Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT02378 , Vitamin D3 receptor
 Protein Info 
Gene Name VDR
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P11473
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109
 Cell Line Info 
 Protein ID: PT02378
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0003145
 Compound Info 
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
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C27H44O3
  1
1
IC50 = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552250
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(4,4-dimethylpent-2-ynyloxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C29H44O3
  1
1
IC50 = 47 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523217
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(benzyloxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C29H40O3
  1
1
IC50 = 63 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426994
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(3,3-dimethyl-2-methylenebutoxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C29H46O3
  1
1
IC50 = 85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523218
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-7a-methyl-1-((S)-1-(2-(1-methylcyclohexyl)allyloxy)propan-2-yl)-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C32H50O3
  1
1
IC50 = 198 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528403
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(2-(6,6-dimethylcyclohex-1-enyl)allyloxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C33H50O3
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS