| Compound ID |
Compound Name |
Compound Formula |
|
CP0095515
|
(2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H20FN3O3S
|
4
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 2 nM
|
|
|
| 3 |
IC50 = 4 nM
|
|
|
| 4 |
IC50 = 6 nM
|
|
|
|
CP0406054
|
3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N-methylpropan-1-amine
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|
C16H18FN3O2S
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 2.7 nM
|
|
|
|
CP0489428
|
4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N-methylbutan-1-amine
Show/Hide
|
C17H20FN3O2S
|
2
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 4.5 nM
|
|
|
|
CP0706370
|
(1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C20H25ClF2N2O
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 5.5 nM
|
|
|
|
CP0706369
|
(1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride
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|
C20H26ClFN2O
|
2
|
| 1 |
IC50 = 1.6 nM
|
|
|
| 2 |
IC50 = 2.7 nM
|
|
|
|
CP0161683
|
(2S)-(4-[3-(2,5-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H19F2N3O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0258969
|
(2S)-4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)-1-(methylamino)butan-2-ol
Show/Hide
|
C17H21N3O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0317854
|
(2S)-(4-[3-(2,6-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H19F2N3O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0400590
|
3-[1-(2-fluorophenyl)-2,2-dioxo-2lambda6,1,3-benzothiadiazol-3-yl]-N-methylbutan-1-amine
Show/Hide
|
C17H20FN3O2S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
|
CP0435151
|
4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)-1-(methylamino)butan-2-one
Show/Hide
|
C17H18FN3O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 5.1 nM
|
|
|
|
CP0901042
|
4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H20FN3O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0520940
|
4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)-1-(methylamino)butan-2-ol
Show/Hide
|
C17H21N3O3S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0859701
|
(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(5-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride
Show/Hide
|
C19H24ClFN2O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0652323
|
(1S,2R)-1-(3,3-Dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C20H26ClFN2O
|
2
|
| 1 |
IC50 = 2.6 nM
|
|
|
| 2 |
IC50 = 6.3 nM
|
|
|
|
CP0051283
|
ATOMOXETINE
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|
C17H21NO
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 3.1 nM
|
|
|
|
CP0196465
|
(R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine
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|
C19H23NO3
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 3.2 nM
|
|
|
|
CP0859393
|
{3-[1-(2-Fluoro-phenyl)-2,2-dioxo-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl]-propyl}-methyl-amine hydrochloride
Show/Hide
|
C18H22ClFN2O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0375857
|
(2R)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H20FN3O3S
|
3
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
| 3 |
IC50 = 9 nM
|
|
|
|
CP0468601
|
(2R)-4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)-1-(methylamino)butan-2-ol
Show/Hide
|
C17H21N3O3S
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0083658
|
(S,S)-reboxetine
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|
C19H23NO3
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0055808
|
3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H22N2
|
4
|
| 1 |
IC50 = 3.3 nM
|
|
|
| 2 |
IC50 = 3.4 nM
|
|
|
| 3 |
Ki = 2.1 nM
|
|
|
| 4 |
Ki = 3.4 nM
|
|
|
|
CP0864120
|
(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-[(3R)-3-methyl-2,3-dihydro-1H-indol-1-yl]propan-2-ol Hydrochloride
Show/Hide
|
C19H24ClFN2O
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0008168
|
CAS_136434-34-9
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|
C18H19NOS
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0494695
|
(1S,2R)-1-(3-fluorophenyl)-1-(3-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0396969
|
1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-(3-fluorophenyl)-propyl]-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C19H21F2N3O2
|
2
|
| 1 |
IC50 = 4.1 nM
|
|
|
| 2 |
IC50 = 10.4 nM
|
|
|
|
CP0402590
|
4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3-(methylamino)-propyl]-1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C20H23F2N3O2
|
2
|
| 1 |
IC50 = 4.1 nM
|
|
|
| 2 |
IC50 = 6.9 nM
|
|
|
|
CP0652324
|
(1S,2R)-1-(3,5-Difluorophenyl)-1-(3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C20H25ClF2N2O
|
2
|
| 1 |
IC50 = 4.1 nM
|
|
|
| 2 |
IC50 = 6.5 nM
|
|
|
|
CP0845301
|
(1S,2R)-1-(2,3-Dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C18H22ClFN2O
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0859394
|
{3-[1-(2,6-Difluoro-phenyl)-2,2-dioxo-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl]-propyl}-methyl-amine hydrochloride
Show/Hide
|
C18H21ClF2N2O2S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0416558
|
3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N-methylbutan-2-amine
Show/Hide
|
C17H20FN3O2S
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 72 nM
|
|
|
|
CP0375858
|
1-[2-[(2R)-morpholin-2-yl]ethyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H21N3O3S
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0375860
|
3-(2-fluorophenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H20FN3O3S
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0498694
|
4-fluoro-1-(2-fluorophenyl)-3-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H19F2N3O3S
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0706368
|
(1S,2R)-1-(3,3-Dimethyl-2,3-dihydro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride
Show/Hide
|
C20H27ClN2O
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0521188
|
(R)-4-fluoro-1-(2-fluorophenyl)-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C23H21F2N3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0416557
|
(2R)-(4-[3-(2,6-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H19F2N3O3S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0853151
|
(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(3-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride
Show/Hide
|
C19H24ClFN2O
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0402589
|
1-Ethyl-3-[1-(3-fluoro-phenyl)-2-hydroxy-3-methylamino-propyl]-1,3-dihydro-benzimidazol-2-one
Show/Hide
|
C19H22FN3O2
|
2
|
| 1 |
IC50 = 6.4 nM
|
|
|
| 2 |
IC50 = 7.4 nM
|
|
|
|
CP0418781
|
(1S,2R)-1-(7-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18F2N2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0458790
|
1-(2-morpholin-2-ylethyl)-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H21N3O3S
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 18 nM
|
|
|
|
CP0375863
|
4-fluoro-3-(2-fluorophenyl)-1-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H19F2N3O3S
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 13 nM
|
|
|
|
CP0859391
|
(1S,2R)-1-(5-Chloro-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C18H21Cl2FN2O
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0402588
|
4-Fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C20H24FN3O2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0401535
