| Compound ID |
Compound Name |
Compound Formula |
|
CP0063469
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)pyrimidin-5-yl)acetic acid
Show/Hide
|
C25H17F3N2O2
|
2
|
| 1 |
IC50 = 0.012 nM
|
|
|
| 2 |
IC50 = 1.9 nM
|
|
|
|
CP0375801
|
2-(4-(4-chlorophenyl)-2-(diphenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17ClN2O2S
|
2
|
| 1 |
IC50 = 0.072 nM
|
|
|
| 2 |
IC50 = 18 nM
|
|
|
|
CP0453573
|
2-(2-(diphenylamino)-4-(3-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17FN2O2S
|
2
|
| 1 |
IC50 = 0.079 nM
|
|
|
| 2 |
IC50 = 4.4 nM
|
|
|
|
CP0497017
|
2-(2-(1,1-diphenylethyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20FNO2S
|
2
|
| 1 |
IC50 = 0.085 nM
|
|
|
| 2 |
IC50 = 7.9 nM
|
|
|
|
CP0375803
|
2-(2-(diphenylamino)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17FN2O2S
|
2
|
| 1 |
IC50 = 0.098 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0406832
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)thiazol-5-yloxy)acetic acid
Show/Hide
|
C24H16F3NO3S
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 83 nM
|
|
|
|
CP0376527
|
2-(2-(bis(4-fluorophenyl)amino)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H15F3N2O2S
|
2
|
| 1 |
IC50 = 0.24 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0402139
|
2-(2-(bis(4-methoxyphenyl)amino)-4-(3-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H21FN2O4S
|
2
|
| 1 |
IC50 = 0.26 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0499463
|
2-(2-((4-cyanophenyl)(phenyl)amino)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H16FN3O2S
|
2
|
| 1 |
IC50 = 0.46 nM
|
|
|
| 2 |
IC50 = 84 nM
|
|
|
|
CP0372005
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-fluoropyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H15F3N2O2S
|
2
|
| 1 |
IC50 = 0.48 nM
|
|
|
| 2 |
IC50 = 4.7 nM
|
|
|
|
CP0376528
|
3-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)thiazol-5-yl)propanoic acid
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|
C25H18F3NO2S
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 75 nM
|
|
|
|
CP0372016
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H16F3NO2S
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 18 nM
|
|
|
|
CP0384024
|
2-(4-(4-fluorophenyl)-2-(phenyl(pyridin-3-yl)amino)thiazol-5-yl)acetic acid
Show/Hide
|
C22H16FN3O2S
|
2
|
| 1 |
IC50 = 1.5 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
|
CP0406831
|
2-(4-(4-fluorophenyl)-2-((4-(methylsulfonyl)phenyl)(phenyl)amino)thiazol-5-yl)acetic acid
Show/Hide
|
C24H19FN2O4S2
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 190 nM
|
|
|
|
CP0502623
|
2-(2-benzhydryl-4-(3-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18FNO2S
|
2
|
| 1 |
IC50 = 2.9 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
|
CP0383856
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-chloropyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H15ClF2N2O2S
|
2
|
| 1 |
IC50 = 3.1 nM
|
|
|
| 2 |
IC50 = 39 nM
|
|
|
|
CP0492811
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-methylpyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18F2N2O2S
|
2
|
| 1 |
IC50 = 3.1 nM
|
|
|
| 2 |
IC50 = 53 nM
|
|
|
|
CP0417877
|
2-(4-(4-fluorophenyl)-2-((4-hydroxyphenyl)(phenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18FNO3S
|
2
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0417878
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3,4-difluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H15F4NO2S
|
2
|
| 1 |
IC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 41 nM
|
|
|
|
CP0063054
|
2-(4-(4-fluorophenyl)-2-((4-methoxyphenyl)(phenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20FNO3S
|
2
|
| 1 |
IC50 = 3.6 nM
|
|
|
| 2 |
IC50 = 31 nM
|
|
|
|
CP0375782
|
2-(2-(4-chlorobenzyl)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18ClNO3S
|
2
|
| 1 |
IC50 = 3.7 nM
|
|
|
| 2 |
IC50 = 66 nM
|
|
|
|
CP0464006
|
2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C26H22FNO4S
|
2
|
| 1 |
IC50 = 3.9 nM
|
|
|
| 2 |
IC50 = 31 nM
|
|
|
|
CP0498722
|
2-(2-benzhydryl-4-(3,4-difluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H17F2NO2S
|
2
|
| 1 |
IC50 = 4.1 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
|
CP0415297
|
2-(4-(2-aminopyridin-4-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17F2N3O2S
|
2
|
| 1 |
IC50 = 4.8 nM
|
|
|
| 2 |
IC50 = 64 nM
|
|
|
|
CP0491196
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(pyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H16F2N2O2S
|
2
|
| 1 |
IC50 = 5.3 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0502894
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2,6-difluoropyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H14F4N2O2S
|
2
|
| 1 |
IC50 = 5.4 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0464007
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H16F3NO2S
|
2
|
| 1 |
IC50 = 7.5 nM
|
|
|
| 2 |
IC50 = 72 nM
|
|
|
|
CP0372013
|
2-(4-(4-chlorophenyl)-2-((4-methoxyphenyl)(phenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20ClNO3S
|
2
|
| 1 |
IC50 = 8.4 nM
|
|
|
| 2 |
IC50 = 76 nM
|
|
|
|
CP0373541
|
2-(2-benzhydryl-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18FNO2S
|
2
|
| 1 |
IC50 = 8.7 nM
|
|
|
| 2 |
IC50 = 77 nM
|
|
|
|
CP0383847
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H16ClF2NO2S
|
2
|
| 1 |
IC50 = 9.7 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
|
CP0383850
|
2-(2-((3,4-difluorophenyl)(phenyl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H16F3NO2S
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 64 nM
|
|
|
|
CP0034973
|
2-(2-benzhydryl-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18ClNO2S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
|
CP0372015
|
2-(2-((4-chlorophenyl)(phenyl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H17ClFNO2S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 79 nM
|
|
|
|
CP0491195
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(furan-3-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C22H15F2NO3S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
|
CP0464004
|
2-(2-(bis(4-fluorophenyl)methyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C24H17F2NO2S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 240 nM
|
|
|
|
CP0506301
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(1H-pyrazol-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C21H15F2N3O2S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 220 nM
|
|
|
|
CP0464003
|
2-(4-(4-chlorophenyl)-2-((4-fluorophenyl)(phenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H17ClFNO2S
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0371818
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(furan-2-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C22H15F2NO3S
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
|
CP0372002
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-cyanophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H16F2N2O2S
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 220 nM
|
|
|
|
CP0498738
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-(methylamino)pyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H19F2N3O2S
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 170 nM
|
|
|
|
CP0372006
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-methoxypyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18F2N2O3S
|
2
|
| 1 |
IC50 = 29 nM
|
|
|
| 2 |
IC50 = 380 nM
|
|
|
|
CP0372055
|
2-(2-((4-chlorophenoxy)methyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C18H13Cl2NO3S
|
2
|
| 1 |
IC50 = 32 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
|
CP0372000
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3,5-difluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H15F4NO2S
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
|
CP0373383
|
2-(4-(biphenyl-4-yl)-2-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C23H17NO2S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0373533
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-(methylsulfonamido)phenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20F2N2O4S2
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
|
CP0371813
|
2-(4-(4-chlorophenyl)-2-(naphthalen-1-ylmethyl)thiazol-5-yl)acetic acid
Show/Hide
|
C22H16ClNO2S
|
2
|
| 1 |
IC50 = 41 nM
|
|
|
| 2 |
IC50 = 570 nM
|
|
|
|
CP0401657
|
2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18ClNO2S
|
2
|
| 1 |
IC50 = 41 nM
|
|
|
| 2 |
IC50 = 510 nM
|
|
|
|
CP0491193
|
2-(4-(4-chlorophenyl)-2-((4-chlorophenyl)(phenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H17Cl2NO2S
|
2
|
| 1 |
IC50 = 45 nM
|
|
|
| 2 |
IC50 = 75 nM
|
|
|
|
CP0491197
|
2-(2-(1-acetyl-4-phenylpiperidin-4-yl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H23ClN2O3S
|
2
|
| 1 |
IC50 = 52 nM
|
|
|
| 2 |
IC50 = 550 nM
|
|
|
|
CP0401967
|
2-(4-(4-chlorophenyl)-2-(1,2-diphenylethyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20ClNO2S
|
2
|
| 1 |
IC50 = 56 nM
|
|
|
| 2 |
IC50 = 510 nM
|
|
|
|
CP0373542
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-cyano-4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H15F3N2O2S
|
2
|
| 1 |
IC50 = 57 nM
|
|
|
| 2 |
IC50 = 520 nM
|
|
|
|
CP0371815
|
2-(4-(4-chlorophenyl)-2-((4-methoxyphenyl)(pyridin-2-yl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H19ClN2O3S
|
2
|
| 1 |
IC50 = 61 nM
|
|
|
| 2 |
IC50 = 310 nM
|
|
|
|
CP0372004
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(pyridin-3-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H16F2N2O2S
|
2
|
| 1 |
IC50 = 68 nM
|
|
|
| 2 |
IC50 = 510 nM
|
|
|
|
CP0492812
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-hydroxypyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H16F2N2O3S
|
2
|
| 1 |
IC50 = 68 nM
|
|
|
| 2 |
IC50 = 890 nM
|
|
|
|
CP0372009
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(5-fluoropyridin-3-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H15F3N2O2S
|
2
|
| 1 |
IC50 = 71 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
|
CP0373540
|
2-(4-(4-chlorophenyl)-2-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H16ClNO3S
|
2
|
| 1 |
IC50 = 93 nM
|
|
|
| 2 |
IC50 = 1300 nM
|
|
|
|
CP0372012
|
2-(4-(4-chlorophenyl)-2-(naphthalen-1-ylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C21H15ClN2O2S
|
2
|
| 1 |
IC50 = 96 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0050007
|
2-(4-(4-chlorophenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C17H13ClN2O2S
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 1300 nM
|
|
|
|
CP0464009
|
2-(4-(6-aminopyridin-3-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17F2N3O2S
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 500 nM
|
|
|
|
CP0372003
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-sulfamoylphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18F2N2O4S2
|
2
|
| 1 |
IC50 = 140 nM
|
|
|
| 2 |
IC50 = 710 nM
|
|
|
|
CP0372001
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(4-cyanophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H16F2N2O2S
|
2
|
| 1 |
IC50 = 150 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0415087
|
2-(2-(4-phenoxyphenyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C23H17NO3S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0430741
|
2-(2-benzyl-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C18H14FNO2S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0371871
|
2-(4-(4-chlorophenyl)-2-(1-phenylpropyl)thiazol-5-yl)acetic acid
Show/Hide
|
C20H18ClNO2S
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0500156
|
2-(2-((4'-cyanobiphenyl-2-yl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H17FN2O2S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0372017
|
2-(4-(2-amino-6-fluoropyridin-4-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H16F3N3O2S
|
2
|
| 1 |
IC50 = 220 nM
|
|
|
| 2 |
IC50 = 1400 nM
|
|
|
|
CP0383300
|
2-(2-(4-chlorobenzyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C18H13Cl2NO2S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0417886
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(2-(pyrrolidin-1-yl)pyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C27H23F2N3O2S
|
2
|
| 1 |
IC50 = 230 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0372054
|
2-(4-(4-chlorophenyl)-2-(phenylthiomethyl)thiazol-5-yl)acetic acid
Show/Hide
|
C18H14ClNO2S2
|
2
|
| 1 |
IC50 = 250 nM
|
|
|
| 2 |
IC50 = 450 nM
|
|
|
|
CP0499105
|
2-(2-(naphthalen-2-ylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C27H20N2O3S
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0383298
|
2-(4-(4-fluorophenyl)-2-((4'-methoxybiphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
Show/Hide
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C25H20FNO3S
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1
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| 1 |
IC50 = 270 nM
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CP0492809
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2-(2-(bis(4-fluorophenyl)methyl)-4-(1H-pyrazol-5-yl)thiazol-5-yl)acetic acid
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C21H15F2N3O2S
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2
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| 1 |
IC50 = 280 nM
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| 2 |
IC50 = 3300 nM
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CP0491192
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2-(4-(4-chlorophenyl)-2-(2,2-diphenylethyl)thiazol-5-yl)acetic acid
Show/Hide
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C25H20ClNO2S
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2
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| 1 |
IC50 = 340 nM
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| 2 |
IC50 = 32000 nM
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CP0373387
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2-(4-(4-phenoxyphenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
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C23H18N2O3S
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1
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| 1 |
IC50 = 350 nM
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CP0514879
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2-(4-(2-(4-acetylpiperazin-1-yl)pyridin-4-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
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C29H26F2N4O3S
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2
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| 1 |
IC50 = 360 nM
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| 2 |
IC50 > 100000 nM
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CP0371998
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2-(2-benzhydryl-4-(4-methoxyphenyl)thiazol-5-yl)acetic acid
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C25H21NO3S
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2
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| 1 |
IC50 = 370 nM
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| 2 |
IC50 = 910 nM
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CP0447815
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2-(2-benzhydryl-4-phenylthiazol-5-yl)acetic acid
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C24H19NO2S
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2
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| 1 |
IC50 = 370 nM
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| 2 |
IC50 = 570 nM
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CP0499141
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2-(2-(biphenyl-2-ylmethyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
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C24H18FNO2S
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1
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| 1 |
IC50 = 370 nM
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CP0502383
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2-(4-(4-bromophenyl)-2-(naphthalen-2-ylamino)thiazol-5-yl)acetic acid
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C21H15BrN2O2S
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1
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| 1 |
IC50 = 370 nM
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CP0492810
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2-(2-(bis(4-fluorophenyl)methyl)-4-(2-(dimethylamino)pyridin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
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C25H21F2N3O2S
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2
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| 1 |
IC50 = 380 nM
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| 2 |
IC50 > 100000 nM
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CP0447813
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2-(4-(4-chlorophenyl)-2-(phenethylamino)thiazol-5-yl)acetic acid
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C19H17ClN2O2S
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2
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| 1 |
IC50 = 390 nM
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| 2 |
IC50 = 650 nM
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CP0401656
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2-(4-(4-fluorophenyl)-2-((3'-methoxybiphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
Show/Hide
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C25H20FNO3S
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1
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| 1 |
IC50 = 390 nM
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CP0415287
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2-(2-(benzylamino)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
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C18H15ClN2O2S
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2
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| 1 |
IC50 = 440 nM
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| 2 |
IC50 = 2300 nM
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CP0430749
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2-(4-(4-methoxyphenyl)-2-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
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C24H19NO4S
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1
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| 1 |
IC50 = 470 nM
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CP0497048
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2-(2-(2-methoxyphenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
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C24H20N2O4S
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1
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| 1 |
IC50 = 480 nM
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CP0464001
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2-(4-(4-chlorophenyl)-2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazol-5-yl)acetic acid
Show/Hide
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C19H14ClNO4S
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2
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| 1 |
IC50 = 500 nM
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| 2 |
IC50 = 2000 nM
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CP0502344
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2-(2-benzamido-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
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C18H13ClN2O3S
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2
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| 1 |
IC50 = 520 nM
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| 2 |
IC50 = 870 nM
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CP0372056
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2-(4-(4-chlorophenyl)-2-(cyclohexyl(phenyl)methyl)thiazol-5-yl)acetic acid
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C24H24ClNO2S
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2
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| 1 |
IC50 = 530 nM
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| 2 |
IC50 > 100000 nM
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CP0430743
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2-(2-(4-fluorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
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C23H17FN2O3S
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1
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| 1 |
IC50 = 540 nM
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CP0388167
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2-(4-(4-chlorophenyl)-2-phenylthiazol-5-yl)acetic acid
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C17H12ClNO2S
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2
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| 1 |
IC50 = 550 nM
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| 2 |
IC50 = 960 nM
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CP0401659
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2-(4-(4-chlorophenyl)-2-(p-tolylamino)thiazol-5-yl)acetic acid
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C18H15ClN2O2S
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1
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| 1 |
IC50 = 560 nM
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CP0415100
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2-(4-(4-chlorophenyl)-2-(naphthalen-2-ylmethyl)thiazol-5-yl)acetic acid
Show/Hide
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C22H16ClNO2S
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1
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| 1 |
IC50 = 570 nM
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CP0421572
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2-(2-(4-chlorobenzyl)-4-phenylthiazol-5-yl)acetic acid
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C18H14ClNO2S
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1
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| 1 |
IC50 = 580 nM
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CP0492808
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2-(2-(bis(4-fluorophenyl)methyl)-4-(3-(methylsulfonyl)phenyl)thiazol-5-yl)acetic acid
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C25H19F2NO4S2
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2
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| 1 |
IC50 = 590 nM
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| 2 |
IC50 = 6300 nM
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CP0502628
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2-(4-(2-(azetidin-1-yl)pyridin-4-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
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C26H21F2N3O2S
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2
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| 1 |
IC50 = 660 nM
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| 2 |
IC50 > 100000 nM
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CP0415288
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2-(4-(4-chlorophenyl)-2-((4-chlorophenylsulfonyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
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C18H13Cl2NO4S2
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2
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| 1 |
IC50 = 730 nM
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| 2 |
IC50 = 1500 nM
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CP0401661
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2-(4-(4-chlorophenyl)-2-(2-methoxyphenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C18H15ClN2O3S
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1
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| 1 |
IC50 = 730 nM
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CP0491198
|
2-(4-(4-chlorophenyl)-2-(phenyl(pyridin-2-yl)methyl)thiazol-5-yl)acetic acid
Show/Hide
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C23H17ClN2O2S
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2
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| 1 |
IC50 = 810 nM
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| 2 |
IC50 = 1900 nM
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CP0430798
|
2-(2-(4-methoxyphenyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C18H15NO3S
|
1
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| 1 |
IC50 = 820 nM
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CP0430794
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2-(2-(4-chlorobenzyl)-4-(4-methoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C19H16ClNO3S
|
1
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| 1 |
IC50 = 850 nM
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CP0453093
|
2-(4-(4-fluorophenyl)-2-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C17H12FNO2S
