| Compound ID |
Compound Name |
Compound Formula |
|
CP0506020
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxylate
Show/Hide
|
C35H45N7O4
|
1
|
| 1 |
IC50 = 0.01 nM
|
|
|
|
CP0506535
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxylate
Show/Hide
|
C35H44FN7O4
|
1
|
| 1 |
IC50 = 0.011 nM
|
|
|
|
CP0504736
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H44N6O4
|
1
|
| 1 |
IC50 = 0.017 nM
|
|
|
|
CP0503896
|
(R)-1-(4-cyclohexylpiperazin-1-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H44N6O4
|
1
|
| 1 |
IC50 = 0.02 nM
|
|
|
|
CP0506525
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(7-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxylate
Show/Hide
|
C35H44FN7O4
|
1
|
| 1 |
IC50 = 0.022 nM
|
|
|
|
CP0498464
|
(2R)-3-(7-methyl-1H-indazol-5-yl)-1-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H44N6O4
|
1
|
| 1 |
IC50 = 0.044 nM
|
|
|
|
CP0547515
|
(R)-1-(4-(5,6-dihydropyridin-1(2H)-yl)piperidin-1-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H42N6O4
|
1
|
| 1 |
IC50 = 0.053 nM
|
|
|
|
CP0547514
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(8-fluoro-2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H43FN6O4
|
1
|
| 1 |
IC50 = 0.057 nM
|
|
|
|
CP0538696
|
(R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C35H37N7O4
|
1
|
| 1 |
IC50 = 0.063 nM
|
|
|
|
CP0538694
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(2-oxo-4-phenyl-2,3-dihydro-1H-imidazol-1-yl)piperidine-1-carboxylate
Show/Hide
|
C36H45N7O4
|
1
|
| 1 |
IC50 = 0.068 nM
|
|
|
|
CP0505740
|
(R)-1-(4-(4-fluorophenyl)piperazin-1-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H37FN6O4
|
1
|
| 1 |
IC50 = 0.13 nM
|
|
|
|
CP0538693
|
(R)-1-(1,4'-bipiperidin-1'-yl)-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl 4-(isoquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C36H44N6O3
|
1
|
| 1 |
IC50 = 0.18 nM
|
|
|
|
CP0426939
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-[2-(trifluoromethoxy)ethyl]azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C27H29F5N6O4
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 6 nM
|
|
|
|
CP0538695
|
(R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(piperidin-1-yl)propan-2-yl 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxylate
Show/Hide
|
C31H35N5O4
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0439439
|
N-[(3R,6S)-1-(cyclopropylmethyl)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C28H32F2N6O3
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 21 nM
|
|
|
|
CP0454992
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methoxyethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C27H32F2N6O4
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0461001
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(pyridin-2-ylmethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C30H31F2N7O3
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0485262
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methylsulfanylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C27H32F2N6O3S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0461000
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methylsulfonylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C27H32F2N6O5S
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0024947
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C26H27F5N6O3
|
2
|
| 1 |
IC50 = 2.2 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0485264
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-morpholin-4-ylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C30H37F2N7O4
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0426974
|
N-[(3R,6S)-1-(2,2-difluoroethyl)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C26H28F4N6O3
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0439442
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-fluoroethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C26H29F3N6O3
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0426972
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methylsulfinylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C27H32F2N6O4S
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0463964
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-ethyl-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C26H30F2N6O3
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0424316
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-methyl-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C25H28F2N6O3
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0454991
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-[2-(dimethylamino)ethyl]-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C28H35F2N7O3
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0461002
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C24H26F2N6O3
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0435193
|
N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-hydroxyethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C26H30F2N6O4
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0442300
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-(1,3-thiazol-2-yl)benzimidazol-1-yl]acetamide
Show/Hide
|
C24H20N6O4S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0471394
|
N-[(3R,6S)-1-(cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
|
CP0521189
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-(1,2-thiazol-4-yl)benzimidazol-1-yl]acetamide
Show/Hide
|
C24H20N6O4S
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0442422
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-[4-(trifluoromethyl)pyrimidin-2-yl]benzimidazol-1-yl]acetamide
Show/Hide
|
C26H20F3N7O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0445970
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-3-pyrimidin-5-ylbenzimidazol-1-yl)acetamide
Show/Hide
|
C25H21N7O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0382911
|
2-[3-(6-methoxypyridin-2-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide
Show/Hide
|
C27H24N6O5
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0401977
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-(oxolan-3-yl)benzimidazol-1-yl]acetamide
Show/Hide
|
C25H25N5O5
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0442298
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-3-pyrazin-2-ylbenzimidazol-1-yl)acetamide
Show/Hide
|
C25H21N7O4
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0442424
|
2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide
Show/Hide
|
C25H25N5O6S
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0484250
|
N-[(3R,6S)-6-(2-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C24H27FN6O3
|
2
|
| 1 |
IC50 = 65 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0179406
|
(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide
Show/Hide
|
C26H22N6O4
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0503898
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-3-pyrimidin-2-ylbenzimidazol-1-yl)acetamide
Show/Hide
|
C25H21N7O4
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0409265
|
(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide
Show/Hide
|
C21H19N5O4
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0439440
|
N-[(3R)-6-(2-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C24H27FN6O3
|
2
|
| 1 |
IC50 = 150 nM
|
|
|
| 2 |
IC50 = 250 nM
|
|
|
|
CP0521190
|
2-[3-(3,5-difluorophenyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide
Show/Hide
|
C27H21F2N5O4
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0471397
|
N-[(3R,6S)-6-(3-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C24H27FN6O3
|
2
|
| 1 |
IC50 = 220 nM
|
|
|
| 2 |
IC50 = 250 nM
|
|
|
|
CP0485263
|
N-[(3R)-6-(3-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C24H27FN6O3
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0532115
|
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide
Show/Hide
|
C21H18N4O5
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0427920
|
4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-propan-2-ylazepan-3-yl]piperidine-1-carboxamide
Show/Hide
|
C21H30N6O3
|
2
|
| 1 |
IC50 = 380 nM
|
|
|
| 2 |
IC50 = 620 nM
|
|
|
|
CP0442412
|
N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(2-oxo-3-phenylbenzimidazol-1-yl)acetamide
Show/Hide
|
C26H21N5O4
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0439441
|
4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R,6S)-2-oxo-6-phenylazepan-3-yl]piperidine-1-carboxamide
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 520 nM
|
|
|
| 2 |
IC50 = 700 nM
|
|
|
|
CP0442414
|
N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(3-methyl-2-oxobenzimidazol-1-yl)acetamide
Show/Hide
|
C21H19N5O4
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0456866
|
N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(2-oxo-3H-benzimidazol-1-yl)acetamide
Show/Hide
|
C20H17N5O4
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0426942
|
4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-(3-thienyl)azepan-3-yl]piperidine-1-carboxamide
Show/Hide
|
C22H26N6O3S
|
2
|
| 1 |
IC50 = 750 nM
|
|
|
| 2 |
IC50 = 1800 nM
|
|
|
|
CP0485261
|
N-[(3R)-6-benzyl-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C25H30N6O3
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0463963
|
N-[(3R)-6-(4-hydroxyphenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Show/Hide
|
C24H28N6O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0377035
|
N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide
Show/Hide
|
C21H18N4O5
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0442279
|
N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide
Show/Hide
|
C20H16N4O5
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0514337
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N-(2',5'-dioxospiro[7,8-dihydro-5H-naphthalene-6,4'-imidazolidine]-2-yl)-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide
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C21H18N4O5
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1
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IC50 = 3300 nM
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