|
(2S)-(4-[3-(2-Chlorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H20ClN3O3S
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
|
CP0375862
|
5-fluoro-1-(2-fluorophenyl)-3-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H19F2N3O3S
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 14 nM
|
|
|
|
CP0853149
|
(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-[(3S)-3-methyl-2,3-dihydro-1H-indol-1-yl]propan-2-ol Hydrochloride
Show/Hide
|
C19H24ClFN2O
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0419035
|
(R)-1-(3-(methylamino)-1-phenylpropyl)-3-phenyl-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C23H23N3O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0493656
|
1-(Cyclopropylamino)-4-(2,2-dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)butan-2-ol
Show/Hide
|
C19H23N3O3S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0458791
|
1-[2-[(2S)-morpholin-2-yl]ethyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H21N3O3S
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 13 nM
|
|
|
|
CP0845289
|
(1S,2R)-1-(2,3-Dihydro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride
Show/Hide
|
C18H23ClN2O
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0418749
|
(1S,2R)-1-(3-ethyl-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C20H23FN2O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0452247
|
(2R)-(4-[3-(2,5-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H19F2N3O3S
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
|
|
CP0431069
|
1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropyl]-3-isopropyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C20H25N3O2
|
2
|
| 1 |
IC50 = 10.8 nM
|
|
|
| 2 |
IC50 = 13.4 nM
|
|
|
|
CP0496252
|
(1S,2R)-1-(3-fluorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19FN2O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0859395
|
{3-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl]-propyl}-methyl-amine hydrochloride
Show/Hide
|
C18H21ClF2N2O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0372540
|
1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C19H22FN3O2
|
2
|
| 1 |
IC50 = 11.4 nM
|
|
|
| 2 |
IC50 = 13.8 nM
|
|
|
|
CP0417365
|
(1S,2R)-1-(3-fluorophenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C17H21FN2O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0447754
|
3-(phenylsulfonyl)-1H-indole, 33b
Show/Hide
|
C20H24N2O2S
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0853062
|
[3-(2,2-Dioxo-1-phenyl-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl)-propyl]-methyl-amine hydrochloride
Show/Hide
|
C18H23ClN2O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0375856
|
(2R)-4-(2,2-dioxo-3-phenyl-2lambda6,1,3-benzothiadiazol-1-yl)-2-methoxy-N-methylbutan-1-amine
Show/Hide
|
C18H23N3O3S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 27 nM
|
|
|
|
CP0401545
|
(1S,2R)-1-(3-bromophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19BrN2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0853046
|
(1S,2R)-1-(3-Ethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C20H26ClFN2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0496259
|
(1S,2R)-1-(3-fluorophenyl)-1-(4-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0902378
|
(1S,2R)-1-[5-(Benzyloxy)-2,3-dihydro-1H-indol-1-yl]-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C25H28ClFN2O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0388214
|
(1S,2R)-1-(3-chlorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0496254
|
(1S,2R)-1-(4-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18F2N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0372520
|
1-Ethyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one
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C19H23N3O2
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2
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| 1 |
IC50 = 16.8 nM
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| 2 |
IC50 = 17.5 nM
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CP0845208
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(1S,2R)-1-(6-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
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C20H25ClF2N2O
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1
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| 1 |
IC50 = 17 nM
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CP0431022
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(1S,2R)-1-(3-fluorophenyl)-1-(7-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol
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C19H21FN2O
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1
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| 1 |
IC50 = 18 nM
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CP0400591
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(2S)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
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C17H19F2N3O3S
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2
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| 1 |
IC50 = 18 nM
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| 2 |
IC50 = 19 nM
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CP0402585
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1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropyl]-3-propyl-1,3-dihydro-2H-benzimidazol-2-one
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C20H25N3O2
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1
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| 1 |
IC50 = 18.6 nM
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CP0474690
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(R)-1-ethyl-4-fluoro-3-(1-(3-fluorophenyl)-3-(methylamino)propyl)-1H-benzo[d]imidazol-2(3H)-one
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C19H21F2N3O
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1
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| 1 |
IC50 = 19 nM
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CP0401508
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(2S)-(4-[3-(3-Methoxyphenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
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C18H23N3O4S
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2
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| 1 |
IC50 = 19 nM
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| 2 |
IC50 = 25 nM
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CP0853047
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(1S,2R)-1-(5-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
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C20H25ClF2N2O
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1
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| 1 |
IC50 = 19 nM
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CP0422130
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(R,S/S,R)-syn-1-((3-chlorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
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C17H21ClN2O
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1
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| 1 |
IC50 = 20 nM
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CP0496253
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(1S,2R)-1-(6-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
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C18H18F2N2O
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1
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| 1 |
IC50 = 20 nM
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CP0431021
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(1S,2R)-1-(7-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
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C18H18BrFN2O
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1
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| 1 |
IC50 = 21 nM
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CP0443265
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(1S,2R)-1-(3-fluorophenyl)-1-(5-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol
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C19H21FN2O
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1
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| 1 |
IC50 = 21 nM
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CP0443266
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(1S,2R)-1-(7-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
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C18H18ClFN2O
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1
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| 1 |
IC50 = 21 nM
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CP0853153
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(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro[cyclopentane-1,3'-indol]-1'(2'H)-ylpropan-2-ol Hydrochloride
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C22H28ClFN2O
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1
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| 1 |
IC50 = 21 nM
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CP0474691
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(R)-1-isopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
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C20H25N3O
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1
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| 1 |
IC50 = 22 nM
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CP0494697
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(1S,2R)-1-(5-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
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C18H18F2N2O
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1
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| 1 |
IC50 = 22 nM
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CP0388267
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(2S)-(4-[3-(2-Methylphenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
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C18H23N3O3S
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2
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| 1 |
IC50 = 22 nM
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| 2 |
IC50 = 64 nM
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CP0439587
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(R,S/S,R)-syn-1-((4-chlorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
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C17H21ClN2O
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1
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| 1 |
IC50 = 23 nM
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CP0899678
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(1S,2R)-1-(3-Fluorophenyl)-1-(3-isopropyl-2,3-dihydro-1Hindol-1-yl)-3-(methylamino)propan-2-ol Hydrochloride
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C21H28ClFN2O
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1
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| 1 |
IC50 = 23 nM
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CP0850318
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(+)-1-[(1S)-1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
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C18H29Cl3N2O
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2
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| 1 |
IC50 = 25 nM
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| 2 |
Ki = 17 nM
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CP0447447
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3-[1-(2,6-difluorophenyl)-6-fluoro-2,2-dioxo-3,4-dihydro-2lambda6,1-benzothiazin-3-yl]-N-methylpropan-1-amine
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C18H19F3N2O2S
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1
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| 1 |
IC50 = 25 nM
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CP0880381
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[3-(6-Fluoro-2,2-dioxo-1-phenyl-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl)-propyl]-methyl-amine hydrochloride
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C18H22ClFN2O2S
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1
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| 1 |
IC50 = 26 nM
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CP0885041
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{3-[1-(2,6-Difluoro-phenyl)-6-fluoro-2,2-dioxo-1,2,3,4-tetrahydro-2lambda*6*-benzo[c][1,2]thiazin-3-yl]-propyl}-methyl-amine hydrochloride
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C18H20ClF3N2O2S
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1
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| 1 |
IC50 = 27 nM
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CP0089680
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(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
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C18H20N2O
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1
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| 1 |
IC50 = 28 nM
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CP0435003
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(R,S/S,R)-syn-1-(methyl(p-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
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C18H24N2O
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1
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| 1 |
IC50 = 29 nM
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CP0504422
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3-(phenylsulfonyl)-1H-indole, 33a
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C20H24N2O2S
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2
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| 1 |
IC50 = 29 nM
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| 2 |
Ki = 21 nM
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CP0915874
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(-)-1-[(1S)-1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
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C19H31Cl3N2O
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2
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| 1 |
IC50 = 29 nM
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| 2 |
Ki = 14 nM
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CP0401458
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3-[1-(2-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
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C17H20FN3O2S
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1
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| 1 |
IC50 = 29 nM
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CP0490690
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(R,S/S,R)-syn-1-(methyl(phenyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
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C17H22N2O
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1
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| 1 |
IC50 = 30 nM
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CP0374270
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(R)-4-fluoro-1-isopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
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C20H24FN3O
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1
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| 1 |
IC50 = 30 nM
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CP0509603
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4-[6-fluoro-1-(2-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylbutan-1-amine
Show/Hide
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C18H21F2N3O2S
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1
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| 1 |
IC50 = 30 nM
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CP0479839
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(-)-1-[(1S)-1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
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C19H29ClN2O
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1
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| 1 |
IC50 = 30 nM
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CP0375853
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3-phenyl-1-(2-piperidin-3-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide
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C19H23N3O2S
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2
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| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 54 nM
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CP0437722
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(R)-1-(3-(methylamino)-1-phenylpropyl)-3-propyl-1H-benzo[d]imidazol-2(3H)-one
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C20H25N3O
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1
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| 1 |
IC50 = 32 nM
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CP0378521
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1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)ethyl)cyclohexanol
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C17H24F3NO
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2
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| 1 |
IC50 = 32 nM
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| 2 |
Ki = 21 nM
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CP0435005
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(R,S/S,R)-syn-1-(4-methoxyphenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol
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C18H24N2O2
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1
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| 1 |
IC50 = 34 nM
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CP0441310
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(R)-3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine
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C18H20N2
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1
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| 1 |
IC50 = 34 nM
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CP0388276
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(2S)-(4-[3-(3,4-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
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C17H19F2N3O3S
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2
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| 1 |
IC50 = 36 nM
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| 2 |
IC50 = 43 nM
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CP0396970
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1-Ethyl-5-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one
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C19H22FN3O2
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1
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| 1 |
IC50 = 36.7 nM
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CP0851787
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1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
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C18H29Cl3N2O
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2
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| 1 |
IC50 = 38 nM
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| 2 |
Ki = 18 nM
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CP0447448
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4-[1-(2-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylbutan-1-amine
Show/Hide
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C18H22FN3O2S
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1
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| 1 |
IC50 = 38 nM
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CP0845300
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(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro[cyclohexane-1,30-indol]-1'(2'H)-ylpropan-2-ol Hydrochloride
Show/Hide
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C23H30ClFN2O
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1
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| 1 |
IC50 = 39 nM
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CP0502454
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5-Fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1-propyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
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C20H24FN3O2
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1
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| 1 |
IC50 = 39.4 nM
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CP0463763
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(+/-)-Erythro--1-(3-methyl-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
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C19H22N2O
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1
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| 1 |
IC50 = 42 nM
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CP0402586
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1-Cyclobutyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
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C21H25N3O2
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2
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| 1 |
IC50 = 42.5 nM
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| 2 |
IC50 = 90 nM
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CP0474688
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(R)-1-ethyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
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C19H23N3O
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1
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| 1 |
IC50 = 44 nM
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CP0375154
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(-)-1-[(1R)-1-(3-Chlorophenyl)-2-(dimethylamino)ethyl]cyclohexanol
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C16H24ClNO
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2
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| 1 |
IC50 = 46 nM
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| 2 |
Ki = 41 nM
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CP0374268
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3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine
Show/Hide
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C18H20N2
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1
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| 1 |
IC50 = 47 nM
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CP0417789
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3-(phenylsulfonyl)-1H-indole, 18i
Show/Hide
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C21H24N2O2S
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2
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| 1 |
IC50 = 47 nM
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| 2 |
Ki = 27 nM
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CP0401331
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(2R)-(4-[3-(2-Chlorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H20ClN3O3S
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2
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| 1 |
IC50 = 48 nM
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| 2 |
IC50 = 61 nM
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CP0439023
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3-(phenylsulfonyl)-1H-indole, 18b
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C19H22N2O2S
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2
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| 1 |
IC50 = 49 nM
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| 2 |
Ki = 28 nM
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CP0401546
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(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-tolylpropan-2-ol
Show/Hide
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C19H22N2O
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1
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| 1 |
IC50 = 49 nM
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CP0491216
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(+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
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C18H19ClN2O
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1
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| 1 |
IC50 = 49 nM
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CP0417788
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3-(phenylsulfonyl)-1H-indole, 18f
Show/Hide
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C19H22N2O2S
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2
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| 1 |
IC50 = 51 nM
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| 2 |
Ki = 25 nM
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CP0388277
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(2S)-(4-[3-(4-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
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C17H20FN3O3S
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2
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| 1 |
IC50 = 51 nM
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| 2 |
IC50 = 146 nM
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CP0501006
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(1S,2R)-1-(4-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
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C18H18BrFN2O
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1
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| 1 |
IC50 = 52 nM
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CP0440185
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3-[1-(2,6-difluorophenyl)-2,2-dioxo-3,4-dihydro-2lambda6,1-benzothiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C18H20F2N2O2S
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1
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| 1 |
IC50 = 52 nM
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CP0443267
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(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-(3-(trifluoromethyl)phenyl)propan-2-ol
Show/Hide
|
C19H19F3N2O
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1
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| 1 |
IC50 = 54 nM
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CP0401459
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3-[1-(2-fluorophenyl)-2,2-dioxo-3,4-dihydro-2lambda6,1-benzothiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C18H21FN2O2S
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1
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| 1 |
IC50 = 55 nM
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CP0396971
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1-t-Butyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C21H27N3O2
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1
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| 1 |
IC50 = 56 nM
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CP0401456
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1-[1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
Show/Hide
|
C19H29ClN2O
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1
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| 1 |
IC50 = 56 nM
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CP0373537
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(2R)-3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N,2-dimethylpropan-1-amine
Show/Hide
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C17H20FN3O2S
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2
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| 1 |
IC50 = 57 nM
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| 2 |
IC50 = 305 nM
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CP0401453
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(+)-S-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpiperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C17H27ClN2OS
|
1
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| 1 |
IC50 = 57 nM
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CP0851788
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1-[1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
Show/Hide
|
C19H31Cl3N2O
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2
|
| 1 |
IC50 = 58 nM
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| 2 |
Ki = 46 nM
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CP0472054
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(1S,2R)-1-(5-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18BrFN2O
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1
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| 1 |
IC50 = 60 nM
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CP0496260
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(1S,2R)-1-(5-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18ClFN2O
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1
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| 1 |
IC50 = 60 nM
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CP0417466
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(R,S/S,R)-syn-1-(methyl(m-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H24N2O
|
1
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| 1 |
IC50 = 61 nM
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CP0435004
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(R,S/S,R)-syn-1-((4-fluorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C17H21FN2O
|
1
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| 1 |
IC50 = 62 nM
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CP0418750
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(1S,2R)-1-(4-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18ClFN2O
|
1
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| 1 |
IC50 = 64 nM
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CP0402587
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1-Cyclopentyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C22H27N3O2
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1
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| 1 |
IC50 = 66.7 nM
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CP0509911
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(R,S/S,R)-syn-3-amino-1-(methyl(phenyl)amino)-1-phenylpropan-2-ol
Show/Hide
|
C16H20N2O
|
1
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| 1 |
IC50 = 68 nM
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CP0864119
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(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride
Show/Hide
|
C19H24ClFN2O
|
1
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| 1 |
IC50 = 72 nM
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CP0493734
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(R,S/S,R)-syn-1-(3-chlorophenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C17H21ClN2O
|
1
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| 1 |
IC50 = 73 nM
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CP0846665
|
rac-1-(Morpholin-2-ylmethyl)-3-phenyl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-Dioxide
Show/Hide
|
C17H19N3O3S
|
2
|
| 1 |
IC50 = 74 nM
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| 2 |
IC50 = 147 nM
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CP0485558
|
(2S,3R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-olHydrochloride
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0497164
|
3-(phenylsulfonyl)-1H-indole, 18a
Show/Hide
|
C18H20N2O2S
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
Ki = 45 nM
|
|
|
|
CP0505765
|
(2R)-(4-[3-(3-Methoxyphenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C18H23N3O4S
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 143 nM
|
|
|
|
CP0375861
|
1-[2-[(2R)-morpholin-2-yl]ethyl]-3-(2,4,6-trifluorophenyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H18F3N3O3S
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 91 nM
|
|
|
|
CP0742803
|
(-)-1-{(1S)-2-(4-Methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride
Show/Hide
|
C20H31Cl2F3N2O2
|
2
|
| 1 |
IC50 = 82 nM
|
|
|
| 2 |
Ki = 50 nM
|
|
|
|
CP0443274
|
(1S,2R)-1-(4-fluorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19FN2O
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0514773
|
3-(2,2-dioxo-1-phenyl-3,4-dihydro-2lambda6,1-benzothiazin-3-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H22N2O2S
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0494415
|
3-(3-methoxyphenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C19H23N3O4S
|
2
|
| 1 |
IC50 = 89 nM
|
|
|
| 2 |
IC50 = 99 nM
|
|
|
|
CP0418751
|
(R)-3-(3-fluorophenyl)-3-(1H-indol-1-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H19FN2
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0402584
|
4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3-(methylamino)propyl]-1-phenyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C23H21F2N3O2
|
1
|
| 1 |
IC50 = 91.9 nM
|
|
|
|
CP0845952
|
1-{2-(3-Methylpiperazin-1-yl)-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol Dihydrocholoride
Show/Hide
|
C20H31Cl2F3N2O
|
2
|
| 1 |
IC50 = 92 nM
|
|
|
| 2 |
Ki = 61 nM
|
|
|
|
CP0418923
|
(1S,2R)-1-(6-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18ClFN2O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0499128
|
(1S,2R)-1-(2-fluorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19FN2O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0502458
|
3-[6-fluoro-1-(2-fluorophenyl)-2,2-dioxo-3,4-dihydro-2lambda6,1-benzothiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C18H20F2N2O2S
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0845945
|
1-{2-Piperazin-1-yl-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol Dihydrochloride
Show/Hide
|
C19H29Cl2F3N2O
|
2
|
| 1 |
IC50 = 94 nM
|
|
|
| 2 |
Ki = 58 nM
|
|
|
|
CP0470991
|
2,2-Difluoro-3-[3-(2-fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N-methylpropan-1-amine
Show/Hide
|
C16H16F3N3O2S
|
2
|
| 1 |
IC50 = 94 nM
|
|
|
| 2 |
IC50 = 238 nM
|
|
|
|
CP0851224
|
1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpiperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C17H27ClN2OS
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0431099
|
(R,S/S,R)-syn-1-((4-methoxyphenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H24N2O2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0452154
|
(2R)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H19F2N3O3S
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 109 nM
|
|
|
|
CP0469049
|
1-(1-(5-chlorothiophen-3-yl)-2-(piperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C16H25ClN2OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0375852
|
(2S)-4-(2,2-dioxo-3-phenyl-2lambda6,1,3-benzothiadiazol-1-yl)-2-methoxy-N-methylbutan-1-amine
Show/Hide
|
C18H23N3O3S
|
2
|
| 1 |
IC50 = 103 nM
|
|
|
| 2 |
IC50 = 151 nM
|
|
|
|
CP0915599
|
(2S,3R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride
Show/Hide
|
C18H21ClN2O
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0417468
|
(R,S/S,R)-syn-1-(4-chlorophenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C17H21ClN2O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0494683
|
(1S,2R)-1-(1H-indol-1-yl)-1-(3-methoxyphenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0400065
|
3-(phenylsulfonyl)-1H-indole, 18k
Show/Hide
|
C22H26N2O2S
|
2
|
| 1 |
IC50 = 116 nM
|
|
|
| 2 |
Ki = 125 nM
|
|
|
|
CP0494696
|
(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-p-tolylpropan-2-ol
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0433747
|
(+/-)-Erythro--1-(5-fluoro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H19FN2O
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0372302
|
(R,S/S,R)-syn-1-(methyl(naphthalen-1-yl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0388179
|
1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol
Show/Hide
|
C16H24ClNO
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
Ki = 249 nM
|
|
|
|
CP0440183
|
3-[6-fluoro-1-(2-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C17H19F2N3O2S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0501282
|
5-fluoro-3-(2-fluorophenyl)-1-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H19F2N3O3S
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 209 nM
|
|
|
|
CP0479027
|
(R)-3-(3-(methylamino)-1-phenylpropyl)benzo[d]thiazol-2(3H)-one
Show/Hide
|
C17H18N2OS
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0376294
|
1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol
Show/Hide
|
C16H24ClNO
|
2
|
| 1 |
IC50 = 121 nM
|
|
|
| 2 |
Ki = 149 nM
|
|
|
|
CP0494694
|
(1S,2R)-1-(6-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H18BrFN2O
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0447752
|
3-(phenylsulfonyl)-1H-indole, 18h
Show/Hide
|
C20H22N2O2S
|
2
|
| 1 |
IC50 = 128 nM
|
|
|
| 2 |
Ki = 73 nM
|
|
|
|
CP0514769
|
3-(2,2-dioxo-1-phenyl-4H-2lambda6,1,3-benzothiadiazin-3-yl)-N-methylpropan-1-amine
Show/Hide
|
C17H21N3O2S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0852056
|
(+)-1-{(1S)-2-Piperazin-1-yl-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrochloride
Show/Hide
|
C19H29Cl2F3N2O2
|
2
|
| 1 |
IC50 = 140 nM
|
|
|
| 2 |
Ki = 117 nM
|
|
|
|
CP0514770
|
N-methyl-3-[1-(4-methylphenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]propan-1-amine
Show/Hide
|
C18H23N3O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0458793
|
3-(2,4-difluorophenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H19F2N3O3S
|
2
|
| 1 |
IC50 = 143 nM
|
|
|
| 2 |
IC50 = 199 nM
|
|
|
|
CP0497161
|
3-(phenylsulfonyl)-1H-indole, 18d
Show/Hide
|
C18H20N2O2S
|
2
|
| 1 |
IC50 = 146 nM
|
|
|
| 2 |
Ki = 78 nM
|
|
|
|
CP0913775
|
1-{2-(3-Methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride
Show/Hide
|
C20H31Cl2F3N2O2
|
2
|
| 1 |
IC50 = 147 nM
|
|
|
| 2 |
Ki = 91 nM
|
|
|
|
CP0419033
|
(1R,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0853152
|
(1S,2R)-1-(3,3-Diethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride
Show/Hide
|
C22H30ClFN2O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0468605
|
(2R)-(4-[3-(2-Methylphenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C18H23N3O3S
|
2
|
| 1 |
IC50 = 155 nM
|
|
|
| 2 |
IC50 = 294 nM
|
|
|
|
CP0399898
|
(R,S/S,R)-syn-3-amino-1-(4-methoxyphenyl)-1-(methyl(phenyl)amino)propan-2-ol
Show/Hide
|
C17H22N2O2
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0491818
|
(R)-1-cyclopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C20H23N3O
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0390209
|
3-(6-fluoro-2,2-dioxo-1-phenyl-3,4-dihydro-2lambda6,1-benzothiazin-3-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H21FN2O2S
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0845299
|
(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(7-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride
Show/Hide
|
C19H24ClFN2O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0406190
|
4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)-1-(ethylamino)butan-2-ol
Show/Hide
|
C18H23N3O3S
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0375855
|
1-[[(2S)-morpholin-2-yl]methyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C17H19N3O3S
|
1
|
| 1 |
IC50 = 199 nM
|
|
|
|
CP0401457
|
2-[1-(2-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylethanamine
Show/Hide
|
C16H18FN3O2S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0474689
|
(R)-1-cyclopentyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
IC50 = 201 nM
|
|
|
|
CP0386060
|
1-(1-(2-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol
Show/Hide
|
C16H24ClNO
|
2
|
| 1 |
IC50 = 205 nM
|
|
|
| 2 |
Ki = 125 nM
|
|
|
|
CP0458792
|
1-[[(2R)-morpholin-2-yl]methyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C17H19N3O3S
|
1
|
| 1 |
IC50 = 207 nM
|
|
|
|
CP0375158
|
1-(2-(dimethylamino)-1-(3-methoxyphenyl)ethyl)cyclohexanol
Show/Hide
|
C17H27NO2
|
2
|
| 1 |
IC50 = 208 nM
|
|
|
| 2 |
Ki = 316 nM
|
|
|
|
CP0491820
|
(S)-1-(3-(methylamino)-1-phenylpropyl)-3-phenyl-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C23H23N3O
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0372303
|
(1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H24N2O
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0506468
|
3-(phenylsulfonyl)-1H-indole, 18j
Show/Hide
|
C22H26N2O2S
|
2
|
| 1 |
IC50 = 221 nM
|
|
|
| 2 |
Ki = 208 nM
|
|
|
|
CP0383501
|
1-(1-(2,5-dichlorothiophen-3-yl)-2-(piperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C16H24Cl2N2OS
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0398544
|
(+/-)-Erythro--1-(5-methoxy-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0439109
|
(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-o-tolylpropan-2-ol
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 = 232 nM
|
|
|
|
CP0485443
|
(R,S/S,R)-syn-1-((2-chlorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C17H21ClN2O
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0893145
|
1-[1-(3-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
Show/Hide
|
C19H31Cl2FN2O
|
2
|
| 1 |
IC50 = 240 nM
|
|
|
| 2 |
Ki = 364 nM
|
|
|
|
CP0373561
|
(2R)-(4-[3-(4-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H20FN3O3S
|
2
|
| 1 |
IC50 = 244 nM
|
|
|
| 2 |
IC50 = 328 nM
|
|
|
|
CP0386420
|
1-(1-(benzo[b]thiophen-3-yl)-2-(piperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C20H28N2OS
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0472122
|
1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropyl]-3-methyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
IC50 = 257 nM
|
|
|
|
CP0504037
|
(2R)-(4-[3-(3,4-Difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol
Show/Hide
|
C17H19F2N3O3S
|
2
|
| 1 |
IC50 = 277 nM
|
|
|
| 2 |
IC50 = 394 nM
|
|
|
|
CP0375859
|
3-(4-fluorophenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H20FN3O3S
|
2
|
| 1 |
IC50 = 283 nM
|
|
|
| 2 |
IC50 = 611 nM
|
|
|
|
CP0850315
|
1-{2-Piperazin-1-yl-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrochloride
Show/Hide
|
C19H29Cl2F3N2O2
|
2
|
| 1 |
IC50 = 284 nM
|
|
|
| 2 |
Ki = 140 nM
|
|
|
|
CP0435002
|
(R,S/S,R)-syn-1-((2-methoxyphenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H24N2O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0497162
|
3-(phenylsulfonyl)-1H-indole, 18e
Show/Hide
|
C19H22N2O2S
|
2
|
| 1 |
IC50 = 302 nM
|
|
|
| 2 |
Ki = 487 nM
|
|
|
|
CP0384697
|
(+)-1-[(1S)-1-(3-Chlorophenyl)-2-(dimethylamino)ethyl]cyclohexanol
Show/Hide
|
C16H24ClNO
|
2
|
| 1 |
IC50 = 303 nM
|
|
|
| 2 |
Ki = 339 nM
|
|
|
|
CP0496255
|
(1S,2R)-1-(2-chlorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
IC50 = 304 nM
|
|
|
|
CP0491819
|
(R)-1-cyclohexyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0455224
|
(+/-)-Erythro--3-amino-1-(3-methyl-1H-indol-1-yl)-1-phenylpropan-2-ol
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
IC50 = 321 nM
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|
|
CP0417787
|
3-(phenylsulfonyl)-1H-indole, 18c
Show/Hide
|
C17H18N2O2S
|
2
|
| 1 |
IC50 = 353 nM
|
|
|
| 2 |
Ki = 306 nM
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CP0372301
|
(R,S/S,R)-syn-1-((3-methoxyphenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H24N2O2
|
1
|
| 1 |
IC50 = 400 nM
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|
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|
CP0455225
|
(+/-)-Erythro-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
IC50 = 415 nM
|
|
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|
CP0388269
|
(2S)-3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N,2-dimethylpropan-1-amine
Show/Hide
|
C17H20FN3O2S
|
2
|
| 1 |
IC50 = 441 nM
|
|
|
| 2 |
IC50 = 602 nM
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|
|
CP0497163
|
3-(phenylsulfonyl)-1H-indole, 18g
Show/Hide
|
C21H24N2O2S
|
2
|
| 1 |
IC50 = 460 nM
|
|
|
| 2 |
Ki = 428 nM
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CP0374272
|
(R)-1-methyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
IC50 = 463 nM
|
|
|
|
CP0477730
|
1-(Dimethylamino)-4-(2,2-dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)butan-2-ol
Show/Hide
|
C18H23N3O3S
|
1
|
| 1 |
IC50 = 481 nM
|
|
|
|
CP0401454
|
3-[1-(4-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C17H20FN3O2S
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0501007
|
(1S,2R)-1-(4-chlorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
IC50 = 527 nM
|
|
|
|
CP0054778
|
CAS_93413-69-5
Show/Hide
|
C17H27NO2
|
2
|
| 1 |
IC50 = 535 nM
|
|
|
| 2 |
Ki = 385 nM
|
|
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|
CP0921911
|
(-)-1-[(1R)-1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C18H29Cl3N2O
|
2
|
| 1 |
IC50 = 540 nM
|
|
|
| 2 |
Ki = 214 nM
|
|
|
|
CP0522115
|
(R,S/S,R)-syn-3-amino-1-(3-fluorophenyl)-1-(methyl(phenyl)amino)propan-2-ol
Show/Hide
|
C16H19FN2O
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0383502
|
1-(1-(benzo[b]thiophen-2-yl)-2-(piperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C20H28N2OS
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0035258
|
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Show/Hide
|
C17H18F3NO
|
1
|
| 1 |
IC50 = 563 nM
|
|
|
|
CP0897101
|
1-{2-(4-Methylpiperazin-1-yl)-1-[4-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride
Show/Hide
|
C20H31Cl2F3N2O2
|
2
|
| 1 |
IC50 = 575 nM
|
|
|
| 2 |
Ki = 417 nM
|
|
|
|
CP0469050
|
(-)-R-1-(1-(3-chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C19H30ClN3
|
1
|
| 1 |
IC50 = 576 nM
|
|
|
|
CP0850316
|
(+)-1-[(1R)-1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
Show/Hide
|
C19H31Cl3N2O
|
2
|
| 1 |
IC50 = 577 nM
|
|
|
| 2 |
Ki = 187 nM
|
|
|
|
CP0845949
|
1-[1-(3-Methoxyphenyl)-2-(4-methyl-1-piperazinyl)ethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C20H34Cl2N2O2
|
2
|
| 1 |
IC50 = 600 nM
|
|
|
| 2 |
Ki = 514 nM
|
|
|
|
CP0374271
|
(S)-1-(3-(methylamino)-1-phenylpropyl)-3-propyl-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
IC50 = 627 nM
|
|
|
|
CP0407678
|
3-[1-(3-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C17H20FN3O2S
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0845948
|
1-[1-(3-Fluorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C18H29Cl2FN2O
|
2
|
| 1 |
IC50 = 673 nM
|
|
|
| 2 |
Ki = 368 nM
|
|
|
|
CP0447755
|
3-(phenylsulfonyl)-1H-indole, 33c
Show/Hide
|
C22H26N2O2S
|
2
|
| 1 |
IC50 = 707 nM
|
|
|
| 2 |
Ki = 1030 nM
|
|
|
|
CP0383499
|
1-(1-(2-chlorothiophen-3-yl)-2-(piperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C16H25ClN2OS
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0390206
|
3-[1-(3-methoxyphenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C18H23N3O3S
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0470992
|
1-(tert-Butylamino)-4-(2,2-dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)butan-2-ol
Show/Hide
|
C20H27N3O3S
|
1
|
| 1 |
IC50 = 853 nM
|
|
|
|
CP0845947
|
1-[1-(3-Methoxyphenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C19H32Cl2N2O2
|
2
|
| 1 |
IC50 = 870 nM
|
|
|
| 2 |
Ki = 745 nM
|
|
|
|
CP0514771
|
3-[1-(4-chlorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C17H20ClN3O2S
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
|
CP0417786
|
3-(phenylsulfonyl)-1H-indole, 18m
Show/Hide
|
C16H16N2O2S
|
2
|
| 1 |
IC50 = 960 nM
|
|
|
| 2 |
Ki = 792 nM
|
|
|
|
CP0514772
|
3-[1-(3,4-difluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C17H19F2N3O2S
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0390204
|
N-methyl-3-[1-(3-methylphenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]propan-1-amine
Show/Hide
|
C18H23N3O2S
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
|
CP0437723
|
(S)-4-fluoro-1-isopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C20H24FN3O
|
1
|
| 1 |
IC50 = 1053 nM
|
|
|
|
CP0439024
|
3-(phenylsulfonyl)-1H-indole, 18l
Show/Hide
|
C22H26N2O2S
|
2
|
| 1 |
IC50 = 1092 nM
|
|
|
| 2 |
Ki = 1130 nM
|
|
|
|
CP0475059
|
(R,R/S,S)-anti-1-(methyl(phenyl)amino)-3-(methylamino)-1-phenylpropan-2-ol
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0439256
|
(+/-)-Erythro--3-(ethylamino)-1-(3-methyl-1H-indol-1-yl)-1-phenylpropan-2-ol
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0418156
|
(+/-)-Erythro--3-(ethylamino)-1-(1H-indol-1-yl)-1-phenylpropan-2-ol
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0845953
|
(-)-1-{(1R)-2-Piperazin-1-yl-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrochloride
Show/Hide
|
C19H29Cl2F3N2O2
|
2
|
| 1 |
IC50 = 1290 nM
|
|
|
| 2 |
Ki = 544 nM
|
|
|
|
CP0390214
|
2-[6-fluoro-1-(2-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylethanamine
Show/Hide
|
C16H17F2N3O2S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0911666
|
1-[1-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
Show/Hide
|
C19H31Cl2FN2O
|
2
|
| 1 |
IC50 = 1452 nM
|
|
|
| 2 |
Ki = 1376 nM
|
|
|
|
CP0850317
|
1-[1-(4-Fluorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C18H29Cl2FN2O
|
2
|
| 1 |
IC50 = 1499 nM
|
|
|
| 2 |
Ki = 1034 nM
|
|
|
|
CP0520513
|
3-[1-(3-chloro-4-fluorophenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C17H19ClFN3O2S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0523831
|
4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H)-yl)-1-(isopropylamino)butan-2-ol
Show/Hide
|
C19H25N3O3S
|
1
|
| 1 |
IC50 = 2255 nM
|
|
|
|
CP0375854
|
1-[(4-methylmorpholin-2-yl)methyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide
Show/Hide
|
C18H21N3O3S
|
2
|
| 1 |
IC50 = 2304 nM
|
|
|
| 2 |
IC50 = 4310 nM
|
|
|
|
CP0845946
|
(+)-1-{(1R)-2-(4-Methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride
Show/Hide
|
C20H31Cl2F3N2O2
|
2
|
| 1 |
IC50 = 3474 nM
|
|
|
| 2 |
Ki = 785 nM
|
|
|
|
CP0520512
|
3-[1-(4-methoxyphenyl)-2,2-dioxo-4H-2lambda6,1,3-benzothiadiazin-3-yl]-N-methylpropan-1-amine
Show/Hide
|
C18H23N3O3S
|
1
|
| 1 |
IC50 = 3550 nM
|
|
|
|
CP0386422
|
(-)-R-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpiperazin-1-yl)ethyl)cyclohexanol
Show/Hide
|
C17H27ClN2OS
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0406081
|
3-[(1S,2R)-3-(Ethylamino)-2-hydroxy-1-phenylpropyl]-5-fluoro-1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one
Show/Hide
|
C21H26FN3O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0845951
|
1-[1-(4-Methoxyphenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C19H32Cl2N2O2
|
1
|
| 1 |
Ki = 519 nM
|
|
|
|
CP0852054
|
1-[1-(4-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride
Show/Hide
|
C18H29Cl3N2O
|
1
|
| 1 |
Ki = 717 nM
|
|
|
|
CP0852055
|
1-[1-(4-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride
Show/Hide
|
C19H31Cl3N2O
|
1
|
| 1 |
Ki = 1220 nM
|
|
|
