Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8987315, Ketoconazole
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 PubChem ID
CID: 3823
Canonical SMILES
CC(=O)N1CCN(CC1)c1ccc(OCC2COC(Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1
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Compound Formula C26H28Cl2N4O4
Compound Structure
Protein Name
 Protein Info 
Cytochrome P450 11B1, mitochondrial
Protein Classification
Enzyme
>
Cytochrome P450
>
Cytochrome P450 family 11
>
Cytochrome P450 family 11B
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Cytochrome P450 11B1
Uniprot ID
P15538
Gene Name
CYP11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 116 nM
   TI
   LI
   LO
   TS
CL000191 V79
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 224 nM
   TI
   LI
   LO
   TS
CL000170 V79MZ
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 127 nM
   TI
   LI
   LO
   TS
CL000195 V79MZh11B1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 127 nM
   TI
   LI
   LO
   TS