|
1
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| 1 |
IC50 = 860 nM
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CP0493304
|
2-(2,4-diphenylthiazol-5-yl)acetic acid
Show/Hide
|
C17H13NO2S
|
1
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| 1 |
IC50 = 870 nM
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CP0371870
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2-(4-(6-amino-5-methylpyridin-3-yl)-2-(bis(4-fluorophenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H19F2N3O2S
|
2
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| 1 |
IC50 = 880 nM
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| 2 |
IC50 > 100000 nM
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CP0180268
|
2-(2-(4-chlorophenyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C17H12ClNO2S
|
1
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| 1 |
IC50 = 990 nM
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CP0371999
|
2-(2-benzhydryl-4-(4-(trifluoromethyl)phenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H18F3NO2S
|
2
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| 1 |
IC50 = 1100 nM
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| 2 |
IC50 > 100000 nM
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CP0430745
|
2-(4-(4-chlorophenyl)-2-(4-(trifluoromethyl)phenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C18H12ClF3N2O2S
|
1
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| 1 |
IC50 = 1100 nM
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CP0517559
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2-(4-(biphenyl-4-yl)-2-(phenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C23H18N2O2S
|
1
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| 1 |
IC50 = 1200 nM
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CP0463375
|
2-(2-(bis(4-fluorophenyl)amino)-4-(3-fluorophenyl)pyrimidin-5-yl)acetic acid
Show/Hide
|
C24H16F3N3O2
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2
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| 1 |
IC50 = 1260 nM
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| 2 |
IC50 > 100 nM
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CP0373543
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2-(2-(bis(4-fluorophenyl)methyl)-4-(1-methyl-1H-pyrazol-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C22H17F2N3O2S
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2
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| 1 |
IC50 = 1300 nM
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| 2 |
IC50 = 3500 nM
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CP0485993
|
2-(4-(4-fluorophenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C17H13FN2O2S
|
1
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| 1 |
IC50 = 1300 nM
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CP0485994
|
2-(4-(4-ethylphenyl)-2-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C19H17NO2S
|
1
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| 1 |
IC50 = 1300 nM
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CP0492807
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2-(2-(bis(4-fluorophenyl)methyl)-4-(4-sulfamoylphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18F2N2O4S2
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2
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| 1 |
IC50 = 1500 nM
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| 2 |
IC50 > 100000 nM
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CP0045666
|
2-(4-phenyl-2-(phenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C17H14N2O2S
|
1
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| 1 |
IC50 = 1500 nM
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CP0383303
|
2-(2-(4-fluorophenyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C17H12FNO2S
|
1
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| 1 |
IC50 = 1500 nM
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CP0488943
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2-(2-(4-methoxyphenylamino)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C18H16N2O3S
|
1
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| 1 |
IC50 = 1500 nM
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CP0510466
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2-(2-(2-(benzo[d][1,3]dioxol-5-yl)benzyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H18FNO4S
|
1
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| 1 |
IC50 = 1500 nM
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CP0421571
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2-(2-(4-methylbenzyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C19H17NO2S
|
1
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| 1 |
IC50 = 1800 nM
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CP0453089
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2-(4-(biphenyl-4-yl)-2-(2-methoxyphenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C24H20N2O3S
|
1
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| 1 |
IC50 = 1900 nM
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CP0488954
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2-(2-(4-chlorophenylamino)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C17H12ClFN2O2S
|
1
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| 1 |
IC50 = 1900 nM
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CP0497597
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3-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)pyrimidin-5-yl)propanoic acid
Show/Hide
|
C26H19F3N2O2
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2
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| 1 |
IC50 = 2070 nM
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| 2 |
IC50 > 100 nM
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CP0430747
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2-(4-(4-fluorophenyl)-2-(2-methoxyphenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C18H15FN2O3S
|
1
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| 1 |
IC50 = 2100 nM
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CP0373368
