| Compound ID |
Compound Name |
Compound Formula |
|
CP0400720
|
US9200001, 13
Show/Hide
|
C27H25N7O2
|
1
|
| 1 |
Ki = 0.01 nM
|
|
|
|
CP0472525
|
US8785467, 1-27
Show/Hide
|
C21H23ClN6OS
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0521287
|
US9062059, 2-27
Show/Hide
|
C21H21N7OS
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0521535
|
US9200001, 2
Show/Hide
|
C28H24N6O2
|
1
|
| 1 |
Ki = 0.023 nM
|
|
|
|
CP0506743
|
US9200001, 16
Show/Hide
|
C27H27N7O2
|
1
|
| 1 |
Ki = 0.027 nM
|
|
|
|
CP0859111
|
US9200001, 25
Show/Hide
|
C27H27N7O2
|
1
|
| 1 |
Ki = 0.027 nM
|
|
|
|
CP0521536
|
US9200001, 8
Show/Hide
|
C27H27N7O2
|
1
|
| 1 |
Ki = 0.028 nM
|
|
|
|
CP0563887
|
US9062059, 1-2
Show/Hide
|
C19H22N6O
|
1
|
| 1 |
Ki = 0.03 nM
|
|
|
|
CP0452638
|
US8785467, 1-32
Show/Hide
|
C21H21ClN6O2S
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0488810
|
US9062059, 2-3
Show/Hide
|
C20H24N6O
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0475394
|
US8975261, I-42
Show/Hide
|
C24H20N6O
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0411005
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-2-(3-imidazo[1,2-a]pyridin-2-ylpropoxy)-5-methylpyrimidin-4-amine
Show/Hide
|
C21H23ClN6OS
|
1
|
| 1 |
Ki = 0.047 nM
|
|
|
|
CP0575642
|
US9062059, 2-53
Show/Hide
|
C18H21N7O2S
|
1
|
| 1 |
Ki = 0.05 nM
|
|
|
|
CP0384996
|
2-[3-(1,3-benzothiazol-2-yl)propoxy]-6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methylpyrimidin-4-amine
Show/Hide
|
C21H22ClN5OS2
|
1
|
| 1 |
Ki = 0.055 nM
|
|
|
|
CP0549907
|
US9200001, 15
Show/Hide
|
C26H26N8O2
|
1
|
| 1 |
Ki = 0.056 nM
|
|
|
|
CP0557971
|
US9200001, 34
Show/Hide
|
C28H27N7O2
|
1
|
| 1 |
Ki = 0.068 nM
|
|
|
|
CP0419269
|
US9200001, 7
Show/Hide
|
C27H23N7O2
|
1
|
| 1 |
Ki = 0.073 nM
|
|
|
|
CP0424181
|
US9062059, 9-2
Show/Hide
|
C21H24N6OS
|
1
|
| 1 |
Ki = 0.08 nM
|
|
|
|
CP0549912
|
US9200001, 61
Show/Hide
|
C20H18N8
|
1
|
| 1 |
Ki = 0.085 nM
|
|
|
|
CP0488812
|
US9062059, 3-25
Show/Hide
|
C20H22FN7OS
|
1
|
| 1 |
Ki = 0.09 nM
|
|
|
|
CP0548843
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methyl-2-[3-(1,8-naphthyridin-2-yl)propoxy]pyrimidin-4-amine
Show/Hide
|
C22H23ClN6OS
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0549908
|
US9200001, 20
Show/Hide
|
C25H26N6O2
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0429119
|
US9200001, 5
Show/Hide
|
C25H28N6O2
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0549910
|
US9200001, 50
Show/Hide
|
C17H20N6
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0517411
|
US8975261, I-31
Show/Hide
|
C21H25N3O3
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0549909
|
US9200001, 49
Show/Hide
|
C24H24N6
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0563314
|
US9200001, 35
Show/Hide
|
C26H28N6O2
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0542955
|
US8975261, I-36
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
Ki = 0.22 nM
|
|
|
|
CP0442232
|
US8975261, LL3
Show/Hide
|
C23H23N5O3
|
1
|
| 1 |
Ki = 0.23 nM
|
|
|
|
CP0475393
|
US8975261, MM4
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0532985
|
US8975261, I-39
Show/Hide
|
C22H24N4O2
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0541118
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methyl-2-(3-quinoxalin-2-ylpropoxy)pyrimidin-4-amine
Show/Hide
|
C22H23ClN6OS
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0402514
|
US9200001, 133
Show/Hide
|
C24H28N8
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0521541
|
US9200001, 69
Show/Hide
|
C20H21N7S
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0426303
|
US9200001, 43
Show/Hide
|
C26H28N6O3
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0555251
|
US9200001, 92
Show/Hide
|
C21H23N7
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0549922
|
US9200001, 136
Show/Hide
|
C23H25N7O
|
1
|
| 1 |
Ki = 0.42 nM
|
|
|
|
CP0418121
|
US9200001, 91
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 0.49 nM
|
|
|
|
CP0524431
|
US9062059, 3-13
Show/Hide
|
C18H20FN7O2S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0566294
|
US9200001, 42
Show/Hide
|
C26H29N7O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0518970
|
US9200001, 63
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0557579
|
US9200001, 134
Show/Hide
|
C23H25FN8
|
1
|
| 1 |
Ki = 0.58 nM
|
|
|
|
CP0506772
|
US9062059, 2-4
Show/Hide
|
C24H26N6O
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0475395
|
US8975261, TT1
Show/Hide
|
C22H22N4O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0518980
|
US9200001, 113
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 0.62 nM
|
|
|
|
CP0518971
|
US9200001, 66
Show/Hide
|
C23H27N7O2
|
1
|
| 1 |
Ki = 0.63 nM
|
|
|
|
CP0412256
|
US9200001, 112
Show/Hide
|
C22H23N7
|
1
|
| 1 |
Ki = 0.68 nM
|
|
|
|
CP0413235
|
US9200001, 132
Show/Hide
|
C22H22F2N8
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0559641
|
US9200001, 62
Show/Hide
|
C20H22N8
|
1
|
| 1 |
Ki = 0.77 nM
|
|
|
|
CP0464473
|
US8975261, I-57
Show/Hide
|
C19H20N4O2S
|
1
|
| 1 |
Ki = 0.78 nM
|
|
|
|
CP0442234
|
US8975261, I-73
Show/Hide
|
C21H22N4O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0561323
|
US9200001, 14
Show/Hide
|
C27H23N7O2
|
1
|
| 1 |
Ki = 0.82 nM
|
|
|
|
CP0555254
|
US9200001, 137
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
|
CP0518981
|
US9200001, 131
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 0.88 nM
|
|
|
|
CP0559642
|
US9200001, 67
Show/Hide
|
C23H27N7O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0518976
|
US9200001, 83
Show/Hide
|
C21H23N7
|
1
|
| 1 |
Ki = 0.96 nM
|
|
|
|
CP0488813
|
US9062059, 8-8
Show/Hide
|
C23H23N7OS
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0426304
|
US9200001, 65
Show/Hide
|
C22H25N7O2
|
1
|
| 1 |
Ki = 1.08 nM
|
|
|
|
CP0521539
|
US9200001, 64
Show/Hide
|
C21H23N7O2
|
1
|
| 1 |
Ki = 1.09 nM
|
|
|
|
CP0488814
|
US9062059, 12-2
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0506932
|
US9062059, 3-8
Show/Hide
|
C18H19FN6OS
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0490791
|
US9200001, 135
Show/Hide
|
C23H26N8O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0527313
|
US9200001, 97
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0566301
|
US9200001, 120
Show/Hide
|
C23H25N7O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0490789
|
US9200001, 119
Show/Hide
|
C21H23N7
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0506732
|
US9200001, 114
Show/Hide
|
C21H24N8
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0521546
|
US9200001, 122
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0549919
|
US9200001, 116
Show/Hide
|
C23H26N8
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0521545
|
US9200001, 111
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0564913
|
US9200001, 138
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0484147
|
US9200001, 86
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0518979
|
US9200001, 109
Show/Hide
|
C20H18F3N7
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0521538
|
US9200001, 37
Show/Hide
|
C20H21N7
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0569134
|
US9200001, 124
Show/Hide
|
C21H20F3N7O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0488815
|
US9062059, 16-4
Show/Hide
|
C19H20N8OS
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0521288
|
US9062059, 3-11
Show/Hide
|
C22H25N5OS
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0518643
|
US9200001, 130
Show/Hide
|
C20H20N8O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0518969
|
US9200001, 56
Show/Hide
|
C22H25N7
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0566300
|
US9200001, 118
Show/Hide
|
C23H28N8
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0520239
|
US9200001, 115
Show/Hide
|
C22H26N8
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0401026
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methyl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine
Show/Hide
|
C18H20ClN5OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0418120
|
US9200001, 88
Show/Hide
|
C19H18BrN7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0566302
|
US9200001, 126
Show/Hide
|
C23H27N9
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0442846
|
US9200001, 95
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0570846
|
US8975261, RR4
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0549918
|
US9200001, 79
Show/Hide
|
C25H29N7
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0960896
|
US9200001, 89
Show/Hide
|
C19H19N7
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0516742
|
US9200001, 106
Show/Hide
|
C22H25N7
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0550298
|
US9200001, 85
Show/Hide
|
C22H23N7
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0412206
|
US9200001, 93
Show/Hide
|
C20H20FN7
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0520240
|
US9200001, 121
Show/Hide
|
C24H29N9
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0536197
|
US8975261, I-54
Show/Hide
|
C17H20N6O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0559638
|
US9200001, 4
Show/Hide
|
C24H26N6O4
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0575640
|
US9062059, 2-17
Show/Hide
|
C20H22F2N6O
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0518966
|
US9200001, 36
Show/Hide
|
C20H21N7
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0488811
|
US9062059, 3-19
Show/Hide
|
C17H17ClFN7OS
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0575638
|
US9062059, 2-14
Show/Hide
|
C20H24N6O2
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0424179
|
US9062059, 2-37
Show/Hide
|
C20H22N6OS
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0424180
|
US9062059, 2-58
Show/Hide
|
C19H21ClN6OS
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0484148
|
US9200001, 96
Show/Hide
|
C25H30N8
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0479038
|
US8975261, I-55
Show/Hide
|
C20H21N5O2S
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0506731
|
US9200001, 98
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0549920
|
US9200001, 123
Show/Hide
|
C19H20N8
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0065329
|
6-chloro-2-cyclopropyl-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methylpyrimidin-4-amine
Show/Hide
|
C14H17ClN4S
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0380358
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methyl-2-propoxypyrimidin-4-amine
Show/Hide
|
C14H19ClN4OS
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0575643
|
US9062059, 14-3
Show/Hide
|
C21H23N5O
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0412207
|
US9200001, 94
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0425571
|
US9200001, 101
Show/Hide
|
C23H25N7O
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0518972
|
US9200001, 70
Show/Hide
|
C25H29N7O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0520241
|
US9200001, 127
Show/Hide
|
C21H20N6
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0920562
|
US9200001, 41
Show/Hide
|
C19H19N7
|
1
|
| 1 |
Ki = 6.8 nM
|
|
|
|
CP0407754
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-2-methoxy-5-methylpyrimidin-4-amine
Show/Hide
|
C12H15ClN4OS
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0549320
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methyl-2-(2-phenylethoxy)pyrimidin-4-amine
Show/Hide
|
C19H21ClN4OS
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0449951
|
US9200001, 77
Show/Hide
|
C19H19N7
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0897309
|
US9200001, 68
Show/Hide
|
C19H18FN7
|
1
|
| 1 |
Ki = 9.2 nM
|
|
|
|
CP0559640
|
US9200001, 29
Show/Hide
|
C23H25N7O2S
|
1
|
| 1 |
Ki = 9.8 nM
|
|
|
|
CP0520531
|
US9200001, 74
Show/Hide
|
C25H24N8
|
1
|
| 1 |
Ki = 9.9 nM
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|
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|
CP0541117
|
6-chloro-2-cyclopropyl-N-[(2-methoxy-1,3-thiazol-5-yl)methyl]-5-methylpyrimidin-4-amine
Show/Hide
|
C13H15ClN4OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0425570
|
US9200001, 87
Show/Hide
|
C22H26N8
|
1
|
| 1 |
Ki = 10.6 nM
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|
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|
CP0458412
|
2-[4-chloro-6-[(2,4-dimethyl-1,3-thiazol-5-yl)methylamino]-5-methylpyrimidin-2-yl]oxyethanol
Show/Hide
|
C13H17ClN4O2S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0418119
|
US9200001, 81
Show/Hide
|
C24H22N8
|
1
|
| 1 |
Ki = 12.8 nM
|
|
|
|
CP0530572
|
US9200001, 75
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0559643
|
US9200001, 73
Show/Hide
|
C25H24N8
|
1
|
| 1 |
Ki = 13.1 nM
|
|
|
|
CP0559434
|
US9200001, 52
Show/Hide
|
C26H25N7
|
1
|
| 1 |
Ki = 13.4 nM
|
|
|
|
CP0563958
|
US9200001, 71
Show/Hide
|
C22H25N7
|
1
|
| 1 |
Ki = 13.6 nM
|
|
|
|
CP0564912
|
US9200001, 100
Show/Hide
|
C23H27N7
|
1
|
| 1 |
Ki = 13.8 nM
|
|
|
|
CP0555252
|
US9200001, 108
Show/Hide
|
C20H21N7
|
1
|
| 1 |
Ki = 14.2 nM
|
|
|
|
CP0563290
|
US9200001, 72
Show/Hide
|
C23H28N8
|
1
|
| 1 |
Ki = 14.2 nM
|
|
|
|
CP0954491
|
US9200001, 53
Show/Hide
|
C19H18FN7
|
1
|
| 1 |
Ki = 14.2 nM
|
|
|
|
CP0905975
|
US9200001, 55
Show/Hide
|
C20H21N7
|
1
|
| 1 |
Ki = 16.8 nM
|
|
|
|
CP0487282
|
6-chloro-2-cyclopropyl-5-methyl-N-[(2-methyl-1,3-thiazol-4-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H15ClN4S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0518973
|
US9200001, 76
Show/Hide
|
C25H24N8
|
1
|
| 1 |
Ki = 18.3 nM
|
|
|
|
CP0484783
|
US9200001, 110
Show/Hide
|
C21H22N6
|
1
|
| 1 |
Ki = 18.4 nM
|
|
|
|
CP0521547
|
US9200001, 125
Show/Hide
|
C19H19N7O
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0859092
|
US9200001, 54
Show/Hide
|
C19H17F2N7
|
1
|
| 1 |
Ki = 25.1 nM
|
|
|
|
CP0384994
|
6-chloro-2-cyclopropyl-5-methyl-N-[(2-methyl-1,3-thiazol-5-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H15ClN4S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0954494
|
US9200001, 59
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 30.5 nM
|
|
|
|
CP0954492
|
US9200001, 57
Show/Hide
|
C19H18ClN7
|
1
|
| 1 |
Ki = 30.7 nM
|
|
|
|
CP0954493
|
US9200001, 58
Show/Hide
|
C20H21N7
|
1
|
| 1 |
Ki = 34.9 nM
|
|
|
|
CP0530523
|
6-chloro-2-cyclopropyl-5-methyl-N-[(1-methylpyrazol-4-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H16ClN5
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0541116
|
6-chloro-2-cyclopropyl-5-methyl-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H15ClN4O
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0555253
|
US9200001, 128
Show/Hide
|
C19H19N7
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0954596
|
US9200001, 90
Show/Hide
|
C19H19N7
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0559433
|
US9200001, 51
Show/Hide
|
C25H23N7
|
1
|
| 1 |
Ki = 38.8 nM
|
|
|
|
CP0506773
|
US9062059, 2-47
Show/Hide
|
C21H25N5OS
|
1
|
| 1 |
Ki = 41.7 nM
|
|
|
|
CP0447801
|
6-chloro-2-cyclopropyl-5-methyl-N-[(5-methyl-1,2-oxazol-3-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H15ClN4O
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0868828
|
US9200001, 60
Show/Hide
|
C20H19F2N7O
|
1
|
| 1 |
Ki = 58.2 nM
|
|
|
|
CP0518978
|
US9200001, 107
Show/Hide
|
C19H23N7
|
1
|
| 1 |
Ki = 60.7 nM
|
|
|
|
CP0569476
|
US8975261, SS1
Show/Hide
|
C20H24F2N4O2
|
1
|
| 1 |
Ki = 60.8 nM
|
|
|
|
CP0549906
|
US9200001, 9
Show/Hide
|
C24H23N7OS
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0518977
|
US9200001, 99
Show/Hide
|
C19H19N7
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0559639
|
US9200001, 27
Show/Hide
|
C23H25N7O3
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0419271
|
US9200001, 40
Show/Hide
|
C15H17N7S
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0549323
|
6-chloro-2-cyclopropyl-5-methyl-N-[(6-methylpyridin-3-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C15H17ClN4
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0538109
|
6-chloro-2-cyclopropyl-N-(2-fluoroprop-2-enyl)-5-methylpyrimidin-4-amine
Show/Hide
|
C11H13ClFN3
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0541826
|
6-chloro-2-cyclopropyl-5-methyl-N-(pyridin-4-ylmethyl)pyrimidin-4-amine
Show/Hide
|
C14H15ClN4
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0543547
|
6-chloro-2-cyclopropyl-N,5-dimethyl-N-[(1-methylpyrazol-4-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C14H18ClN5
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0429120
|
US9200001, 24
Show/Hide
|
C23H25N7O3
|
1
|
| 1 |
Ki = 248 nM
|
|
|
|
CP0483994
|
6-chloro-2-(2-cyclohexylethoxy)-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methylpyrimidin-4-amine
Show/Hide
|
C19H27ClN4OS
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0384993
|
6-chloro-2-cyclopropyl-N,5-dimethyl-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C14H17ClN4O
|
1
|
| 1 |
Ki = 540 nM
|
|
|
|
CP0384995
|
6-chloro-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methyl-2-(2-piperidin-2-ylethoxy)pyrimidin-4-amine
Show/Hide
|
C18H26ClN5OS
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0456160
|
6-chloro-2-cyclopropyl-N-(furan-3-ylmethyl)-5-methylpyrimidin-4-amine
Show/Hide
|
C13H14ClN3O
|
1
|
| 1 |
Ki = 680 nM
|
|
|
|
CP0534501
|
6-chloro-2-cyclopropyl-5-methyl-N-(1,2-oxazol-3-ylmethyl)pyrimidin-4-amine
Show/Hide
|
C12H13ClN4O
|
1
|
| 1 |
Ki = 810 nM
|
|
|
|
CP0541157
|
6-chloro-2-cyclopropyl-5-methyl-N-propylpyrimidin-4-amine
Show/Hide
|
C11H16ClN3
|
1
|
| 1 |
Ki = 880 nM
|
|
|
|
CP0380357
|
6-chloro-2-cyclopropyl-5-methyl-N-(1-pyridin-4-ylethyl)pyrimidin-4-amine
Show/Hide
|
C15H17ClN4
|
1
|
| 1 |
Ki = 890 nM
|
|
|
|
CP0425558
|
US9200001, 39
Show/Hide
|
C15H17N7O
|
1
|
| 1 |
Ki = 918 nM
|
|
|
|
CP0472523
|
6-chloro-2-cyclopropyl-5-methyl-N-(pyridin-3-ylmethyl)pyrimidin-4-amine
Show/Hide
|
C14H15ClN4
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0548841
|
6-chloro-2-cyclopropyl-5-methyl-N-(1,3-thiazol-5-ylmethyl)pyrimidin-4-amine
Show/Hide
|
C12H13ClN4S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0456159
|
6-chloro-2-cyclopropyl-N-ethyl-5-methylpyrimidin-4-amine
Show/Hide
|
C10H14ClN3
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0563568
|
5-(6-chloro-2-cyclopropyl-5-methylpyrimidin-4-yl)-2-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine
Show/Hide
|
C15H17ClN4S
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0450580
|
N-benzyl-6-chloro-2-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C15H16ClN3
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0380356
|
6-chloro-2-cyclopropyl-5-methyl-N-[2-(1-methylpyrazol-4-yl)ethyl]pyrimidin-4-amine
Show/Hide
|
C14H18ClN5
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0541155
|
6-chloro-2-cyclopropyl-5-methyl-N-[(4-methyl-1,3-thiazol-5-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H15ClN4S
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0534416
|
4-chloro-2-cyclopropyl-5-methyl-6-piperidin-1-ylpyrimidine
Show/Hide
|
C13H18ClN3
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0433366
|
6-chloro-2-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C8H10ClN3
|
1
|
| 1 |
Ki = 2200 nM
|
|
|
|
CP0512530
|
6-chloro-N-cyclopentyl-2-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C13H18ClN3
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0534417
|
6-chloro-2-cyclopropyl-5-methyl-N-propan-2-ylpyrimidin-4-amine
Show/Hide
|
C11H16ClN3
|
1
|
| 1 |
Ki = 3600 nM
|
|
|
|
CP0563236
|
4-chloro-2-cyclopropyl-5-methyl-6-piperazin-1-ylpyrimidine
Show/Hide
|
C12H17ClN4
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0528892
|
4-chloro-2-cyclopropyl-5-methyl-6-pyrrolidin-1-ylpyrimidine
Show/Hide
|
C12H16ClN3
|
1
|
| 1 |
Ki = 5300 nM
|
|
|
|
CP0384901
|
6-chloro-2-cyclopropyl-5-methyl-N-[(4-methyl-1,3-thiazol-2-yl)methyl]pyrimidin-4-amine
Show/Hide
|
C13H15ClN4S
|
1
|
| 1 |
Ki = 6800 nM
|
|
|
|
CP0452650
|
4,6-dichloro-2-cyclopropyl-5-methylpyrimidine
Show/Hide
|
C8H8Cl2N2
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
|
CP0449952
|
US9200001, 84
Show/Hide
|
C29H36N8O2
|
1
|
| 1 |
Ki > 75 nM
|
|
|
|
CP0503976
|
US9200001, 80
Show/Hide
|
C19H20N8
|
1
|
| 1 |
Ki > 75 nM
|
|
|
|
CP0518975
|
US9200001, 78
Show/Hide
|
C19H19N7O
|
1
|
| 1 |
Ki > 75 nM
|
|
|
|
CP0530573
|
US9200001, 105
Show/Hide
|
C18H19N9S
|
1
|
| 1 |
Ki > 75 nM
|
|
|
|
CP0550297
|
US9200001, 82
Show/Hide
|
C24H22N8
|
1
|
| 1 |
Ki > 75 nM
|
|
|
