General Information of the Cell Line
Cell Line ID
CL000565
Cell Line Name
HEK-Blue CD40L
Category
Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_A8CE
Tissue Information
Kidney
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02347, Tumor necrosis factor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0135643
 Compound Info 
3-[(1R)-1-[[3-chloro-7-fluoro-6-[2-(2-hydroxypropan-2-yl)pyrimidin-5-yl]-2-methyl-1,5-naphthyridin-4-yl]amino]ethyl]-4-fluorobenzonitrile
   Show/Hide
C25H21ClF2N6O
  1
1
IC50 = 27 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0563803
 Compound Info 
2-[5-[4-[[(1R)-1-(5-amino-2-fluorophenyl)ethyl]amino]-3-chloroquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H23ClFN5O
  1
1
IC50 = 41 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497254
 Compound Info 
3-[(1R)-1-[[3-chloro-6-[2-(2-hydroxypropan-2-yl)pyrimidin-5-yl]quinolin-4-yl]amino]ethyl]-4-fluorobenzonitrile
   Show/Hide
C25H21ClFN5O
  1
1
IC50 = 49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557206
 Compound Info 
2-[5-[3-chloro-7-fluoro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H21ClF2N4O
  1
1
IC50 = 64 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564388
 Compound Info 
2-[4-[3-chloro-4-[[(1R)-1-(2-fluorophenyl)ethyl]amino]quinolin-6-yl]phenyl]propan-2-ol
   Show/Hide
C26H24ClFN2O
  1
1
IC50 = 65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0315218
 Compound Info 
5-[3-chloro-4-(2,5-dimethylanilino)quinolin-6-yl]pyridine-2-carbonitrile
   Show/Hide
C23H17ClN4
  1
1
IC50 = 73 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0135686
 Compound Info 
2-[5-[3-chloro-4-(2,5-dimethylanilino)quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H23ClN4O
  1
1
IC50 = 105 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0472975
 Compound Info 
2-[5-[4-(2,5-dimethylanilino)-3-methylquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C25H26N4O
  1
1
IC50 = 107 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513634
 Compound Info 
2-[5-[3-chloro-4-[[(1R)-1-(2-fluorophenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H22ClFN4O
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513638
 Compound Info 
2-[4-[5-[3-chloro-4-[[(1R)-1-(2-fluorophenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]piperazin-1-yl]acetic acid
   Show/Hide
C27H26ClFN6O2
  1
1
IC50 = 115 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0539915
 Compound Info 
3-chloro-6-[2-(1,1-dioxo-1,4-thiazinan-4-yl)pyrimidin-5-yl]-N-[(1R)-1-(2-fluorophenyl)ethyl]quinolin-4-amine
   Show/Hide
C25H23ClFN5O2S
  1
1
IC50 = 152 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497255
 Compound Info 
2-[5-[3,7-dichloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H21Cl2FN4O
  1
1
IC50 = 178 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0539914
 Compound Info 
2-[5-[3-chloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H22ClFN4O
  1
1
IC50 = 190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0315219
 Compound Info 
2-[5-[3-chloro-4-(2,5-dimethylanilino)-2-methylquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C25H25ClN4O
  1
1
IC50 = 196 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0190452
 Compound Info 
[1-[(2,5-dimethylphenyl)methyl]-6-(1-methylpyrazol-4-yl)benzimidazol-2-yl]-pyridin-4-ylmethanol
   Show/Hide
C26H25N5O
  1
1
IC50 = 202 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557233
 Compound Info 
2-[5-[3-chloro-8-fluoro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H21ClF2N4O
  1
1
IC50 = 224 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421562
 Compound Info 
2-[5-[3-chloro-4-[[(1R)-1-(2-fluoro-5-pyrrolidin-1-ylphenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C28H29ClFN5O
  1
1
IC50 = 331 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513639
 Compound Info 
2-[5-[3,5-dichloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H21Cl2FN4O
  1
1
IC50 = 365 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421561
 Compound Info 
2-[5-[3-chloro-4-[1-(2-fluorophenyl)propylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C25H24ClFN4O
  1
1
IC50 = 368 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557231
 Compound Info 
2-[5-[3-chloro-4-[1-[2-(trifluoromethyl)phenyl]ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C25H22ClF3N4O
  1
1
IC50 = 407 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556953
 Compound Info 
2-[5-[3-chloro-4-[[(1R)-1-phenylethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H23ClN4O
  1
1
IC50 = 496 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513637
 Compound Info 
3-chloro-6-(2-ethoxypyrimidin-5-yl)-N-[(1R)-1-(2-fluorophenyl)ethyl]quinolin-4-amine
   Show/Hide
C23H20ClFN4O
  1
1
IC50 = 587 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570382
 Compound Info 
2-[5-[3-chloro-4-[[1-(2-fluorophenyl)-2-methylpropyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C26H26ClFN4O
  1
1
IC50 = 826 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0472974
 Compound Info 
6-bromo-3-chloro-N-(2,5-dimethylphenyl)quinolin-4-amine
   Show/Hide
C17H14BrClN2
  1
1
IC50 = 840 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513635
 Compound Info 
2-[5-[3-chloro-4-[1-(4-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H22ClFN4O
  1
1
IC50 = 840 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550414
 Compound Info 
3-chloro-N-[(1R)-1-(2-fluorophenyl)ethyl]-6-(6-methylsulfonylpyridin-3-yl)quinolin-4-amine
   Show/Hide
C23H19ClFN3O2S
  1
1
IC50 = 909 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568290
 Compound Info 
2-[5-[3-chloro-4-[1-(3-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H22ClFN4O
  1
1
IC50 = 1037 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0135683
 Compound Info 
5-[4-(2,5-dimethylanilino)quinolin-6-yl]pyridine-2-carbonitrile
   Show/Hide
C23H18N4
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0421560
 Compound Info 
2-[5-[3-chloro-4-[[(1S)-1-phenylethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H23ClN4O
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513633
 Compound Info 
2-[5-[4-(benzylamino)-3-chloroquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C23H21ClN4O
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0539913
 Compound Info 
2-[5-[3-chloro-4-(2-phenylpropan-2-ylamino)quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C25H25ClN4O
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550413
 Compound Info 
2-[5-[3-chloro-4-(1-pyridin-2-ylethylamino)quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C23H22ClN5O
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557232
 Compound Info 
2-[5-[3,8-dichloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C24H21Cl2FN4O
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570383
 Compound Info 
2-[5-[4-[[(1R)-1-(2-fluoro-5-pyrrolidin-1-ylphenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
   Show/Hide
C28H30FN5O
  1
1
IC50 > 25000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Kidney)
Cell Line Name Organism Disease
G-402
 Cell Line Info 
Homo sapiens (Human) Kidney neoplasm
A-498
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
786-O
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
SN12C
 Cell Line Info 
Homo sapiens (Human) Renal cell carcinoma
G-401
 Cell Line Info 
Homo sapiens (Human) Rhabdoid tumor of the kidney
AU-BEK
 Cell Line Info 
Bos taurus (Bovine) -
MDCK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-I
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-MDR1
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCKII-LE
 Cell Line Info 
Canis lupus familiaris (Dog) -
DK
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK2/BCRP
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-Net6
 Cell Line Info 
Canis lupus familiaris (Dog) -
MDCK-UT-A1-AQP1-YFP
 Cell Line Info 
Canis lupus familiaris (Dog) -
CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS-M6
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
OAT1-COS7
 Cell Line Info 
Chlorocebus aethiops (Green monkey) -
BS-C-1
 Cell Line Info 
Chlorocebus pygerythrus (Vervet monkey) -
Vero
 Cell Line Info 
Chlorocebus sabaeus (Green monkey) -
OK
 Cell Line Info 
Didelphis virginiana (North American opossum) -
HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293T
 Cell Line Info 
Homo sapiens (Human) -
tsA201
 Cell Line Info 
Homo sapiens (Human) -
HEK293-A
 Cell Line Info 
Homo sapiens (Human) -
T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human) -
Expi293F
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293S
 Cell Line Info 
Homo sapiens (Human) -
HEK293-F
 Cell Line Info 
Homo sapiens (Human) -
HEK293-EBNA1-6E
 Cell Line Info 
Homo sapiens (Human) -
AD-293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-H
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/17
 Cell Line Info 
Homo sapiens (Human) -
293T/ACE2 [Japan 2021]
 Cell Line Info 
Homo sapiens (Human) -
GripTite 293 MSR
 Cell Line Info 
Homo sapiens (Human) -
HL-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR8
 Cell Line Info 
Homo sapiens (Human) -
PathHunter HEK 293 EDG1 Total GPCR Internalization
 Cell Line Info 
Homo sapiens (Human) -
Flp-In-T-REx-293
 Cell Line Info 
Homo sapiens (Human) -
HEKR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue IL-6
 Cell Line Info 
Homo sapiens (Human) -
HK-2 [Human kidney]
 Cell Line Info 
Homo sapiens (Human) -
HEK293-FT
 Cell Line Info 
Homo sapiens (Human) -
HEK-2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR4
 Cell Line Info 
Homo sapiens (Human) -
Expi293F GnTI-
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hNOD1
 Cell Line Info 
Homo sapiens (Human) -
pEAK Rapid
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR9
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue hTLR7
 Cell Line Info 
Homo sapiens (Human) -
293Ta
 Cell Line Info 
Homo sapiens (Human) -
293-Dual hSTING-R232
 Cell Line Info 
Homo sapiens (Human) -
HEK293-CNG
 Cell Line Info 
Homo sapiens (Human) -
FreeStyle 293-F
 Cell Line Info 
Homo sapiens (Human) -
PrecisION hnAChR alpha7/ric3-HEK
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer ERbeta-UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
HEK385-7
 Cell Line Info 
Homo sapiens (Human) -
HEK2935
 Cell Line Info 
Homo sapiens (Human) -
ACTOne CXCR4
 Cell Line Info 
Homo sapiens (Human) -
HEK298
 Cell Line Info 
Homo sapiens (Human) -
HEK273
 Cell Line Info 
Homo sapiens (Human) -
293/GFP
 Cell Line Info 
Homo sapiens (Human) -
HEK293 AequoScreen
 Cell Line Info 
Homo sapiens (Human) -
HEK-Blue Null1-v
 Cell Line Info 
Homo sapiens (Human) -
HEK-GIRK-M4
 Cell Line Info 
Homo sapiens (Human) -
HTLA
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Galpha15
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-hH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-mH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
293AD
 Cell Line Info 
Homo sapiens (Human) -
HEK293T/Galpha16-gustducin 44
 Cell Line Info 
Homo sapiens (Human) -
CellSensor SBE-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
NRK1-HEK293T
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SF-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-rH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-mH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-beta-arr2-hH4R
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-SP-FLAG-hH3R-CRE-CBR
 Cell Line Info 
Homo sapiens (Human) -
293/AP1-luc
 Cell Line Info 
Homo sapiens (Human) -
293GT
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer AR-UAS-bla Griptite 293
 Cell Line Info 
Homo sapiens (Human) -
UAS-MR-bla HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK293-DR-GFP
 Cell Line Info 
Homo sapiens (Human) -
PSC-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-293-A2B
 Cell Line Info 
Homo sapiens (Human) -
HEK293-SF-rH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human) -
Hana3A
 Cell Line Info 
Homo sapiens (Human) -
HEK293S GnTI-
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla GripTite 293
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293H
 Cell Line Info 
Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293T
 Cell Line Info 
Homo sapiens (Human) -
HEKMSR2
 Cell Line Info 
Homo sapiens (Human) -
HEK-hNET
 Cell Line Info 
Homo sapiens (Human) -
HEK-hDAT
 Cell Line Info 
Homo sapiens (Human) -
HEK-hSERT
 Cell Line Info 
Homo sapiens (Human) -
EE-HEK293
 Cell Line Info 
Homo sapiens (Human) -
HEK-A2A
 Cell Line Info 
Homo sapiens (Human) -
HEK293EM
 Cell Line Info 
Homo sapiens (Human) -
293-NB2
 Cell Line Info 
Homo sapiens (Human) -
HEK-SEAP
 Cell Line Info 
Homo sapiens (Human) -
HEK293/Gal4
 Cell Line Info 
Homo sapiens (Human) -
Octn2-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn1-HEK
 Cell Line Info 
Homo sapiens (Human) -
Octn3-HEK
 Cell Line Info 
Homo sapiens (Human) -
HEK293superTOP
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB1
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-ARRB2
 Cell Line Info 
Homo sapiens (Human) -
HEK293T-qs5-HA
 Cell Line Info 
Homo sapiens (Human) -
EDG3-Ga15-bla HEK293T
 Cell Line Info 
Homo sapiens (Human) -
LLC-MK2
 Cell Line Info 
Macaca mulatta (Rhesus macaque) -
BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK-21 clone 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK570
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
TK-TS 13
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
BHK/AC9
 Cell Line Info 
Mesocricetus auratus (Golden hamster) -
mIMCD-3
 Cell Line Info 
Mus musculus (Mouse) -
RK3E
 Cell Line Info 
Rattus norvegicus (Rat) -
KNRK
 Cell Line Info 
Rattus norvegicus (Rat) -
NRK-52E
 Cell Line Info 
Rattus norvegicus (Rat) -
SKPT-0193 Cl.2
 Cell Line Info 
Rattus norvegicus (Rat) -
RKE
 Cell Line Info 
Rattus norvegicus (Rat) -
LLC-PK1
 Cell Line Info 
Sus scrofa (Pig) -
LLC-GA5-CoL150
 Cell Line Info 
Sus scrofa (Pig) -
PK-15
 Cell Line Info 
Sus scrofa (Pig) -
HKRK-B28
 Cell Line Info 
Sus scrofa (Pig) -
PK15NTD
 Cell Line Info 
Sus scrofa (Pig) -