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2-(4-(4-methoxyphenyl)-2-(phenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C18H16N2O3S
|
1
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| 1 |
IC50 = 2400 nM
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CP0497598
|
2-(2-(bis(4-methoxyphenyl)amino)-4-(3-fluorophenyl)pyrimidin-5-yl)acetic acid
Show/Hide
|
C26H22FN3O4
|
2
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| 1 |
IC50 = 2790 nM
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| 2 |
IC50 > 100 nM
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CP0502343
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2-(4-(4-chlorophenyl)-2-(4-phenylpiperidin-4-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C22H21ClN2O2S
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2
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| 1 |
IC50 = 2900 nM
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| 2 |
IC50 > 100000 nM
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CP0372014
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2-(4-(4-chlorophenyl)-2-((6-chloropyridin-2-yl)(phenyl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H16Cl2N2O2S
|
2
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| 1 |
IC50 = 3200 nM
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| 2 |
IC50 > 100000 nM
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CP0477653
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2-(4-(4-chlorophenyl)-2-(furan-2-yl)thiazol-5-yl)acetic acid
Show/Hide
|
C15H10ClNO3S
|
1
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| 1 |
IC50 = 3800 nM
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CP0383004
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2-(2-(3,4-dimethoxybenzyl)-4-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C20H19NO4S
|
1
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| 1 |
IC50 = 3800 nM
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CP0383013
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2-(4-(biphenyl-4-yl)-2-(4-chlorophenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17ClN2O2S
|
1
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| 1 |
IC50 = 3800 nM
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CP0373382
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2-(2-benzyl-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C18H14ClNO2S
|
1
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| 1 |
IC50 = 4100 nM
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CP0489547
|
2-(4-(4-methoxyphenyl)-2-phenylthiazol-5-yl)acetic acid
Show/Hide
|
C18H15NO3S
|
1
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| 1 |
IC50 = 7000 nM
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CP0461005
|
2-(2-(bis(4-fluorophenyl)methyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)acetic acid
Show/Hide
|
C24H17F3N2O2
|
2
|
| 1 |
IC50 = 9140 nM
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| 2 |
IC50 > 100 nM
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CP0371816
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2-(2-benzhydryl-4-(5-chloro-2-methoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20ClNO3S
|
2
|
| 1 |
IC50 = 9400 nM
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| 2 |
IC50 > 100000 nM
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CP0471569
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2-(4-(4-chlorophenyl)-2-(4-isopropylphenylamino)thiazol-5-yl)acetic acid
Show/Hide
|
C20H19ClN2O2S
|
1
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| 1 |
IC50 = 16000 nM
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CP0452734
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2-(4-(4-chlorophenyl)-2-methylthiazol-5-yl)acetic acid
Show/Hide
|
C12H10ClNO2S
|
1
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| 1 |
IC50 = 41000 nM
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CP0373525
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2-(2-amino-4-(4-chlorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C11H9ClN2O2S
|
1
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| 1 |
IC50 > 100000 nM
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CP0477652
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2-(2-benzhydryl-4-(2,5-dimethoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C26H23NO4S
|
2
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| 1 |
IC50 > 100000 nM
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| 2 |
IC50 > 105 nM
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CP0373386
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2-(2-(2-fluorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17FN2O3S
|
1
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| 1 |
IC50 > 100000 nM
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CP0373555
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2-(4-(4-fluorophenyl)-2-((3'-(trifluoromethoxy)biphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H17F4NO3S
|
1
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| 1 |
IC50 > 100000 nM
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CP0383273
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2-(2-((3'-cyanobiphenyl-2-yl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H17FN2O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
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CP0383274
|
2-(2-(2-chlorophenylamino)-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C23H17ClN2O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
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CP0383356
|
2-(4-(4-fluorophenyl)-2-((2'-methoxybiphenyl-2-yl)methyl)thiazol-5-yl)acetic acid
Show/Hide
|
C25H20FNO3S
|
1
|
| 1 |
IC50 > 100000 nM
|
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CP0417837
|
2-(2-(2-bromobenzyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid
Show/Hide
|
C18H13BrFNO2S
|
1
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| 1 |
IC50 > 100000 nM
|
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CP0510459
|
2-(4-(4-chlorophenyl)-2-(2-phenoxybenzyl)thiazol-5-yl)acetic acid
Show/Hide
|
C24H18ClNO3S
|
1
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| 1 |
IC50 > 100000 nM
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