| Compound ID |
Compound Name |
Compound Formula |
|
CP0007082
|
(R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
Show/Hide
|
C14H16N2O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0515708
|
4-chloro-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C17H11ClN2O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0540675
|
2-(2-fluorophenyl)-5-[(5-methoxypyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H15FN2O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0448752
|
5-[(5-methylpyridin-3-yl)methyl]-3-phenyl-1,2-thiazole
Show/Hide
|
C16H14N2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0458402
|
3-methyl-5-[(2-methyl-5-phenylpyrazol-3-yl)methyl]pyridine
Show/Hide
|
C17H17N3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0445326
|
2-phenyl-5-[(5-phenylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C23H18N2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0479538
|
6-(1-imidazol-1-yl-2-methylpropyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0105106
|
3-methyl-5-[(6-phenylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H16N2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0448749
|
5-[(5-methoxypyridin-3-yl)methyl]-3-phenyl-1,2-oxazole
Show/Hide
|
C16H14N2O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0448753
|
N-[3-[5-[(5-methylpyridin-3-yl)methyl]pyridin-2-yl]phenyl]methanesulfonamide
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0459926
|
2-(2-fluorophenyl)sulfonyl-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H15FN2O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0969394
|
(3aR,4R,7S,7aR)-3-(5-(4-cyanophenyl)pyridin-3-yl)-N-(1H-indazol-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C28H22N6O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0067385
|
6-[cyclopropyl(imidazol-1-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0134578
|
4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
Show/Hide
|
C13H10FN3
|
3
|
| 1 |
IC50 = 2.9 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
IC50 = 6 nM
|
|
|
|
CP0379574
|
1-Trityl-1H-imidazole
Show/Hide
|
C22H18N2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0547851
|
2-(2-fluorophenyl)sulfanyl-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H15FN2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0573826
|
2-(2-fluorophenyl)-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H15FN2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0684759
|
5-[3,4-Dihydro-2H-naphthalen-(1Z)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C14H14N2
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0449662
|
6-[cyclobutyl(imidazol-1-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0503624
|
1-(2,2,2-Triphenyl-ethyl)-1H-imidazole
Show/Hide
|
C23H20N2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0278531
|
6-(1-pyridin-3-ylethyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C18H18N2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0458404
|
2-(furan-3-yl)-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0574120
|
N-cyclopropyl-5-[(5-methylpyridin-3-yl)methyl]pyridin-2-amine
Show/Hide
|
C15H17N3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0415743
|
3-(imidazol-1-ylmethyl)-6-propan-2-yloxyxanthen-9-one
Show/Hide
|
C20H18N2O3
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0381970
|
6-isoquinolin-4-yl-3,4-dihydro-1H-quinazolin-2-one
Show/Hide
|
C17H13N3O
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0473823
|
3-(cyclopropylmethoxy)-6-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C21H18N2O3
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0503625
|
1-Pentamethylphenylmethyl-1H-imidazole
Show/Hide
|
C15H20N2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0523397
|
1-Adamantan-1-ylmethyl-1H-imidazole
Show/Hide
|
C14H20N2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0420156
|
3-methoxy-5-[(6-phenylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H16N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0455992
|
1-(3-methoxyphenyl)sulfonyl-6-(pyridin-3-ylmethyl)-3,4-dihydro-2H-quinoline
Show/Hide
|
C22H22N2O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0458401
|
5-[(5-methylpyridin-3-yl)methyl]-3-phenyl-1,2-oxazole
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0459924
|
3-methyl-5-[(6-phenylsulfanylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H16N2S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0508603
|
4-(cyclopropylmethoxy)-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C21H18N2O3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0446333
|
3-cyclopentyloxy-6-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C22H20N2O3
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0405946
|
4-[(6-phenylpyridin-3-yl)methyl]isoquinoline
Show/Hide
|
C21H16N2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0418593
|
1-(3-methoxyphenyl)sulfonyl-6-(pyridin-4-ylmethyl)-3,4-dihydro-2H-quinoline
Show/Hide
|
C22H22N2O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0962134
|
(3aR,4R,7S,7aR)-3-(5-(4-fluorophenyl)pyridin-3-yl)-N-(1H-indazol-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C27H22FN5O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0686649
|
5-Indan-(1Z)-ylidenemethyl-1H-imidazole
Show/Hide
|
C13H12N2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0116773
|
4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile
Show/Hide
|
C14H13N3
|
3
|
| 1 |
IC50 = 6.3 nM
|
|
|
| 2 |
IC50 = 9.7 nM
|
|
|
| 3 |
IC50 = 10 nM
|
|
|
|
CP0426066
|
6-(1-imidazol-1-ylpropyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C17H19N3O
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0554646
|
3-(imidazol-1-ylmethyl)-6-phenoxyxanthen-9-one
Show/Hide
|
C23H16N2O3
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0427551
|
3-chloro-6-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C17H11ClN2O2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0043178
|
1-((1H-imidazol-1-yl)methyl)-4-bromo-9H-xanthen-9-one
Show/Hide
|
C17H11BrN2O2
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0906724
|
5-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5,6,7,8-tetrahydro-naphthalene-2-carbonitrile
Show/Hide
|
C15H13N3
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0387510
|
6-Isoquinolin-4-yl-1-methyl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C19H16N2O
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0215527
|
3-((1H-imidazol-1-yl)methyl)-2-(4-methoxyphenyl)-4H-chromen-4-one
Show/Hide
|
C20H16N2O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0509173
|
4-methyl-3-[(6-phenylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H16N2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0969608
|
(3aR,4R,7S,7aR)-3-(5-(3-fluorophenyl)pyridin-3-yl)-N-(1H-indazol-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C27H22FN5O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0459925
|
5-[(5-methylpyridin-3-yl)methyl]-2-phenyl-1,3-thiazole
Show/Hide
|
C16H14N2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0969464
|
(3aR,4R,7S,7aR)-N-(1H-indazol-5-yl)-3-(pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0414631
|
7-fluoro-3-(1H-imidazol-5-ylmethyl)chromen-4-one
Show/Hide
|
C13H9FN2O2
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0457632
|
3-(1-Methoxyethyl)-5-(6-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C19H19NO2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0445328
|
5-[cyclopropyl(imidazol-1-yl)methyl]-2-thiophen-3-ylpyridine
Show/Hide
|
C16H15N3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0763865
|
5-[5-Fluoro-indan-(1Z)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C13H11FN2
|
1
|
| 1 |
IC50 = 11.17 nM
|
|
|
|
CP0556705
|
3-bromo-6-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C17H11BrN2O2
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
|
CP0289962
|
3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4-one
Show/Hide
|
C19H14N2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0420157
|
5-(1-imidazol-1-yl-2-methylpropyl)-2-phenylpyridine
Show/Hide
|
C18H19N3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0952074
|
(3aR,4R,7S,7aR)-3-(5-(3-cyanophenyl)pyridin-3-yl)-N-(1H-indazol-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C28H22N6O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0767912
|
1-[1-(1H-Imidazol-2-yl)-meth-(Z)-ylidene]-indan-5-carbonitrile
Show/Hide
|
C14H11N3
|
1
|
| 1 |
IC50 = 12.3 nM
|
|
|
|
CP0550892
|
3-fluoro-6-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C17H11FN2O2
|
1
|
| 1 |
IC50 = 12.3 nM
|
|
|
|
CP0466220
|
8-Isoquinolin-4-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C20H16N2O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0397406
|
6-[imidazol-1-yl(thiophen-2-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C19H17N3OS
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0508602
|
4-butan-2-yloxy-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C21H20N2O3
|
1
|
| 1 |
IC50 = 13.1 nM
|
|
|
|
CP0222291
|
1-((1H-imidazol-1-yl)methyl)-9-oxo-9H-xanthene-4-carbonitrile
Show/Hide
|
C18H11N3O2
|
1
|
| 1 |
IC50 = 13.4 nM
|
|
|
|
CP0459927
|
5-[(5-methylpyridin-3-yl)methyl]-2-phenyl-1,3-oxazole
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0519941
|
5-(imidazol-1-ylmethyl)-3-phenyl-1,2-thiazole
Show/Hide
|
C13H11N3S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0668844
|
1-[1-(3H-Imidazol-4-yl)-meth-(E)-ylidene]-indan-5-carbonitrile
Show/Hide
|
C14H11N3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0435102
|
methyl 5-(6-methoxynaphthalen-2-yl)pyridine-3-carboxylate
Show/Hide
|
C18H15NO3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0085966
|
2-methyl-1,2-dipyridin-3-ylpropan-1-one
Show/Hide
|
C14H14N2O
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 46 nM
|
|
|
|
CP0470929
|
1-Biphenyl-2-ylmethyl-1H-imidazole
Show/Hide
|
C16H14N2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0089226
|
6-isoquinolin-4-yl-1,4-dihydro-3,1-benzoxazin-2-one
Show/Hide
|
C17H12N2O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0964618
|
(3aR,4R,7S,7aR)-N-(1H-indazol-5-yl)-3-(5-(3-methoxyphenyl)pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C28H25N5O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0550893
|
4-Imidazol-1-ylmethylxanthen-9-one
Show/Hide
|
C17H12N2O2
|
1
|
| 1 |
IC50 = 15.1 nM
|
|
|
|
CP0415744
|
3-(imidazol-1-ylmethyl)-6-methoxyxanthen-9-one
Show/Hide
|
C18H14N2O3
|
1
|
| 1 |
IC50 = 15.4 nM
|
|
|
|
CP0383600
|
3-(imidazol-1-ylmethyl)-2-thiophen-2-ylpyridine
Show/Hide
|
C13H11N3S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0270829
|
6-(pyridin-3-ylmethyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C17H16N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0454545
|
2-(2-methylpyrazol-3-yl)-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C16H16N4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0383597
|
2-fluoro-4-[5-(imidazol-1-ylmethyl)pyridin-2-yl]phenol
Show/Hide
|
C15H12FN3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0423651
|
6-(1-imidazol-1-ylethyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0551966
|
5-[(2-methyl-5-phenylpyrazol-3-yl)methyl]pyridin-3-ol
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0964215
|
(3aR,4R,7S,7aR)-3-(pyridin-3-yl)-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0969609
|
(3aR,4R,7S,7aR)-N-(1H-indazol-5-yl)-3-(5-(3-(trifluoromethyl)phenyl)pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C28H22F3N5O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0699564
|
5-[7-Chloro-3,4-dihydro-2H-naphthalen-(1E)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C14H13ClN2
|
1
|
| 1 |
IC50 = 18.7 nM
|
|
|
|
CP0466108
|
1-((4-Phenylthiophen-2-yl)methyl)-1H-imidazole
Show/Hide
|
C14H12N2S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0426065
|
6-(1-imidazol-1-ylethenyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0427476
|
1-(imidazol-1-ylmethyl)-4-iodoxanthen-9-one
Show/Hide
|
C17H11IN2O2
|
1
|
| 1 |
IC50 = 19.2 nM
|
|
|
|
CP0564805
|
3-(imidazol-1-ylmethyl)-6-nitroxanthen-9-one
Show/Hide
|
C17H11N3O4
|
1
|
| 1 |
IC50 = 19.2 nM
|
|
|
|
CP0668803
|
5-[5-Chloro-indan-(1Z)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C13H11ClN2
|
1
|
| 1 |
IC50 = 19.5 nM
|
|
|
|
CP0547748
|
6-[furan-2-yl(imidazol-1-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C19H17N3O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0472363
|
2-(benzenesulfonyl)-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C18H16N2O2S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0763864
|
5-[5-Fluoro-indan-(1E)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C13H11FN2
|
1
|
| 1 |
IC50 = 20.6 nM
|
|
|
|
CP0478014
|
8-[5-(4-Methoxyphenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C23H20N2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0479866
|
5-[cyclopropyl(imidazol-1-yl)methyl]-2-phenylpyridine
Show/Hide
|
C18H17N3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0513088
|
5-(1-imidazol-1-ylethyl)-2-thiophen-3-ylpyridine
Show/Hide
|
C14H13N3S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0547850
|
4-[5-[(5-methylpyridin-3-yl)methyl]pyridin-2-yl]morpholine
Show/Hide
|
C16H19N3O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0953025
|
(3aR,4R,7S,7aR)-N-(1H-indol-5-yl)-3-(pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0266897
|
1-((1H-imidazol-1-yl)methyl)-4-nitro-9H-xanthen-9-one
Show/Hide
|
C17H11N3O4
|
1
|
| 1 |
IC50 = 22.3 nM
|
|
|
|
CP0901858
|
5-[5-Bromo-indan-(1Z)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C13H11BrN2
|
1
|
| 1 |
IC50 = 23.5 nM
|
|
|
|
CP0470927
|
1-(2,4,6-Trimethyl-benzyl)-1H-imidazole
Show/Hide
|
C13H16N2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0417661
|
1-(imidazol-1-ylmethyl)-4-(3-methylbutoxy)xanthen-9-one
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
IC50 = 24.4 nM
|
|
|
|
CP0964617
|
(3aR,4R,7S,7aR)-N-(1H-indol-6-yl)-3-(pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0417662
|
4-ethoxy-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C19H16N2O3
|
1
|
| 1 |
IC50 = 25.4 nM
|
|
|
|
CP0767945
|
5-Indan-(1E)-ylidenemethyl-1H-imidazole
Show/Hide
|
C13H12N2
|
1
|
| 1 |
IC50 = 25.9 nM
|
|
|
|
CP0508676
|
1-(3-methylphenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H20N2O2S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0735653
|
5-[5-Bromo-indan-(1E)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C13H11BrN2
|
1
|
| 1 |
IC50 = 26.2 nM
|
|
|
|
CP0074921
|
3-((1H-imidazol-1-yl)methyl)-2-(4-bromophenyl)-4H-chromen-4-one
Show/Hide
|
C19H13BrN2O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0397405
|
6-[(4-fluorophenyl)-imidazol-1-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C21H18FN3O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0420155
|
5-(1-imidazol-1-ylpropyl)-2-phenylpyridine
Show/Hide
|
C17H17N3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0413248
|
1-(3-methoxyphenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H20N2O3S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0185587
|
7-isoquinolin-4-yl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C17H12N2O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0746861
|
5-[5-Chloro-indan-(1E)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C13H11ClN2
|
1
|
| 1 |
IC50 = 28.7 nM
|
|
|
|
CP0428249
|
2,3-bis(furan-2-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C17H13N3O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0499732
|
6-[(3-fluorophenyl)-imidazol-1-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C21H18FN3O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0410494
|
5-[[6-(2-fluorophenyl)pyridin-3-yl]methyl]pyridin-3-ol
Show/Hide
|
C17H13FN2O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0399415
|
3-(1H-imidazol-5-ylmethyl)chromen-4-one
Show/Hide
|
C13H10N2O2
|
1
|
| 1 |
IC50 = 29.5 nM
|
|
|
|
CP0483768
|
3-(Methoxymethyl)-5-(6-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0964906
|
(3aR,4R,7S,7aR)-3-(5-bromopyridin-3-yl)-N-(1H-indazol-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C21H18BrN5O2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0780612
|
5-[3,4-Dihydro-2H-naphthalen-(1E)-ylidenemethyl]-1H-imidazole
Show/Hide
|
C14H14N2
|
1
|
| 1 |
IC50 = 31.4 nM
|
|
|
|
CP0470928
|
1-(3,5-Dimethyl-benzyl)-1H-imidazole
Show/Hide
|
C12H14N2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0517132
|
1-(biphenyl-4-ylmethyl)-1H-imidazole
Show/Hide
|
C16H14N2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0405944
|
2-phenyl-5-(pyridin-3-ylmethyl)pyridine
Show/Hide
|
C17H14N2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0550001
|
(1S,2R,6R,7R)-N-(3-methoxyphenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0372952
|
6-Isoquinolin-4-yl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C18H14N2O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0403976
|
5-(1-imidazol-1-ylethyl)-2-phenylpyridine
Show/Hide
|
C16H15N3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0494380
|
9-Isoquinolin-4-yl-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one
Show/Hide
|
C21H18N2O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0418986
|
1-(5-isoquinolin-4-ylindol-1-yl)ethanone
Show/Hide
|
C19H14N2O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0580138
|
(1S,2R,6R,7R)-N-(3-cyanophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0121157
|
6-[(3-chlorophenyl)-pyridin-3-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H19ClN2O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0970428
|
(3aR,4R,7S,7aR)-N-(1H-indazol-5-yl)-3-(5-(thiophen-3-yl)pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C25H21N5O2S
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0387311
|
2-phenyl-5-[[5-(trifluoromethyl)pyridin-3-yl]methyl]pyridine
Show/Hide
|
C18H13F3N2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0464717
|
8-[5-(4-Fluorophenyl)-pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H17FN2O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0400480
|
2-(1-benzothiophen-3-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C17H13N3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0449661
|
6-[(2-fluorophenyl)-imidazol-1-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C21H18FN3O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0523682
