General Information of the Cell Line
Cell Line ID
CL000325
Cell Line Name
NCI-H2073
Synonyms
H2073
H-2073
NCIH2073
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1521
Tissue Information
Lung
Disease
Lung adenocarcinoma (NCIt: C3512)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00922, Epidermal growth factor receptor
Compound ID Compound Name Compound Formula
CP0033646
AZD-9291
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C28H33N7O2
 2
1
EC50 = 1865 nM
   TI
   LI
   LO
   TS
2
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0037987
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
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C22H23N3O4
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0543558
2-[4-(difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]phenyl]ethynyl]-7-methylindazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-N-(1,3-thiazol-2-yl)acetamide
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C37H37F2N7O2S
 1
1
IC50 = 545 nM
   TI
   LI
   LO
   TS
CP0534253
2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
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C29H26FN5O3S
 1
1
IC50 = 3910 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lung)
Cell Line Name Organism Disease
T84 Homo sapiens (Human) Colon adenocarcinoma
CFBE41o- Homo sapiens (Human) Cystic fibrosis
A-549 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1975 Homo sapiens (Human) Lung adenocarcinoma
HCC827 Homo sapiens (Human) Lung adenocarcinoma
NCI-H2228 Homo sapiens (Human) Lung adenocarcinoma
A-427 Homo sapiens (Human) Lung adenocarcinoma
HCC44 Homo sapiens (Human) Lung adenocarcinoma
HCC1171 Homo sapiens (Human) Lung adenocarcinoma
MR-5 Homo sapiens (Human) Lung adenocarcinoma
NCI-H522 Homo sapiens (Human) Lung adenocarcinoma
HCC366 Homo sapiens (Human) Lung adenosquamous carcinoma
NCI-H1581 Homo sapiens (Human) Lung large cell carcinoma
DMS 53 Homo sapiens (Human) Lung small cell carcinoma
NCI-H1417 Homo sapiens (Human) Lung small cell carcinoma
SW900 Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H520 Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1703 Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H2286 Homo sapiens (Human) Lung squamous cell carcinoma
Malme-3M Homo sapiens (Human) Melanoma
NCI-H358 Homo sapiens (Human) Minimally invasive lung adenocarcinoma
LLTC Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
LLTC Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
T8 Rattus norvegicus (Rat) Rat malignant mesothelioma
V79MZ Cricetulus griseus (Chinese hamster) -
V79 Cricetulus griseus (Chinese hamster) -
V79MZh11B2 Cricetulus griseus (Chinese hamster) -
V79MZh11B1 Cricetulus griseus (Chinese hamster) -
Dede Cricetulus griseus (Chinese hamster) -
39ER22 Cricetulus griseus (Chinese hamster) -
PS120 Cricetulus griseus (Chinese hamster) -
CHL Cricetulus griseus (Chinese hamster) -
NP1 Homo sapiens (Human) -
IMR-90 Homo sapiens (Human) -
Hs 888.Lu Homo sapiens (Human) -
BEAS-2B Homo sapiens (Human) -
WI-38 Homo sapiens (Human) -
HL Homo sapiens (Human) -
HFL1 Homo sapiens (Human) -
WI-38 VA13 subline 2RA Homo sapiens (Human) -
HBE1 Homo sapiens (Human) -
16HBE14o- Homo sapiens (Human) -
NAL1A clone C4E10 Mus musculus (Mouse) -
Mv1Lu Neovison vison (American mink) -
RFL-6 Rattus norvegicus (Rat) -
PAC1 Rattus norvegicus (Rat) -
RLE Rattus norvegicus (Rat) -