Protein Information

General Information of the Protein

Protein ID	PT01171
Protein Name	Prostaglandin D2 receptor 2
Secondarily Protein Name	Chemoattractant receptor-homologous molecule expressed on Th2 cells G-protein coupled receptor 44
Gene Name	PTGDR2
Secondarily Gene Name	CRTH2 DL1R GPR44
Sequence	MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRPEEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Small molecule receptor (family A GPCR) > Lipid-like ligand receptor (family A GPCR) > Prostanoid receptor
Function	Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses. Show/Hide
Uniprot ID	Primary ID: Q9Y5Y4 Secondarily ID: O94765 Q4QRI6 Show/Hide
Ensembl ID	ENSG00000183134
HGNC ID	HGNC:4502
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000011 , CHO

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0478164 Compound Info	4-{5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}butanoic acid Show/Hide	C22H18ClFN2O5	2
1	EC50 = 2200 nM Bioactivity Info	TI LI LO TS
2	Ki = 1759 nM Bioactivity Info	TI LI LO TS
CP0505209 Compound Info	4-{5-chloro-1'-[(4-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}butanoic acid Show/Hide	C22H18Cl2N2O5	2
1	EC50 = 5600 nM Bioactivity Info	TI LI LO TS
2	Ki = 758 nM Bioactivity Info	TI LI LO TS
CP0385506 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C21H22FN5O3	2
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0389705 Compound Info	2-[1-[4-(1H-indole-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H19N3O4	2
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3.5 nM Bioactivity Info	TI LI LO TS
CP0524697 Compound Info	2-[1-[4-[(3-chlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17ClN2O4	1
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
CP0387883 Compound Info	2-[1-[4-[(4-chlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17ClN2O4	1
1	IC50 = 3.4 nM Bioactivity Info	TI LI LO TS
CP0113938 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]-2-phenylacetamide Show/Hide	C23H20FN5O3S	2
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0551799 Compound Info	2-[1-[4-[2-(3,4-dichlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H20Cl2N2O4	1
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
CP0420654 Compound Info	2-[1-[4-(1-benzofuran-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H18N2O5	1
1	IC50 = 3.8 nM Bioactivity Info	TI LI LO TS
CP0386064 Compound Info	2-[1-[4-(naphthalene-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C29H20N2O4	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0476029 Compound Info	2-[1-[4-[[(E)-3-(3,4-dichlorophenyl)prop-2-enoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H18Cl2N2O4	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0519814 Compound Info	2-[1-[4-[[4-(trifluoromethyl)benzoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H17F3N2O4	1
1	IC50 = 4.9 nM Bioactivity Info	TI LI LO TS
CP0420653 Compound Info	2-[1-[4-[(4-methylbenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H20N2O4	1
1	IC50 = 5.2 nM Bioactivity Info	TI LI LO TS
CP0387881 Compound Info	2-[1-[4-[(3,4-dichlorophenyl)methylamino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H18Cl2N2O3	1
1	IC50 = 6.1 nM Bioactivity Info	TI LI LO TS
CP0386062 Compound Info	2-[1-[4-[[4-(dimethylamino)benzoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H23N3O4	1
1	IC50 = 6.2 nM Bioactivity Info	TI LI LO TS
CP0387882 Compound Info	2-[1-[4-[(3,4-dichlorophenyl)methoxycarbonylamino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H18Cl2N2O5	1
1	IC50 = 6.7 nM Bioactivity Info	TI LI LO TS
CP0154904 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C20H19ClO5S	3
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 32 nM Bioactivity Info	TI LI LO TS
3	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0549646 Compound Info	2-[1-[4-[(4-methoxybenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H20N2O5	1
1	IC50 = 7.3 nM Bioactivity Info	TI LI LO TS
CP0380031 Compound Info	2-[1-[4-[2-(4-chlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H21ClN2O4	1
1	IC50 = 7.8 nM Bioactivity Info	TI LI LO TS
CP0420652 Compound Info	2-[1-[4-[(4-cyanobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H17N3O4	1
1	IC50 = 7.8 nM Bioactivity Info	TI LI LO TS
CP0387884 Compound Info	2-[1-(4-benzamidobenzoyl)isoquinolin-4-yl]acetic acid Show/Hide	C25H18N2O4	1
1	IC50 = 7.9 nM Bioactivity Info	TI LI LO TS
CP0395103 Compound Info	2-[4-chloro-2-[2-(2-fluoro-5-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H16ClFO5S	3
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 28 nM Bioactivity Info	TI LI LO TS
3	Ki = 3.4 nM Bioactivity Info	TI LI LO TS
CP0551800 Compound Info	2-[1-[4-[(4-chlorophenyl)carbamoyl]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17ClN2O4	1
1	IC50 = 8.2 nM Bioactivity Info	TI LI LO TS
CP0424092 Compound Info	(S)-2-(4-chloro-2-((4-(2-(4-fluorophenyl)acetyl)-3-methylpiperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C22H24ClFN2O4	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0498085 Compound Info	2-[4-chloro-2-[[(3S)-4-[2-(4-chlorophenyl)acetyl]-3-methylpiperazin-1-yl]methyl]phenoxy]acetic acid Show/Hide	C22H24Cl2N2O4	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0484520 Compound Info	2-[1-[4-[(4-nitrobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17N3O6	1
1	IC50 = 9.9 nM Bioactivity Info	TI LI LO TS
CP0290305 Compound Info	2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid Show/Hide	C15H10ClNO3	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0409058 Compound Info	2-[1-[4-[(3,4-dichlorophenyl)carbamoyl]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H16Cl2N2O4	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0415476 Compound Info	N-[3-chloro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methoxyphenyl)methyl]pentanamide Show/Hide	C20H22ClN5O2	2
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0447086 Compound Info	(S)-2-(2-((4-(benzylsulfonyl)-3-methylpiperazin-1-yl)methyl)-4-chlorophenyl)acetic acid Show/Hide	C21H25ClN2O4S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0386063 Compound Info	2-[1-[4-[[4-(trifluoromethoxy)benzoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H17F3N2O5	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0555896 Compound Info	2-[1-[4-[3-(4-chlorophenyl)propoxy]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H22ClNO4	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0531041 Compound Info	2-[1-[4-[2-(4-chlorophenyl)ethoxy]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H20ClNO4	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0498086 Compound Info	(S)-2-(4-chloro-2-((4-(phenylsulfonyl)-3-propylpiperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C22H27ClN2O5S	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0387887 Compound Info	2-[1-[4-[3-(3,4-dichlorophenyl)propanoylamino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C27H20Cl2N2O4	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0549647 Compound Info	2-[1-[4-[(3,4-dichlorophenyl)carbamoylamino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17Cl2N3O4	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0409056 Compound Info	2-[1-[4-(cyclohexanecarbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H24N2O4	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0392650 Compound Info	2-[1-[4-[(4-phenoxybenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C31H22N2O5	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0432735 Compound Info	2-[1-[4-[[2-(3,4-dichlorophenyl)acetyl]amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H18Cl2N2O4	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0399932 Compound Info	(S)-2-(4-chloro-2-((3-methyl-4-(phenylsulfonyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C20H23ClN2O5S	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0399934 Compound Info	(S)-2-(4-chloro-2-((4-(2-(2-chlorophenyl)acetyl)-3-methylpiperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C22H24Cl2N2O4	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0506025 Compound Info	2-(2-((4-(benzylsulfonyl)piperazin-1-yl)methyl)-4-chlorophenoxy)acetic acid Show/Hide	C20H23ClN2O5S	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0522682 Compound Info	2-[4-chloro-2-[[(3S)-4-[2-(4-chlorophenyl)acetyl]-3-methylpiperazin-1-yl]methyl]phenyl]acetic acid Show/Hide	C22H24Cl2N2O3	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0392651 Compound Info	2-[1-[4-[(4-phenylbenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C31H22N2O4	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0424657 Compound Info	2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,5'-dione}acetic acid Show/Hide	C24H20ClN3O5	2
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.8 nM Bioactivity Info	TI LI LO TS
CP0056577 Compound Info	2-[1-[4-[(3,4-dichlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H16Cl2N2O4	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0139382 Compound Info	N-[3-chloro-5-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethoxy)phenyl]methyl]pentanamide Show/Hide	C20H19ClF3N5O2	2
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
2	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0386065 Compound Info	2-[1-[4-[(2-cyclohexylacetyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H26N2O4	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0435032 Compound Info	2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C24H18ClN3O6	2
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
2	Ki = 7.6 nM Bioactivity Info	TI LI LO TS
CP0489856 Compound Info	2-[1-[4-[[2-(1-adamantyl)acetyl]amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C30H30N2O4	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0485747 Compound Info	2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C24H18ClN3O6	2
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0399653 Compound Info	2-[1-[4-[2-(4-chlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]oxyacetic acid Show/Hide	C27H21ClN2O5	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0378230 Compound Info	2-[1-(4-chlorophenyl)sulfonyl-5-fluoro-2-methylindol-3-yl]acetic acid Show/Hide	C17H13ClFNO4S	2
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
2	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0500985 Compound Info	(S)-2-(4-chloro-2-((3-methyl-4-(2-phenylacetyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C22H25ClN2O4	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0447088 Compound Info	(S)-2-(4-chloro-2-((4-(2-(3-chlorophenyl)acetyl)-3-methylpiperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C22H24Cl2N2O4	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0164558 Compound Info	2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl)biphenyl-2-yloxy)acetic acid Show/Hide	C18H17F3O5S	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0297983 Compound Info	2-[4-chloro-2-[2-(3-chlorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H10Cl2O3	5
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
2	IC50 = 104 nM Bioactivity Info	TI LI LO TS
3	IC50 = 114 nM Bioactivity Info	TI LI LO TS
4	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
5	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0502399 Compound Info	2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C19H17N3O5S	2
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
2	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0447087 Compound Info	(S)-2-(4-chloro-2-((3-ethyl-4-(phenylsulfonyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C21H25ClN2O5S	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0906028 Compound Info	rac-2-(4-chloro-2-((3-methyl-4-(phenylsulfonyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C20H23ClN2O5S	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0484522 Compound Info	2-[1-[4-(naphthalene-1-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C29H20N2O4	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0066158 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide Show/Hide	C18H15F4N5O	2
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.7 nM Bioactivity Info	TI LI LO TS
CP0054111 Compound Info	2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H18N2O4S	3
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
2	Kd = 15.14 nM Bioactivity Info	TI LI LO TS
3	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0380963 Compound Info	2-[1-[4-[(3,4-dichlorophenyl)methoxy]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17Cl2NO4	1
1	IC50 = 38 nM Bioactivity Info	TI LI LO TS
CP0425641 Compound Info	(S)-2-(4-chloro-2-((4-(2-(4-chlorophenyl)-2-methylpropanoyl)-3-methylpiperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C24H28Cl2N2O4	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0404910 Compound Info	2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H12ClN3O4S	2
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
2	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0391849 Compound Info	2-[1-(2,5-dichlorophenyl)sulfonyl-5-fluoro-2-methylindol-3-yl]acetic acid Show/Hide	C17H12Cl2FNO4S	2
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
2	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0409057 Compound Info	2-[1-[4-[(2-chlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C25H17ClN2O4	1
1	IC50 = 45 nM Bioactivity Info	TI LI LO TS
CP0133932 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-3-methyl-N-[(4-methylsulfonylphenyl)methyl]butanamide Show/Hide	C20H22FN5O3S	2
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0435033 Compound Info	2-{5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13Cl2FN2O5	2
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
2	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0505203 Compound Info	2-(5-chloro-1'-{[2-(3-chlorophenyl)-1,3-thiazol-4-yl]methyl}-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione)acetic acid Show/Hide	C23H15Cl2N3O5S	2
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
2	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0566214 Compound Info	2-[1-[4-(pyridine-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C24H17N3O4	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0387885 Compound Info	2-[1-[4-(cyclopropanecarbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C22H18N2O4	1
1	IC50 = 50 nM Bioactivity Info	TI LI LO TS
CP0153959 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]cyclopentanecarboxamide Show/Hide	C21H22FN5O3S	2
1	IC50 = 57 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.4 nM Bioactivity Info	TI LI LO TS
CP0245256 Compound Info	2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H12F2N2O4S	2
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
2	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0420584 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(3-methoxyphenyl)methyl]propanamide Show/Hide	C18H18FN5O2	2
1	IC50 = 64 nM Bioactivity Info	TI LI LO TS
2	Ki = 8.2 nM Bioactivity Info	TI LI LO TS
CP0160937 Compound Info	2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H13Cl2FN2O5	2
1	IC50 = 66 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.3 nM Bioactivity Info	TI LI LO TS
CP0489810 Compound Info	2-[1-[4-(1,3-thiazole-4-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C22H15N3O4S	1
1	IC50 = 67 nM Bioactivity Info	TI LI LO TS
CP0447089 Compound Info	2-[2-[[4-(benzenesulfonyl)-2-methylpiperazin-1-yl]methyl]-4-chlorophenoxy]acetic acid Show/Hide	C20H23ClN2O5S	1
1	IC50 = 71 nM Bioactivity Info	TI LI LO TS
CP0432066 Compound Info	2-{5-chloro-1'-[(3,5-dichlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13Cl3N2O5	2
1	IC50 = 82 nM Bioactivity Info	TI LI LO TS
2	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0530736 Compound Info	2-[1-[4-(pyridine-4-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C24H17N3O4	1
1	IC50 = 83 nM Bioactivity Info	TI LI LO TS
CP0169760 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(3-hydroxyphenyl)methyl]propanamide Show/Hide	C17H16FN5O2	2
1	IC50 = 85 nM Bioactivity Info	TI LI LO TS
2	Ki = 26 nM Bioactivity Info	TI LI LO TS
CP0503269 Compound Info	2-(2-((4-(benzylsulfonyl)-1,4-diazepan-1-yl)methyl)-4-chlorophenoxy)acetic acid Show/Hide	C21H25ClN2O5S	1
1	IC50 = 89 nM Bioactivity Info	TI LI LO TS
CP0503954 Compound Info	2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H15FN2O5S	2
1	IC50 = 91 nM Bioactivity Info	TI LI LO TS
2	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0377112 Compound Info	2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H12FN3O4S	2
1	IC50 = 101 nM Bioactivity Info	TI LI LO TS
2	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0109477 Compound Info	2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H14Cl2N2O5	2
1	IC50 = 107 nM Bioactivity Info	TI LI LO TS
2	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0529890 Compound Info	2-{5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H14Cl2N2O5	2
1	IC50 = 122 nM Bioactivity Info	TI LI LO TS
2	Ki = 68 nM Bioactivity Info	TI LI LO TS
CP0379870 Compound Info	2-[2-methyl-1-[(4-nitrophenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H15N3O4	2
1	IC50 = 143 nM Bioactivity Info	TI LI LO TS
2	Ki = 147 nM Bioactivity Info	TI LI LO TS
CP0438204 Compound Info	2-[2-methyl-1-[[4-(trifluoromethylsulfonyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H15F3N2O4S	2
1	IC50 = 147 nM Bioactivity Info	TI LI LO TS
2	Ki = 208 nM Bioactivity Info	TI LI LO TS
CP0201722 Compound Info	2-(4-chloro-2-cycloheptylphenoxy)acetic acid Show/Hide	C15H19ClO3	2
1	IC50 = 148 nM Bioactivity Info	TI LI LO TS
2	Ki = 59 nM Bioactivity Info	TI LI LO TS
CP0259564 Compound Info	2-[5-fluoro-2-methyl-1-(4-methylsulfonylphenyl)sulfonylindol-3-yl]acetic acid Show/Hide	C18H16FNO6S2	2
1	IC50 = 158 nM Bioactivity Info	TI LI LO TS
2	Ki = 68 nM Bioactivity Info	TI LI LO TS
CP0503860 Compound Info	2-[5-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylindol-3-yl]acetic acid Show/Hide	C17H13F2NO4S	2
1	IC50 = 158 nM Bioactivity Info	TI LI LO TS
2	Ki = 71 nM Bioactivity Info	TI LI LO TS
CP0435034 Compound Info	2-{5-chloro-1'-[(4-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H14ClFN2O5	2
1	IC50 = 182 nM Bioactivity Info	TI LI LO TS
2	Ki = 96 nM Bioactivity Info	TI LI LO TS
CP0405110 Compound Info	2-[2-[(4-benzoyl-3-methylpiperazin-1-yl)methyl]-4-chlorophenoxy]acetic acid Show/Hide	C21H23ClN2O4	1
1	IC50 = 199 nM Bioactivity Info	TI LI LO TS
CP0380962 Compound Info	2-[1-[4-[2-(4-chlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]-2-methylpropanoic acid Show/Hide	C29H25ClN2O4	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0511333 Compound Info	2-[2-[[4-(benzenesulfonyl)piperazin-1-yl]methyl]-4-chlorophenoxy]acetic acid Show/Hide	C19H21ClN2O5S	1
1	IC50 = 201 nM Bioactivity Info	TI LI LO TS
CP0048953 Compound Info	(R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid Show/Hide	C21H21FN2O4S	3
1	IC50 = 210 nM Bioactivity Info	TI LI LO TS
2	IC50 = 461 nM Bioactivity Info	TI LI LO TS
3	Ki = 73 nM Bioactivity Info	TI LI LO TS
CP0476028 Compound Info	2-[1-[4-[(3,4-dichlorobenzoyl)-methylamino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C26H18Cl2N2O4	1
1	IC50 = 210 nM Bioactivity Info	TI LI LO TS
CP0405206 Compound Info	2-{5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H14ClFN2O5	2
1	IC50 = 212 nM Bioactivity Info	TI LI LO TS
2	Ki = 37 nM Bioactivity Info	TI LI LO TS
CP0485749 Compound Info	2-{5-chloro-1'-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C19H16ClN3O6	2
1	IC50 = 220 nM Bioactivity Info	TI LI LO TS
2	Ki = 51 nM Bioactivity Info	TI LI LO TS
CP0054115 Compound Info	2-[2-methyl-1-[(4-methylsulfinylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H18N2O3S	2
1	IC50 = 233 nM Bioactivity Info	TI LI LO TS
2	Ki = 249 nM Bioactivity Info	TI LI LO TS
CP0427740 Compound Info	2-{5-chloro-1'-[(2-methyl-1,3-thiazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C18H14ClN3O5S	2
1	IC50 = 236 nM Bioactivity Info	TI LI LO TS
2	Ki = 38 nM Bioactivity Info	TI LI LO TS
CP0473220 Compound Info	(R)-2-(4-chloro-2-((3-methyl-4-(phenylsulfonyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C20H23ClN2O5S	1
1	IC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0476027 Compound Info	2-[1-[4-(pyrimidine-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C23H16N4O4	1
1	IC50 = 290 nM Bioactivity Info	TI LI LO TS
CP0373094 Compound Info	2-{5-chloro-1'-[(2,3-difluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13ClF2N2O5	2
1	IC50 = 296 nM Bioactivity Info	TI LI LO TS
2	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0506218 Compound Info	2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H12ClFN2O4S	2
1	IC50 = 311 nM Bioactivity Info	TI LI LO TS
2	Ki = 158 nM Bioactivity Info	TI LI LO TS
CP0391851 Compound Info	2-[5-fluoro-1-(4-methoxyphenyl)sulfonyl-2-methylindol-3-yl]acetic acid Show/Hide	C18H16FNO5S	2
1	IC50 = 318 nM Bioactivity Info	TI LI LO TS
2	Ki = 299 nM Bioactivity Info	TI LI LO TS
CP0555897 Compound Info	2-[1-[4-(pyridazine-3-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C23H16N4O4	1
1	IC50 = 322 nM Bioactivity Info	TI LI LO TS
CP0420655 Compound Info	2-[1-(4-acetamidobenzoyl)isoquinolin-4-yl]acetic acid Show/Hide	C20H16N2O4	1
1	IC50 = 330 nM Bioactivity Info	TI LI LO TS
CP0387886 Compound Info	2-[1-[4-[(3,4-dichlorophenyl)sulfonylamino]benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C24H16Cl2N2O5S	1
1	IC50 = 340 nM Bioactivity Info	TI LI LO TS
CP0498416 Compound Info	2-(1-(3,4-dichlorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H12Cl2N2O4S	2
1	IC50 = 354 nM Bioactivity Info	TI LI LO TS
2	Ki = 52 nM Bioactivity Info	TI LI LO TS
CP0380032 Compound Info	2-[1-[4-(oxane-4-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid Show/Hide	C24H22N2O5	1
1	IC50 = 400 nM Bioactivity Info	TI LI LO TS
CP0103498 Compound Info	2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H15ClN2O5	2
1	IC50 = 418 nM Bioactivity Info	TI LI LO TS
2	Ki = 196 nM Bioactivity Info	TI LI LO TS
CP0209430 Compound Info	2-[1-[(4-chlorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H15ClN2O2	2
1	IC50 = 484 nM Bioactivity Info	TI LI LO TS
2	Ki = 149 nM Bioactivity Info	TI LI LO TS
CP0511435 Compound Info	2-(2-{[(3S)-4-(benzylsulfonyl)-3-methylpiperazin-1-yl]methyl}-4-chlorophenyl)-N-(methylsulfonyl)acetamide Show/Hide	C22H28ClN3O5S2	1
1	IC50 = 486 nM Bioactivity Info	TI LI LO TS
CP0461748 Compound Info	2-(2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-4-(trifluoromethyl)phenoxy)acetic acid Show/Hide	C20H21F3N2O5S	1
1	IC50 = 517 nM Bioactivity Info	TI LI LO TS
CP0473222 Compound Info	3-(4-Chloro-2-{[(3S)-3-methyl-4-(phenylacetyl)piperazin-1-yl]methyl}phenyl)propanoic acid Show/Hide	C23H27ClN2O3	1
1	IC50 = 547 nM Bioactivity Info	TI LI LO TS
CP0054113 Compound Info	2-[1-[(4-cyanophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H15N3O2	2
1	IC50 = 554 nM Bioactivity Info	TI LI LO TS
2	Ki = 379 nM Bioactivity Info	TI LI LO TS
CP0054110 Compound Info	2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H13ClN2O4S	2
1	IC50 = 565 nM Bioactivity Info	TI LI LO TS
2	Ki = 103 nM Bioactivity Info	TI LI LO TS
CP0498276 Compound Info	2-[5-fluoro-1-(3-fluorophenyl)sulfonyl-2-methylindol-3-yl]acetic acid Show/Hide	C17H13F2NO4S	2
1	IC50 = 639 nM Bioactivity Info	TI LI LO TS
2	Ki = 225 nM Bioactivity Info	TI LI LO TS
CP0456427 Compound Info	2-(1-butylsulfonyl-5-fluoro-2-methylindol-3-yl)acetic acid Show/Hide	C15H18FNO4S	2
1	IC50 = 842 nM Bioactivity Info	TI LI LO TS
2	Ki = 634 nM Bioactivity Info	TI LI LO TS
CP0378076 Compound Info	(1-Benzenesulfonyl-5-fluoro-2-methyl-1H-indol-3-yl)-acetic acid Show/Hide	C17H14FNO4S	2
1	IC50 = 987 nM Bioactivity Info	TI LI LO TS
2	Ki = 250 nM Bioactivity Info	TI LI LO TS
CP0405109 Compound Info	2-(4-chloro-2-((4-(2-phenylacetyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C21H23ClN2O4	1
1	IC50 = 1082 nM Bioactivity Info	TI LI LO TS
CP0503270 Compound Info	(S)-2-(4-chloro-2-((3-methyl-4-(phenylsulfonyl)piperazin-1-yl)methyl)phenoxy)-2-methylpropanoic acid Show/Hide	C22H27ClN2O5S	1
1	IC50 = 1442 nM Bioactivity Info	TI LI LO TS
CP0446446 Compound Info	2-[5-fluoro-2-methyl-1-(4-methylphenyl)sulfonylindol-3-yl]acetic acid Show/Hide	C18H16FNO4S	2
1	IC50 = 2184 nM Bioactivity Info	TI LI LO TS
2	Ki = 457 nM Bioactivity Info	TI LI LO TS
CP0503271 Compound Info	2-(4-chloro-2-(((3S,5R)-3,5-dimethyl-4-(2-phenylacetyl)piperazin-1-yl)methyl)phenoxy)acetic acid Show/Hide	C23H27ClN2O4	1
1	IC50 = 3840 nM Bioactivity Info	TI LI LO TS
CP0473223 Compound Info	2-(4-chloro-2-((4-(phenylsulfonyl)-1,4-diazepan-1-yl)methyl)phenoxy)acetic acid Show/Hide	C20H23ClN2O5S	1
1	IC50 = 4093 nM Bioactivity Info	TI LI LO TS
CP0485411 Compound Info	2-[1-(1,2-dimethylimidazol-4-yl)sulfonyl-5-fluoro-2-methylindol-3-yl]acetic acid Show/Hide	C16H16FN3O4S	2
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
2	Ki = 2979 nM Bioactivity Info	TI LI LO TS
CP0081955 Compound Info	Fevipiprant Show/Hide	C19H17F3N2O4S	2
1	Kd = 1.023 nM Bioactivity Info	TI LI LO TS
2	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0090559 Compound Info	2-[1-[(2-chloro-4-ethylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H19ClN2O4S	2
1	Kd = 1.905 nM Bioactivity Info	TI LI LO TS
2	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0323455 Compound Info	2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]indol-3-yl]acetic acid Show/Hide	C19H19NO4S	2
1	Kd = 25.12 nM Bioactivity Info	TI LI LO TS
2	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0490654 Compound Info	2-[(3S)-4-(4-chlorophenyl)sulfanyl-7-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid Show/Hide	C19H15ClFNO2S	1
1	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
CP0431188 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy]propanoic acid Show/Hide	C21H21ClO5S	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0382535 Compound Info	2-[2-[2-(4-acetamido-2-methyl-5-propylsulfonylphenyl)ethynyl]-4-chlorophenoxy]acetic acid Show/Hide	C22H22ClNO6S	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0456485 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-(2-methylpiperidin-1-yl)sulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C23H24ClNO5S	1
1	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0387495 Compound Info	2-[4-chloro-2-[2-(2-chloro-5-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H16Cl2O5S	1
1	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0550743 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]benzamide Show/Hide	C22H18FN5O3S	1
1	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CP0133930 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethyl)phenyl]methyl]pentanamide Show/Hide	C20H19F4N5O	1
1	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0550744 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-3-(4-methylphenyl)-N-[(4-methylsulfonylphenyl)methyl]propanamide Show/Hide	C25H24FN5O3S	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0475661 Compound Info	2-[4-chloro-2-[2-(2-chloro-5-propan-2-ylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H16Cl2O5S	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0418994 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-(2-methylpropylsulfonyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C21H21ClO5S	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0432740 Compound Info	2-[4-chloro-2-[2-(2-fluoro-5-propylsulfonylphenyl)ethynyl]phenoxy]propanoic acid Show/Hide	C20H18ClFO5S	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0410379 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(3-methoxyphenyl)methyl]pentanamide Show/Hide	C20H22FN5O2	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0550741 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methoxyphenyl)methyl]pentanamide Show/Hide	C20H22FN5O2	1
1	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0506094 Compound Info	2-[4-chloro-2-[2-[5-(dimethylsulfamoyl)-2-fluorophenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H15ClFNO5S	1
1	Ki = 3.1 nM Bioactivity Info	TI LI LO TS
CP0169837 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]propanamide Show/Hide	C18H18FN5O3S	1
1	Ki = 3.1 nM Bioactivity Info	TI LI LO TS
CP0495444 Compound Info	2-[4-chloro-2-[2-(3-methylsulfinylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C17H13ClO4S	1
1	Ki = 3.2 nM Bioactivity Info	TI LI LO TS
CP0392176 Compound Info	2-[4-chloro-2-[2-(2-fluoro-5-methylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C17H12ClFO5S	1
1	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0410377 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C21H22FN5O3	1
1	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0400876 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-(propan-2-ylsulfamoyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C20H20ClNO5S	1
1	Ki = 3.4 nM Bioactivity Info	TI LI LO TS
CP0456483 Compound Info	2-[4-chloro-2-[2-[5-(diethylsulfamoyl)-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C21H22ClNO5S	1
1	Ki = 3.4 nM Bioactivity Info	TI LI LO TS
CP0499401 Compound Info	2-[4-chloro-2-[2-(2-chloro-5-methylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C17H12Cl2O5S	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0520268 Compound Info	2-[4-chloro-2-[2-[4-(2-chlorophenyl)-3-methylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C23H16Cl2O5S	1
1	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0393378 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-morpholin-4-ylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C21H20ClNO6S	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0456416 Compound Info	2-[4-chloro-2-[2-[5-(2-methoxyethylsulfamoyl)-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C20H20ClNO6S	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0387496 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-[methyl(propan-2-yl)sulfamoyl]phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C21H22ClNO5S	1
1	Ki = 3.8 nM Bioactivity Info	TI LI LO TS
CP0427437 Compound Info	2-[4-chloro-2-[2-(2-fluoro-5-propan-2-ylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H16ClFO5S	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0410380 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]pyridine-3-carboxamide Show/Hide	C21H17FN6O3S	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0081954 Compound Info	2-[1-[(2-chloro-4-methylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H17ClN2O4S	1
1	Ki = 4 nM Bioactivity Info	TI LI LO TS
CP0387497 Compound Info	2-[4-chloro-2-[2-[5-[2-methoxyethyl(methyl)sulfamoyl]-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C21H22ClNO6S	1
1	Ki = 4.1 nM Bioactivity Info	TI LI LO TS
CP0456484 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-[methyl(2-methylpropyl)sulfamoyl]phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C22H24ClNO5S	1
1	Ki = 4.2 nM Bioactivity Info	TI LI LO TS
CP0427150 Compound Info	2-[4-chloro-2-[2-(4-propylpyridin-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C18H16ClNO3	1
1	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0459329 Compound Info	2-[4-chloro-2-[2-[5-(ethylsulfamoyl)-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C19H18ClNO5S	1
1	Ki = 4.4 nM Bioactivity Info	TI LI LO TS
CP0139383 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[[3-(trifluoromethoxy)phenyl]methyl]pentanamide Show/Hide	C20H19F4N5O2	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0476266 Compound Info	2-[4-chloro-2-[2-(5-methylsulfonyl-2-propan-2-ylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C20H19ClO5S	1
1	Ki = 4.6 nM Bioactivity Info	TI LI LO TS
CP0495977 Compound Info	2-[4-chloro-2-[2-[4-(2-methylpropyl)pyridin-3-yl]ethynyl]phenoxy]acetic acid Show/Hide	C19H18ClNO3	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0502868 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]butanamide Show/Hide	C20H20FN5O3	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0382594 Compound Info	2-[4-chloro-2-[2-(3-methylsulfonyl-4-phenylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C23H17ClO5S	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0387449 Compound Info	2-[4-chloro-2-[2-[5-(dimethylsulfamoyl)-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C19H18ClNO5S	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0392175 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-methylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C18H15ClO5S	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0401043 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(5-methoxypyridin-2-yl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C28H30N2O5	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0418996 Compound Info	2-[2-[2-(5-benzylsulfonyl-2-methylphenyl)ethynyl]-4-chlorophenoxy]acetic acid Show/Hide	C24H19ClO5S	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0432585 Compound Info	2-[2-[2-[5-(tert-butylsulfamoyl)-2-methylphenyl]ethynyl]-4-chlorophenoxy]acetic acid Show/Hide	C21H22ClNO5S	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0523751 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-piperidin-1-ylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C22H22ClNO5S	1
1	Ki = 5 nM Bioactivity Info	TI LI LO TS
CP0416091 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethylsulfonyl)phenyl]methyl]propanamide Show/Hide	C18H15F4N5O3S	1
1	Ki = 5.2 nM Bioactivity Info	TI LI LO TS
CP0509741 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]-3-methylbutanamide Show/Hide	C21H22FN5O3	1
1	Ki = 5.6 nM Bioactivity Info	TI LI LO TS
CP0392177 Compound Info	2-[2-[2-[5-(benzenesulfonyl)-2-methylphenyl]ethynyl]-4-chlorophenoxy]acetic acid Show/Hide	C23H17ClO5S	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0461787 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-propan-2-ylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C20H19ClO5S	1
1	Ki = 6 nM Bioactivity Info	TI LI LO TS
CP0123607 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(3-propan-2-yloxyphenyl)methyl]propanamide Show/Hide	C20H22FN5O2	1
1	Ki = 6.4 nM Bioactivity Info	TI LI LO TS
CP0066163 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethoxy)phenyl]methyl]propanamide Show/Hide	C18H15F4N5O2	1
1	Ki = 6.9 nM Bioactivity Info	TI LI LO TS
CP0382533 Compound Info	2-[4-chloro-2-[2-[4-(4-methoxyphenyl)-3-methylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C24H19ClO6S	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0463234 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-(2-phenylethylsulfonyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C25H21ClO5S	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0475227 Compound Info	2-[4-cyano-2-[2-(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C21H19NO5S	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0112127 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[3-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C21H23N5O3	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0424659 Compound Info	2-[5'-chloro-1-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)methyl]-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C23H17ClN4O6	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0445485 Compound Info	2-[1-[[4-ethylsulfonyl-2-(trifluoromethyl)phenyl]methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C20H19F3N2O4S	1
1	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0432885 Compound Info	N-(1-benzofuran-2-ylmethyl)-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C21H20FN5O2	1
1	Ki = 7.1 nM Bioactivity Info	TI LI LO TS
CP0432881 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methoxyphenyl)methyl]propanamide Show/Hide	C18H18FN5O2	1
1	Ki = 7.6 nM Bioactivity Info	TI LI LO TS
CP0066159 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethoxy)phenyl]methyl]pentanamide Show/Hide	C20H19F4N5O2	1
1	Ki = 7.7 nM Bioactivity Info	TI LI LO TS
CP0382534 Compound Info	2-[4-chloro-2-[2-[4-(3-methoxyphenyl)-3-methylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C24H19ClO6S	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0392178 Compound Info	2-[4-chloro-2-[2-[5-(3-hydroxypropylsulfonyl)-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C20H19ClO6S	1
1	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0505975 Compound Info	2-[4-chloro-2-[2-(5-methylsulfonyl-2-propylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C20H19ClO5S	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0520243 Compound Info	2-[4-chloro-2-[2-(5-ethylsulfonyl-2-methylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H17ClO5S	1
1	Ki = 8.6 nM Bioactivity Info	TI LI LO TS
CP0392174 Compound Info	2-[4-chloro-2-[2-(3-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H17ClO5S	1
1	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0427151 Compound Info	2-[4-chloro-2-[2-[3-(2-hydroxyethylsulfonyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H15ClO6S	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0456565 Compound Info	2-[2-[2-(3-propylsulfonylphenyl)ethynyl]-4-(trifluoromethyl)phenoxy]acetic acid Show/Hide	C20H17F3O5S	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0463236 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-(methylsulfamoyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H16ClNO5S	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0415474 Compound Info	N-[(3-ethynylphenyl)methyl]-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C21H20FN5O	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0542406 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C19H18FN5O3	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0394532 Compound Info	2-{5-chloro-1'-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C22H20ClN3O6	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0390764 Compound Info	2-[4-cyano-2-[2-(5-methylsulfonyl-2-propan-2-ylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C21H19NO5S	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0391011 Compound Info	2-[4-chloro-2-[2-(5,5-dioxodibenzothiophen-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C22H13ClO5S	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0401044 Compound Info	2-[2-[2-(2-chlorophenyl)ethynyl]-4-(trifluoromethyl)phenoxy]acetic acid Show/Hide	C17H10ClF3O3	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0505929 Compound Info	2-[2-[2-(3-propylsulfonylphenyl)ethynyl]-3-thiophen-2-ylphenoxy]acetic acid Show/Hide	C23H20O5S2	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0470516 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[3-(2H-tetrazol-5-yl)phenyl]butanamide Show/Hide	C20H21N5O3	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0373107 Compound Info	2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,5'-dione]acetic acid Show/Hide	C20H15Cl2FN2O4	1
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0524931 Compound Info	2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,5'-dione]acetic acid Show/Hide	C20H15Cl2FN2O4	2
1	Ki = 13 nM Bioactivity Info	TI LI LO TS
2	Ki = 683 nM Bioactivity Info	TI LI LO TS
CP0382595 Compound Info	2-[4-chloro-2-[2-[4-(4-chlorophenyl)-3-methylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C23H16Cl2O5S	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0482210 Compound Info	2-[4-chloro-2-[2-[3-(dimethylsulfamoyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H16ClNO5S	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0525014 Compound Info	2-[2-[2-(2-tert-butyl-1,1,3-trioxo-1,2-benzothiazol-6-yl)ethynyl]-4-chlorophenoxy]acetic acid Show/Hide	C21H18ClNO6S	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0395105 Compound Info	2-[4-chloro-2-[2-(3-methylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C17H13ClO5S	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0494026 Compound Info	2-[(4S)-5'-chloro-1-[(5-chloro-2-fluorophenyl)methyl]-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C19H12Cl2FN3O5	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0523749 Compound Info	2-[4-chloro-2-[2-[4-(3-chlorophenyl)-3-methylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C23H16Cl2O5S	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0566443 Compound Info	2-[5'-chloro-3-methyl-2,2',5-trioxo-1-[(2-phenyl-1,3-thiazol-4-yl)methyl]spiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C23H17ClN4O5S	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0525027 Compound Info	2-[4-chloro-2-[2-(4-methyl-1-oxidopyridin-1-ium-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C16H12ClNO4	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0415478 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-2-methyl-N-[(4-methylsulfonylphenyl)methyl]propanamide Show/Hide	C19H20FN5O3S	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0550745 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]pyridine-4-carboxamide Show/Hide	C21H17FN6O3S	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0459218 Compound Info	2-[2-[2-(3-propylsulfonylphenyl)ethynyl]-3-thiophen-3-ylphenoxy]acetic acid Show/Hide	C23H20O5S2	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0470515 Compound Info	N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-(naphthalen-2-ylmethyl)pentanamide Show/Hide	C23H22FN5O	1
1	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0394818 Compound Info	2-[4-chloro-2-[2-[5-(methanesulfonamido)pyridin-3-yl]ethynyl]phenoxy]acetic acid Show/Hide	C16H13ClN2O5S	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0395108 Compound Info	2-[3-phenyl-2-[2-(3-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C25H22O5S	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0520245 Compound Info	2-[4-chloro-2-[2-[5-(2-hydroxyethylsulfonyl)-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C19H17ClO6S	1
1	Ki = 19 nM Bioactivity Info	TI LI LO TS
CP0210131 Compound Info	2-(2-cyclohexyl-4-(trifluoromethyl)phenoxy)acetic acid Show/Hide	C15H17F3O3	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0513855 Compound Info	2-{5-chloro-1'-[(3-chloro-5-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13Cl2FN2O5	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0513856 Compound Info	2-{5-chloro-1'-[(2,5-difluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13ClF2N2O5	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0461782 Compound Info	2-[4-cyano-2-[2-(3-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C20H17NO5S	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0505954 Compound Info	2-[4-chloro-2-[2-(3-methoxy-2,2-dimethyl-1,1-dioxo-3H-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C21H19ClO6S	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0525028 Compound Info	2-[4-chloro-2-[2-[2-methyl-5-(4-methylpiperazin-1-yl)sulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C22H23ClN2O5S	1
1	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0393375 Compound Info	2-[4-chloro-2-[2-[2-fluoro-4-(methoxymethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H14ClFO4	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0550742 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-hydroxyphenyl)methyl]propanamide Show/Hide	C17H16FN5O2	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0109471 Compound Info	2-[(3R)-5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H14ClFN2O5	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0433274 Compound Info	2-[4-chloro-2-[2-(1,1-dioxo-2,3-dihydro-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C18H13ClO5S	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0484561 Compound Info	2-[2-[2-(2-chlorophenyl)ethynyl]-4-cyanophenoxy]acetic acid Show/Hide	C17H10ClNO3	1
1	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0505933 Compound Info	2-[4-chloro-2-[2-[2-(trifluoromethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C17H10ClF3O3	1
1	Ki = 24 nM Bioactivity Info	TI LI LO TS
CP0395104 Compound Info	2-[4-chloro-2-[2-(4-methylpyridin-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C16H12ClNO3	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0433273 Compound Info	2-[4-chloro-2-[2-(1,1-dioxo-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C18H11ClO5S	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0433275 Compound Info	2-[4-chloro-2-[2-(3-methoxy-2,2,3-trimethyl-1,1-dioxo-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C22H21ClO6S	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0266551 Compound Info	2-[4-chloro-2-[2-(2-chlorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H10Cl2O3	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0390880 Compound Info	2-[4-chloro-2-[2-[3-(3-hydroxypropylsulfonyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C19H17ClO6S	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0432741 Compound Info	2-[4-chloro-2-[2-[2-fluoro-4-(hydroxymethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C17H12ClFO4	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0525015 Compound Info	2-[4-chloro-2-[2-(3-hydroxy-2,2,3-trimethyl-1,1-dioxo-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C21H19ClO6S	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0509733 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-[(4-methylsulfonylphenyl)methyl]oxane-4-carboxamide Show/Hide	C21H22FN5O4S	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0424658 Compound Info	2-[5'-chloro-1-[(5-chloro-2-fluorophenyl)methyl]-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C19H12Cl2FN3O5	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0147599 Compound Info	2-[1-[[2,4-bis(trifluoromethyl)phenyl]methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H14F6N2O2	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0503079 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy]butanoic acid Show/Hide	C22H23ClO5S	1
1	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0393371 Compound Info	2-[4-chloro-2-[2-(2,2-dimethyl-1,1,3-trioxo-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C20H15ClO6S	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0246918 Compound Info	2-[2-methyl-1-[(2-methyl-4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H20N2O4S	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0248457 Compound Info	2-[2-methyl-1-[[4-methylsulfonyl-3-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H17F3N2O4S	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0427736 Compound Info	2-{5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,5'-dione}acetic acid Show/Hide	C20H15Cl2FN2O4	1
1	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0520267 Compound Info	2-[4-chloro-2-[2-(3-hydroxy-2,2-dimethyl-1,1-dioxo-3H-1-benzothiophen-6-yl)ethynyl]phenoxy]acetic acid Show/Hide	C20H17ClO6S	1
1	Ki = 33 nM Bioactivity Info	TI LI LO TS
CP0140521 Compound Info	2-[(4S)-5'-chloro-1-[(5-chloro-2-fluorophenyl)methyl]-3-methyl-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C20H14Cl2FN3O5	1
1	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0478153 Compound Info	2-{5-chloro-1'-[(3,5-difluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13ClF2N2O5	1
1	Ki = 37 nM Bioactivity Info	TI LI LO TS
CP0392179 Compound Info	2-[4-chloro-2-[2-[5-(dimethylsulfamoyl)pyridin-3-yl]ethynyl]phenoxy]acetic acid Show/Hide	C17H15ClN2O5S	1
1	Ki = 37 nM Bioactivity Info	TI LI LO TS
CP0450684 Compound Info	N-(naphthalen-2-ylmethyl)-N-[3-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C23H23N5O	1
1	Ki = 39 nM Bioactivity Info	TI LI LO TS
CP0427149 Compound Info	2-[4-chloro-2-[2-[2-fluoro-3-(hydroxymethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C17H12ClFO4	1
1	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0461409 Compound Info	2-[4-chloro-2-[2-[5-(dimethylsulfamoyl)-2-methylpyridin-3-yl]ethynyl]phenoxy]acetic acid Show/Hide	C18H17ClN2O5S	1
1	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0524904 Compound Info	2-[4-chloro-2-[2-(5-morpholin-4-ylsulfonylpyridin-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C19H17ClN2O6S	1
1	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0542405 Compound Info	N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C19H19N5O3	1
1	Ki = 42 nM Bioactivity Info	TI LI LO TS
CP0435020 Compound Info	2-{5-chloro-1'-[(2-chloro-5-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13Cl2FN2O5	1
1	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0523750 Compound Info	2-[4-chloro-2-[2-(4-hexylpyridin-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C21H22ClNO3	1
1	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0525016 Compound Info	2-[4-chloro-2-[2-[3-methylsulfonyl-4-[4-(trifluoromethyl)phenyl]phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C24H16ClF3O5S	1
1	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0520269 Compound Info	2-[1-[2-(3-propylsulfonylphenyl)ethynyl]naphthalen-2-yl]oxyacetic acid Show/Hide	C23H20O5S	1
1	Ki = 44 nM Bioactivity Info	TI LI LO TS
CP0416073 Compound Info	N-[(3-methoxyphenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C20H23N5O2	1
1	Ki = 44 nM Bioactivity Info	TI LI LO TS
CP0470517 Compound Info	N-[2,4-difluoro-5-(2H-tetrazol-5-yl)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)pentanamide Show/Hide	C21H21F2N5O3	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0372522 Compound Info	2-[4-chloro-2-[2-[4-(diethylcarbamoyl)-3-propan-2-ylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C24H26ClNO6S	1
1	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0482209 Compound Info	2-[4-chloro-2-[2-(2-fluorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H10ClFO3	1
1	Ki = 47 nM Bioactivity Info	TI LI LO TS
CP0106923 Compound Info	2-[6-ethyl-2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C20H22N2O4S	1
1	Ki = 47 nM Bioactivity Info	TI LI LO TS
CP0506312 Compound Info	2-(2-methyl-1-(4-nitrophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H13N3O6S	1
1	Ki = 48 nM Bioactivity Info	TI LI LO TS
CP0495937 Compound Info	2-[4-chloro-2-[2-[3-(methylsulfonylmethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H15ClO5S	1
1	Ki = 48 nM Bioactivity Info	TI LI LO TS
CP0010057 Compound Info	2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid Show/Hide	C19H16ClNO4	2
1	Ki = 50 nM Bioactivity Info	TI LI LO TS
2	Ki = 8000 nM Bioactivity Info	TI LI LO TS
CP0066161 Compound Info	N-[(4-methoxyphenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C20H23N5O2	1
1	Ki = 50 nM Bioactivity Info	TI LI LO TS
CP0248458 Compound Info	2-[1-[(4-ethylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H20N2O4S	1
1	Ki = 50 nM Bioactivity Info	TI LI LO TS
CP0495936 Compound Info	2-[4-chloro-2-[2-[3-(dimethylcarbamoyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C19H16ClNO4	1
