Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-bromo-2-N-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
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 PubChem ID
CID: 60154286
SID: 144085209
Canonical SMILES
Cc1cc(Nc2nc(NCc3cc(no3)C(C)(C)C)ncc2Br)[nH]n1
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Compound Formula C16H20BrN7O
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 158.49 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 31.62 nM
   TI
   LI
   LO
   TS