Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT01091 , Fibroblast growth factor receptor 1
 Protein Info 
Gene Name FGFR1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P11362
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109
 Cell Line Info 
 Protein ID: PT01091
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0153243
 Compound Info 
4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
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C22H25N7O3
  1
1
IC50 < 15.85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383439
 Compound Info 
5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(2-phenylethyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine
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C20H20BrN7O
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383438
 Compound Info 
5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-propyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
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C15H18BrN7O
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383498
 Compound Info 
5-bromo-2-N-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
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C16H20BrN7O
  1
1
IC50 = 158.49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423870
 Compound Info 
5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
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C13H14BrN7O
  1
1
IC50 = 158.49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383500
 Compound Info 
5-bromo-4-N-[5-(3-methoxypropyl)-1H-pyrazol-3-yl]-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
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C16H20BrN7O2
  1
1
IC50 = 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383497
 Compound Info 
5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-(2-pyridin-3-ylethyl)pyrimidine-2,4-diamine
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C15H16BrN7
  1
1
IC50 = 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423869
 Compound Info 
5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-prop-2-enylpyrimidine-2,4-diamine
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C11H13BrN6
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS