Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000741
Cell Line Name	NRK-52E
Synonyms	NRK 52E NRK52E NRK clone 52E Normal Rat Kidney-52E NRK-E52
Category	Spontaneously immortalized cell line
Organism	Rattus norvegicus (Rat)
Cellosaurus ID	CVCL_0468
Tissue Information	Kidney
Disease	None

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT06297, Apelin receptor

Protein Info

Compound ID	Compound Name	Compound Formula
CP0962540 Compound Info	(2S)-5-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-2-(hexadecanoylamino)-5-oxo-pentanoic acid Show/Hide	C79H128N18O16S2	1
1	EC50 = 6.89 nM Bioactivity Info	TI LI LO TS
CP0965667 Compound Info	(2S)-2-[3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-5-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid Show/Hide	C78H127N19O22S2	1
1	EC50 = 7.84 nM Bioactivity Info	TI LI LO TS
CP0957394 Compound Info	(2S)-5-[[(5S)-5-amino-6-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-6-oxo-hexyl]amino]-2-(hexadecanoylamino)-5-oxo-pentanoic acid Show/Hide	C85H140N20O17S2	1
1	EC50 = 7.98 nM Bioactivity Info	TI LI LO TS
CP0962539 Compound Info	CMPLHSRVPFP-amide Show/Hide	C58H91N17O12S2	1
1	EC50 = 8.83 nM Bioactivity Info	TI LI LO TS
CP0965668 Compound Info	(2S)-5-[[(5S)-6-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-[[4-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-4-oxo-butanoyl]amino]-6-oxo-hexyl]amino]-2-(hexadecanoylamino)-5-oxo-pentanoic acid Show/Hide	C147H233N37O31S4	1
1	EC50 = 9.48 nM Bioactivity Info	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Kidney)

Cell Line Name		Organism	Disease
G-402	Cell Line Info	Homo sapiens (Human)	Kidney neoplasm
A-498	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
786-O	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
SN12C	Cell Line Info	Homo sapiens (Human)	Renal cell carcinoma
G-401	Cell Line Info	Homo sapiens (Human)	Rhabdoid tumor of the kidney
AU-BEK	Cell Line Info	Bos taurus (Bovine)	-
MDCK	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-II	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-I	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-MDR1	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCKII-LE	Cell Line Info	Canis lupus familiaris (Dog)	-
DK	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK2/BCRP	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-Net6	Cell Line Info	Canis lupus familiaris (Dog)	-
MDCK-UT-A1-AQP1-YFP	Cell Line Info	Canis lupus familiaris (Dog)	-
CV-1	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-7	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-1	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS-M6	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
COS	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
OAT1-COS7	Cell Line Info	Chlorocebus aethiops (Green monkey)	-
BS-C-1	Cell Line Info	Chlorocebus pygerythrus (Vervet monkey)	-
Vero	Cell Line Info	Chlorocebus sabaeus (Green monkey)	-
OK	Cell Line Info	Didelphis virginiana (North American opossum)	-
HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-293T	Cell Line Info	Homo sapiens (Human)	-
tsA201	Cell Line Info	Homo sapiens (Human)	-
HEK293-A	Cell Line Info	Homo sapiens (Human)	-
T-REx-293	Cell Line Info	Homo sapiens (Human)	-
HEK293-EBNA	Cell Line Info	Homo sapiens (Human)	-
Expi293F	Cell Line Info	Homo sapiens (Human)	-
Flp-In-293	Cell Line Info	Homo sapiens (Human)	-
HEK293S	Cell Line Info	Homo sapiens (Human)	-
HEK293-F	Cell Line Info	Homo sapiens (Human)	-
HEK293-EBNA1-6E	Cell Line Info	Homo sapiens (Human)	-
AD-293	Cell Line Info	Homo sapiens (Human)	-
HEK293-H	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hNOD2	Cell Line Info	Homo sapiens (Human)	-
HEK293T/17	Cell Line Info	Homo sapiens (Human)	-
293T/ACE2 [Japan 2021]	Cell Line Info	Homo sapiens (Human)	-
GripTite 293 MSR	Cell Line Info	Homo sapiens (Human)	-
HL-2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR8	Cell Line Info	Homo sapiens (Human)	-
PathHunter HEK 293 EDG1 Total GPCR Internalization	Cell Line Info	Homo sapiens (Human)	-
Flp-In-T-REx-293	Cell Line Info	Homo sapiens (Human)	-
HEKR2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue IL-6	Cell Line Info	Homo sapiens (Human)	-
HK-2 [Human kidney]	Cell Line Info	Homo sapiens (Human)	-
HEK293-FT	Cell Line Info	Homo sapiens (Human)	-
HEK-2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR2	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR4	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue CD40L	Cell Line Info	Homo sapiens (Human)	-
Expi293F GnTI-	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hNOD1	Cell Line Info	Homo sapiens (Human)	-
pEAK Rapid	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR9	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue hTLR7	Cell Line Info	Homo sapiens (Human)	-
293Ta	Cell Line Info	Homo sapiens (Human)	-
293-Dual hSTING-R232	Cell Line Info	Homo sapiens (Human)	-
HEK293-CNG	Cell Line Info	Homo sapiens (Human)	-
FreeStyle 293-F	Cell Line Info	Homo sapiens (Human)	-
PrecisION hnAChR alpha7/ric3-HEK	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer ERbeta-UAS-bla GripTite 293	Cell Line Info	Homo sapiens (Human)	-
HEK385-7	Cell Line Info	Homo sapiens (Human)	-
HEK2935	Cell Line Info	Homo sapiens (Human)	-
ACTOne CXCR4	Cell Line Info	Homo sapiens (Human)	-
HEK298	Cell Line Info	Homo sapiens (Human)	-
HEK273	Cell Line Info	Homo sapiens (Human)	-
293/GFP	Cell Line Info	Homo sapiens (Human)	-
HEK293 AequoScreen	Cell Line Info	Homo sapiens (Human)	-
HEK-Blue Null1-v	Cell Line Info	Homo sapiens (Human)	-
HEK-GIRK-M4	Cell Line Info	Homo sapiens (Human)	-
HTLA	Cell Line Info	Homo sapiens (Human)	-
HEK293/Galpha15	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-hH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-mH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
293AD	Cell Line Info	Homo sapiens (Human)	-
HEK293T/Galpha16-gustducin 44	Cell Line Info	Homo sapiens (Human)	-
CellSensor SBE-bla HEK 293T	Cell Line Info	Homo sapiens (Human)	-
NRK1-HEK293T	Cell Line Info	Homo sapiens (Human)	-
HEK293T-SF-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-rH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-mH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-beta-arr2-hH4R	Cell Line Info	Homo sapiens (Human)	-
HEK293T-SP-FLAG-hH3R-CRE-CBR	Cell Line Info	Homo sapiens (Human)	-
293/AP1-luc	Cell Line Info	Homo sapiens (Human)	-
293GT	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer AR-UAS-bla Griptite 293	Cell Line Info	Homo sapiens (Human)	-
UAS-MR-bla HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK293-DR-GFP	Cell Line Info	Homo sapiens (Human)	-
PSC-HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-293-A2B	Cell Line Info	Homo sapiens (Human)	-
HEK293-SF-rH4R-His6-CRE-Luc	Cell Line Info	Homo sapiens (Human)	-
Hana3A	Cell Line Info	Homo sapiens (Human)	-
HEK293S GnTI-	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla GripTite 293	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla HEK 293H	Cell Line Info	Homo sapiens (Human)	-
GeneBLAzer UAS-bla HEK 293T	Cell Line Info	Homo sapiens (Human)	-
HEKMSR2	Cell Line Info	Homo sapiens (Human)	-
HEK-hNET	Cell Line Info	Homo sapiens (Human)	-
HEK-hDAT	Cell Line Info	Homo sapiens (Human)	-
HEK-hSERT	Cell Line Info	Homo sapiens (Human)	-
EE-HEK293	Cell Line Info	Homo sapiens (Human)	-
HEK-A2A	Cell Line Info	Homo sapiens (Human)	-
HEK293EM	Cell Line Info	Homo sapiens (Human)	-
293-NB2	Cell Line Info	Homo sapiens (Human)	-
HEK-SEAP	Cell Line Info	Homo sapiens (Human)	-
HEK293/Gal4	Cell Line Info	Homo sapiens (Human)	-
Octn2-HEK	Cell Line Info	Homo sapiens (Human)	-
Octn1-HEK	Cell Line Info	Homo sapiens (Human)	-
Octn3-HEK	Cell Line Info	Homo sapiens (Human)	-
HEK293superTOP	Cell Line Info	Homo sapiens (Human)	-
HEK293T-ARRB1	Cell Line Info	Homo sapiens (Human)	-
HEK293T-ARRB2	Cell Line Info	Homo sapiens (Human)	-
HEK293T-qs5-HA	Cell Line Info	Homo sapiens (Human)	-
EDG3-Ga15-bla HEK293T	Cell Line Info	Homo sapiens (Human)	-
LLC-MK2	Cell Line Info	Macaca mulatta (Rhesus macaque)	-
BHK-21	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK-21 clone 13	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK570	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
TK-TS 13	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
BHK/AC9	Cell Line Info	Mesocricetus auratus (Golden hamster)	-
mIMCD-3	Cell Line Info	Mus musculus (Mouse)	-
RK3E	Cell Line Info	Rattus norvegicus (Rat)	-
KNRK	Cell Line Info	Rattus norvegicus (Rat)	-
SKPT-0193 Cl.2	Cell Line Info	Rattus norvegicus (Rat)	-
RKE	Cell Line Info	Rattus norvegicus (Rat)	-
LLC-PK1	Cell Line Info	Sus scrofa (Pig)	-
LLC-GA5-CoL150	Cell Line Info	Sus scrofa (Pig)	-
PK-15	Cell Line Info	Sus scrofa (Pig)	-
HKRK-B28	Cell Line Info	Sus scrofa (Pig)	-
PK15NTD	Cell Line Info	Sus scrofa (Pig)	-

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han