1	Ki = 52 nM Bioactivity Info	TI LI LO TS
CP0467402 Compound Info	2-[4-chloro-2-[2-[3-(methanesulfonamido)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C17H14ClNO5S	1
1	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0484562 Compound Info	2-[3-(2,4-dimethyl-1,3-thiazol-5-yl)-2-[2-(3-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C24H23NO5S2	1
1	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0516323 Compound Info	2-(5-chloro-1'-{[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione)acetic acid Show/Hide	C23H15Cl2N3O5S	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0393374 Compound Info	2-[3-chloro-2-[2-(3-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H17ClO5S	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0520248 Compound Info	2-[4-chloro-2-[2-[4-(dimethylcarbamoyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C19H16ClNO4	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0443960 Compound Info	N-[3-fluoro-5-(2H-tetrazol-5-yl)phenyl]-N-(quinolin-2-ylmethyl)propanamide Show/Hide	C20H17FN6O	1
1	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0461784 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy]pentanoic acid Show/Hide	C23H25ClO5S	1
1	Ki = 57 nM Bioactivity Info	TI LI LO TS
CP0390878 Compound Info	2-[4-chloro-2-[2-(4-chlorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H10Cl2O3	1
1	Ki = 60 nM Bioactivity Info	TI LI LO TS
CP0432586 Compound Info	2-[4-chloro-2-[2-(5-methylsulfonylpyridin-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C16H12ClNO5S	1
1	Ki = 60 nM Bioactivity Info	TI LI LO TS
CP0382596 Compound Info	2-[4-chloro-2-[2-[4-(dimethylcarbamoyl)-3-propan-2-ylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C22H22ClNO6S	1
1	Ki = 65 nM Bioactivity Info	TI LI LO TS
CP0433276 Compound Info	2-[4-fluoro-2-[2-(3-propylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C19H17FO5S	1
1	Ki = 65 nM Bioactivity Info	TI LI LO TS
CP0506254 Compound Info	N-[(4-methylsulfonylphenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C18H19N5O3S	1
1	Ki = 69 nM Bioactivity Info	TI LI LO TS
CP0373089 Compound Info	2-[(3R)-5-chloro-1'-[(3-methoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C21H17ClN2O6	1
1	Ki = 72 nM Bioactivity Info	TI LI LO TS
CP0495976 Compound Info	2-[4-chloro-2-[2-[2-fluoro-5-(methoxymethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H14ClFO4	1
1	Ki = 72 nM Bioactivity Info	TI LI LO TS
CP0081956 Compound Info	2-[2,6-dimethyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H20N2O4S	1
1	Ki = 72 nM Bioactivity Info	TI LI LO TS
CP0427148 Compound Info	2-[4-chloro-2-[2-[2-fluoro-5-(hydroxymethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C17H12ClFO4	1
1	Ki = 73 nM Bioactivity Info	TI LI LO TS
CP0328153 Compound Info	(S)-2-(4-chloro-2-cyclohexylphenoxy)propanoic acid Show/Hide	C15H19ClO3	1
1	Ki = 75 nM Bioactivity Info	TI LI LO TS
CP0505200 Compound Info	2-[(3R)-1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H15ClN2O5	1
1	Ki = 81 nM Bioactivity Info	TI LI LO TS
CP0311206 Compound Info	2-(4-bromo-2-cyclohexylphenoxy)acetic acid Show/Hide	C14H17BrO3	1
1	Ki = 83 nM Bioactivity Info	TI LI LO TS
CP0520246 Compound Info	2-[4-chloro-2-[2-(4-methylsulfonylphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C17H13ClO5S	1
1	Ki = 86 nM Bioactivity Info	TI LI LO TS
CP0147600 Compound Info	2-[2-methyl-1-[(4-propan-2-ylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C20H22N2O4S	1
1	Ki = 86 nM Bioactivity Info	TI LI LO TS
CP0456493 Compound Info	2-[4-chloro-2-[2-[4-(morpholine-4-carbonyl)-3-propan-2-ylsulfonylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C24H24ClNO7S	1
1	Ki = 87 nM Bioactivity Info	TI LI LO TS
CP0478146 Compound Info	2-{5-chloro-1'-[(3,4-difluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H13ClF2N2O5	1
1	Ki = 89 nM Bioactivity Info	TI LI LO TS
CP0309152 Compound Info	2-(4-chloro-2-(1-methylcyclohexyl)phenoxy)acetic acid Show/Hide	C15H19ClO3	1
1	Ki = 90 nM Bioactivity Info	TI LI LO TS
CP0522139 Compound Info	2-[4-chloro-2-[2-[3-(trifluoromethyl)phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C17H10ClF3O3	1
1	Ki = 92 nM Bioactivity Info	TI LI LO TS
CP0424660 Compound Info	2-[5'-chloro-1-[(1,3-diphenylpyrazol-4-yl)methyl]-3-methyl-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C29H22ClN5O5	1
1	Ki = 96 nM Bioactivity Info	TI LI LO TS
CP0309153 Compound Info	(3-cyclohexyl-4'-fluoro-biphenyl-4-yloxy)-acetic acid Show/Hide	C20H21FO3	1
1	Ki = 99 nM Bioactivity Info	TI LI LO TS
CP0505965 Compound Info	2-[4-chloro-2-[2-(2,4-difluorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H9ClF2O3	1
1	Ki = 101 nM Bioactivity Info	TI LI LO TS
CP0459328 Compound Info	2-[4-chloro-2-(2-phenylethynyl)phenoxy]acetic acid Show/Hide	C16H11ClO3	1
1	Ki = 108 nM Bioactivity Info	TI LI LO TS
CP0542924 Compound Info	2-[1-[(3,4-dichlorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H14Cl2N2O2	1
1	Ki = 109 nM Bioactivity Info	TI LI LO TS
CP0066160 Compound Info	N-[3-(2H-tetrazol-5-yl)phenyl]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide Show/Hide	C18H16F3N5O	1
1	Ki = 110 nM Bioactivity Info	TI LI LO TS
CP0482094 Compound Info	2-[(4S)-5'-chloro-1-[(5-chloro-2-fluorophenyl)methyl]-2,2',5-trioxo-3-propylspiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C22H18Cl2FN3O5	1
1	Ki = 110 nM Bioactivity Info	TI LI LO TS
CP0566442 Compound Info	2-[5'-chloro-3-methyl-1-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)methyl]-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C24H19ClN4O6	1
1	Ki = 110 nM Bioactivity Info	TI LI LO TS
CP0539703 Compound Info	2-{5-chloro-1'-[(4-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H14Cl2N2O5	1
1	Ki = 115 nM Bioactivity Info	TI LI LO TS
CP0390879 Compound Info	2-[4-chloro-2-(2-pyridin-3-ylethynyl)phenoxy]acetic acid Show/Hide	C15H10ClNO3	1
1	Ki = 117 nM Bioactivity Info	TI LI LO TS
CP0418998 Compound Info	2-[4-chloro-2-[2-[3-[methyl(methylsulfonyl)amino]phenyl]ethynyl]phenoxy]acetic acid Show/Hide	C18H16ClNO5S	1
1	Ki = 122 nM Bioactivity Info	TI LI LO TS
CP0416074 Compound Info	N-(1,3-benzodioxol-5-ylmethyl)-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C18H17N5O3	1
1	Ki = 130 nM Bioactivity Info	TI LI LO TS
CP0470512 Compound Info	N-[(3-ethynylphenyl)methyl]-N-[2-fluoro-5-(2H-tetrazol-5-yl)phenyl]acetamide Show/Hide	C18H14FN5O	1
1	Ki = 140 nM Bioactivity Info	TI LI LO TS
CP0427743 Compound Info	2-{5-chloro-1'-[(4-phenoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C26H19ClN2O6	1
1	Ki = 143 nM Bioactivity Info	TI LI LO TS
CP0495934 Compound Info	2-[4-chloro-2-[2-(2-methylpyridin-3-yl)ethynyl]phenoxy]acetic acid Show/Hide	C16H12ClNO3	1
1	Ki = 143 nM Bioactivity Info	TI LI LO TS
CP0447845 Compound Info	2-[2-methyl-1-[[4-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H15F3N2O2	1
1	Ki = 145 nM Bioactivity Info	TI LI LO TS
CP0201721 Compound Info	2-(4-chloro-2-cyclopentylphenoxy)acetic acid Show/Hide	C13H15ClO3	1
1	Ki = 150 nM Bioactivity Info	TI LI LO TS
CP0315423 Compound Info	2-(4-chloro-2-cyclohexylphenoxy)acetic acid Show/Hide	C14H17ClO3	1
1	Ki = 154 nM Bioactivity Info	TI LI LO TS
CP0422076 Compound Info	2-{5-chloro-1'-[(3-fluoro-4-methoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C21H16ClFN2O6	1
1	Ki = 154 nM Bioactivity Info	TI LI LO TS
CP0427744 Compound Info	2-{5-chloro-1'-[(3-methoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C21H17ClN2O6	1
1	Ki = 169 nM Bioactivity Info	TI LI LO TS
CP0427147 Compound Info	2-[4-chloro-2-[2-(5-chlorothiophen-2-yl)ethynyl]phenoxy]acetic acid Show/Hide	C14H8Cl2O3S	1
1	Ki = 183 nM Bioactivity Info	TI LI LO TS
CP0467398 Compound Info	2-[4-chloro-2-[2-(2-methoxyphenyl)ethynyl]phenoxy]acetic acid Show/Hide	C17H13ClO4	1
1	Ki = 190 nM Bioactivity Info	TI LI LO TS
CP0427739 Compound Info	2-(5-chloro-1'-{[5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]methyl}-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione)acetic acid Show/Hide	C23H17ClN4O7	1
1	Ki = 212 nM Bioactivity Info	TI LI LO TS
CP0066157 Compound Info	N-[3-(2H-tetrazol-5-yl)phenyl]-N-[[3-(trifluoromethyl)phenyl]methyl]propanamide Show/Hide	C18H16F3N5O	1
1	Ki = 220 nM Bioactivity Info	TI LI LO TS
CP0415475 Compound Info	N-[(4-methoxyphenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C18H19N5O2	1
1	Ki = 220 nM Bioactivity Info	TI LI LO TS
CP0349972 Compound Info	2-(4-cyano-2-cyclohexylphenoxy)acetic acid Show/Hide	C15H17NO3	1
1	Ki = 230 nM Bioactivity Info	TI LI LO TS
CP0412552 Compound Info	2-{5-chloro-1'-[(2-methoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C21H17ClN2O6	1
1	Ki = 233 nM Bioactivity Info	TI LI LO TS
CP0441090 Compound Info	2-[2-[[4-chloro-2-(1,2-oxazol-5-yl)phenoxy]methyl]phenoxy]acetic acid Show/Hide	C18H14ClNO5	1
1	Ki = 247 nM Bioactivity Info	TI LI LO TS
CP0484563 Compound Info	2-[4-chloro-2-[2-(2-fluoro-5-propylsulfonylphenyl)ethynyl]phenoxy]-2-methylpropanoic acid Show/Hide	C21H20ClFO5S	1
1	Ki = 260 nM Bioactivity Info	TI LI LO TS
CP0426682 Compound Info	2-[(4S)-5'-chloro-1-[(5-chloro-2-fluorophenyl)methyl]-3-ethyl-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C21H16Cl2FN3O5	1
1	Ki = 260 nM Bioactivity Info	TI LI LO TS
CP0435022 Compound Info	2-[5-chloro-1'-(2-phenylethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C21H17ClN2O5	1
1	Ki = 267 nM Bioactivity Info	TI LI LO TS
CP0554499 Compound Info	2-[1-[(3-chlorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H15ClN2O2	1
1	Ki = 270 nM Bioactivity Info	TI LI LO TS
CP0471155 Compound Info	2-[1-[(3,4-difluorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H14F2N2O2	1
1	Ki = 278 nM Bioactivity Info	TI LI LO TS
CP0462755 Compound Info	2-[5'-chloro-1-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-3-methyl-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C22H21ClN4O6	1
1	Ki = 280 nM Bioactivity Info	TI LI LO TS
CP0524692 Compound Info	2-(2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H14N2O4S	1
1	Ki = 282 nM Bioactivity Info	TI LI LO TS
CP0533191 Compound Info	2-[2-[2-(2-chlorophenyl)ethynyl]-4-methylphenoxy]acetic acid Show/Hide	C17H13ClO3	1
1	Ki = 283 nM Bioactivity Info	TI LI LO TS
CP0400686 Compound Info	2-[4-chloro-2-[2-[5-[3-(dimethylamino)propyl-methylsulfamoyl]-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C23H27ClN2O5S	1
1	Ki = 287 nM Bioactivity Info	TI LI LO TS
CP0520266 Compound Info	2-[4-chloro-2-[2-[5-(2-hydroxyethylsulfamoyl)pyridin-3-yl]ethynyl]phenoxy]acetic acid Show/Hide	C17H15ClN2O6S	1
1	Ki = 301 nM Bioactivity Info	TI LI LO TS
CP0507927 Compound Info	2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H13Cl2FN2O5	1
1	Ki = 302 nM Bioactivity Info	TI LI LO TS
CP0519728 Compound Info	2-[2-methyl-1-[(4-methylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H18N2O2	1
1	Ki = 302 nM Bioactivity Info	TI LI LO TS
CP0157437 Compound Info	2-(2-cyclohexylphenoxy)acetic acid Show/Hide	C14H18O3	1
1	Ki = 311 nM Bioactivity Info	TI LI LO TS
CP0435019 Compound Info	2-[5-chloro-1'-(furan-3-ylmethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C18H13ClN2O6	1
1	Ki = 318 nM Bioactivity Info	TI LI LO TS
CP0517468 Compound Info	N-(isoquinolin-6-ylmethyl)-N-[3-(2H-tetrazol-5-yl)phenyl]pentanamide Show/Hide	C22H22N6O	1
1	Ki = 330 nM Bioactivity Info	TI LI LO TS
CP0542586 Compound Info	2-[2-methyl-6-[[2-(propylcarbamoyl)phenoxy]methyl]phenoxy]acetic acid Show/Hide	C20H23NO5	1
1	Ki = 333 nM Bioactivity Info	TI LI LO TS
CP0315424 Compound Info	2-(2-cyclohexyl-4-methylphenoxy)acetic acid Show/Hide	C15H20O3	1
1	Ki = 353 nM Bioactivity Info	TI LI LO TS
CP0394565 Compound Info	2-[5-chloro-1'-(1-phenylethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C21H17ClN2O5	1
1	Ki = 356 nM Bioactivity Info	TI LI LO TS
CP0406725 Compound Info	2-[4-chloro-2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H17ClN2O4S	1
1	Ki = 356 nM Bioactivity Info	TI LI LO TS
CP0410378 Compound Info	N-[(3-methoxyphenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C18H19N5O2	1
1	Ki = 360 nM Bioactivity Info	TI LI LO TS
CP0495935 Compound Info	2-[4-chloro-2-[2-[5-[2-(dimethylamino)ethyl-methylsulfamoyl]-2-methylphenyl]ethynyl]phenoxy]acetic acid Show/Hide	C22H25ClN2O5S	1
1	Ki = 369 nM Bioactivity Info	TI LI LO TS
CP0497381 Compound Info	2-(1-(3-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H13ClN2O4S	1
1	Ki = 377 nM Bioactivity Info	TI LI LO TS
CP0459324 Compound Info	2-[4-chloro-2-[2-[5-[methyl(methylsulfonyl)amino]pyridin-3-yl]ethynyl]phenoxy]acetic acid Show/Hide	C17H15ClN2O5S	1
1	Ki = 378 nM Bioactivity Info	TI LI LO TS
CP0549623 Compound Info	2-[5'-chloro-1-[(2-fluorophenyl)methyl]-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C19H13ClFN3O5	1
