| Compound ID |
Compound Name |
Compound Formula |
|
CP0001861
|
6-[N-Ethyl(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthyl)amino]nicotinic acid
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|
C22H28N2O2
|
2
|
| 1 |
EC50 = 3.8 nM
|
|
|
| 2 |
EC50 = 5.3 nM
|
|
|
|
CP0488232
|
6-[N-ethyl-3-(3-fluoro-2-methylpropoxy)-4-propan-2-ylanilino]pyridine-3-carboxylic acid
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|
C21H27FN2O3
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0019002
|
1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)-2-(trifluoromethyl)benzimidazole-5-carboxylic acid
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|
C24H25F3N2O2
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0005162
|
6-[Ethyl-(3-isobutoxy-4-isopropylphenyl)amino]nicotinic acid
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|
C21H28N2O3
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0004259
|
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
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|
C24H28O2
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0430013
|
3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)-2-(trifluoromethyl)imidazo[4,5-b]pyridine-6-carboxylic acid
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|
C23H24F3N3O2
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0044243
|
6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID
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|
C24H29NO2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0395900
|
6-[Ethyl-(3-isopropoxy-4-isopropylphenyl)amino]nicotinic acid
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|
C20H26N2O3
|
1
|
| 1 |
EC50 = 66 nM
|
|
|
|
CP0391820
|
1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)indole-5-carboxylic acid
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|
C24H27NO2
|
1
|
| 1 |
EC50 = 83 nM
|
|
|
|
CP0474417
|
6-{Ethyl-[4-isopropyl-3-(2-methylallyloxy)phenyl]amino}nicotinic acid
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|
C21H26N2O3
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0005411
|
1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid
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|
C22H25N3O2
|
1
|
| 1 |
EC50 = 143 nM
|
|
|
|
CP0386201
|
2-amino-1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzimidazole-5-carboxylic acid
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|
C23H27N3O2
|
1
|
| 1 |
EC50 = 155 nM
|
|
|
|
CP0002059
|
6-[(3-Benzyloxy-4-isopropylphenyl)-ethylamino]nicotinic acid
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|
C24H26N2O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0011145
|
6-[Ethyl-(4-isopropyl-3-pentyloxyphenyl)amino]nicotinic acid
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|
C22H30N2O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0441346
|
6-{Ethyl-[4-isopropyl-3-(2,2,2-trifluoroethoxy)phenyl]amino}nicotinic acid
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|
C19H21F3N2O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0512559
|
6-{Ethyl-[4-isopropyl-3-(3-methyl-but-2-enyloxy)phenyl]amino}nicotinic acid
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|
C22H28N2O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0553431
|
6-[N-ethyl-4-(2-methylpropoxy)-3-propan-2-ylanilino]pyridine-3-carboxylic acid
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|
C21H28N2O3
|
1
|
| 1 |
EC50 = 169 nM
|
|
|
|
CP0437186
|
6-[(3-Butoxy-4-isopropylphenyl)-ethylamino]nicotinic acid
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|
C21H28N2O3
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0430012
|
3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)triazolo[4,5-b]pyridine-6-carboxylic acid
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|
C21H24N4O2
|
1
|
| 1 |
EC50 = 275 nM
|
|
|
|
CP0437187
|
6-[Ethyl-(3-hexyloxy-4-isopropylphenyl)amino]nicotinic acid
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|
C23H32N2O3
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0009895
|
6-[(3-Cyclopropylmethoxy-4-isopropylphenyl)-ethylamino]nicotinic acid
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|
C21H26N2O3
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0516602
|
6-[Ethyl-(4-isopropyl-3-phenethyloxyphenyl)amino]nicotinic acid
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|
C25H28N2O3
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0005964
|
2-methyl-1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzimidazole-5-carboxylic acid
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|
C24H28N2O2
|
1
|
| 1 |
EC50 = 367 nM
|
|
|
|
CP0474418
|
6-[Ethyl-(4-isopropyl-3-propoxyphenyl)amino]nicotinic acid
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|
C20H26N2O3
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0400650
|
6-[N-ethyl-4-(3-fluoro-2-methylpropoxy)-3-propan-2-ylanilino]pyridine-3-carboxylic acid
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|
C21H27FN2O3
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0387139
|
1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzimidazole-5-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 633 nM
|
|
|
|
CP0465701
|
6-{Ethyl-[4-isopropyl-3-(3-phenylpropoxy)phenyl]amino}nicotinic acid
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|
C26H30N2O3
|
1
|
| 1 |
EC50 = 820 nM
|
|
|
|
CP0185678
|
3-amino-6-(3-aminopropyl)indeno[1,2-c]isoquinoline-5,11-dione
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|
C19H17N3O2
|
2
|
| 1 |
EC50 = 3370 nM
|
|
|
| 2 |
EC50 = 4400 nM
|
|
|
|
CP0262862
|
6-(3-aminopropyl)-3-(methylamino)indeno[1,2-c]isoquinoline-5,11-dione
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|
C20H19N3O2
|
2
|
| 1 |
EC50 = 4220 nM
|
|
|
| 2 |
EC50 = 7650 nM
|
|
|
|
CP0410846
|
6-(3-aminopropyl)-9-methoxyindeno[1,2-c]isoquinoline-5,11-dione
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|
C20H18N2O3
|
1
|
| 1 |
EC50 = 4840 nM
|
|
|
|
CP0169413
|
3-amino-6-[3-(dimethylamino)propyl]indeno[1,2-c]isoquinoline-5,11-dione
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|
C21H21N3O2
|
1
|
| 1 |
EC50 = 7000 nM
|
|
|
|
CP0092337
|
2-[[6-(3-aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]acetic acid
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|
C21H19N3O4
|
1
|
| 1 |
EC50 = 8400 nM
|
|
|
|
CP0156291
|
6-(3-aminopropyl)indeno[1,2-c]isoquinoline-5,11-dione
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|
C19H16N2O2
|
1
|
| 1 |
EC50 = 8660 nM
|
|
|
|
CP0278348
|
6-[3-(methylamino)propyl]indeno[1,2-c]isoquinoline-5,11-dione
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|
C20H18N2O2
|
1
|
| 1 |
EC50 = 9220 nM
|
|
|
|
CP0271952
|
6-[3-(dimethylamino)propyl]indeno[1,2-c]isoquinoline-5,11-dione
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|
C21H20N2O2
|
1
|
| 1 |
EC50 = 9600 nM
|
|
|
|
CP0185935
|
3-amino-6-[3-(methylamino)propyl]indeno[1,2-c]isoquinoline-5,11-dione
Show/Hide
|
C20H19N3O2
|
2
|
| 1 |
EC50 = 9960 nM
|
|
|
| 2 |
EC50 = 15200 nM
|
|
|
|
CP0801261
|
3-amino-6-(3-aminopropyl)-6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one Hydrochloride
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|
C19H20ClN3O
|
1
|
| 1 |
EC50 = 10010 nM
|
|
|
|
CP0452469
|
3-bromo-6-[3-(methylamino)propyl]indeno[1,2-c]isoquinoline-5,11-dione
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|
C20H17BrN2O2
|
1
|
| 1 |
EC50 = 10720 nM
|
|
|
|
CP0130870
|
6-(4-aminobutyl)indeno[1,2-c]isoquinoline-5,11-dione
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|
C20H18N2O2
|
1
|
| 1 |
EC50 = 11300 nM
|
|
|
|
CP0188345
|
6-(5-aminopentyl)indeno[1,2-c]isoquinoline-5,11-dione
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|
C21H20N2O2
|
1
|
| 1 |
EC50 = 12200 nM
|
|
|
|
CP0391829
|
6-(2-aminoethyl)indeno[1,2-c]isoquinoline-5,11-dione
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|
C18H14N2O2
|
1
|
| 1 |
EC50 = 15900 nM
|
|
|
|
CP0130868
|
6-(6-aminohexyl)indeno[1,2-c]isoquinoline-5,11-dione
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|
C22H22N2O2
|
1
|
| 1 |
EC50 = 16400 nM
|
|
|
|
CP0452470
|
3-bromo-6-[3-(dimethylamino)propyl]indeno[1,2-c]isoquinoline-5,11-dione
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|
C21H19BrN2O2
|
1
|
| 1 |
EC50 = 18440 nM
|
|
|
|
CP0868015
|
methyl 6-(3-(dimethylamino)propyl)-5,11-dioxo-6,11-dihydro-5H-indeno[1,2-c]isoquinoline-3-carboxylate Hydrochloride
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|
C23H23ClN2O4
|
1
|
| 1 |
EC50 = 19460 nM
|
|
|
|
CP0185681
|
6-[3-(dimethylamino)propyl]-5,11-dioxoindeno[1,2-c]isoquinoline-3-carbonitrile
Show/Hide
|
C22H19N3O2
|
1
|
| 1 |
EC50 > 20700 nM
|
|
|
|
CP0397535
|
N-[3-(3-amino-5,11-dioxoindeno[1,2-c]isoquinolin-6-yl)propyl]acetamide
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|
C21H19N3O3
|
1
|
| 1 |
EC50 = 20910 nM
|
|
|
|
CP0185679
|
N-[6-(3-aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]acetamide
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|
C21H19N3O3
|
2
|
| 1 |
EC50 > 34700 nM
|
|
|
| 2 |
EC50 > 41400 nM
|
|
|
|
CP0156108
|
methyl 3-[[6-(3-aminopropyl)-5,11-dioxoindeno[1,2-c]isoquinolin-3-yl]amino]-3-oxopropanoate
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|
C23H21N3O5
|
1
|
| 1 |
EC50 > 44500 nM
|
|
|
|
CP0402291
|
(Z)-4-(5,7,7,10,10-pentamethyl-2-nitro-7,8,9,10-tetrahydro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid
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|
C29H29N3O4
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0485149
|
6-(4-methoxy-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
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|
C27H30N2O5S
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0401360
|
6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-4-(trifluoromethyl)phenylsulfonamido)nicotinic acid
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|
C27H27F3N2O4S
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0418571
|
6-(4-chloro-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
Show/Hide
|
C26H27ClN2O4S
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0435281
|
6-(4-methyl-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
Show/Hide
|
C27H30N2O4S
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0467403
|
6-(4-nitro-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
Show/Hide
|
C26H27N3O6S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485150
|
6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
Show/Hide
|
C26H28N2O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0509023
|
6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)butylsulfonamido)nicotinic acid
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|
C24H32N2O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0559200
|
1-(3-hexoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-2-(trifluoromethyl)benzimidazole-5-carboxylic acid
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|
C29H35F3N2O3
|
4
|
| 1 |
Kd = 6.761 nM
|
|
|
| 2 |
Kd = 125.89 nM
|
|
|
| 3 |
Kd = 281 nM
|
|
|
| 4 |
Ki = 391 nM
|
|
|
|
CP0565854
|
1-(5,5,8,8-tetramethyl-3-pentoxy-6,7-dihydronaphthalen-2-yl)-2-(trifluoromethyl)benzimidazole-5-carboxylic acid
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|
C28H33F3N2O3
|
4
|
| 1 |
Kd = 8.71 nM
|
|
|
| 2 |
Kd = 26.3 nM
|
|
|
| 3 |
Kd = 277 nM
|
|
|
| 4 |
Ki = 384 nM
|
|
|
|
CP0003993
|
1-[3-(2-ethoxyethoxy)-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl]-2-(trifluoromethyl)benzimidazole-5-carboxylic acid
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|
C27H31F3N2O4
|
1
|
| 1 |
Kd = 87.1 nM
|
|
|
|
CP0549890
|
1-(3-hexoxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid
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|
C27H35N3O3
|
2
|
| 1 |
Kd = 705 nM
|
|
|
| 2 |
Ki = 3157 nM
|
|
|
|
CP0549891
|
1-(5,5,8,8-tetramethyl-3-pentoxy-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid
Show/Hide
|
C26H33N3O3
|
2
|
| 1 |
Kd = 764 nM
|
|
|
| 2 |
Ki = 3541 nM
|
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|
