General Information of the Cell Line
Cell Line ID
CL000307
Cell Line Name
SN12C
Synonyms
SN-12C
SN12 C
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1705
Tissue Information
Kidney
Disease
Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02105, Mitogen-activated protein kinase 7
 Protein Info 
Compound ID Compound Name Compound Formula
CP0436072
 Compound Info 
2-[2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5-methyl-11-methylsulfonylpyrimido[4,5-b][1,4]benzodiazepin-6-one
   Show/Hide
C32H40N8O5S
  1
1
IC50 = 86 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0024313
 Compound Info 
[2-amino-4-(trifluoromethoxy)phenyl]-[4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]methanone
   Show/Hide
C25H28F3N7O2
  1
1
IC50 = 115 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521323
 Compound Info 
[4-(7-morpholin-4-ylpyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C24H24F3N5O3
  1
1
IC50 = 150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523267
 Compound Info 
[2-amino-4-(trifluoromethoxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone
   Show/Hide
C22H21F3N4O3
  1
1
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0534714
 Compound Info 
[4-[7-(3-hydroxy-3-methylpyrrolidin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C25H26F3N5O3
  1
1
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575467
 Compound Info 
[4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C25H27F3N6O2
  1
1
IC50 = 290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0436071
 Compound Info 
[3-amino-4-(trifluoromethoxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone
   Show/Hide
C22H21F3N4O3
  1
1
IC50 = 360 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577138
 Compound Info 
[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C22H20F3N3O3
  1
1
IC50 = 420 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558071
 Compound Info 
[4-(7-methoxypyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C21H19F3N4O3
  1
1
IC50 = 540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555155
 Compound Info 
[4-[7-[3-(dimethylamino)pyrrolidin-1-yl]pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C26H29F3N6O2
  1
1
IC50 = 670 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523154
 Compound Info 
[4-(7-methoxyquinolin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C23H21F3N2O3
  1
1
IC50 = 710 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0534712
 Compound Info 
[4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-(4-propan-2-yloxyphenyl)methanone
   Show/Hide
C25H29N3O4
  1
1
IC50 = 3750 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0469340
 Compound Info 
[4-(6-methoxyquinazolin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C22H20F3N3O3
  1
1
IC50 = 4100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0561935
 Compound Info 
[4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-[6-(trifluoromethoxy)pyridin-3-yl]methanone
   Show/Hide
C22H21F3N4O4
  1
1
IC50 = 7640 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552701
 Compound Info 
[4-(6-methoxypyrido[3,4-d]pyrimidin-4-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C21H19F3N4O3
  1
1
IC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0030297
 Compound Info 
[2-amino-4-(trifluoromethoxy)phenyl]-[4-[2-methyl-7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl]methanone
   Show/Hide
C26H30F3N7O2
  1
1
IC50 = 11000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0538081
 Compound Info 
[4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-(4-methylphenyl)methanone
   Show/Hide
C23H25N3O3
  1
1
IC50 = 11500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523155
 Compound Info 
[4-(6-methoxyisoquinolin-1-yl)piperidin-1-yl]-[4-(trifluoromethoxy)phenyl]methanone
   Show/Hide
C23H21F3N2O3
  1
1
IC50 = 29000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0006369
 Compound Info 
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
   Show/Hide
 C32H31N5O3  1
1
GI50 = 8470 nM
   TI
   LI
   LO
   TS
CP0007711
 Compound Info 
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
   Show/Hide
 C26H31F3N4O3  1
1
LC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0047056
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-N-dodecyl-2-hydroxy-benzamide
   Show/Hide
 C26H38N2O4  1
1
GI50 = 2600 nM
   TI
   LI
   LO
   TS
CP0062042
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(2-pyridin-2-yl-ethyl)-benzamide
   Show/Hide
 C21H21N3O4  1
1
GI50 = 19000 nM
   TI
   LI
   LO
   TS
CP0082019
 Compound Info 
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
   Show/Hide
 C22H21NO2S  1
1
GI50 = 3160 nM
   TI
   LI
   LO
   TS
CP0086475
 Compound Info 
2-[(4-methoxyphenyl)-diphenylmethyl]sulfanylethanamine
   Show/Hide
 C22H23NOS  1
1
GI50 = 130 nM
   TI
   LI
   LO
   TS
CP0091315
 Compound Info 
US9422297, AAG145-136
   Show/Hide
 C17H13ClN4  1
1
GI50 = 189 nM
   TI
   LI
   LO
   TS
CP0178481
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(2-morpholin-4-yl-ethyl)-benzamide
   Show/Hide
 C20H25N3O5  1
1
GI50 = 22000 nM
   TI
   LI
   LO
   TS
CP0194921
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-[2-(4-methoxy-phenyl)-ethyl]-benzamide
   Show/Hide
 C23H24N2O5  1
1
GI50 = 72000 nM
   TI
   LI
   LO
   TS
CP0212776
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-phenethyl-benzamide
   Show/Hide
 C22H22N2O4  1
1
GI50 = 18000 nM
   TI
   LI
   LO
   TS
CP0320349
 Compound Info 
N-benzyl-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C21H20N2O4  1
1
GI50 = 12000 nM
   TI
   LI
   LO
   TS
CP0337077
 Compound Info 
4-(2,5-Dihydroxy-benzylamino)-N-(3-phenyl-propyl)-benzamide
   Show/Hide
 C23H24N2O3  1
1
GI50 = 3200 nM
   TI
   LI
   LO
   TS
CP0358636
 Compound Info 
N-[2-(4-chlorophenyl)ethyl]-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C22H21ClN2O4  1
1
GI50 = 9800 nM
   TI
   LI
   LO
   TS
CP0370065
 Compound Info 
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
   Show/Hide
 C17H12ClN3OS  1
1
LC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
GI50 = 56.7 nM
   TI
   LI
   LO
   TS
CP0425261
 Compound Info 
N-(1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H15N3O2  1
1
GI50 = 611 nM
   TI
   LI
   LO
   TS
CP0426689
 Compound Info 
(2,6-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-(4-methoxyphenyl)-methylazanium;chloride
   Show/Hide
 C17H22ClN3O  1
1
GI50 = 31.8 nM
   TI
   LI
   LO
   TS
CP0465282
 Compound Info 
4-N-(4-methoxyphenyl)-4-N-methyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
 C18H17N5O  1
1
GI50 = 80.1 nM
   TI
   LI
   LO
   TS
CP0492215
 Compound Info 
N-benzyl-4-[(2,5-dihydroxyphenyl)methylamino]benzamide
   Show/Hide
 C21H20N2O3  1
1
GI50 = 9700 nM
   TI
   LI
   LO
   TS
CP0906523
 Compound Info 
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
   Show/Hide
 C23H25ClN4O  1
1
GI50 = 88.7 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Kidney)
Cell Line Name Organism Disease
G-402
 Cell Line Info 
Homo sapiens (Human) Kidney neoplasm
A-498
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
786-O
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
G-401
 Cell Line Info 
Homo sapiens (Human) Rhabdoid tumor of the kidney
AU-BEK
 Cell Line Info 
Bos taurus (Bovine) -
MDCK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-I
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-MDR1
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCKII-LE
 Cell Line Info 
Canis lupus familiaris (Dog) -
DK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK2/BCRP
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-Net6
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-UT-A1-AQP1-YFP
 Cell Line Info 
Canis lupus familiaris (Dog) -
CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-M6
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
OAT1-COS7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
BS-C-1
 Cell Line Info 
Chlorocebus pygerythrus (Vervet monkey) -
Vero
 Cell Line Info 
Chlorocebus sabaeus (Green monkey) -
OK
 Cell Line Info 
Didelphis virginiana (North American opossum) -
HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293T
 Cell Line Info 
Homo sapiens (Human) -
tsA201
 Cell Line Info 
Homo sapiens (Human) -
HEK293-A
 Cell Line Info 
Homo sapiens (Human) -
T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human) -
Expi293F
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293S
 Cell Line Info 
Homo sapiens (Human) -
HEK293-F
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA1-6E
 Cell Line Info 
Homo sapiens (Human) -
AD-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-H
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/17
 Cell Line Info 
Homo sapiens (Human) -
293T/ACE2 [Japan 2021]
 Cell Line Info 
Homo sapiens (Human) -
GripTite 293 MSR
 Cell Line Info 
Homo sapiens (Human) -
HL-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR8
 Cell Line Info 
Homo sapiens (Human) -
PathHunter HEK 293 EDG1 Total GPCR Internalization
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEKR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue IL-6
 Cell Line Info 
Homo sapiens (Human) -
HK-2 [Human kidney]
 Cell Line Info 
Homo sapiens (Human) -
HEK293-FT
 Cell Line Info 
Homo sapiens (Human) -
HEK-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR4
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue CD40L
 Cell Line Info 
Homo sapiens (Human) -
Expi293F GnTI-
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD1
 Cell Line Info 
Homo sapiens (Human) -
pEAK Rapid
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR9
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR7
 Cell Line Info 
Homo sapiens (Human) -
293Ta
 Cell Line Info 
Homo sapiens (Human) -
293-Dual hSTING-R232
 Cell Line Info 
Homo sapiens (Human) -
HEK293-CNG
 Cell Line Info 
Homo sapiens (Human) -
FreeStyle 293-F
 Cell Line Info 
Homo sapiens (Human) -
PrecisION hnAChR alpha7/ric3-HEK
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer ERbeta-UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
HEK385-7
 Cell Line Info 
Homo sapiens (Human) -
HEK2935
 Cell Line Info 
Homo sapiens (Human) -
ACTOne CXCR4
 Cell Line Info 
Homo sapiens (Human) -
HEK298
 Cell Line Info 
Homo sapiens (Human) -
HEK273
 Cell Line Info 
Homo sapiens (Human) -
293/GFP
 Cell Line Info 
Homo sapiens (Human) -
HEK293 AequoScreen
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue Null1-v
 Cell Line Info 
Homo sapiens (Human) -
HEK-GIRK-M4
 Cell Line Info 
Homo sapiens (Human) -
HTLA
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Galpha15
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-hH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-mH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
293AD
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/Galpha16-gustducin 44
 Cell Line Info 
Homo sapiens (Human) -
CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
NRK1-HEK293T
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SF-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-rH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-mH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-hH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SP-FLAG-hH3R-CRE-CBR
 Cell Line Info 
Homo sapiens (Human) -
293/AP1-luc
 Cell Line Info 
Homo sapiens (Human) -
293GT
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer AR-UAS-bla Griptite 293
 Cell Line Info 
Homo sapiens (Human) -
UAS-MR-bla HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-DR-GFP
 Cell Line Info 
Homo sapiens (Human) -
PSC-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293-A2B
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-rH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Hana3A
 Cell Line Info 
Homo sapiens (Human) -
HEK293S GnTI-
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293H
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
HEKMSR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-hNET
 Cell Line Info 
Homo sapiens (Human) -
HEK-hDAT
 Cell Line Info 
Homo sapiens (Human) -
HEK-hSERT
 Cell Line Info 
Homo sapiens (Human) -
EE-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-A2A
 Cell Line Info 
Homo sapiens (Human) -
HEK293EM
 Cell Line Info 
Homo sapiens (Human) -
293-NB2
 Cell Line Info 
Homo sapiens (Human) -
HEK-SEAP
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Gal4
 Cell Line Info 
Homo sapiens (Human) -
Octn2-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn1-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn3-HEK
 Cell Line Info 
Homo sapiens (Human) -
HEK293superTOP
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB1
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-qs5-HA
 Cell Line Info 
Homo sapiens (Human) -
EDG3-Ga15-bla HEK293T
 Cell Line Info 
Homo sapiens (Human) -
LLC-MK2
 Cell Line Info 
Macaca mulatta (Rhesus macaque) -
BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK-21 clone 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK570
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
TK-TS 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK/AC9
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
mIMCD-3
 Cell Line Info 
Mus musculus (Mouse) -
RK3E
 Cell Line Info 
Rattus norvegicus (Rat) -
KNRK
 Cell Line Info 
Rattus norvegicus (Rat) -
NRK-52E
 Cell Line Info 
Rattus norvegicus (Rat) -
SKPT-0193 Cl.2
 Cell Line Info 
Rattus norvegicus (Rat) -
RKE
 Cell Line Info 
Rattus norvegicus (Rat) -
LLC-PK1
 Cell Line Info 
Sus scrofa (Pig) -
LLC-GA5-CoL150
 Cell Line Info 
Sus scrofa (Pig) -
PK-15
 Cell Line Info 
Sus scrofa (Pig) -
HKRK-B28
 Cell Line Info 
Sus scrofa (Pig) -
PK15NTD
 Cell Line Info 
Sus scrofa (Pig) -