1	Ki = 390 nM Bioactivity Info	TI LI LO TS
CP0549718 Compound Info	2-[5'-chloro-1-[(2,5-difluorophenyl)methyl]-3-methyl-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C20H14ClF2N3O5	1
1	Ki = 390 nM Bioactivity Info	TI LI LO TS
CP0427737 Compound Info	2-[5-chloro-1'-(1,3-oxazol-2-ylmethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C17H12ClN3O6	1
1	Ki = 438 nM Bioactivity Info	TI LI LO TS
CP0467222 Compound Info	2-(2-cyclohexyl-4-fluorophenoxy)acetic acid Show/Hide	C14H17FO3	1
1	Ki = 446 nM Bioactivity Info	TI LI LO TS
CP0460790 Compound Info	2-[5'-chloro-3-methyl-2,2',5-trioxo-1-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]spiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C20H19ClN4O5S	1
1	Ki = 490 nM Bioactivity Info	TI LI LO TS
CP0416361 Compound Info	2-[2-[(2-methylquinolin-8-yl)oxymethyl]phenoxy]acetic acid Show/Hide	C19H17NO4	1
1	Ki = 492 nM Bioactivity Info	TI LI LO TS
CP0505202 Compound Info	2-{5-chloro-1'-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C19H15ClN4O5S	1
1	Ki = 497 nM Bioactivity Info	TI LI LO TS
CP0379871 Compound Info	2-[1-[(4-methoxyphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H18N2O3	1
1	Ki = 504 nM Bioactivity Info	TI LI LO TS
CP0499400 Compound Info	2-[4-chloro-2-[2-(2-methyl-5-propylsulfonylphenyl)ethynyl]phenoxy]-4-methylpentanoic acid Show/Hide	C24H27ClO5S	1
1	Ki = 515 nM Bioactivity Info	TI LI LO TS
CP0416363 Compound Info	2-[2-[(5-chloro-2-methylphenoxy)methyl]phenoxy]acetic acid Show/Hide	C16H15ClO4	1
1	Ki = 520 nM Bioactivity Info	TI LI LO TS
CP0494063 Compound Info	2-[1-[(3-bromophenyl)methyl]-3,5-diethylpyrazol-4-yl]acetic acid Show/Hide	C16H19BrN2O2	1
1	Ki = 563 nM Bioactivity Info	TI LI LO TS
CP0549230 Compound Info	2-[3,5-diethyl-1-(naphthalen-2-ylmethyl)pyrazol-4-yl]acetic acid Show/Hide	C20H22N2O2	1
1	Ki = 574 nM Bioactivity Info	TI LI LO TS
CP0432884 Compound Info	N-[(3-methylphenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C18H19N5O	1
1	Ki = 580 nM Bioactivity Info	TI LI LO TS
CP0541839 Compound Info	2-(1-benzyl-2-methylpyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H16N2O2	1
1	Ki = 588 nM Bioactivity Info	TI LI LO TS
CP0525264 Compound Info	2-[2-[(2-cyclopropyl-4-fluorophenoxy)methyl]phenoxy]acetic acid Show/Hide	C18H17FO4	1
1	Ki = 591 nM Bioactivity Info	TI LI LO TS
CP0529887 Compound Info	2-[5-chloro-1'-(1H-indol-3-ylmethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C22H16ClN3O5	1
1	Ki = 596 nM Bioactivity Info	TI LI LO TS
CP0418993 Compound Info	2-[4-chloro-2-(2-pyridin-4-ylethynyl)phenoxy]acetic acid Show/Hide	C15H10ClNO3	1
1	Ki = 601 nM Bioactivity Info	TI LI LO TS
CP0498415 Compound Info	2-(2-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H16N2O4S	1
1	Ki = 619 nM Bioactivity Info	TI LI LO TS
CP0470513 Compound Info	N-[3-(2H-tetrazol-5-yl)phenyl]-N-(thiophen-2-ylmethyl)pentanamide Show/Hide	C17H19N5OS	1
1	Ki = 620 nM Bioactivity Info	TI LI LO TS
CP0515588 Compound Info	2-[1-[(2,5-dichlorophenyl)methyl]-3,5-diethylpyrazol-4-yl]acetic acid Show/Hide	C16H18Cl2N2O2	1
1	Ki = 623 nM Bioactivity Info	TI LI LO TS
CP0540767 Compound Info	2-[1-[(2-chlorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H15ClN2O2	1
1	Ki = 624 nM Bioactivity Info	TI LI LO TS
CP0416365 Compound Info	2-[3,5-diethyl-4-(naphthalen-2-ylmethyl)pyrazol-1-yl]acetic acid Show/Hide	C20H22N2O2	1
1	Ki = 631 nM Bioactivity Info	TI LI LO TS
CP0485751 Compound Info	2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,5'-dione}acetic acid Show/Hide	C20H17ClN2O4	1
1	Ki = 702 nM Bioactivity Info	TI LI LO TS
CP0478160 Compound Info	2-{1'-benzyl-5-fluoro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H15FN2O5	1
1	Ki = 712 nM Bioactivity Info	TI LI LO TS
CP0090560 Compound Info	2-[5-bromo-2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H17BrN2O4S	1
1	Ki = 735 nM Bioactivity Info	TI LI LO TS
CP0403126 Compound Info	2-{5-chloro-1'-[(2E)-3-phenylprop-2-en-1-yl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C22H17ClN2O5	1
1	Ki = 747 nM Bioactivity Info	TI LI LO TS
CP0456494 Compound Info	2-[2-[2-(2-chlorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H11ClO3	1
1	Ki = 747 nM Bioactivity Info	TI LI LO TS
CP0424661 Compound Info	2-[1-(1,3-benzothiazol-2-ylmethyl)-5'-chloro-3-methyl-2,2',5-trioxospiro[imidazolidine-4,3'-indole]-1'-yl]acetic acid Show/Hide	C21H15ClN4O5S	1
1	Ki = 750 nM Bioactivity Info	TI LI LO TS
CP0525265 Compound Info	2-[5-(2-phenyl-1,3-thiazole-4-carbonyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridin-1-yl]acetic acid Show/Hide	C18H16N4O3S	1
1	Ki = 752 nM Bioactivity Info	TI LI LO TS
CP0435028 Compound Info	4-[5-chloro-1'-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]butanoic acid Show/Hide	C18H17ClN2O5	1
1	Ki = 769 nM Bioactivity Info	TI LI LO TS
CP0321150 Compound Info	2-(2-cyclohexyl-4-methoxyphenoxy)acetic acid Show/Hide	C15H20O4	1
1	Ki = 782 nM Bioactivity Info	TI LI LO TS
CP0371641 Compound Info	3-(4-chloro-2-cyclohexylphenoxy)propanoic acid Show/Hide	C15H19ClO3	1
1	Ki = 799 nM Bioactivity Info	TI LI LO TS
CP0434995 Compound Info	2-[(3S)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H14Cl2N2O5	1
1	Ki = 870 nM Bioactivity Info	TI LI LO TS
CP0500618 Compound Info	2-[(3S)-5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H14ClFN2O5	1
1	Ki = 926 nM Bioactivity Info	TI LI LO TS
CP0517469 Compound Info	N-[(2-fluorophenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C17H16FN5O	1
1	Ki = 950 nM Bioactivity Info	TI LI LO TS
CP0436483 Compound Info	4-{5-chloro-1'-[(4-methoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}butanoic acid Show/Hide	C23H21ClN2O6	1
1	Ki = 960 nM Bioactivity Info	TI LI LO TS
CP0500996 Compound Info	2-[2-methyl-1-(pyridin-3-ylmethyl)pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C16H15N3O2	1
1	Ki = 1060 nM Bioactivity Info	TI LI LO TS
CP0388114 Compound Info	2-[4-chloro-2-(2-pyridin-2-ylethynyl)phenoxy]acetic acid Show/Hide	C15H10ClNO3	1
1	Ki = 1120 nM Bioactivity Info	TI LI LO TS
CP0506217 Compound Info	2-(1-(4-chloro-3-(trifluoromethyl)phenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H12ClF3N2O4S	1
1	Ki = 1171 nM Bioactivity Info	TI LI LO TS
CP0536780 Compound Info	2-[(3S)-5-chloro-1'-[(3-methoxyphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C21H17ClN2O6	1
1	Ki = 1172 nM Bioactivity Info	TI LI LO TS
CP0432883 Compound Info	N-[(4-fluorophenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C17H16FN5O	1
1	Ki = 1200 nM Bioactivity Info	TI LI LO TS
CP0422075 Compound Info	2-{5-chloro-1'-[(1-methyl-1H-1,2,3-benzotriazol-5-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C21H16ClN5O5	1
1	Ki = 1300 nM Bioactivity Info	TI LI LO TS
CP0242029 Compound Info	2-[2,5-dimethyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H20N2O4S	1
1	Ki = 1335 nM Bioactivity Info	TI LI LO TS
CP0427738 Compound Info	2-{1'-[(5-tert-butyl-1,2,4-oxadiazol-3-yl)methyl]-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C20H19ClN4O6	1
1	Ki = 1338 nM Bioactivity Info	TI LI LO TS
CP0432882 Compound Info	N-[(3-fluorophenyl)methyl]-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C17H16FN5O	1
1	Ki = 1400 nM Bioactivity Info	TI LI LO TS
CP0436485 Compound Info	2-[5-chloro-1'-(2-methoxyethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C16H15ClN2O6	1
1	Ki = 1448 nM Bioactivity Info	TI LI LO TS
CP0505966 Compound Info	2-[4-chloro-2-[2-(1-methylimidazol-2-yl)ethynyl]phenoxy]acetic acid Show/Hide	C14H11ClN2O3	1
1	Ki = 1470 nM Bioactivity Info	TI LI LO TS
CP0435021 Compound Info	2-{5-chloro-1'-[(4-methanesulfonylphenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C21H17ClN2O7S	1
1	Ki = 1506 nM Bioactivity Info	TI LI LO TS
CP0536835 Compound Info	1'-benzyl-5-chloro-1-(1H-1,2,3,4-tetrazol-5-ylmethyl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione Show/Hide	C20H15ClN6O3	1
1	Ki = 1536 nM Bioactivity Info	TI LI LO TS
CP0536836 Compound Info	4-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}butanoic acid Show/Hide	C22H19ClN2O5	1
1	Ki = 1660 nM Bioactivity Info	TI LI LO TS
CP0435910 Compound Info	N-benzyl-N-[3-(2H-tetrazol-5-yl)phenyl]propanamide Show/Hide	C17H17N5O	1
1	Ki = 1800 nM Bioactivity Info	TI LI LO TS
CP0288742 Compound Info	4-(4-chloro-2-cyclohexylphenoxy)butanoic acid Show/Hide	C16H21ClO3	1
1	Ki = 1990 nM Bioactivity Info	TI LI LO TS
CP0536781 Compound Info	2-[(3S)-1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid Show/Hide	C20H15ClN2O5	1
1	Ki = 2044 nM Bioactivity Info	TI LI LO TS
CP0513854 Compound Info	2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2'-dione}acetic acid Show/Hide	C24H20ClN3O5	2
1	Ki = 2200 nM Bioactivity Info	TI LI LO TS
2	Ki = 2237 nM Bioactivity Info	TI LI LO TS
CP0490097 Compound Info	2-[2-methyl-1-(pyridin-4-ylmethyl)pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C16H15N3O2	1
1	Ki = 2230 nM Bioactivity Info	TI LI LO TS
CP0216457 Compound Info	(R)-2-(4-chloro-2-cyclohexylphenoxy)propanoic acid Show/Hide	C15H19ClO3	1
1	Ki = 2250 nM Bioactivity Info	TI LI LO TS
CP0439275 Compound Info	2-(1-(4-methoxyphenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C17H16N2O5S	1
1	Ki = 2619 nM Bioactivity Info	TI LI LO TS
CP0516327 Compound Info	2-{1'-benzyl-5-methoxy-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C21H18N2O6	1
1	Ki = 2741 nM Bioactivity Info	TI LI LO TS
CP0490096 Compound Info	2-[2-methyl-1-(pyridin-2-ylmethyl)pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C16H15N3O2	1
1	Ki = 2940 nM Bioactivity Info	TI LI LO TS
CP0497382 Compound Info	2-(1-(2-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H13ClN2O4S	1
1	Ki = 3220 nM Bioactivity Info	TI LI LO TS
CP0194852 Compound Info	methyl 2-(4-chloro-2-cyclohexylphenoxy)acetate Show/Hide	C15H19ClO3	1
1	Ki = 3280 nM Bioactivity Info	TI LI LO TS
CP0000254 Compound Info	(Z)-2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid Show/Hide	C20H17FO2S	1
1	Ki = 3500 nM Bioactivity Info	TI LI LO TS
CP0394202 Compound Info	2-{5-fluoro-1'-[(2-methoxyethoxy)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C17H17FN2O7	1
1	Ki = 3829 nM Bioactivity Info	TI LI LO TS
CP0478156 Compound Info	4-[5-fluoro-1'-(prop-2-en-1-yl)-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]butanoic acid Show/Hide	C18H17FN2O5	1
1	Ki = 4131 nM Bioactivity Info	TI LI LO TS
CP0407993 Compound Info	4-{1'-benzyl-5-fluoro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}butanoic acid Show/Hide	C22H19FN2O5	1
1	Ki = 4174 nM Bioactivity Info	TI LI LO TS
CP0435992 Compound Info	2-[3-[2,3-dihydro-1,4-benzodioxin-6-ylmethyl(pentanoyl)amino]phenyl]acetic acid Show/Hide	C22H25NO5	1
1	Ki = 4300 nM Bioactivity Info	TI LI LO TS
CP0373103 Compound Info	2-{5-chloro-1'-[(dimethylcarbamoyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C17H16ClN3O6	1
1	Ki = 4669 nM Bioactivity Info	TI LI LO TS
CP0459325 Compound Info	2-[2-[2-(2-chlorophenyl)ethynyl]-5-fluorophenoxy]acetic acid Show/Hide	C16H10ClFO3	1
1	Ki = 4780 nM Bioactivity Info	TI LI LO TS
CP0136016 Compound Info	2-(2-allyl-4-chlorophenoxy)acetic acid Show/Hide	C11H11ClO3	1
1	Ki = 5130 nM Bioactivity Info	TI LI LO TS
CP0435026 Compound Info	2-{5-chloro-1'-methyl-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C14H11ClN2O5	1
1	Ki = 7615 nM Bioactivity Info	TI LI LO TS
CP0432886 Compound Info	3-[(3-methoxyphenyl)methyl-pentanoylamino]benzoic acid Show/Hide	C20H23NO4	1
1	Ki = 8000 nM Bioactivity Info	TI LI LO TS
CP0373100 Compound Info	4-{5-fluoro-1'-methyl-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}butanoic acid Show/Hide	C16H15FN2O5	1
1	Ki = 8903 nM Bioactivity Info	TI LI LO TS
CP0094725 Compound Info	((4-chloro-o-tolyl)oxy)acetic acid, Show/Hide	C9H9ClO3	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0221441 Compound Info	2-(4-chloro-2-cyclohexylphenoxy)-N-(methylsulfonyl)acetamide Show/Hide	C15H20ClNO4S	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0307487 Compound Info	2-(4-chloro-2-cyclohexylphenoxy)ethanol Show/Hide	C14H19ClO2	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0315425 Compound Info	5-((4-chloro-2-cyclohexylphenoxy)methyl)-1H-tetrazole Show/Hide	C14H17ClN4O	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0407997 Compound Info	1'-benzyl-5-chloro-1-methyl-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione Show/Hide	C19H15ClN2O3	1
1	Ki = 11629 nM Bioactivity Info	TI LI LO TS
CP0435030 Compound Info	Spiro-indolinone analogue, 51 Show/Hide	C22H19ClN2O5	1
1	Ki > 30000 nM Bioactivity Info	TI LI LO TS
CP0529891 Compound Info	2-{1'-[(dimethylcarbamoyl)methyl]-5-fluoro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid Show/Hide	C17H16FN3O6	1
1	Ki > 30000 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000108 , CCRF-CEM

Cell Line Info

Cell Line ID: CL001011 , CHO-1

Cell Line Info

Cell Line ID: CL000026 , CHO-K1

Cell Line Info

Cell Line ID: CL000076 , CHO/Galpha16

Cell Line Info

Cell Line ID: CL000053 , COS-7

Cell Line Info

Cell Line ID: CL000025 , HEK-293T

Cell Line Info

Cell Line ID: CL000006 , HEK293

Cell Line Info

Cell Line ID: CL000065 , HEK293-EBNA

Cell Line Info

Cell Line ID: CL000771 , HEK385-7

Cell Line Info

Cell Line ID: CL000465 , KB-ChR-8-5

Cell Line Info

Cell Line ID: CL000783 , UE6E7T-2

Cell Line Info

Cell Line ID: CL000602 , ValiScreen human CRTH2

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0081955 Compound Info	Fevipiprant Show/Hide	C19H17F3N2O4S	1
1	IC50 = 0.4 nM
CP0086262 Compound Info	4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)(phenyl)amino)-4-oxobutanoic acid Show/Hide	C27H26N2O4	2
1	IC50 = 0.77 nM
2	IC50 = 3 nM
CP0057623 Compound Info	2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid Show/Hide	C23H18F3N3O3	2
1	IC50 = 0.8 nM
2	IC50 = 1.2 nM
CP0445485 Compound Info	2-[1-[[4-ethylsulfonyl-2-(trifluoromethyl)phenyl]methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C20H19F3N2O4S	2
1	IC50 = 0.8 nM
2	IC50 = 4 nM
CP0164558 Compound Info	2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl)biphenyl-2-yloxy)acetic acid Show/Hide	C18H17F3O5S	1
1	IC50 = 0.9 nM
CP0190339 Compound Info	2-[1-[2-[(3,5-dimethyl-1,2,4-triazol-4-yl)methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C22H23N5O2	1
1	IC50 = 1 nM
CP0205017 Compound Info	2-[1-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C24H22FN3O3	1
1	IC50 = 1 nM
CP0124983 Compound Info	2-[5-fluoro-2-methyl-3-(1-oxo-2-propan-2-ylisoquinolin-4-yl)indol-1-yl]acetic acid Show/Hide	C23H21FN2O3	3
1	IC50 = 1.2 nM
2	IC50 = 1.4 nM
3	IC50 = 8 nM
CP0090559 Compound Info	2-[1-[(2-chloro-4-ethylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H19ClN2O4S	2
1	IC50 = 1.3 nM
2	IC50 = 7 nM
CP0268086 Compound Info	2-[8-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]acetic acid Show/Hide	C23H22F3N3O3	1
1	IC50 = 1.4 nM
CP0290305 Compound Info	2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid Show/Hide	C15H10ClNO3	1
1	IC50 = 1.7 nM
CP0081954 Compound Info	2-[1-[(2-chloro-4-methylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H17ClN2O4S	2
1	IC50 = 1.7 nM
2	IC50 = 47 nM
CP0152548 Compound Info	2-[3-[2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindol-1-yl]acetic acid Show/Hide	C24H20F4N4O2	1
1	IC50 = 2 nM
CP0559112 Compound Info	2-[1-[2-[(3-benzyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-chlorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C27H24ClN5O2	1
1	IC50 = 2 nM
CP0032668 Compound Info	(R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid Show/Hide	C21H21FN2O4S	5
1	IC50 = 2.2 nM
2	IC50 = 6 nM
3	IC50 = 20 nM
4	Ki = 2.5 nM
5	Ki ~ 2.5 nM
CP0054111 Compound Info	2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H18N2O4S	6
1	IC50 = 3 nM
2	IC50 = 4 nM
3	IC50 = 5 nM
4	IC50 = 31 nM
5	IC50 = 102 nM
6	IC50 > 10000 nM
CP0244713 Compound Info	2-[5-fluoro-2-methyl-3-[1-oxo-2-(4,4,4-trifluorobutyl)isoquinolin-4-yl]indol-1-yl]acetic acid Show/Hide	C24H20F4N2O3	1
1	IC50 = 3 nM
CP0078264 Compound Info	2-[3-[2-[[ethyl-[(4-fluorophenyl)methoxycarbonyl]amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H25F4NO5	1
1	IC50 = 4 nM
CP0057143 Compound Info	2-[4-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid Show/Hide	C25H21FN2O4S	2
1	IC50 = 4 nM
2	IC50 = 50 nM
CP0251229 Compound Info	2-[1-[2-[[2-(cyclopropylmethyl)-4-methylpyrazol-3-yl]methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C26H28N4O2	1
1	IC50 = 4 nM
CP0533194 Compound Info	2-[1-[4-chloro-2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C23H22ClN5O2	1
1	IC50 = 4 nM
CP0246918 Compound Info	2-[2-methyl-1-[(2-methyl-4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H20N2O4S	2
1	IC50 = 4 nM
2	IC50 = 32 nM
CP0248457 Compound Info	2-[2-methyl-1-[[4-methylsulfonyl-3-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H17F3N2O4S	2
1	IC50 = 4 nM
2	IC50 = 11 nM
CP0248458 Compound Info	2-[1-[(4-ethylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H20N2O4S	1
1	IC50 = 4 nM
CP0236140 Compound Info	2-[4-acetamido-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid Show/Hide	C19H17ClN2O3S	1
1	IC50 = 4.3 nM
CP0379513 Compound Info	2-[1-[2-[[benzylcarbamoyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C28H27F3N4O3	1
1	IC50 = 4.7 nM
CP0284998 Compound Info	2-[3-[2-[[ethyl(phenylmethoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H26F3NO5	1
1	IC50 = 5 nM
CP0332239 Compound Info	2-[3-[2-[[(3,5-difluorophenyl)methoxycarbonyl-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H24F5NO5	1
1	IC50 = 5 nM
CP0153758 Compound Info	2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid Show/Hide	C24H20FNO4S	1
1	IC50 = 5 nM
CP0213000 Compound Info	2-[1-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C25H22F3N3O3	1
1	IC50 = 5 nM
CP0379947 Compound Info	2-[1-[4-chloro-2-[[3-methyl-5-(2-phenylethyl)-1,2,4-triazol-4-yl]methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C28H26ClN5O2	1
1	IC50 = 5 nM
CP0352580 Compound Info	2-[1-[2-[[ethyl-(2-methoxyacetyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C23H24F3N3O4	1
1	IC50 = 5 nM
CP0057091 Compound Info	2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid Show/Hide	C21H17FN2O2	3
1	IC50 = 6 nM
2	IC50 = 44 nM
3	IC50 = 100 nM
CP0074938 Compound Info	2-[3-[2-[[(4-chlorophenyl)methoxycarbonyl-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H25ClF3NO5	1
1	IC50 = 6 nM
CP0152546 Compound Info	2-[1-[2-[(2,4-dimethylpyrazol-3-yl)methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C22H21FN4O2	1
1	IC50 = 6 nM
CP0192069 Compound Info	2-[7-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-6-methylpyrrolo[1,2-c]pyrimidin-5-yl]acetic acid Show/Hide	C24H21FN2O5S	1
1	IC50 = 6 nM
CP0106923 Compound Info	2-[6-ethyl-2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C20H22N2O4S	1
1	IC50 = 6 nM
CP0053336 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C23H24FN3O3	1
1	IC50 = 6.4 nM
CP0114154 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C23H24F3NO4	3
1	IC50 = 6.5 nM
2	IC50 = 13 nM
3	Ki = 13.5 nM
CP0067960 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethoxy)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C24H24F3N3O4	1
1	IC50 = 6.7 nM
CP0073144 Compound Info	5-[7-[(5S)-5-(1,3-benzoxazol-2-yl)-5-methyl-4H-1,2-oxazol-3-yl]-3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]pentanoic acid Show/Hide	C30H25FN4O5	1
1	IC50 = 6.8 nM
CP0274739 Compound Info	2-[3-[2-[[(3-chlorophenyl)methoxycarbonyl-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H25ClF3NO5	1
1	IC50 = 7 nM
CP0275045 Compound Info	2-[3-[2-[[(2-chlorophenyl)methoxycarbonyl-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H25ClF3NO5	1
1	IC50 = 7 nM
CP0248255 Compound Info	2-[1-[2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-6-fluoroindol-3-yl]acetic acid Show/Hide	C24H20F4N4O2	1
1	IC50 = 7 nM
CP0248107 Compound Info	2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-b]pyridazin-5-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 7.3 nM
CP0428206 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]-6-(trifluoromethyl)indol-3-yl]acetic acid Show/Hide	C24H23F3N2O3	1
1	IC50 = 7.7 nM
CP0393995 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 7.8 nM
CP0168575 Compound Info	2-[3-[2-[[ethyl(methoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C21H22F3NO5	1
1	IC50 = 8 nM
CP0211747 Compound Info	2-[5-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methyl]indol-1-yl]acetic acid Show/Hide	C19H18FNO4S	2
1	IC50 = 8 nM
2	Ki = 7 nM
CP0268081 Compound Info	2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid Show/Hide	C23H22N2O5S	1
1	IC50 = 8 nM
CP0248102 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-(difluoromethyl)pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C24H22F5N3O3	1
1	IC50 = 8 nM
CP0146156 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[3,2-c]pyridin-1-yl]acetic acid Show/Hide	C23H22F3N3O3	1
1	IC50 = 8 nM
CP0418290 Compound Info	2-[1-[2-[[cyclobutanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C25H26F3N3O3	1
1	IC50 = 8.5 nM
CP0075039 Compound Info	2-[4-methoxy-3-[2-[[methyl(phenylmethoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]phenyl]acetic acid Show/Hide	C26H24F3NO5	1
1	IC50 = 9 nM
CP0245256 Compound Info	2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H12F2N2O4S	1
1	IC50 = 9 nM
CP0248105 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C23H25N3O3	1
1	IC50 = 9.5 nM
CP0168572 Compound Info	2-[3-[2-[[cyclopropyl(phenylmethoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C28H26F3NO5	1
1	IC50 = 10 nM
CP0042075 Compound Info	2-[3-[(E)-2-cyano-3-(3,4-dihydro-2H-quinolin-1-yl)-3-oxoprop-1-enyl]indol-1-yl]acetic acid Show/Hide	C23H19N3O3	3
1	IC50 = 10 nM
2	IC50 = 14 nM
3	IC50 = 160 nM
CP0054194 Compound Info	2-[1-[4-chloro-2-[(3,5-dicyclopropyl-1,2-oxazol-4-yl)methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C26H24ClN3O3	1
1	IC50 = 10 nM
CP0326124 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-methylpyrrolo[3,2-b]pyridin-1-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 10 nM
CP0248104 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C22H22FN3O3	1
1	IC50 = 11 nM
CP0379325 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]indol-1-yl]acetic acid Show/Hide	C23H23FN2O3	1
1	IC50 = 11 nM
CP0192068 Compound Info	2-[7-[[2-(benzenesulfonyl)phenyl]methyl]-6-methylpyrrolo[1,2-c]pyrimidin-5-yl]acetic acid Show/Hide	C23H20N2O4S	1
1	IC50 = 12 nM
CP0331846 Compound Info	2-[5-chloro-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid Show/Hide	C17H13Cl2NO2S	1
1	IC50 = 13 nM
CP0532208 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C24H27N3O3	1
1	IC50 = 13 nM
CP0555198 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-methylindazol-1-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 13 nM
CP0155783 Compound Info	2-[3-[2-[[cyclobutyl(phenylmethoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C29H28F3NO5	1
1	IC50 = 14 nM
CP0155787 Compound Info	2-[3-[2-[[(3,5-dichlorophenyl)methoxycarbonyl-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C27H24Cl2F3NO5	1
1	IC50 = 14 nM
CP0326123 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[3,2-b]pyridin-1-yl]acetic acid Show/Hide	C23H22F3N3O3	2
1	IC50 = 14 nM
2	IC50 = 15 nM
CP0147599 Compound Info	2-[1-[[2,4-bis(trifluoromethyl)phenyl]methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C19H14F6N2O2	2
1	IC50 = 14 nM
2	IC50 = 214 nM
CP0275058 Compound Info	2-[3-(4-chlorophenyl)sulfanyl-2,5-dimethylindol-1-yl]acetic acid Show/Hide	C18H16ClNO2S	1
1	IC50 = 15 nM
CP0070143 Compound Info	2-(2-benzoyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid Show/Hide	C20H18N2O3	3
1	IC50 = 15 nM
2	IC50 = 17 nM
3	IC50 = 110 nM
CP0190341 Compound Info	2-[3-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-fluorophenyl]-5-(trifluoromethyl)indol-1-yl]acetic acid Show/Hide	C25H20F4N2O3	1
1	IC50 = 16 nM
CP0271723 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]-5-(trifluoromethyl)indol-1-yl]acetic acid Show/Hide	C24H22F4N2O3	1
1	IC50 = 17 nM
CP0260457 Compound Info	2-[3-[2-(2,2-dimethylpropyl)-1-oxoisoquinolin-4-yl]-5-fluoro-2-methylindol-1-yl]acetic acid Show/Hide	C25H25FN2O3	1
1	IC50 = 18 nM
CP0248101 Compound Info	2-[5-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-fluoroindazol-1-yl]acetic acid Show/Hide	C23H20ClF4N3O3	1
1	IC50 = 18 nM
CP0248106 Compound Info	2-[1-[4-chloro-2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C23H24ClN3O3	1
1	IC50 = 18 nM
CP0124982 Compound Info	2-[5-fluoro-2-methyl-3-[1-oxo-2-(2,2,2-trifluoroethyl)isoquinolin-4-yl]indol-1-yl]acetic acid Show/Hide	C22H16F4N2O3	1
1	IC50 = 19 nM
CP0326952 Compound Info	2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[1,2-c]pyrimidin-5-yl]acetic acid Show/Hide	C23H22F3N3O3	1
1	IC50 = 19 nM
CP0071202 Compound Info	2-(2,5-dimethyl-3-phenylsulfanylindol-1-yl)acetic acid Show/Hide	C18H17NO2S	1
1	IC50 = 20 nM
CP0052912 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C23H22F3N3O3	2
1	IC50 = 20 nM
2	IC50 = 34 nM
CP0323455 Compound Info	2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]indol-3-yl]acetic acid Show/Hide	C19H19NO4S	2
1	IC50 = 20 nM
2	IC50 = 188 nM
CP0155789 Compound Info	2-[3-[2-[[benzyl(methoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C26H24F3NO5	1
1	IC50 = 22 nM
CP0490050 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(cyclopropylmethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C26H26F3N3O3	1
1	IC50 = 22 nM
CP0209430 Compound Info	2-[1-[(4-chlorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H15ClN2O2	1
1	IC50 = 23 nM
CP0146214 Compound Info	2-[5-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid Show/Hide	C23H21ClF3N3O3	1
1	IC50 = 23 nM
CP0268091 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-fluoroindazol-1-yl]acetic acid Show/Hide	C23H21F4N3O3	1
1	IC50 = 23 nM
CP0379870 Compound Info	2-[2-methyl-1-[(4-nitrophenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C17H15N3O4	1
1	IC50 = 24 nM
CP0146136 Compound Info	2-[8-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-a]pyrimidin-6-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 24 nM
CP0067963 Compound Info	2-[1-[2-[[ethyl-(2-phenylacetyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C28H26F3N3O3	1
1	IC50 = 25 nM
CP0463113 Compound Info	2-[8-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-a]pyrimidin-6-yl]acetic acid Show/Hide	C25H22F3N3O3	1
1	IC50 = 26 nM
CP0263118 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyindazol-1-yl]acetic acid Show/Hide	C24H24F3N3O4	1
1	IC50 = 27 nM
CP0318457 Compound Info	2-[1-[2-[[(2-cyclopropylacetyl)-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C25H26F3N3O3	1
1	IC50 = 29 nM
CP0274713 Compound Info	2-[4-methoxy-3-[2-[[methoxycarbonyl(2-phenylethyl)amino]methyl]-4-(trifluoromethyl)phenyl]phenyl]acetic acid Show/Hide	C27H26F3NO5	1
1	IC50 = 34 nM
CP0055874 Compound Info	2-[8-fluoro-2-(thiophene-2-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C18H15FN2O3S	1
1	IC50 = 34 nM
CP0089062 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindazol-1-yl]acetic acid Show/Hide	C23H21F4N3O3	1
1	IC50 = 34 nM
CP0326950 Compound Info	2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-2-methylindazol-5-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 43 nM
CP0089061 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid Show/Hide	C23H22F3N3O3	1
1	IC50 = 47 nM
CP0055420 Compound Info	2-[2-(3-chlorobenzoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C20H17ClN2O3	1
1	IC50 = 50 nM
CP0055873 Compound Info	2-[8-fluoro-2-[2-(1H-indol-3-yl)acetyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C23H20FN3O3	1
1	IC50 = 50 nM
CP0057144 Compound Info	2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid Show/Hide	C25H22N2O4S	2
1	IC50 = 50 nM
2	IC50 = 240 nM
CP0054115 Compound Info	2-[2-methyl-1-[(4-methylsulfinylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H18N2O3S	1
1	IC50 = 51 nM
CP0168573 Compound Info	2-[3-[2-[[cyclopentyl(phenylmethoxycarbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid Show/Hide	C30H30F3NO5	1
1	IC50 = 53 nM
CP0559113 Compound Info	2-[3-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyrrolo[3,2-b]pyridin-1-yl]acetic acid Show/Hide	C25H19F6N3O3	1
1	IC50 = 54 nM
CP0313886 Compound Info	2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-1-methylindazol-5-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 58 nM
CP0045673 Compound Info	2-[2-(3-chlorobenzoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C20H16ClFN2O3	1
1	IC50 = 60 nM
CP0248258 Compound Info	2-[1-[2-[(3,5-dicyclopropyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C27H24F3N3O3	1
1	IC50 = 60 nM
CP0248109 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(2-phenoxyethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C30H28F3N3O4	1
1	IC50 = 60 nM
CP0248267 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indol-1-yl]acetic acid Show/Hide	C24H23F3N2O3	1
1	IC50 = 63 nM
CP0248944 Compound Info	2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-pyridin-4-ylpyrazol-4-yl]acetic acid Show/Hide	C24H21N3O4S	1
1	IC50 = 66 nM
CP0146132 Compound Info	2-[4-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindazol-1-yl]acetic acid Show/Hide	C23H20ClF4N3O3	1
1	IC50 = 71 nM
CP0406725 Compound Info	2-[4-chloro-2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid Show/Hide	C18H17ClN2O4S	1
1	IC50 = 80 nM
CP0052915 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyrrolo[3,2-b]pyridin-1-yl]acetic acid Show/Hide	C24H21F6N3O3	1
1	IC50 = 82 nM
CP0271724 Compound Info	2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indol-3-yl]acetic acid Show/Hide	C24H23F3N2O3	1
1	IC50 = 84 nM
CP0146154 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]imidazo[1,5-a]pyridin-1-yl]acetic acid Show/Hide	C23H22F3N3O3	1
1	IC50 = 94 nM
CP0042410 Compound Info	2-[8-chloro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C24H19ClN2O3	1
1	IC50 = 100 nM
CP0379512 Compound Info	2-[4-cyano-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid Show/Hide	C24H21F3N4O3	1
1	IC50 = 103 nM
CP0259564 Compound Info	2-[5-fluoro-2-methyl-1-(4-methylsulfonylphenyl)sulfonylindol-3-yl]acetic acid Show/Hide	C18H16FNO6S2	1
1	IC50 = 106 nM
CP0054110 Compound Info	2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid Show/Hide	C16H13ClN2O4S	1
1	IC50 = 108 nM
CP0146213 Compound Info	2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methylindazol-1-yl]acetic acid Show/Hide	C24H24F3N3O3	1
1	IC50 = 108 nM
CP0266551 Compound Info	2-[4-chloro-2-[2-(2-chlorophenyl)ethynyl]phenoxy]acetic acid Show/Hide	C16H10Cl2O3	1
1	IC50 = 123 nM
CP0055877 Compound Info	2-[2-benzoyl-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C21H17F3N2O3	1
1	IC50 = 130 nM
CP0129137 Compound Info	2-[4-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid Show/Hide	C23H21ClF3N3O3	1
1	IC50 = 160 nM
CP0261961 Compound Info	2-[2-(naphthalene-1-carbonyl)-8-(trifluoromethyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C25H19F3N2O3	1
1	IC50 = 180 nM
CP0083568 Compound Info	2-[8-fluoro-2-(3-naphthalen-1-ylpropanoyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C26H23FN2O3	1
1	IC50 = 210 nM
CP0087804 Compound Info	ACT-129968 Show/Hide	C24H19FN2O3	1
1	IC50 = 235 nM
CP0042409 Compound Info	2-[2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C28H26N2O3	1
1	IC50 = 240 nM
CP0337477 Compound Info	2-(5-nitrobiphenyl-2-yloxy)acetic acid Show/Hide	C14H11NO5	1
1	IC50 = 251 nM
CP0086409 Compound Info	2-[8-fluoro-2-(2-naphthalen-1-ylacetyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C25H21FN2O3	1
1	IC50 = 275 nM
CP0048953 Compound Info	(R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid Show/Hide	C21H21FN2O4S	2
1	IC50 = 311 nM
2	IC50 = 754 nM
CP0227496 Compound Info	2-(5-bromobiphenyl-2-yloxy)acetic acid Show/Hide	C14H11BrO3	1
1	IC50 = 316 nM
CP0130562 Compound Info	2-[8-methyl-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C25H22N2O3	1
1	IC50 = 340 nM
CP0290306 Compound Info	2-(5-cyanobiphenyl-2-yloxy)acetic acid Show/Hide	C15H11NO3	1
1	IC50 = 355 nM
CP0368551 Compound Info	2-[3-[(E)-3-(3-bromoanilino)-2-cyano-3-oxoprop-1-enyl]indol-1-yl]acetic acid Show/Hide	C20H14BrN3O3	1
1	IC50 = 500 nM
CP0074661 Compound Info	2-[4-methoxy-3-[2-(phenylmethoxycarbonylaminomethyl)-4-(trifluoromethyl)phenyl]phenyl]acetic acid Show/Hide	C25H22F3NO5	1
1	IC50 = 709 nM
CP0534082 Compound Info	2-(5-methylbiphenyl-2-yloxy)acetic acid Show/Hide	C15H14O3	1
1	IC50 = 794 nM
CP0102785 Compound Info	2-[2-[[2-(benzenesulfonyl)phenyl]methyl]-3-methyl-5-oxo-1H-pyrazol-4-yl]acetic acid Show/Hide	C19H18N2O5S	1
1	IC50 = 1000 nM
CP0055416 Compound Info	2-[2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid Show/Hide	C24H20N2O3	1
1	IC50 = 1120 nM
CP0086384 Compound Info	2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-3,5-dimethylpyrazol-4-yl]acetic acid Show/Hide	C20H20N2O4S	1
1	IC50 = 1700 nM
CP0287604 Compound Info	2-(5-(thiazol-2-yl)biphenyl-2-yloxy)acetic acid Show/Hide	C17H13NO3S	1
1	IC50 = 1778 nM
CP0363009 Compound Info	2-[3,5-dimethyl-1-[3-[[(1S,2S)-2-phenylcyclopropanecarbonyl]amino]phenyl]pyrazol-4-yl]acetic acid Show/Hide	C23H23N3O3	1
1	IC50 = 2100 nM
CP0042334 Compound Info	2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid Show/Hide	C25H22N2O4S	1
1	IC50 = 2400 nM
CP0248945 Compound Info	2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-3-(4-chlorophenyl)-5-methylpyrazol-4-yl]acetic acid Show/Hide	C25H21ClN2O4S	1
1	IC50 = 8100 nM
CP0073515 Compound Info	(R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[2,3-b]indolizin-10-yl)acetic acid Show/Hide	C20H20FN3O4S	2
1	IC50 = 24900 nM
2	IC50 = 51000 nM
CP0227731 Compound Info	2-[3-cyclopropyl-5-ethyl-1-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]pyrazol-4-yl]acetic acid Show/Hide	C25H24F3N3O3	1
1	Ki = 0.5 nM
CP0301754 Compound Info	2-[1-[[4-[[4-chloro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]-3,5-diethylpyrazol-4-yl]acetic acid Show/Hide	C24H24ClF3N2O3	1
1	Ki = 4.8 nM
CP0032219 Compound Info	(R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-2-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid Show/Hide	C22H23FN2O6S2	2
1	Ki = 1083 nM
2	Ki ~ 1083 nM

Clinical Information about the Protein

Target 1 ( Prostaglandin D2 receptor 2 (PTGDR2) )

Target Type	Clinical trial Target
Disease	9 Target-related Diseases				9
1	Asthma [ICD-11: CA23]
2	Perennial allergic rhinitis [ICD-11: CA08.03]
3	Allergic asthma [ICD-11: CA23.0]
4	Chronic obstructive pulmonary disease [ICD-11: CA22]
5	Allergy [ICD-11: 4A80-4A85]
6	Allergic rhinitis [ICD-11: CA08.0]
7	Respiratory disease [ICD-11: CB40]
8	Solid tumour/cancer [ICD-11: 2A00-2F9Z]
9	Coronary heart disease [ICD-11: BA80.Z]
Approved Drug(s)	1 Approved Drug				1
1	LAROPIPRANT	Drug Info	Phase 4	Coronary heart disease
Clinical Trial Drug(s)	12 Clinical Trial Drugs				12
1	Fevipiprant	Drug Info	Phase 3	Asthma
2	Setipiprant	Drug Info	Phase 3	Asthma
3	Ramatroban	Drug Info	Phase 2/3	Perennial allergic rhinitis
4	AMG 853	Drug Info	Phase 2	Asthma
5	ARRY-502	Drug Info	Phase 2	Allergic asthma
6	AZD1981	Drug Info	Phase 2	Chronic obstructive pulmonary disease
7	OC-000459	Drug Info	Phase 2	Allergy
8	QAV-680	Drug Info	Phase 2	Allergic rhinitis
9	AM-211	Drug Info	Phase 1	Asthma
10	AP-761	Drug Info	Phase 2	Asthma
11	MK-7246	Drug Info	Phase 1	Respiratory disease
12	PGF2alpha	Drug Info	Clinical trial	Solid tumour/cancer
Investigative Drug(s)	1 Investigative Drug				1
1	CAY 10471	Drug Info	Investigative	Allergy

Similar Protein(s) and Bioactivity Statistics

50% Identity

Protein ID	Protein Name	Protein Organism
PT04403	Prostaglandin D2 receptor 2	Mus musculus, Mouse	Protein Info

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han