Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01329 , Alkaline phosphatase, tissue-nonspecific isozyme
 Protein Info 
Gene Name ALPL
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P05186
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109
 Cell Line Info 
 Protein ID: PT01329
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0148215
 Compound Info 
5-Bromo-2-methoxy-N-(quinolin-3-yl)benzenesulfonamide
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C16H13BrN2O3S
  1
1
IC50 = 120 nM
 Bioactivity Info 
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CP0083678
 Compound Info 
2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide
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C17H16N2O4S
  1
1
IC50 = 190 nM
 Bioactivity Info 
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CP0356953
 Compound Info 
5-chloro-2-methoxy-4-methyl-N-(pyridin-3-yl)benzenesulfonamide
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C13H13ClN2O3S
  1
1
IC50 = 510 nM
 Bioactivity Info 
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CP0143519
 Compound Info 
5-chloro-2-ethoxy-N-(pyridin-3-yl)benzenesulfonamide
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C13H13ClN2O3S
  1
1
IC50 = 540 nM
 Bioactivity Info 
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CP0140027
 Compound Info 
2-Methoxy-5-methyl-N-(quinolin-3-yl)benzenesulfonamide
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C17H16N2O3S
  1
1
IC50 = 650 nM
 Bioactivity Info 
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CP0106688
 Compound Info 
5-chloro-2-ethoxy-4-methyl-N-(pyridin-3-yl)benzenesulfonamide
   Show/Hide
C14H15ClN2O3S
  1
1
IC50 = 690 nM
 Bioactivity Info 
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CP0506495
 Compound Info 
2-Methoxy-4-nitro-N-(quinolin-3-yl)benzenesulfonamide
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C16H13N3O5S
  1
1
IC50 = 740 nM
 Bioactivity Info 
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CP0141637
 Compound Info 
2,5-Dimethoxy-N-(pyridin-3-yl)benzenesulfonamide
   Show/Hide
C13H14N2O4S
  1
1
IC50 = 1060 nM
 Bioactivity Info 
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CP0143488
 Compound Info 
4-chloro-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulfonamide
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C13H13ClN2O4S
  1
1
IC50 = 1130 nM
 Bioactivity Info 
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CP0346479
 Compound Info 
2-ethoxy-5-methyl-N-(pyridin-3-yl)benzenesulfonamide
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C14H16N2O3S
  1
1
IC50 = 1130 nM
 Bioactivity Info 
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CP0204569
 Compound Info 
5-fluoro-2-methoxy-N-(pyridin-3-yl)benzenesulfonamide
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C12H11FN2O3S
  1
1
IC50 = 1290 nM
 Bioactivity Info 
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CP0164824
 Compound Info 
2,5-dimethoxy-4-methyl-N-(pyridin-3-yl)benzenesulfonamide
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C14H16N2O4S
  1
1
IC50 = 1490 nM
 Bioactivity Info 
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CP0343490
 Compound Info 
4-bromo-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulfonamide
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C13H13BrN2O4S
  1
1
IC50 = 1550 nM
 Bioactivity Info 
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CP0330142
 Compound Info 
2-methoxy-4,5-dimethyl-N-(pyridin-3-yl)benzenesulfonamide
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C14H16N2O3S
  1
1
IC50 = 1680 nM
 Bioactivity Info 
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CP0108113
 Compound Info 
2-Methoxy-5-methyl-N-(pyridin-3-yl)benzenesulfonamide
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C13H14N2O3S
  1
1
IC50 = 1850 nM
 Bioactivity Info 
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CP0054936
 Compound Info 
2-Methoxy-4-nitro-N-(pyridin-3-yl)benzenesulfonamide
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C12H11N3O5S
  1
1
IC50 = 3160 nM
 Bioactivity Info 
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CP0042864
 Compound Info 
3-Methoxy-N-(quinolin-3-yl)benzenesulfonamide
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C16H14N2O3S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0042959
 Compound Info 
2,5-Dimethoxy-N-(quinolin-6-yl)benzenesulfonamide
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C17H16N2O4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0042982
 Compound Info 
N-[(2,5-dimethoxyphenyl)methyl]quinolin-3-amine
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C18H18N2O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0071697
 Compound Info 
N-(2,5-dimethoxyphenyl)quinoline-3-sulfonamide
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C17H16N2O4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0202120
 Compound Info 
5-Chloro-2-methoxy-N-(quinolin-3-yl)benzenesulfonamide
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C16H13FN2O3S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0288540
 Compound Info 
2,5-Dimethoxy-N-(naphthalen-2-yl)benzenesulfonamide
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C18H17NO4S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0221680
 Compound Info 
N-(2,5-dimethylphenyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
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C17H17N3O5S
  1
1
IC50 = 35000 nM
 Bioactivity Info 
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CP0379757
 Compound Info 
N-(3,4-dimethoxyphenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C18H19N3O7S
  1
1
IC50 = 37000 nM
 Bioactivity Info 
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CP0420783
 Compound Info 
N-[(3-methoxyphenyl)methyl]-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
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C17H17N3O6S
  1
1
IC50 = 74000 nM
 Bioactivity Info 
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CP0458648
 Compound Info 
N-(4-cyanophenyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
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C16H12N4O5S
  1
1
IC50 = 81000 nM
 Bioactivity Info 
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CP0433087
 Compound Info 
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
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C21H25N3O7S
  1
1
IC50 = 96000 nM
 Bioactivity Info 
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CP0379748
 Compound Info 
1-[2-(1,3-benzodioxol-5-yl)ethyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
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C17H15N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379750
 Compound Info 
N-[(2-chlorophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C17H16ClN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379753
 Compound Info 
3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N-[[3-(trifluoromethyl)phenyl]methyl]propanamide
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C18H16F3N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379756
 Compound Info 
N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C19H19N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379758
 Compound Info 
N-[(4-chlorophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C17H16ClN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379759
 Compound Info 
N-(2,5-dimethylphenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C18H19N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379761
 Compound Info 
1-[(4-methoxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
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C16H15N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379784
 Compound Info 
N-[(3-fluorophenyl)methyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
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C18H18FN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379785
 Compound Info 
N-(3,4-dimethylphenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C18H19N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379919
 Compound Info 
N-benzyl-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C17H17N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0379922
 Compound Info 
N-(1,3-benzodioxol-5-ylmethyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
   Show/Hide
C17H15N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0420780
 Compound Info 
N-[(4-methylphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C18H19N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0420781
 Compound Info 
N-(2,5-dimethylphenyl)-3-[(3-methyl-2-oxo-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C19H21N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0420782
 Compound Info 
N-(1,3-benzodioxol-5-ylmethyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C18H17N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0431421
 Compound Info 
N-[(2-methylphenyl)methyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
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C19H21N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0431422
 Compound Info 
3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N-o-anisyl-propionamide
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C18H19N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0431749
 Compound Info 
N-[2-(4-methoxyphenyl)ethyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C20H23N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0431754
 Compound Info 
N-[(3-cyanophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C18H16N4O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433080
 Compound Info 
N-(2,4-dimethoxyphenyl)-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C19H21N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433081
 Compound Info 
N-[2-(4-hydroxyphenyl)ethyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C19H21N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433082
 Compound Info 
N-[(3-chlorophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C17H16ClN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433083
 Compound Info 
N-[3-(1,3-benzodioxol-5-yl)propyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C20H21N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433084
 Compound Info 
N-[(3-fluorophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C17H16FN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433085
 Compound Info 
N-[2-(1,3-benzodioxol-5-yl)ethyl]-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
   Show/Hide
C18H17N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0433086
 Compound Info 
N-[(4-methoxyphenyl)methyl]-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
   Show/Hide
C17H17N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0443495
 Compound Info 
N-(2-fluorophenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C16H14FN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0444274
 Compound Info 
N-(3,4-dimethoxyphenyl)-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C19H21N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0444293
 Compound Info 
N-(2-chlorophenyl)-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C17H16ClN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0444294
 Compound Info 
N-(1,3-benzodioxol-5-yl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C17H15N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0444295
 Compound Info 
1-(1,3-benzodioxol-5-yl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
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C15H11N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0446941
 Compound Info 
3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
   Show/Hide
C18H16F3N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0447232
 Compound Info 
N-[(4-hydroxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C17H17N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0456652
 Compound Info 
N-(1,3-benzodioxol-5-ylmethyl)-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C19H19N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0457355
 Compound Info 
N-[(2,4-dimethoxyphenyl)methyl]-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
   Show/Hide
C18H19N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0457379
 Compound Info 
N-[(3,4-dihydroxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C17H17N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0457380
 Compound Info 
1-(3-cyanophenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
   Show/Hide
C15H10N4O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0457381
 Compound Info 
N-[(2,4-dimethoxyphenyl)methyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
   Show/Hide
C20H23N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0457382
 Compound Info 
N-[(4-fluorophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C17H16FN3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0457383
 Compound Info 
N-[(4-methoxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
   Show/Hide
C18H19N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0458646
 Compound Info 
1-(4-cyanophenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
   Show/Hide
C15H10N4O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0458650
 Compound Info 
1-(2,5-dimethylphenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
   Show/Hide
C16H15N3O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0460353
 Compound Info 
3-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonylamino]-N-m-anisyl-propionamide
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C18H19N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0460354
 Compound Info 
1-(3,4-dimethoxyphenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
   Show/Hide
C16H15N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0460355
 Compound Info 
N-(3-cyanophenyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
   Show/Hide
C16H12N4O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0461277
 Compound Info 
1-[(2,4-dimethoxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
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C17H17N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0467288
 Compound Info 
N-(3-cyanophenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C17H14N4O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0481235
 Compound Info 
N-[(3,4-dimethoxyphenyl)methyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
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C20H23N3O7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0481236
 Compound Info 
1-[(3-methoxyphenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]urea
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C16H15N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
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CP0493898
 Compound Info 
N-[(2-methoxyphenyl)methyl]-4-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]butanamide
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C19H21N3O6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
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   TS