
   Show/Hide
C30H33NO6
 1
1
EC50 = 92 nM
   TI
   LI
   LO
   TS
CP0786452
(S)-2-[(2E,4E)-5-Methylhexadienoyl]-7-(2-{5-methyl-2-[(1E)-5-methylhexen-1-yl]oxazol-4-yl}ethoxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid tert-butylamine salt
   Show/Hide
C34H49N3O5
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0277228
7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-chroman-2-carboxylic acid
   Show/Hide
C21H20ClF3O6
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0040986
(R)-7-[3-(2,4-Dichloro-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C21H22Cl2O5
 1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CP0184722
(R)-7-[3-(2-Chloro-4-cyclobutylmethoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C25H29ClO6
 1
1
EC50 = 140 nM
   TI
   LI
   LO
   TS
CP0654731
5-(3-{3-[4-(4-Chloro-3-methyl-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C28H28ClNO5S
 1
1
EC50 = 156 nM
   TI
   LI
   LO
   TS
CP0686397
5-(3-{3-[4-(4-Chloro-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C27H26ClNO5S
 1
1
EC50 = 180 nM
   TI
   LI
   LO
   TS
CP0174901
1-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}-1-cyclobutanecarboxylic Acid
   Show/Hide
C29H23ClF3NO5
 1
1
EC50 = 185 nM
   TI
   LI
   LO
   TS
CP0046903
(R)-7-[3-(2-Chloro-4-ethoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C22H25ClO6
 1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
CP0043911
(2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}butanoic Acid
   Show/Hide
C28H23ClF3NO5
 1
1
EC50 = 230 nM
   TI
   LI
   LO
   TS
CP0045113
(R)-7-[3-(2-Chloro-4-cyclopropylmethoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C24H27ClO6
 1
1
EC50 = 240 nM
   TI
   LI
   LO
   TS
CP0787014
(S)-2-[(2E,4E)-Hexadienoyl]-7-(2-{5-methyl-2-{[(1E)-4-methylpenten-1-yl]oxazol-4-yl}ethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid tert-butylamine salt
   Show/Hide
C32H45N3O5
 1
1
EC50 = 240 nM
   TI
   LI
   LO
   TS
CP0036283
2-[3-[4-[(3-phenyl-7-propyl-1,2-benzoxazol-6-yl)oxy]butoxy]phenoxy]acetic acid
   Show/Hide
C28H29NO6
 1
1
EC50 = 248 nM
   TI
   LI
   LO
   TS
CP0083171
(R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C29H35ClO5
 1
1
EC50 = 300 nM
   TI
   LI
   LO
   TS
CP0778411
(S)-2-[(2E,4E)-Hexadienoyl]-7-(5-methyl-2-{2-[(1E)-3-methylbuten-1-yl]oxazol-4-yl}ethoxy)-1,2,3,4-tetrahydroisoqunoline-3-carboxylic acid tert-butylamine salt
   Show/Hide
C31H43N3O5
 1
1
EC50 = 300 nM
   TI
   LI
   LO
   TS
CP0070863
(2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy]propanoicAcid
   Show/Hide
C27H21ClF3NO5
 1
1
EC50 = 320 nM
   TI
   LI
   LO
   TS
CP0108856
(2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}isobutyric Acid
   Show/Hide
C29H25ClF3NO5
 1
1
EC50 = 370 nM
   TI
   LI
   LO
   TS
CP0108857
(2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}pentanoic Acid
   Show/Hide
C29H25ClF3NO5
 1
1
EC50 = 380 nM
   TI
   LI
   LO
   TS
CP0082083
(R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C28H33ClO5
 1
1
EC50 = 420 nM
   TI
   LI
   LO
   TS
CP0186194
3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-butoxy]-phenyl}-propionic acid
   Show/Hide
C29H31NO5
 1
1
EC50 = 429 nM
   TI
   LI
   LO
   TS
CP0170630
2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)benzyl)pentanoic acid
   Show/Hide
C27H28ClFO5
 1
1
EC50 = 454 nM
   TI
   LI
   LO
   TS
CP0048728
(2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}butanoic Acid
   Show/Hide
C28H23ClF3NO5
 1
1
EC50 = 500 nM
   TI
   LI
   LO
   TS
CP0499556
2-fluoro-2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid
   Show/Hide
C21H17F4NO3S2
 1
1
EC50 = 560 nM
   TI
   LI
   LO
   TS
CP0080583
(R)-7-{3-[2-Chloro-4-(4,4-dimethyl-cyclohexyl)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
   Show/Hide
C29H37ClO5
 1
1
EC50 = 700 nM
   TI
   LI
   LO
   TS
CP0467415
2-[2-ethyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]-2-fluoroacetic acid
   Show/Hide
C22H19F4NO3S2
 1
1
EC50 = 710 nM
   TI
   LI
   LO
   TS
CP0524690
2-fluoro-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]-2-propan-2-ylphenoxy]acetic acid
   Show/Hide
C23H21F4NO3S2
 1
1
EC50 = 735 nM
   TI
   LI
   LO
   TS
CP0149897
(R)-7-{3-[2-Chloro-4-(4,4-dimethyl-cyclohexyl)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid
   Show/Hide
C28H35ClO5
 1
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0380855
2-(3-(3-(2-(4-methylbenzoyl)-1H-pyrrol-1-yl)prop-1-enyl)phenoxy)acetic acid
   Show/Hide
C23H21NO4
 1
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0076778
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
   Show/Hide
C20H21ClO4
 1
1
EC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0672440
5-(4-(3-(4-(4-chlorophenoxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C27H26ClNO5S
 1
1
EC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0412240
2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-1-enyl)phenoxy)acetic acid
   Show/Hide
C23H21NO5
 1
1
EC50 = 3700 nM
   TI
   LI
   LO
   TS
CP0259373
(2S)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy]propanoicAcid
   Show/Hide
C27H21ClF3NO5
 1
1
EC50 = 4890 nM
   TI
   LI
   LO
   TS
CP0658355
5-(4-(3-(4-(4-methoxyphenoxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C28H29NO6S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0077280
3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-propan-2-yloxypyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C22H29ClF3N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0166769
(E)-3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-propan-2-yloxypyrazol-3-yl]-N-pentylsulfonylprop-2-enamide
   Show/Hide
C22H27ClF3N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0166771
(E)-3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-cyclopropylpyrazol-3-yl]-N-pentylsulfonylprop-2-enamide
   Show/Hide
C22H25ClF3N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0199273
(E)-3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-propan-2-yloxypyrazol-3-yl]-N-(3-methylbutylsulfonyl)prop-2-enamide
   Show/Hide
C22H27ClF3N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0391833
3-[5-butoxy-2-[(2,4-dichlorophenyl)methyl]pyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C22H31Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0391834
(E)-3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-ylpyrazol-3-yl]-N-pentylsulfonylprop-2-enamide
   Show/Hide
C21H27Cl2N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0399018
3-[2-[(2,4-dichlorophenyl)methyl]-5-(2-methoxyethoxy)pyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C21H29Cl2N3O5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0416987
(E)-3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-yloxypyrazol-3-yl]-N-pentylsulfonylprop-2-enamide
   Show/Hide
C21H27Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0419494
3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-yloxypyrazol-3-yl]-N-(3-methylbutylsulfonyl)propanamide
   Show/Hide
C21H29Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0439370
3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-cyclopropylpyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C22H27ClF3N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0457462
N-(benzenesulfonyl)-3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-yloxypyrazol-3-yl]propanamide
   Show/Hide
C22H23Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0484754
3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-propan-2-ylpyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C22H29ClF3N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0484758
3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-yloxypyrazol-3-yl]-N-hexylsulfonylpropanamide
   Show/Hide
C22H31Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0484803
3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-ylpyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C21H29Cl2N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0490359
3-[2-[(2,4-dichlorophenyl)methyl]-5-phenylpyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C24H27Cl2N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0490361
N-butylsulfonyl-3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-yloxypyrazol-3-yl]propanamide
   Show/Hide
C20H27Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0495428
N-cyclohexylsulfonyl-3-[2-[(2,4-dichlorophenyl)methyl]-5-propan-2-yloxypyrazol-3-yl]propanamide
   Show/Hide
C22H29Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0496240
3-[2-[(2,4-dichlorophenyl)methyl]-5-phenylmethoxypyrazol-3-yl]-N-pentylsulfonylpropanamide
   Show/Hide
C25H29Cl2N3O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0504039
(E)-3-[2-[[2-chloro-4-(trifluoromethyl)phenyl]methyl]-5-(2-methoxyethoxy)pyrazol-3-yl]-N-(3-methylbutylsulfonyl)prop-2-enamide
   Show/Hide
C22H27ClF3N3O5S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0879880
3-[1-(2,4-Dichlorobenzyl)-3-(pyridin-2-ylmethoxy)-1H-pyrazol-5-yl]-N-(pentylsulfonyl)propanamide hydrochloride
   Show/Hide
C24H29Cl3N4O4S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0314944
(E)-3-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy-4-(2-methoxyethoxy)phenyl]-N-pentylsulfonylprop-2-enamide
   Show/Hide
C23H26ClF3N2O6S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0042877
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic acid
   Show/Hide
C17H15ClO4
 1
1
EC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0444887
(E)-9-oxohexadec-7-enoic acid
   Show/Hide
C16H28O3
 1
1
EC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0412238
2-(3-(3-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)prop-1-enyl)phenyl)acetic acid
   Show/Hide
C23H21NO4
 1
1
EC50 = 21000 nM
   TI
   LI
   LO
   TS
CP0412944
(E)-9-oxohexadec-10-enoic acid
   Show/Hide
C16H28O3
 1
1
EC50 = 26000 nM
   TI
   LI
   LO
   TS
CP0053164
1-HEXYLDECANOIC ACID
   Show/Hide
C16H32O2
 1
1
EC50 = 35000 nM
   TI
   LI
   LO
   TS
CP0012720
2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid
   Show/Hide
C14H14ClN3O2S
 1
1
EC50 = 39000 nM
   TI
   LI
   LO
   TS
CP0645378
5-(4-(3-(4-(4-fluorophenoxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C27H26FNO5S
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0427644
5-chloro-2-(3-(2-(4-methoxybenzoyl)-4-methyl-1H-pyrrol-1-yl)prop-1-enyl)-N-(methylsulfonyl)benzamide
   Show/Hide
C24H23ClN2O5S
 1
1
EC50 > 90000 nM
   TI
   LI
   LO
   TS
CP0005387
Avandamet
   Show/Hide
C18H19N3O3S
 2
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
2
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0039118
2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic acid
   Show/Hide
C21H18F3NO3S2
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0654439
5-(3-{3-[4-(4-Methoxy-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C28H29NO6S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0661032
5-(3-{3-[4-(4-Hydroxy-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C27H27NO6S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0672145
5-(3-{3-[4-(4-Cyclopentyl-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C32H35NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0727828
5-(3-{3-[4-(Biphenyl-4-yloxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C33H31NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0782507
5-(3-{3-[4-(4-Isopropyl-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione
   Show/Hide
C30H33NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0654730
5-(4-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C27H27NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0677669
5-(3-methoxy-4-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C28H29NO6S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0679717
5-(4-(3-(4-(biphenyl-4-yloxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C33H31NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0680900
5-(3-methyl-4-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C28H29NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0684997
5-(3-chloro-4-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C27H26ClNO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0705705
5-(4-(3-(4-(4-isobutylphenoxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C31H35NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0716559
N-(4-(4-(3-(4-(2,4-dioxothiazolidin-5-yl)phenoxy)propoxy)-3-propylphenoxy)phenyl)-4-methylbenzenesulfonamide
   Show/Hide
C34H34N2O7S2
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0734398
5-(4-(3-(4-phenoxy-2-propylphenoxy)propoxy)-3-propylphenyl)thiazolidine-2,4-dione
   Show/Hide
C30H33NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0761598
5-(4-(4-(4-phenoxy-2-propylphenoxy)butoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C28H29NO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0761841
5-(4-(3-(4-(4-(methylsulfonyl)phenoxy)-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C28H29NO7S2
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0783387
5-(3-fluoro-4-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)thiazolidine-2,4-dione
   Show/Hide
C27H26FNO5S
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0282604
(2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}pentanoic Acid
   Show/Hide
C29H25ClF3NO5
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0293295
2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1Hindol-1-yl]methyl]phenoxy]acetic Acid
   Show/Hide
C26H19ClF3NO5
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0316148
2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl)methyl)phenoxy)acetic acid
   Show/Hide
C26H19ClF3NO5
 1
1
EC50 > 3000 nM
   TI
   LI
   LO
   TS