Brief Information of the Cell Line and Protein
Cell Line ID: CL000192 , AD-293
 Cell Line Info 
Synonyms
Ad-293
AD293
Adeno-293
Adeno 293
HEK-AD293
HEK (AD293)
HEK AD293
HEK-AD 293
AdHek
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_9804
Protein ID: PT00681 , Phosphodiesterase
 Protein Info 
Gene Name PDE2A3
Organism Macaca mulatta, Rhesus macaque
Protein Classification Enzyme
Uniprot ID B3VTJ2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000192
 Cell Line Info 
 Protein ID: PT00681
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0468287
 Compound Info 
2-(dimethylamino)-N-[(1R)-2-methyl-1-[4-(trifluoromethylsulfanyl)phenyl]propyl]-6-oxo-1H-pyrimidine-4-carboxamide
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C18H21F3N4O2S
  1
1
Ki = 0.19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0512495
 Compound Info 
2-(dimethylamino)-6-oxo-N-[(1R)-1-[4-(trifluoromethylsulfanyl)phenyl]propyl]-1H-pyrimidine-4-carboxamide
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C17H19F3N4O2S
  1
1
Ki = 0.51 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565494
 Compound Info 
2-(dimethylamino)-6-oxo-N-[(1R)-1-[4-(trifluoromethylsulfanyl)phenyl]ethyl]-1H-pyrimidine-4-carboxamide
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C16H17F3N4O2S
  1
1
Ki = 0.57 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0466631
 Compound Info 
2-(dimethylamino)-N-[1-[3-fluoro-4-(trifluoromethyl)phenyl]cyclopropyl]-6-oxo-1H-pyrimidine-4-carboxamide
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C17H16F4N4O2
  1
1
Ki = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0468288
 Compound Info 
N-[(1R)-1-[3-chloro-4-(trifluoromethoxy)phenyl]ethyl]-2-(dimethylamino)-6-oxo-1H-pyrimidine-4-carboxamide
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C16H16ClF3N4O3
  1
1
Ki = 0.82 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS