General Information of the Cell Line
Cell Line ID
CL000928
Cell Line Name
293GT
Category
Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Tissue Information
Kidney
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01141, Focal adhesion kinase 1
Compound ID Compound Name Compound Formula
CP0016998
2-[4-[4-[[5-chloro-7-[2-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C27H30ClN7O3S
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0392582
2-[4-[4-[[7-[2-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C27H31N7O3S
 1
1
IC50 = 610 nM
   TI
   LI
   LO
   TS
CP0474017
2-[4-[4-[[7-[3-(methanesulfonamido)phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C26H29N7O3S
 1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0387525
2-[4-[4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C26H28N6O2
 1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
CP0391780
2-[4-[4-[[7-[2-[methyl(methylsulfonyl)amino]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C26H30N8O3S
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0456832
2-[4-[4-[[7-(3-methylsulfonylphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C26H28N6O3S
 1
1
IC50 = 1010 nM
   TI
   LI
   LO
   TS
CP0509092
2-[4-[4-[[7-(6-methoxypyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C25H27N7O2
 1
1
IC50 = 1190 nM
   TI
   LI
   LO
   TS
CP0392584
2-[4-[4-[[5-methyl-7-[2-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C28H33N7O3S
 1
1
IC50 = 1230 nM
   TI
   LI
   LO
   TS
CP0489047
2-[4-[4-[[7-[3-(tert-butylsulfamoyl)phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C29H35N7O3S
 1
1
IC50 = 1340 nM
   TI
   LI
   LO
   TS
CP0392583
2-[4-[4-[[7-[3-(hydroxymethyl)phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C26H28N6O2
 1
1
IC50 = 1390 nM
   TI
   LI
   LO
   TS
CP0390801
2-[4-[4-[[7-(4-methylsulfonylphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C26H28N6O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0454945
2-[4-[4-[[7-(3-methoxypyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C25H27N7O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0454946
2-[4-[4-[[7-[3-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
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C27H31N7O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Kidney)
Cell Line Name Organism Disease
G-402 Homo sapiens (Human) Kidney neoplasm
A-498 Homo sapiens (Human) Renal cell carcinoma
786-O Homo sapiens (Human) Renal cell carcinoma
SN12C Homo sapiens (Human) Renal cell carcinoma
G-401 Homo sapiens (Human) Rhabdoid tumor of the kidney
AU-BEK Bos taurus (Bovine) -
MDCK Canis lupus familiaris (Dog) -
MDCK-II Canis lupus familiaris (Dog) -
MDCK-I Canis lupus familiaris (Dog) -
MDCK-MDR1 Canis lupus familiaris (Dog) -
MDCKII-LE Canis lupus familiaris (Dog) -
DK Canis lupus familiaris (Dog) -
MDCK2/BCRP Canis lupus familiaris (Dog) -
MDCK-Net6 Canis lupus familiaris (Dog) -
MDCK-UT-A1-AQP1-YFP Canis lupus familiaris (Dog) -
CV-1 Chlorocebus aethiops (Green monkey) -
COS-7 Chlorocebus aethiops (Green monkey) -
COS-1 Chlorocebus aethiops (Green monkey) -
COS-M6 Chlorocebus aethiops (Green monkey) -
COS Chlorocebus aethiops (Green monkey) -
OAT1-COS7 Chlorocebus aethiops (Green monkey) -
BS-C-1 Chlorocebus pygerythrus (Vervet monkey) -
Vero Chlorocebus sabaeus (Green monkey) -
OK Didelphis virginiana (North American opossum) -
HEK293 Homo sapiens (Human) -
HEK-293T Homo sapiens (Human) -
tsA201 Homo sapiens (Human) -
HEK293-A Homo sapiens (Human) -
T-REx-293 Homo sapiens (Human) -
HEK293-EBNA Homo sapiens (Human) -
Expi293F Homo sapiens (Human) -
Flp-In-293 Homo sapiens (Human) -
HEK293S Homo sapiens (Human) -
HEK293-F Homo sapiens (Human) -
HEK293-EBNA1-6E Homo sapiens (Human) -
AD-293 Homo sapiens (Human) -
HEK293-H Homo sapiens (Human) -
HEK-Blue hNOD2 Homo sapiens (Human) -
HEK293T/17 Homo sapiens (Human) -
293T/ACE2 [Japan 2021] Homo sapiens (Human) -
GripTite 293 MSR Homo sapiens (Human) -
HL-2 Homo sapiens (Human) -
HEK-Blue hTLR8 Homo sapiens (Human) -
PathHunter HEK 293 EDG1 Total GPCR Internalization Homo sapiens (Human) -
Flp-In-T-REx-293 Homo sapiens (Human) -
HEKR2 Homo sapiens (Human) -
HEK-Blue IL-6 Homo sapiens (Human) -
HK-2 [Human kidney] Homo sapiens (Human) -
HEK293-FT Homo sapiens (Human) -
HEK-2 Homo sapiens (Human) -
HEK-Blue hTLR2 Homo sapiens (Human) -
HEK-Blue hTLR4 Homo sapiens (Human) -
HEK-Blue CD40L Homo sapiens (Human) -
Expi293F GnTI- Homo sapiens (Human) -
HEK-Blue hNOD1 Homo sapiens (Human) -
pEAK Rapid Homo sapiens (Human) -
HEK-Blue hTLR9 Homo sapiens (Human) -
HEK-Blue hTLR7 Homo sapiens (Human) -
293Ta Homo sapiens (Human) -
293-Dual hSTING-R232 Homo sapiens (Human) -
HEK293-CNG Homo sapiens (Human) -
FreeStyle 293-F Homo sapiens (Human) -
PrecisION hnAChR alpha7/ric3-HEK Homo sapiens (Human) -
GeneBLAzer ERbeta-UAS-bla GripTite 293 Homo sapiens (Human) -
HEK385-7 Homo sapiens (Human) -
HEK2935 Homo sapiens (Human) -
ACTOne CXCR4 Homo sapiens (Human) -
HEK298 Homo sapiens (Human) -
HEK273 Homo sapiens (Human) -
293/GFP Homo sapiens (Human) -
HEK293 AequoScreen Homo sapiens (Human) -
HEK-Blue Null1-v Homo sapiens (Human) -
HEK-GIRK-M4 Homo sapiens (Human) -
HTLA Homo sapiens (Human) -
HEK293/Galpha15 Homo sapiens (Human) -
HEK293-SF-hH4R-His6-CRE-Luc Homo sapiens (Human) -
HEK293-SF-mH4R-His6-CRE-Luc Homo sapiens (Human) -
293AD Homo sapiens (Human) -
HEK293T/Galpha16-gustducin 44 Homo sapiens (Human) -
CellSensor SBE-bla HEK 293T Homo sapiens (Human) -
NRK1-HEK293T Homo sapiens (Human) -
HEK293T-SF-His6-CRE-Luc Homo sapiens (Human) -
HEK293T-beta-arr2-rH4R Homo sapiens (Human) -
HEK293T-beta-arr2-mH4R Homo sapiens (Human) -
HEK293T-beta-arr2-hH4R Homo sapiens (Human) -
HEK293T-SP-FLAG-hH3R-CRE-CBR Homo sapiens (Human) -
293/AP1-luc Homo sapiens (Human) -
GeneBLAzer AR-UAS-bla Griptite 293 Homo sapiens (Human) -
UAS-MR-bla HEK293 Homo sapiens (Human) -
HEK293-DR-GFP Homo sapiens (Human) -
PSC-HEK293 Homo sapiens (Human) -
HEK-293-A2B Homo sapiens (Human) -
HEK293-SF-rH4R-His6-CRE-Luc Homo sapiens (Human) -
Hana3A Homo sapiens (Human) -
HEK293S GnTI- Homo sapiens (Human) -
GeneBLAzer UAS-bla GripTite 293 Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293H Homo sapiens (Human) -
GeneBLAzer UAS-bla HEK 293T Homo sapiens (Human) -
HEKMSR2 Homo sapiens (Human) -
HEK-hNET Homo sapiens (Human) -
HEK-hDAT Homo sapiens (Human) -
HEK-hSERT Homo sapiens (Human) -
EE-HEK293 Homo sapiens (Human) -
HEK-A2A Homo sapiens (Human) -
HEK293EM Homo sapiens (Human) -
293-NB2 Homo sapiens (Human) -
HEK-SEAP Homo sapiens (Human) -
HEK293/Gal4 Homo sapiens (Human) -
Octn2-HEK Homo sapiens (Human) -
Octn1-HEK Homo sapiens (Human) -
Octn3-HEK Homo sapiens (Human) -
HEK293superTOP Homo sapiens (Human) -
HEK293T-ARRB1 Homo sapiens (Human) -
HEK293T-ARRB2 Homo sapiens (Human) -
HEK293T-qs5-HA Homo sapiens (Human) -
EDG3-Ga15-bla HEK293T Homo sapiens (Human) -
LLC-MK2 Macaca mulatta (Rhesus macaque) -
BHK-21 Mesocricetus auratus (Golden hamster) -
BHK-21 clone 13 Mesocricetus auratus (Golden hamster) -
BHK570 Mesocricetus auratus (Golden hamster) -
TK-TS 13 Mesocricetus auratus (Golden hamster) -
BHK/AC9 Mesocricetus auratus (Golden hamster) -
mIMCD-3 Mus musculus (Mouse) -
RK3E Rattus norvegicus (Rat) -
KNRK Rattus norvegicus (Rat) -
NRK-52E Rattus norvegicus (Rat) -
SKPT-0193 Cl.2 Rattus norvegicus (Rat) -
RKE Rattus norvegicus (Rat) -
LLC-PK1 Sus scrofa (Pig) -
LLC-GA5-CoL150 Sus scrofa (Pig) -
PK-15 Sus scrofa (Pig) -
HKRK-B28 Sus scrofa (Pig) -
PK15NTD Sus scrofa (Pig) -