|
6-[imidazol-1-yl-(4-methoxyphenyl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C22H21N3O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0334003
|
6-(1-pyridin-3-ylethenyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C18H16N2O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0425331
|
5-(imidazol-1-ylmethyl)-2-naphthalen-1-ylpyridine
Show/Hide
|
C19H15N3
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
IC50 = 68 nM
|
|
|
|
CP0547853
|
2-(1-methylpyrazol-4-yl)-5-[(5-methylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C16H16N4
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0517136
|
1-(5-Phenyl-thiophen-2-ylmethyl)-1H-imidazole
Show/Hide
|
C14H12N2S
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0438984
|
8-[5-(2-Fluorophenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H17FN2O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0441166
|
8-[5-(3-hydroxyphenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H18N2O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0513988
|
7-phenylmethoxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C21H18N2O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0470930
|
1-Biphenyl-3-ylmethyl-1H-imidazole
Show/Hide
|
C16H14N2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0502177
|
1-(5-Phenyl-furan-2-ylmethyl)-1H-imidazole
Show/Hide
|
C14H12N2O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0572872
|
(1S,2R,6R,7R)-N-(4-cyanophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0969610
|
(3aR,4R,7S,7aR)-3-(5-(furan-3-yl)pyridin-3-yl)-N-(1H-indazol-5-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C25H21N5O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0413101
|
1-(3-Methyl-benzyl)-1H-imidazole
Show/Hide
|
C11H12N2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0561509
|
4-[(5-methylpyridin-3-yl)methyl]-3-phenyl-1,2-thiazole
Show/Hide
|
C16H14N2S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0400165
|
1-(4-fluorophenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C20H17FN2O2S
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0570975
|
(1S,2R,6R,7R)-N-(3-fluorophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0499731
|
6-[imidazol-1-yl(phenyl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C21H19N3O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0513087
|
5-[(6-phenylpyridin-3-yl)methyl]pyridin-3-ol
Show/Hide
|
C17H14N2O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0436969
|
6-(4-Methylpyridin-3-yl)-2-naphthonitrile
Show/Hide
|
C17H12N2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0384394
|
1-(5-isoquinolin-4-yl-2,3-dihydroindol-1-yl)ethanone
Show/Hide
|
C19H16N2O
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0177206
|
6-isoquinolin-4-yl-3,4-dihydro-1H-quinoxalin-2-one
Show/Hide
|
C17H13N3O
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0472364
|
4-(imidazol-1-ylmethyl)-3-phenyl-1,2-thiazole
Show/Hide
|
C13H11N3S
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0574548
|
(1S,2R,6R,7R)-N-(4-fluorophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0504797
|
8-(5-Phenylpyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]-quinolin-4-one
Show/Hide
|
C22H18N2O
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0458405
|
5-(imidazol-1-ylmethyl)-1-methyl-3-phenylpyrazole
Show/Hide
|
C14H14N4
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0452652
|
7-fluoro-3-(pyridin-4-ylmethyl)chromen-4-one
Show/Hide
|
C15H10FNO2
|
1
|
| 1 |
IC50 = 58.1 nM
|
|
|
|
CP0531493
|
5-(1-imidazol-1-ylethyl)-2-naphthalen-1-ylpyridine
Show/Hide
|
C20H17N3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0419219
|
6-pyridin-3-yl-1-thiophen-2-ylsulfonyl-3,4-dihydro-2H-quinoline
Show/Hide
|
C18H16N2O2S2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0503626
|
1-(2-Methyl-benzyl)-1H-imidazole
Show/Hide
|
C11H12N2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0417557
|
2-bromo-3-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C9H8BrN3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0440895
|
1-[5-(4-methylpyridin-3-yl)indol-1-yl]ethanone
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0383596
|
5-[5-(imidazol-1-ylmethyl)pyridin-2-yl]thiophene-2-carbaldehyde
Show/Hide
|
C14H11N3OS
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0419218
|
1-(3-chlorophenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C20H17ClN2O2S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0561506
|
5-(imidazol-1-ylmethyl)-2-phenyl-1,3-thiazole
Show/Hide
|
C13H11N3S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0483765
|
4-(6-Methoxy-3-methyl-3,4-dihydronaphthalen-2-yl)isoquinoline
Show/Hide
|
C21H19NO
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0386962
|
3-[(6-pyridin-3-yl-3,4-dihydro-2H-quinolin-1-yl)sulfonyl]benzonitrile
Show/Hide
|
C21H17N3O2S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0520271
|
1-(benzenesulfonyl)-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C20H18N2O2S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0568991
|
(1S,2R,6R,7R)-N-(3-nitrophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18N4O4
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0483764
|
4-(6-Methoxynaphthalen-2-yl)isoquinoline
Show/Hide
|
C20H15NO
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0066681
|
6-[phenyl(pyridin-3-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H20N2O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0508677
|
3-methoxy-N-methyl-N-(4-pyridin-3-ylphenyl)benzenesulfonamide
Show/Hide
|
C19H18N2O3S
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0540155
|
5-[furan-2-yl(imidazol-1-yl)methyl]-2-phenylpyridine
Show/Hide
|
C19H15N3O
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0397404
|
4-[imidazol-1-yl-(11-oxo-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-6-yl)methyl]benzonitrile
Show/Hide
|
C22H18N4O
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0310834
|
3-((1H-imidazol-1-yl)methyl)-9H-xanthen-9-one
Show/Hide
|
C17H12N2O2
|
1
|
| 1 |
IC50 = 70.8 nM
|
|
|
|
CP0480555
|
1-(3-fluorophenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C20H17FN2O2S
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0437691
|
2-(2-fluorophenyl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0417556
|
2-fluoro-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C9H8FN3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0462293
|
2-chloro-5-(imidazol-1-ylmethyl)-3-thiophen-2-ylpyridine
Show/Hide
|
C13H10ClN3S
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0373384
|
1-Adamantan-1-ylmethyl-1H-benzoimidazole
Show/Hide
|
C18H22N2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0428248
|
5-(imidazol-1-ylmethyl)-2-thiophen-2-ylpyridine
Show/Hide
|
C13H11N3S
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0425493
|
2-(furan-3-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C13H11N3O
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0551965
|
5-[(2-phenyl-1,3-thiazol-5-yl)methyl]pyridin-3-ol
Show/Hide
|
C15H12N2OS
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0067386
|
6-[(4-fluorophenyl)-pyridin-3-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H19FN2O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0198688
|
3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-phenyl-4H-chromen-4-one
Show/Hide
|
C20H16N2O3
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0569812
|
(1S,2R,6R,7R)-N-(4-methoxyphenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0379579
|
1-(3,3,3-Triphenyl-propyl)-1H-imidazole
Show/Hide
|
C24H22N2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0500490
|
1-(imidazol-1-ylmethyl)-4-methoxyxanthen-9-one
Show/Hide
|
C18H14N2O3
|
1
|
| 1 |
IC50 = 80.1 nM
|
|
|
|
CP0414630
|
7-fluoro-2-(pyridin-4-ylmethyl)chromen-4-one
Show/Hide
|
C15H10FNO2
|
1
|
| 1 |
IC50 = 82.7 nM
|
|
|
|
CP0570976
|
(1S,2R,6R,7R)-N-(4-chlorophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18ClN3O2
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0570977
|
(1S,2R,6R,7R)-N-(6-fluoropyridin-2-yl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C19H17FN4O2
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0509824
|
7-fluoro-3-(imidazol-1-ylmethyl)chromen-4-one
Show/Hide
|
C13H9FN2O2
|
1
|
| 1 |
IC50 = 86.9 nM
|
|
|
|
CP0417410
|
6-(5-methoxypyridin-3-yl)-1-methyl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C16H16N2O2
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0540917
|
4-(imidazol-1-ylmethyl)-1-phenylisoquinoline
Show/Hide
|
C19H15N3
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0282284
|
6-[(4-fluorophenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H19FN2O
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0399410
|
3-(pyridin-4-ylmethyl)chromen-4-one
Show/Hide
|
C15H11NO2
|
1
|
| 1 |
IC50 = 88.2 nM
|
|
|
|
CP0386108
|
6-[(4-chlorophenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H19ClN2O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0500488
|
1-(imidazol-1-ylmethyl)-4-propan-2-yloxyxanthen-9-one
Show/Hide
|
C20H18N2O3
|
1
|
| 1 |
IC50 = 92.5 nM
|
|
|
|
CP0425332
|
4-[5-(imidazol-1-ylmethyl)pyridin-2-yl]isoquinoline
