General Information of the Protein
Protein ID
PT03662
Protein Name
Intestinal-type alkaline phosphatase
Gene Name
ALPI
Sequence
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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Organism
Homo sapiens, Human
Protein Classification
Enzyme
>
Phosphatase
Function
Alkaline phosphatase that can hydrolyze various phosphate compounds.
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Uniprot ID
Primary ID:
P09923

Secondarily ID:
B2R7Y4
Q53S80
Q9UBV5
Q9UCL2
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Ensembl ID
ENSG00000163295
HGNC ID
HGNC:437
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0221680
 Compound Info 
N-(2,5-dimethylphenyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamide
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C17H17N3O5S
  1
1
IC50 = 27600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0467288
 Compound Info 
N-(3-cyanophenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamide
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C17H14N4O5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Biochemical Assays
Compound ID Compound Name Compound Formula
CP0036918
 Compound Info 
(2S)-2-amino-3-phenylpropanoic acid
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C9H11NO2
  1
1 IC50 > 5000 nM