Brief Information of the Compound and Protein
Compound Name
2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid
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PubChem ID
CID: 15950271
SID: 22421692
Canonical SMILES
OC(=O)CN1C(=O)C2(CC(=O)N(Cc3ccccc3)C2=O)c2cc(Cl)ccc12
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Compound Formula C20H15ClN2O5
Compound Structure
Protein Name
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 418 nM
   TI
   LI
   LO
   TS
2
Ki = 196 nM
   TI
   LI
   LO
   TS