Show/Hide
|
C18H14N4
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0571666
|
(1S,2R,6R,7R)-N-(4-nitrophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18N4O4
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0568977
|
(1S,2R,6R,7R)-N-(3-chlorophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18ClN3O2
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0445327
|
2-phenyl-5-(pyridin-4-ylmethyl)pyridine
Show/Hide
|
C17H14N2
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0483766
|
1-[5-(6-Methoxynaphthalen-2-yl)-pyridin-3-yl]ethanol
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0385116
|
1-Imidazol-1-ylmethylxanthen-9-one
Show/Hide
|
C17H12N2O2
|
1
|
| 1 |
IC50 = 99.1 nM
|
|
|
|
CP0435100
|
3-Methoxy-5-(6-methoxy-3-methyl-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C18H19NO2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0437679
|
2-[5-(imidazol-1-ylmethyl)pyridin-2-yl]aniline
Show/Hide
|
C15H14N4
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0494382
|
8-(5-Isopropoxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0508419
|
5-(imidazol-1-ylmethyl)-2-phenyl-1,3-selenazole
Show/Hide
|
C13H11N3Se
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0383985
|
4-[5-(imidazol-1-ylmethyl)pyridin-2-yl]aniline
Show/Hide
|
C15H14N4
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0952073
|
(3aR,4R,7S,7aR)-N-(1H-benzo[d]imidazol-2-yl)-3-(pyridin-3-yl)-4,5,6,7-tetrahydro-4,7-methanobenzo[d]isoxazole-7a(3aH)-carboxamide
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0372024
|
5-((1H-imidazol-1-yl)methyl)-2-phenylpyridine
Show/Hide
|
C15H13N3
|
2
|
| 1 |
IC50 = 107 nM
|
|
|
| 2 |
IC50 = 152 nM
|
|
|
|
CP0040950
|
7-[5-(2-methoxypropan-2-yl)pyridin-3-yl]-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0399412
|
3-(1H-imidazol-5-ylmethyl)-7-methoxychromen-4-one
Show/Hide
|
C14H12N2O3
|
1
|
| 1 |
IC50 = 108.9 nM
|
|
|
|
CP0400217
|
3-[5-(imidazol-1-ylmethyl)pyridin-2-yl]aniline
Show/Hide
|
C15H14N4
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0479537
|
6-[imidazol-1-yl-(3-methoxyphenyl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C22H21N3O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0389611
|
9-fluoro-7-isoquinolin-4-yl-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H15FN4
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0379376
|
1-(3-methoxyphenyl)sulfonyl-5-pyridin-3-yl-2,3-dihydroindole
Show/Hide
|
C20H18N2O3S
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0568989
|
(1S,2R,6R,7R)-N-(2-methoxyphenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0457629
|
3-(6-Methoxynaphthalen-2-yl)-4-methylpyridine
Show/Hide
|
C17H15NO
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0480557
|
4-[(6-pyridin-3-yl-3,4-dihydro-2H-quinolin-1-yl)sulfonyl]benzonitrile
Show/Hide
|
C21H17N3O2S
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0577632
|
(1S,2R,6R,7R)-N-(4-methylpyridin-3-yl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0327042
|
(R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0381968
|
6-pyridin-3-yl-3,4-dihydro-1H-quinazolin-2-one
Show/Hide
|
C13H11N3O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0455490
|
5-[(3-phenyl-1,2-oxazol-5-yl)methyl]pyridin-3-ol
Show/Hide
|
C15H12N2O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0479864
|
5-[imidazol-1-yl(phenyl)methyl]-2-phenylpyridine
Show/Hide
|
C21H17N3
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0387312
|
3-fluoro-5-[(6-phenylpyridin-3-yl)methyl]pyridine
Show/Hide
|
C17H13FN2
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0417299
|
5-(imidazol-1-ylmethyl)-2-thiophen-3-ylpyridine
Show/Hide
|
C13H11N3S
|
2
|
| 1 |
IC50 = 126 nM
|
|
|
| 2 |
IC50 = 181 nM
|
|
|
|
CP0005212
|
US8987315, Ketoconazole
Show/Hide
|
C26H28Cl2N4O4
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0372026
|
1-[1,1',3',1'']Terphenyl-5'-ylmethyl-1H-imidazole
Show/Hide
|
C22H18N2
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0438985
|
8-[5-(2-Methoxyphenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C23H20N2O2
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0574549
|
(1S,2R,6R,7R)-N-(4-methylphenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0069750
|
1-Benzylimidazole (BI)
Show/Hide
|
C10H10N2
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0570974
|
(1S,2R,6R,7R)-N-(2-fluorophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0508705
|
1-(4-chlorophenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C20H17ClN2O2S
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0458403
|
3-methyl-5-[(3-phenyl-1H-pyrazol-5-yl)methyl]pyridine
Show/Hide
|
C16H15N3
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0568449
|
(1S,2R,6R,7R)-N-(2-aminophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0423723
|
5-(imidazol-1-ylmethyl)-2-pyridin-4-ylpyridine
Show/Hide
|
C14H12N4
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0546604
|
1-methyl-7-phenylmethoxy-6-pyridin-3-yl-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H20N2O2
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0075515
|
1-(4-Chlorobenzyl)-1H-imidazole
Show/Hide
|
C10H9ClN2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0169404
|
6-(1-pyridin-4-ylethyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C18H18N2O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0473932
|
8-[5-(Trifluoromethyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C17H13F3N2O
|
1
|
| 1 |
IC50 = 141 nM
|
|
|
|
CP0423649
|
3-[imidazol-1-yl-(11-oxo-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-6-yl)methyl]benzonitrile
Show/Hide
|
C22H18N4O
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0448754
|
5-(imidazol-1-ylmethyl)-3-phenyl-1,2-oxazole
Show/Hide
|
C13H11N3O
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0547852
|
5-(imidazol-1-ylmethyl)-2-phenyl-1,3-oxazole
Show/Hide
|
C13H11N3O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0435101
|
3-(6-Methoxynaphthalen-2-yl)-5-phenylpyridine
Show/Hide
|
C22H17NO
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0513085
|
5-[cyclopropyl(imidazol-1-yl)methyl]-2-naphthalen-1-ylpyridine
Show/Hide
|
C22H19N3
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0415090
|
3-((1H-imidazol-1-yl)(4-nitrophenyl)methyl)-4H-chromen-4-one
Show/Hide
|
C19H13N3O4
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0579649
|
(1S,2R,6R,7R)-N-(3-methylphenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 153 nM
|
|
|
|
CP0410938
|
1-(imidazol-1-ylmethyl)-4-phenylxanthen-9-one
Show/Hide
|
C23H16N2O2
|
1
|
| 1 |
IC50 = 156.3 nM
|
|
|
|
CP0579650
|
(1S,2R,6R,7R)-N-(2,3-dichlorophenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H17Cl2N3O2
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0466221
|
8-(5-Ethoxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C18H18N2O2
|
1
|
| 1 |
IC50 = 158 nM
|
|
|
|
CP0440896
|
1-[5-(5-phenylpyridin-3-yl)-2,3-dihydroindol-1-yl]ethanone
Show/Hide
|
C21H18N2O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0384086
|
2-(furan-2-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C13H11N3O
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0437672
|
5-(imidazol-1-ylmethyl)-2-(2-methoxyphenyl)pyridine
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0545067
|
(1S,2R,6R,7R)-N-phenyl-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0423719
|
3-bromo-2-chloro-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C9H7BrClN3
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0373986
|
(S)Fadrozole
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 171 nM
|
|
|
|
CP0546361
|
(1S,2R,6R,7R)-5-pyridin-3-yl-N-pyrimidin-2-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C18H17N5O2
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0542147
|
3-(imidazol-1-ylmethyl)chromen-4-one
Show/Hide
|
C13H10N2O2
|
1
|
| 1 |
IC50 = 179.6 nM
|
|
|
|
CP0464705
|
8-[5-(2,5-Difluorophenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H16F2N2O
|
1
|
| 1 |
IC50 = 183 nM
|
|
|
|
CP0545069
|
(1S,2R,6R,7R)-N-methyl-N-phenyl-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 183 nM
|
|
|
|
CP0169110
|
3-((1H-imidazol-1-yl)methyl)-2-(4-nitrophenyl)-4H-chromen-4-one
Show/Hide
|
C19H13N3O4
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0517137
|
1-(3,5-Dimethyl-benzyl)-1H-benzoimidazole
Show/Hide
|
C16H16N2
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
|
CP0487734
|
3-methoxy-N-(4-pyridin-3-ylphenyl)benzenesulfonamide
Show/Hide
|
C18H16N2O3S
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
|
CP0572871
|
(1S,2R,6R,7R)-N-(2-methylphenyl)-5-pyridin-3-yl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-2-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 189 nM
|
|
|
|
CP0419103
|
6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(1H)-one
Show/Hide
|
C16H15NO2
|
1
|
| 1 |
IC50 = 191 nM
|
|
|
|
CP0368359
|
1-(3-Methyl-benzyl)-1H-benzoimidazole
Show/Hide
|
C15H14N2
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0503627
|
1-Biphenyl-4-ylmethyl-1H-benzoimidazole
Show/Hide
|
C20H16N2
|
1
|
| 1 |
IC50 = 197 nM
|
|
|
|
CP0457633
|
methyl 2-[5-(6-methoxynaphthalen-2-yl)pyridin-3-yl]acetate
Show/Hide
|
C19H17NO3
|
1
|
| 1 |
IC50 = 199 nM
|
|
|
|
CP0431686
|
2-(4-fluorophenyl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0420148
|
2-(pyridin-4-ylmethyl)chromen-4-one
Show/Hide
|
C15H11NO2
|
1
|
| 1 |
IC50 = 222.5 nM
|
|
|
|
CP0121156
|
6-(pyridin-4-ylmethyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C17H16N2O
|
1
|
| 1 |
IC50 = 224 nM
|
|
|
|
CP0482483
|
8-chloro-1-fluoro-7-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C15H9ClFNO
|
1
|
| 1 |
IC50 = 224 nM
|
|
|
|
CP0426345
|
8-chloro-7-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C15H10ClNO
|
1
|
| 1 |
IC50 = 235 nM
|
|
|
|
CP0457627
|
3-methoxy-5-(6-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
IC50 = 238 nM
|
|
|
|
CP0426341
|
8-chloro-7-isoquinolin-4-ylnaphthalen-2-ol
Show/Hide
|
C19H12ClNO
|
1
|
| 1 |
IC50 = 238 nM
|
|
|
|
CP0544321
|
5-[(6-phenylpyridin-3-yl)methyl]pyrimidine
Show/Hide
|
C16H13N3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0411320
|
8-chloro-7-(5-methoxypyridin-3-yl)naphthalen-2-ol
Show/Hide
|
C16H12ClNO2
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0500922
|
1-Phenylbenzimidazole deriv. 4
Show/Hide
|
C14H12N2
|
1
|
| 1 |
IC50 = 246 nM
|
|
|
|
CP0384063
|
4-[5-(imidazol-1-ylmethyl)pyridin-2-yl]benzaldehyde
Show/Hide
|
C16H13N3O
|
1
|
| 1 |
IC50 = 246 nM
|
|
|
|
CP0400214
|
5-(imidazol-1-ylmethyl)-2-naphthalen-2-ylpyridine
Show/Hide
|
C19H15N3
|
1
|
| 1 |
IC50 = 246 nM
|
|
|
|
CP0494381
|
8-(5-Methoxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0436972
|
3-(6-Methoxy-3-methyl-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C17H17NO
|
1
|
| 1 |
IC50 = 248 nM
|
|
|
|
CP0407425
|
2-(imidazol-1-ylmethyl)chromen-4-one
Show/Hide
|
C13H10N2O2
|
1
|
| 1 |
IC50 = 253 nM
|
|
|
|
CP0510226
|
1-[5-(6-Methoxynaphthalen-2-yl)pyridin-3-yl]ethanone
Show/Hide
|
C18H15NO2
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0360403
|
1-(4-methyl-benzyl)-1H-imidazole
Show/Hide
|
C11H12N2
|
1
|
| 1 |
IC50 = 258 nM
|
|
|
|
CP0500489
|
4-cyclopentyloxy-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C22H20N2O3
|
1
|
| 1 |
IC50 = 268.4 nM
|
|
|
|
CP0478320
|
2-(1-benzothiophen-2-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C17H13N3S
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0067380
|
6-[(2-methoxyphenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C24H22N2O2
|
1
|
| 1 |
IC50 = 276 nM
|
|
|
|
CP0419216
|
1-(4-methylphenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H20N2O2S
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
|
CP0428352
|
4'-(pyridin-4-ylmethyl)biphenyl-3-amine
Show/Hide
|
C18H16N2
|
1
|
| 1 |
IC50 = 287 nM
|
|
|
|
CP0427187
|
6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitrile
Show/Hide
|
C16H12N2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0456004
|
1-[5-(4-methylpyridin-3-yl)-2,3-dihydroindol-1-yl]propan-1-one
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
IC50 = 302 nM
|
|
|
|
CP0400169
|
6-pyridin-3-yl-1-[3-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H17F3N2O2S
|
1
|
| 1 |
IC50 = 309 nM
|
|
|
|
CP0437671
|
2-(3-fluorophenyl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0542146
|
7-fluoro-2-(imidazol-1-ylmethyl)chromen-4-one
Show/Hide
|
C13H9FN2O2
|
1
|
| 1 |
IC50 = 326.9 nM
|
|
|
|
CP0400167
|
1-(3-fluorophenyl)sulfonyl-5-pyridin-3-yl-2,3-dihydroindole
Show/Hide
|
C19H15FN2O2S
|
1
|
| 1 |
IC50 = 327 nM
|
|
|
|
CP0462295
|
2-(3,4-difluorophenyl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C15H11F2N3
|
1
|
| 1 |
IC50 = 329 nM
|
|
|
|
CP0498752
|
8-Pyridin-3-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-4-thione
Show/Hide
|
C16H14N2S
|
1
|
| 1 |
IC50 = 333 nM
|
|
|
|
CP0413247
|
1-(4-methoxyphenyl)sulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H20N2O3S
|
1
|
| 1 |
IC50 = 334 nM
|
|
|
|
CP0427188
|
6-(5-Methoxypyridin-3-yl)-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C15H14N2O2
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0506139
|
4'-(pyridin-4-ylmethyl)biphenyl-3-ol
Show/Hide
|
C18H15NO
|
1
|
| 1 |
IC50 = 342 nM
|
|
|
|
CP0248052
|
6-[hydroxy(pyridin-4-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 347 nM
|
|
|
|
CP0388317
|
3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol
Show/Hide
|
C18H14FNO
|
1
|
| 1 |
IC50 = 351 nM
|
|
|
|
CP0383595
|
5-(imidazol-1-ylmethyl)-2,3-diphenylpyridine
Show/Hide
|
C21H17N3
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0383599
|
2-(5-chlorothiophen-2-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C13H10ClN3S
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0404100
|
4-(1-chloro-7-methoxynaphthalen-2-yl)isoquinoline
Show/Hide
|
C20H14ClNO
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0384398
|
1-[5-(4-methylpyridin-3-yl)-2,3-dihydroindol-1-yl]ethanone
Show/Hide
|
C16H16N2O
|
1
|
| 1 |
IC50 = 366 nM
|
|
|
|
CP0379580
|
1-Biphenyl-3-ylmethyl-1H-benzoimidazole
Show/Hide
|
C20H16N2
|
1
|
| 1 |
IC50 = 369 nM
|
|
|
|
CP0399413
|
3-(imidazol-1-ylmethyl)-7-methoxychromen-4-one
Show/Hide
|
C14H12N2O3
|
1
|
| 1 |
IC50 = 372.1 nM
|
|
|
|
CP0485722
|
3-Ethoxy-5-(6-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 373 nM
|
|
|
|
CP0386965
|
6-pyridin-3-yl-1-[3-(trifluoromethoxy)phenyl]sulfonyl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H17F3N2O3S
|
1
|
| 1 |
IC50 = 382 nM
|
|
|
|
CP0434020
|
7-isoquinolin-4-yl-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H16N4
|
1
|
| 1 |
IC50 = 407 nM
|
|
|
|
CP0384084
|
3-[5-(imidazol-1-ylmethyl)pyridin-2-yl]benzonitrile
Show/Hide
|
C16H12N4
|
1
|
| 1 |
IC50 = 409 nM
|
|
|
|
CP0385189
|
4-hydroxy-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C17H12N2O3
|
1
|
| 1 |
IC50 = 415.8 nM
|
|
|
|
CP0405945
|
5-[(6-phenylpyridin-3-yl)methyl]pyridine-3-carboxamide
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
IC50 = 427 nM
|
|
|
|
CP0476831
|
9-fluoro-1-methyl-7-(5-phenylpyridin-3-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C22H17FN4
|
1
|
| 1 |
IC50 = 428 nM
|
|
|
|
CP0483767
|
4-(Methoxymethyl)-3-(6-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 435 nM
|
|
|
|
CP0452805
|
1-[5-(4-methylpyridin-3-yl)indol-1-yl]propan-1-one
Show/Hide
|
C17H16N2O
|
1
|
| 1 |
IC50 = 435 nM
|
|
|
|
CP0453520
|
6-[1,1-di(imidazol-1-yl)ethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
IC50 = 438 nM
|
|
|
|
CP0411321
|
3-(1-chloro-7-methoxynaphthalen-2-yl)-5-methoxypyridine
Show/Hide
|
C17H14ClNO2
|
1
|
| 1 |
IC50 = 447 nM
|
|
|
|
CP0467645
|
8-chloro-7-(5-fluoropyridin-3-yl)naphthalen-2-ol
Show/Hide
|
C15H9ClFNO
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0437506
|
6-(Pyridin-3-yl)-7,8-dihydronaphthalene-2-carbonitrile
Show/Hide
|
C16H12N2
|
1
|
| 1 |
IC50 = 461 nM
|
|
|
|
CP0530717
|
2-Imidazol-1-ylmethylxanthen-9-one
Show/Hide
|
C17H12N2O2
|
1
|
| 1 |
IC50 = 463 nM
|
|
|
|
CP0436289
|
8-[5-(3-Fluorophenyl)-pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo-[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H17FN2O
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0436290
|
8-[5-(3,4-Difluorophenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H16F2N2O
|
1
|
| 1 |
IC50 = 496 nM
|
|
|
|
CP0426036
|
1-propan-2-ylsulfonyl-5-pyridin-3-yl-2,3-dihydroindole
Show/Hide
|
C16H18N2O2S
|
1
|
| 1 |
IC50 = 499 nM
|
|
|
|
CP0128394
|
1-(4-Methyl-benzyl)-1H-benzoimidazole
Show/Hide
|
C15H14N2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0383987
|
2-(1-benzofuran-2-yl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C17H13N3O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0384088
|
2-bromo-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C9H8BrN3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0469905
|
4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine
Show/Hide
|
C18H17N3
|
1
|
| 1 |
IC50 = 502 nM
|
|
|
|
CP0482891
|
5-(imidazol-1-ylmethyl)-2-pyridin-3-ylpyridine
Show/Hide
|
C14H12N4
|
1
|
| 1 |
IC50 = 502 nM
|
|
|
|
CP0419058
|
1-(5-isoquinolin-4-yl-2,3-dihydroindol-1-yl)propan-1-one
Show/Hide
|
C20H18N2O
|
1
|
| 1 |
IC50 = 516 nM
|
|
|
|
CP0472362
|
5-(imidazol-1-ylmethyl)-1-methyl-2-phenylimidazole
Show/Hide
|
C14H14N4
|
1
|
| 1 |
IC50 = 516 nM
|
|
|
|
CP0449148
|
7-Pyridin-3-yl-2H-1,4-benzothiazin-3(4H)-one
Show/Hide
|
C13H10N2OS
|
1
|
| 1 |
IC50 = 525 nM
|
|
|
|
CP0301724
|
6-[(3-fluorophenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H19FN2O
|
1
|
| 1 |
IC50 = 532 nM
|
|
|
|
CP0425492
|
5-[5-(imidazol-1-ylmethyl)pyridin-2-yl]-2-methylaniline
Show/Hide
|
C16H16N4
|
1
|
| 1 |
IC50 = 542 nM
|
|
|
|
CP0460365
|
9-(5-Methoxypyridin-3-yl)-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one
Show/Hide
|
C18H18N2O2
|
1
|
| 1 |
IC50 = 545 nM
|
|
|
|
CP0435098
|
3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C16H15NO
|
1
|
| 1 |
IC50 = 578 nM
|
|
|
|
CP0506390
|
6-Pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione
Show/Hide
|
C14H12N2S
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0521466
|
1-(3-methoxyphenyl)sulfonyl-5-pyridin-3-yl-2,3-dihydropyrrolo[2,3-b]pyridine
Show/Hide
|
C19H17N3O3S
|
1
|
| 1 |
IC50 = 587 nM
|
|
|
|
CP0490011
|
2-(imidazol-1-ylmethyl)-5-phenylpyrazine
Show/Hide
|
C14H12N4
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0437690
|
4-[5-(imidazol-1-ylmethyl)pyridin-2-yl]-N,N-diphenylaniline
Show/Hide
|
C27H22N4
|
1
|
| 1 |
IC50 = 611 nM
|
|
|
|
CP0459508
|
7-methoxy-3-(pyridin-4-ylmethyl)chromen-4-one
Show/Hide
|
C16H13NO3
|
1
|
| 1 |
IC50 = 612.3 nM
|
|
|
|
CP0537976
|
[5-(6-methoxynaphthalen-2-yl)pyridin-3-yl]methanol
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
IC50 = 614 nM
|
|
|
|
CP0360785
|
1-(4-Chloro-benzyl)-1H-benzoimidazole
Show/Hide
|
C14H11ClN2
|
1
|
| 1 |
IC50 = 635 nM
|
|
|
|
CP0466812
|
3-(3-Benzyl-6-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C23H19NO
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0067379
|
6-[(3-chlorophenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H19ClN2O
|
1
|
| 1 |
IC50 = 646 nM
|
|
|
|
CP0145663
|
4-(1-imidazolylmethyl)pyridine
Show/Hide
|
C9H9N3
|
1
|
| 1 |
IC50 = 663 nM
|
|
|
|
CP0487736
|
1-naphthalen-2-ylsulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C24H20N2O2S
|
1
|
| 1 |
IC50 = 663 nM
|
|
|
|
CP0400166
|
1-ethylsulfonyl-5-pyridin-3-yl-2,3-dihydroindole
Show/Hide
|
C15H16N2O2S
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0251001
|
6-(pyridin-3-yl)naphthalene-2-carbonitrile
Show/Hide
|
C16H10N2
|
1
|
| 1 |
IC50 = 691 nM
|
|
|
|
CP0187015
|
8-Pyridin-3-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 715 nM
|
|
|
|
CP0384526
|
4-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]isoquinoline
Show/Hide
|
C28H23NO2
|
1
|
| 1 |
IC50 = 735 nM
|
|
|
|
CP0418987
|
1-(5-pyridin-3-ylindol-1-yl)propan-1-one
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 736 nM
|
|
|
|
CP0503539
|
1-Methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C15H14N2O
|
1
|
| 1 |
IC50 = 742 nM
|
|
|
|
CP0419105
|
6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalene-2-carbonitrile
Show/Hide
|
C16H14N2
|
1
|
| 1 |
IC50 = 745 nM
|
|
|
|
CP0248051
|
6-(hydroxy-phenyl-pyridin-4-ylmethyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H20N2O2
|
1
|
| 1 |
IC50 = 745 nM
|
|
|
|
CP0386079
|
6-[hydroxy(pyridin-3-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0387511
|
8-Chloro-6-pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione
Show/Hide
|
C14H11ClN2S
|
1
|
| 1 |
IC50 = 769 nM
|
|
|
|
CP0058618
|
4-methyl-7-pyridin-3-yl-1,4-benzoxazin-3-one
Show/Hide
|
C14H12N2O2
|
1
|
| 1 |
IC50 = 776 nM
|
|
|
|
CP0066603
|
1-(2-Methyl-benzyl)-1H-benzoimidazole
Show/Hide
|
C15H14N2
|
1
|
| 1 |
IC50 = 779 nM
|
|
|
|
CP0423721
|
4-[5-(imidazol-1-ylmethyl)pyridin-2-yl]benzonitrile
Show/Hide
|
C16H12N4
|
1
|
| 1 |
IC50 = 782 nM
|
|
|
|
CP0428250
|
5-(imidazol-1-ylmethyl)-2-(4-methoxyphenyl)pyridine
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 782 nM
|
|
|
|
CP0384527
|
4-[3-(4-Methoxybenzyl)naphthalen-2-yl]isoquinoline
Show/Hide
|
C27H21NO
|
1
|
| 1 |
IC50 = 785 nM
|
|
|
|
CP0417663
|
4-amino-1-(imidazol-1-ylmethyl)xanthen-9-one
Show/Hide
|
C17H13N3O2
|
1
|
| 1 |
IC50 = 785.3 nM
|
|
|
|
CP0103219
|
7-ethoxy-1-methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2-one
Show/Hide
|
C17H18N2O2
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0381967
|
4-methyl-6-pyridin-3-yl-1,3-dihydroquinoxalin-2-one
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 796 nM
|
|
|
|
CP0414299
|
1-[5-(5-methoxypyridin-3-yl)-2,3-dihydroindol-1-yl]ethanone
Show/Hide
|
C16H16N2O2
|
1
|
| 1 |
IC50 = 803 nM
|
|
|
|
CP0322412
|
3-(1-imidazolylmethyl)pyridine
Show/Hide
|
C9H9N3
|
1
|
| 1 |
IC50 = 816 nM
|
|
|
|
CP0423537
|
5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one
Show/Hide
|
C14H11NO
|
1
|
| 1 |
IC50 = 819 nM
|
|
|
|
CP0436975
|
4-(6-Methoxy-3-methylnaphthalen-2-yl)isoquinoline
Show/Hide
|
C21H17NO
|
1
|
| 1 |
IC50 = 843 nM
|
|
|
|
CP0423802
|
3-Methoxy-5-(6-methoxy-3-methylnaphthalen-2-yl)pyridine
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 875 nM
|
|
|
|
CP0419217
|
6-pyridin-3-yl-1-[4-(trifluoromethoxy)phenyl]sulfonyl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H17F3N2O3S
|
1
|
| 1 |
IC50 = 929 nM
|
|
|
|
CP0384518
|
3-(3-Benzylnaphthalen-2-yl)pyridine
Show/Hide
|
C22H17N
|
1
|
| 1 |
IC50 = 953 nM
|
|
|
|
CP0383601
|
5-[5-(imidazol-1-ylmethyl)pyridin-2-yl]pyrimidine
Show/Hide
|
C13H11N5
|
1
|
| 1 |
IC50 = 971 nM
|
|
|
|
CP0492202
|
3-(imidazol-1-ylmethyl)pyridine-2-carbonitrile
Show/Hide
|
C10H8N4
|
1
|
| 1 |
IC50 = 971 nM
|
|
|
|
CP0417083
|
5-(imidazol-1-ylmethyl)-2-(6-methoxypyridin-3-yl)pyridine
Show/Hide
|
C15H14N4O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0490010
|
2-phenyl-5-pyridin-3-yloxypyridine
Show/Hide
|
C16H12N2O
|
1
|
| 1 |
IC50 = 1015 nM
|
|
|
|
CP0457630
|
3-(6-Methoxy-3-methylnaphthalen-2-yl)pyridine
Show/Hide
|
C17H15NO
|
1
|
| 1 |
IC50 = 1047 nM
|
|
|
|
CP0434542
|
7-cyclopentyloxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
IC50 = 1077 nM
|
|
|
|
CP0300284
|
1-(2-methoxyphenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C22H17NO3S
|
1
|
| 1 |
IC50 = 1096 nM
|
|
|
|
CP0157834
|
7-methoxy-1-methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2-one
Show/Hide
|
C16H16N2O2
|
1
|
| 1 |
IC50 = 1098 nM
|
|
|
|
CP0405947
|
5-(imidazol-1-ylmethyl)-2-phenylpyrimidine
Show/Hide
|
C14H12N4
|
1
|
| 1 |
IC50 = 1122 nM
|
|
|
|
CP0423536
|
3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyridine
Show/Hide
|
C16H17NO
|
1
|
| 1 |
IC50 = 1145 nM
|
|
|
|
CP0426343
|
8-fluoro-7-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C15H10FNO
|
1
|
| 1 |
IC50 = 1159 nM
|
|
|
|
CP0507309
|
7-cyclopentyloxy-1-methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2-one
Show/Hide
|
C20H22N2O2
|
1
|
| 1 |
IC50 = 1167 nM
|
|
|
|
CP0413253
|
1-cyclohexylsulfonyl-6-pyridin-3-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
IC50 = 1167 nM
|
|
|
|
CP0270828
|
6-[(3-methylphenyl)-pyridin-3-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C24H22N2O
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0418592
|
6-pyridin-3-yl-1-[4-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H17F3N2O2S
|
1
|
| 1 |
IC50 = 1224 nM
|
|
|
|
CP0282285
|
6-(1-pyridin-4-ylethenyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C18H16N2O
|
1
|
| 1 |
IC50 = 1230 nM
|
|
|
|
CP0436288
|
8-(5-Fluoropyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C16H13FN2O
|
1
|
| 1 |
IC50 = 1288 nM
|
|
|
|
CP0398296
|
7-pyridin-3-yl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C13H10N2O2
|
1
|
| 1 |
IC50 = 1312 nM
|
|
|
|
CP0319245
|
6-[(3-methylphenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C24H22N2O
|
1
|
| 1 |
IC50 = 1336 nM
|
|
|
|
CP0486936
|
8-[5-(3-Methoxyphenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C23H20N2O2
|
1
|
| 1 |
IC50 = 1374 nM
|
|
|
|
CP0440897
|
1-(5-pyridin-3-ylindol-1-yl)ethanone
Show/Hide
|
C15H12N2O
|
1
|
| 1 |
IC50 = 1379 nM
|
|
|
|
CP0411840
|
4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol
Show/Hide
|
C18H15NO2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0531118
|
3-(1-chloro-7-methoxynaphthalen-2-yl)-5-fluoropyridine
Show/Hide
|
C16H11ClFNO
|
1
|
| 1 |
IC50 = 1415 nM
|
|
|
|
CP0142269
|
6-(2-methyl-1-pyridin-4-ylpropyl)-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C20H22N2O
|
1
|
| 1 |
IC50 = 1420 nM
|
|
|
|
CP0405080
|
8-bromo-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C14H11BrN2O
|
1
|
| 1 |
IC50 = 1422 nM
|
|
|
|
CP0452806
|
cyclopropyl-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)methanone
Show/Hide
|
C17H16N2O
|
1
|
| 1 |
IC50 = 1423 nM
|
|
|
|
CP0436971
|
3-(6-Methoxynaphthalen-2-yl)pyridin-4-amine
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 1521 nM
|
|
|
|
CP0455997
|
2-phenyl-1-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)ethanone
Show/Hide
|
C21H18N2O
|
1
|
| 1 |
IC50 = 1523 nM
|
|
|
|
CP0179960
|
3-(6-Methoxy-2-naphthyl)pyridine
Show/Hide
|
C16H13NO
|
1
|
| 1 |
IC50 = 1577 nM
|
|
|
|
CP0459509
|
2-(imidazol-1-ylmethyl)-7-methoxychromen-4-one
Show/Hide
|
C14H12N2O3
|
1
|
| 1 |
IC50 = 1600.8 nM
|
|
|
|
CP0467689
|
3-(1-fluoro-7-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C16H12FNO
|
1
|
| 1 |
IC50 = 1609 nM
|
|
|
|
CP0035494
|
(1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-7,13-dien-5-ol
Show/Hide
|
C24H31NO
|
1
|
| 1 |
IC50 = 1610 nM
|
|
|
|
CP0419104
|
8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C14H11ClN2O
|
1
|
| 1 |
IC50 = 1671 nM
|
|
|
|
CP0386964
|
1-methylsulfonyl-5-pyridin-3-yl-2,3-dihydroindole
Show/Hide
|
C14H14N2O2S
|
1
|
| 1 |
IC50 = 1674 nM
|
|
|
|
CP0247849
|
6-pyridin-3-yl-1,4-dihydro-3,1-benzoxazin-2-one
Show/Hide
|
C13H10N2O2
|
1
|
| 1 |
IC50 = 1692 nM
|
|
|
|
CP0490012
|
3-(imidazol-1-ylmethyl)-6-phenylpyridazine
Show/Hide
|
C14H12N4
|
1
|
| 1 |
IC50 = 1711 nM
|
|
|
|
CP0509489
|
8-[5-(3,5-Difluorophenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C22H16F2N2O
|
1
|
| 1 |
IC50 = 1748 nM
|
|
|
|
CP0508678
|
1-(3-methoxyphenyl)sulfonyl-5-pyridin-4-yl-2,3-dihydropyrrolo[2,3-b]pyridine
Show/Hide
|
C19H17N3O3S
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0460368
|
[3-(6-methoxynaphthalen-2-yl)pyridin-4-yl]methanol
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
IC50 = 1760 nM
|
|
|
|
CP0322430
|
9-fluoro-1-methyl-7-(4-methylpyridin-3-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H15FN4
|
1
|
| 1 |
IC50 = 1770 nM
|
|
|
|
CP0478592
|
9-fluoro-7-(5-methoxypyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H15FN4O
|
1
|
| 1 |
IC50 = 1810 nM
|
|
|
|
CP0415088
|
3-Methoxy-5-[3-(4-methoxybenzyl)naphthalen-2-yl]pyridine
Show/Hide
|
C24H21NO2
|
1
|
| 1 |
IC50 = 1811 nM
|
|
|
|
CP0401634
|
4-(3-Pyridin-3-yl-naphthalen-2-ylmethyl)benzonitrile
Show/Hide
|
C23H16N2
|
1
|
| 1 |
IC50 = 1956 nM
|
|
|
|
CP0502214
|
3-(5,6,7,8-Tetrahydronaphthalen-2-yl)pyridine
Show/Hide
|
C15H15N
|
1
|
| 1 |
IC50 = 1977 nM
|
|
|
|
CP0471053
|
3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-4-ol
Show/Hide
|
C21H18FNO
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0386963
|
N-benzyl-3-methoxy-N-(4-pyridin-3-ylphenyl)benzenesulfonamide
Show/Hide
|
C25H22N2O3S
|
1
|
| 1 |
IC50 = 2001 nM
|
|
|
|
CP0480556
|
1-(2-methylpropylsulfonyl)-5-pyridin-3-yl-2,3-dihydroindole
Show/Hide
|
C17H20N2O2S
|
1
|
| 1 |
IC50 = 2003 nM
|
|
|
|
CP0473966
|
8-(5-Hydroxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C16H14N2O2
|
1
|
| 1 |
IC50 = 2045 nM
|
|
|
|
CP0441167
|
8-{5-[3-(Trifluoromethoxy)phenyl]pyridin-3-yl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C23H17F3N2O2
|
1
|
| 1 |
IC50 = 2058 nM
|
|
|
|
CP0501610
|
8-Imidazol-1-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 2077 nM
|
|
|
|
CP0121158
|
6-[(2-methoxyphenyl)-pyridin-3-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C24H22N2O2
|
1
|
| 1 |
IC50 = 2270 nM
|
|
|
|
CP0160421
|
9-Pyridin-3-yl-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one
Show/Hide
|
C17H16N2O
|
1
|
| 1 |
IC50 = 2296 nM
|
|
|
|
CP0400168
|
(3-methoxyphenyl)-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)methanone
Show/Hide
|
C21H18N2O2
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0479869
|
8-chloro-7-pyrimidin-5-ylnaphthalen-2-ol
Show/Hide
|
C14H9ClN2O
|
1
|
| 1 |
IC50 = 2426 nM
|
|
|
|
CP0531966
|
3-Methoxy-5-[6-methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]pyridine
Show/Hide
|
C25H23NO3
|
1
|
| 1 |
IC50 = 2452 nM
|
|
|
|
CP0115070
|
6-[(3-methoxyphenyl)-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C24H22N2O2
|
1
|
| 1 |
IC50 = 2539 nM
|
|
|
|
CP0055110
|
4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
Show/Hide
|
C17H11N5
|
1
|
| 1 |
IC50 = 2620 nM
|
|
|
|
CP0435139
|
3-[3-(4-Methoxybenzyl)naphthalen-2-yl]pyridine
Show/Hide
|
C23H19NO
|
1
|
| 1 |
IC50 = 2804 nM
|
|
|
|
CP0498579
|
5-(1-chloro-7-hydroxynaphthalen-2-yl)pyridin-3-ol
Show/Hide
|
C15H10ClNO2
|
1
|
| 1 |
IC50 = 2824 nM
|
|
|
|
CP0413250
|
1-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)ethanone
Show/Hide
|
C15H14N2O
|
1
|
| 1 |
IC50 = 2848 nM
|
|
|
|
CP0405081
|
7-methoxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C15H14N2O2
|
1
|
| 1 |
IC50 = 2867 nM
|
|
|
|
CP0445492
|
3-(1-chloro-8-fluoro-7-methoxynaphthalen-2-yl)pyridine
Show/Hide
|
C16H11ClFNO
|
1
|
| 1 |
IC50 = 2935 nM
|
|
|
|
CP0384520
|
3-(3-Benzyl-6-methoxynaphthalen-2-yl)5-methoxypyridine
Show/Hide
|
C24H21NO2
|
1
|
| 1 |
IC50 = 2936 nM
|
|
|
|
CP0405583
|
4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-3-ol
Show/Hide
|
C21H19NO
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0447108
|
1-[5-(1-acetyl-2,3-dihydroindol-5-yl)pyridin-3-yl]ethanone
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 3125 nM
|
|
|
|
CP0444830
|
6-pyridin-3-yl-3,4-dihydro-1H-quinoxalin-2-one
Show/Hide
|
C13H11N3O
|
1
|
| 1 |
IC50 = 3451 nM
|
|
|
|
CP0384521
|
3-[3-(4-Trifluoromethoxybenzyl)naphthalen-2-yl]pyridine
Show/Hide
|
C23H16F3NO
|
1
|
| 1 |
IC50 = 3559 nM
|
|
|
|
CP0547417
|
9-fluoro-1-methyl-7-[5-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H12F4N4
|
1
|
| 1 |
IC50 = 3570 nM
|
|
|
|
CP0420147
|
7-methoxy-2-(pyridin-4-ylmethyl)chromen-4-one
Show/Hide
|
C16H13NO3
|
1
|
| 1 |
IC50 = 3598.4 nM
|
|
|
|
CP0452803
|
cyclopropyl-(5-isoquinolin-4-yl-2,3-dihydroindol-1-yl)methanone
Show/Hide
|
C21H18N2O
|
1
|
| 1 |
IC50 = 3723 nM
|
|
|
|
CP0476876
|
7-ethoxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C16H16N2O2
|
1
|
| 1 |
IC50 = 3737 nM
|
|
|
|
CP0420364
|
1-[5-[5-(1-hydroxyethyl)pyridin-3-yl]-2,3-dihydroindol-1-yl]ethanone
Show/Hide
|
C17H18N2O2
|
1
|
| 1 |
IC50 = 3756 nM
|
|
|
|
CP0428747
|
1-[5-(9-fluoro-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]ethanol
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
IC50 = 3910 nM
|
|
|
|
CP0372951
|
6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one
Show/Hide
|
C15H13NO
|
1
|
| 1 |
IC50 = 3964 nM
|
|
|
|
CP0476875
|
6,8-dipyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C19H15N3O
|
1
|
| 1 |
IC50 = 4087 nM
|
|
|
|
CP0384402
|
2-methyl-1-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)propan-1-one
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0117413
|
1-(4-methoxyphenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C22H17NO3S
|
1
|
| 1 |
IC50 = 4196 nM
|
|
|
|
CP0160422
|
3-[6-Methoxy-3-(4-methoxybenzyl)naphthalen-2-yl]pyridine
Show/Hide
|
C24H21NO2
|
1
|
| 1 |
IC50 = 4329 nM
|
|
|
|
CP0387509
|
3-(6-Ethoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyridine
Show/Hide
|
C17H19NO
|
1
|
| 1 |
IC50 = 4371 nM
|
|
|
|
CP0250521
|
1-(2-chlorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H14ClNO2S
|
1
|
| 1 |
IC50 = 4487 nM
|
|
|
|
CP0530505
|
9-fluoro-7-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H14F2N4
|
1
|
| 1 |
IC50 = 4520 nM
|
|
|
|
CP0434541
|
6-pyridin-3-yl-8-thiophen-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C18H14N2OS
|
1
|
| 1 |
IC50 = 4589 nM
|
|
|
|
CP0478737
|
8-{5-[3-(Trifluoromethyl)phenyl]pyridin-3-yl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C23H17F3N2O
|
1
|
| 1 |
IC50 = 4646 nM
|
|
|
|
CP0536686
|
3-pyridin-3-yl-1-[2-(trifluoromethoxy)phenyl]sulfinylnaphthalen-2-ol
Show/Hide
|
C22H14F3NO3S
|
1
|
| 1 |
IC50 = 4710 nM
|
|
|
|
CP0413673
|
1-(3,5-dichlorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H13Cl2NO2S
|
1
|
| 1 |
IC50 = 4717 nM
|
|
|
|
CP0420362
|
1-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)propan-1-one
Show/Hide
|
C16H16N2O
|
1
|
| 1 |
IC50 = 4737 nM
|
|
|
|
CP0418797
|
1-(3-chlorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H14ClNO2S
|
1
|
| 1 |
IC50 = 4797 nM
|
|
|
|
CP0387507
|
6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol
Show/Hide
|
C15H15NO
|
1
|
| 1 |
IC50 = 4921 nM
|
|
|
|
CP0411836
|
6-(4-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)phenyl)naphthalen-2-ol
Show/Hide
|
C25H21NO
|
1
|
| 1 |
IC50 = 5060 nM
|
|
|
|
CP0268020
|
3-pyridin-3-yl-1-[2-(trifluoromethyl)phenyl]sulfinylnaphthalen-2-ol
Show/Hide
|
C22H14F3NO2S
|
1
|
| 1 |
IC50 = 5076 nM
|
|
|
|
CP0341241
|
1-Ethyl-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C16H16N2O
|
1
|
| 1 |
IC50 = 5177 nM
|
|
|
|
CP0121154
|
6-[phenyl(pyridin-4-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H20N2O
|
1
|
| 1 |
IC50 = 5399 nM
|
|
|
|
CP0452537
|
8-Nitro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C14H11N3O3
|
1
|
| 1 |
IC50 = 5402 nM
|
|
|
|
CP0128971
|
1-(4-fluorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H14FNO2S
|
1
|
| 1 |
IC50 = 5549 nM
|
|
|
|
CP0487746
|
9-fluoro-7-(5-fluoro-4-methylpyridin-3-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H12F2N4
|
1
|
| 1 |
IC50 = 5705 nM
|
|
|
|
CP0300285
|
3-pyridin-3-yl-1-[3-(trifluoromethoxy)phenyl]sulfinylnaphthalen-2-ol
Show/Hide
|
C22H14F3NO3S
|
1
|
| 1 |
IC50 = 5812 nM
|
|
|
|
CP0055292
|
3-(2-Naphthyl)pyridine
Show/Hide
|
C15H11N
|
1
|
| 1 |
IC50 = 5826 nM
|
|
|
|
CP0452539
|
5-Pyridin-3-yl-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C13H10N2O
|
1
|
| 1 |
IC50 = 5952 nM
|
|
|
|
CP0493305
|
4-Methyl-7-pyridin-3-yl-3,4-dihydro-2H-1,4-benzoxazine
Show/Hide
|
C14H14N2O
|
1
|
| 1 |
IC50 = 5970 nM
|
|
|
|
CP0420363
|
1-(5-isoquinolin-4-yl-2,3-dihydroindol-1-yl)-2-methylpropan-1-one
Show/Hide
|
C21H20N2O
|
1
|
| 1 |
IC50 = 6093 nM
|
|
|
|
CP0343834
|
3-pyridin-3-yl-1-thiophen-2-ylsulfinylnaphthalen-2-ol
Show/Hide
|
C19H13NO2S2
|
1
|
| 1 |
IC50 = 6164 nM
|
|
|
|
CP0128972
|
3-pyridin-3-yl-1-[4-(trifluoromethyl)phenyl]sulfinylnaphthalen-2-ol
Show/Hide
|
C22H14F3NO2S
|
1
|
| 1 |
IC50 = 6189 nM
|
|
|
|
CP0377737
|
1-(3-chloro-4-fluorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H13ClFNO2S
|
1
|
| 1 |
IC50 = 6534 nM
|
|
|
|
CP0268019
|
1-(3-fluorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H14FNO2S
|
1
|
| 1 |
IC50 = 6548 nM
|
|
|
|
CP0452804
|
5-(1-acetyl-2,3-dihydroindol-5-yl)pyridine-3-carbonitrile
Show/Hide
|
C16H13N3O
|
1
|
| 1 |
IC50 = 6642 nM
|
|
|
|
CP0335034
|
3-pyridin-3-yl-1-[3-(trifluoromethyl)phenyl]sulfinylnaphthalen-2-ol
Show/Hide
|
C22H14F3NO2S
|
1
|
| 1 |
IC50 = 6674 nM
|
|
|
|
CP0247771
|
1-(benzenesulfinyl)-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H15NO2S
|
1
|
| 1 |
IC50 = 6712 nM
|
|
|
|
CP0259148
|
6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C14H12N2O
|
1
|
| 1 |
IC50 = 6746 nM
|
|
|
|
CP0456003
|
1-[5-(5-fluoropyridin-3-yl)-2,3-dihydroindol-1-yl]ethanone
Show/Hide
|
C15H13FN2O
|
1
|
| 1 |
IC50 = 6812 nM
|
|
|
|
CP0448894
|
9-chloro-7-(4-cyclopropylpyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C19H17ClN4
|
1
|
| 1 |
IC50 = 6930 nM
|
|
|
|
CP0481198
|
1-[5-(9-fluoro-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]ethanone
Show/Hide
|
C18H15FN4O
|
1
|
| 1 |
IC50 = 6970 nM
|
|
|
|
CP0473718
|
5-(1-chloro-7-methoxynaphthalen-2-yl)pyridin-3-ol
Show/Hide
|
C16H12ClNO2
|
1
|
| 1 |
IC50 = 7099 nM
|
|
|
|
CP0418476
|
4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-3,4-diamine
Show/Hide
|
C21H21N3
|
1
|
| 1 |
IC50 = 7180 nM
|
|
|
|
CP0411834
|
4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-3-amine
Show/Hide
|
C21H20N2
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0492415
|
1-(3-methoxyphenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C22H17NO3S
|
1
|
| 1 |
IC50 = 7315 nM
|
|
|
|
CP0463270
|
3-pyridin-3-yl-1-[4-(trifluoromethoxy)phenyl]sulfinylnaphthalen-2-ol
Show/Hide
|
C22H14F3NO3S
|
1
|
| 1 |
IC50 = 7427 nM
|
|
|
|
CP0398297
|
1-methyl-6-pyridin-3-yl-4,2lambda6,1-benzoxathiazine 2,2-dioxide
Show/Hide
|
C13H12N2O3S
|
1
|
| 1 |
IC50 = 7483 nM
|
|
|
|
CP0263990
|
8-fluoro-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C15H11FN4
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0247772
|
1-(3,4-dichlorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H13Cl2NO2S
|
1
|
| 1 |
IC50 = 8333 nM
|
|
|
|
CP0398768
|
3-(2-hydroxy-3-pyridin-3-ylnaphthalen-1-yl)sulfinylbenzonitrile
Show/Hide
|
C22H14N2O2S
|
1
|
| 1 |
IC50 = 8550 nM
|
|
|
|
CP0500840
|
5-(6-Methoxynaphthalen-2-yl)pyridin-3-ol
Show/Hide
|
C16H13NO2
|
1
|
| 1 |
IC50 = 8925 nM
|
|
|
|
CP0418155
|
1-(4-chlorophenyl)sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C21H14ClNO2S
|
1
|
| 1 |
IC50 = 8947 nM
|
|
|
|
CP0413672
|
1-[3,5-bis(trifluoromethyl)phenyl]sulfinyl-3-pyridin-3-ylnaphthalen-2-ol
Show/Hide
|
C23H13F6NO2S
|
1
|
| 1 |
IC50 = 9346 nM
|
|
|
|
CP0401631
|
4-(3-Pyridin-3-yl-naphthalene-2-carbonyl)benzonitrile
Show/Hide
|
C23H14N2O
|
1
|
| 1 |
IC50 = 9639 nM
|
|
|
|
CP0459995
|
8-chloro-7-isoquinolin-4-yl-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H15ClN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0500388
|
8-fluoro-7-(4-methoxy-5-methylpyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0380799
|
8-fluoro-1-propan-2-yl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C18H17FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0381965
|
1-ethyl-9-fluoro-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H15FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0381966
|
1-ethyl-8-fluoro-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H15FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400690
|
8-fluoro-1-phenyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C21H15FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414341
|
1-benzyl-8-fluoro-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C22H17FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414614
|
8-fluoro-7-pyridin-3-yl-1-pyridin-4-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H14FN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0478591
|
5-(9-fluoro-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridine-3-carbonitrile
Show/Hide
|
C17H12FN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0480594
|
9-fluoro-7-(5-fluoropyridin-3-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C15H10F2N4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0488281
|
9-fluoro-1-phenyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C21H15FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0488282
|
9-fluoro-7-pyridin-3-yl-1-pyridin-4-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H14FN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0499183
|
9-fluoro-1-propan-2-yl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C18H17FN4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0547418
|
(9-fluoro-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-phenylmethanone
Show/Hide
|
C22H15FN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401800
|
2-(pyridin-3-ylmethyl)chromen-4-one
Show/Hide
|
C15H11NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420254
|
7-fluoro-2-(pyridin-3-ylmethyl)chromen-4-one
Show/Hide
|
C15H10FNO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0448073
|
3-(pyridin-3-ylmethyl)chromen-4-one
Show/Hide
|
C15H11NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0448080
|
7-methoxy-3-(pyridin-3-ylmethyl)chromen-4-one
Show/Hide
|
C16H13NO3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459512
|
7-methoxy-2-(pyridin-3-ylmethyl)chromen-4-one
Show/Hide
|
C16H13NO3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459552
|
7-fluoro-3-(pyridin-3-ylmethyl)chromen-4-one
Show/Hide
|
C15H10FNO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0373370
|
(3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethoxyphenyl)-methanone
Show/Hide
|
C23H14F3NO2
|
1
|
| 1 |
IC50 = 11307 nM
|
|
|
|
CP0482437
|
7-hydroxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C14H12N2O2
|
1
|
| 1 |
IC50 = 11940 nM
|
|
|
|
CP0494259
|
5-(1-chloro-7-methoxynaphthalen-2-yl)pyrimidine
Show/Hide
|
C15H11ClN2O
|
1
|
| 1 |
IC50 = 12286 nM
|
|
|
|
CP0149815
|
8-fluoro-1-methyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
IC50 = 12620 nM
|
|
|
|
CP0452538
|
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)pyridine
Show/Hide
|
C13H11NO2
|
1
|
| 1 |
IC50 = 13378 nM
|
|
|
|
CP0134182
|
9-fluoro-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C15H11FN4
|
1
|
| 1 |
IC50 = 16100 nM
|
|
|
|
CP0507308
|
8-phenyl-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C20H16N2O
|
1
|
| 1 |
IC50 = 16170 nM
|
|
|
|
CP0353826
|
9-fluoro-1-methyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
IC50 = 16990 nM
|
|
|
|
CP0469408
|
7-(4-ethyl-5-fluoropyridin-3-yl)-8,9-difluoro-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C18H15F3N4
|
1
|
| 1 |
IC50 = 17296 nM
|
|
|
|
CP0435149
|
(3-Fluoro-4-methoxyphenyl)(3-pyridin-3-yl-naphthalen-2-yl)-methanone
Show/Hide
|
C23H16FNO2
|
1
|
| 1 |
IC50 = 19816 nM
|
|
|
|
CP0384524
|
(4-Methoxyphenyl)(3-pyridin-3-yl-naphthalen-2-yl)methanone
Show/Hide
|
C23H17NO2
|
1
|
| 1 |
IC50 = 24003 nM
|
|
|
|
CP0462946
|
8-Pyrimidin-5-yl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
IC50 = 28546 nM
|
|
|
|
CP0118237
|
9-fluoro-7-(5-fluoropyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H12F2N4
|
1
|
| 1 |
IC50 = 29540 nM
|
|
|
|
CP0459994
|
9-chloro-1-methyl-7-[4-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H12ClF3N4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0400219
|
4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-3,4-diol
Show/Hide
|
C21H19NO2
|
1
|
| 1 |
IC50 = 37470 nM
|
|
|
|
CP0498091
|
2-[5-(6-methoxynaphthalen-2-yl)pyridin-3-yl]acetic acid
Show/Hide
|
C18H15NO3
|
1
|
| 1 |
IC50 = 37796 nM
|
|
|
|
CP0474084
|
5-(6-Methoxynaphthalen-2-yl)pyridine-3-carboxamide
Show/Hide
|
C17H14N2O2
|
1
|
| 1 |
IC50 = 41557 nM
|
|
|
|
CP0371109
|
1-(2,4,6-Trimethyl-benzyl)-1H-benzoimidazole
Show/Hide
|
C17H18N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0372602
|
1-(3,3,3-Triphenyl-propyl)-1H-benzoimidazole
Show/Hide
|
C28H24N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0379581
|
1-[1,1',3',1'']Terphenyl-5'-ylmethyl-1H-benzoimidazole
Show/Hide
|
C26H20N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0466109
|
1-Biphenyl-2-ylmethyl-1H-benzoimidazole
Show/Hide
|
C20H16N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0503629
|
1-Trityl-1H-benzoimidazole
Show/Hide
|
C26H20N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0517140
|
1-(2,2,2-Triphenyl-ethyl)-1H-benzoimidazole
Show/Hide
|
C27H22N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0522138
|
1-Pentamethylphenylmethyl-1H-benzoimidazole
Show/Hide
|
C19H22N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0469624
|
2-(3,4-dimethoxyphenyl)-5-(imidazol-1-ylmethyl)pyridine
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0121151
|
6-[[3,5-bis(trifluoromethyl)phenyl]-pyridin-4-ylmethyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C25H18F6N2O
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0142268
|
6-[cyclohexyl(pyridin-4-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C23H26N2O
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0467655
|
6-phenyl-N-pyridin-3-ylpyridin-3-amine
Show/Hide
|
C16H13N3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0384403
|
(4-fluorophenyl)-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)methanone
Show/Hide
|
C20H15FN2O
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0419060
|
3-chloro-1-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)propan-1-one
Show/Hide
|
C16H15ClN2O
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0456002
|
(4-methoxyphenyl)-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)methanone
Show/Hide
|
C21H18N2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0469028
|
(5-pyridin-3-yl-2,3-dihydroindol-1-yl)-thiophen-2-ylmethanone
Show/Hide
|
C18H14N2OS
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0487735
|
1-(3-methoxyphenyl)sulfonyl-6-pyridin-4-yl-3,4-dihydro-2H-quinoline
Show/Hide
|
C21H20N2O3S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
