Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01474 , Retinoic acid receptor RXR-beta
 Protein Info 
Gene Name RXRB
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P28702
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109
 Cell Line Info 
 Protein ID: PT01474
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0402291
 Compound Info 
(Z)-4-(5,7,7,10,10-pentamethyl-2-nitro-7,8,9,10-tetrahydro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid
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C29H29N3O4
  1
1
IC50 = 44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0401360
 Compound Info 
6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-4-(trifluoromethyl)phenylsulfonamido)nicotinic acid
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C27H27F3N2O4S
  1
1
IC50 = 750 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418571
 Compound Info 
6-(4-chloro-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
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C26H27ClN2O4S
  1
1
IC50 = 870 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0435281
 Compound Info 
6-(4-methyl-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
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C27H30N2O4S
  1
1
IC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0485149
 Compound Info 
6-(4-methoxy-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
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C27H30N2O5S
  1
1
IC50 = 3900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0467403
 Compound Info 
6-(4-nitro-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
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C26H27N3O6S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0485150
 Compound Info 
6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenylsulfonamido)nicotinic acid
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C26H28N2O4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0509023
 Compound Info 
6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)butylsulfonamido)nicotinic acid
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C24H32N2O4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS