General Information of the Cell Line
Cell Line ID
CL000612
Cell Line Name
BEAS-2B
Synonyms
Beas-2B
BEAS 2B
BEAS2B
Beas2B
Bronchial Epithelium transformed with Ad12-SV40 2B
Category
Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0168
Tissue Information
Lung
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01494, Beta-2 adrenergic receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0455898
 Compound Info 
5-[(1R)-2-[2-[4-[3-[3-(aminomethyl)phenyl]-4-methoxyanilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C33H34N4O4
  1
1
EC50 = 0.3162 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0169525
 Compound Info 
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-(4-methoxy-3-phenylanilino)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C32H31N3O4
  1
1
EC50 = 0.3981 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0065062
 Compound Info 
1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol
   Show/Hide
C25H37NO4
  1
1
EC50 = 0.5012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0308646
 Compound Info 
MILVETEROL
   Show/Hide
C25H29N3O4
  1
1
EC50 = 0.5012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419570
 Compound Info 
5-[(1R)-2-[2-[4-[3-[4-(aminomethyl)phenyl]-4-methoxyanilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C33H34N4O4
  1
1
EC50 = 0.5012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0455897
 Compound Info 
5-[(1R)-2-[2-[4-[4-(2-aminoethoxy)anilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C27H30N4O4
  1
1
EC50 = 0.5012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0411222
 Compound Info 
5-[(1R)-2-[2-[4-[4-[2-(2-aminoethoxy)ethoxy]anilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C29H34N4O5
  1
1
EC50 = 0.631 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419603
 Compound Info 
5-[(1R)-2-[2-[4-[4-(3-aminopropoxy)anilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C28H32N4O4
  1
1
EC50 = 0.631 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0455896
 Compound Info 
5-[(1R)-2-[2-[4-[4-(2-amino-2-methylpropoxy)-3-phenylanilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C35H38N4O4
  1
1
EC50 = 0.631 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0455899
 Compound Info 
5-[(1R)-2-[2-[4-[4-(4-aminobutoxy)anilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C29H34N4O4
  1
1
EC50 = 0.631 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475960
 Compound Info 
5-[(1R)-2-[2-[4-[3-[2-(aminomethyl)phenyl]-4-methoxyanilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C33H34N4O4
  1
1
EC50 = 0.7943 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399516
 Compound Info 
5-[(1R)-2-[2-[4-[4-(2-amino-2-methylpropoxy)anilino]phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C29H34N4O4
  1
1
EC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391352
 Compound Info 
4-[(1R)-1-hydroxy-2-[2-[4-[[(2R)-2-hydroxy-2-phenylethyl]amino]phenyl]ethylamino]ethyl]-2-(hydroxymethyl)phenol
   Show/Hide
C25H30N2O4
  1
1
EC50 = 1.259 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392811
 Compound Info 
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[[(2R)-2-hydroxy-2-phenylethyl]amino]phenyl]ethylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C27H29N3O4
  1
1
EC50 = 1.259 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463392
 Compound Info 
N-[2-[4-[4-[2-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]anilino]phenoxy]ethyl]benzamide
   Show/Hide
C34H34N4O5
  1
1
EC50 = 1.585 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0480334
 Compound Info 
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[4-(2-piperazin-1-ylethoxy)anilino]phenyl]ethylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C31H37N5O4
  1
1
EC50 = 1.585 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0414197
 Compound Info 
5-[(1R)-2-[2-[4-(4-ethoxyanilino)phenyl]ethylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
   Show/Hide
C27H29N3O4
  1
1
EC50 = 1.995 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0066323
 Compound Info 
CAS_73573-87-2
   Show/Hide
C19H24N2O4
  1
1
EC50 = 2.512 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419548
 Compound Info 
tert-butyl N-[2-[4-[4-[2-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]anilino]phenoxy]ethyl]carbamate
   Show/Hide
C32H38N4O6
  1
1
EC50 = 2.512 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399515
 Compound Info 
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[4-(2-morpholin-4-ylethoxy)anilino]phenyl]ethylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C31H36N4O5
  1
1
EC50 = 3.162 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0414195
 Compound Info 
N-[5-[(1R)-2-[2-[4-[4-(2-amino-2-methylpropoxy)anilino]phenyl]ethylamino]-1-hydroxyethyl]-2-hydroxyphenyl]formamide
   Show/Hide
C27H34N4O4
  1
1
EC50 = 3.162 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0405887
 Compound Info 
4-[(1R)-1-hydroxy-2-[2-[4-[[(2S)-2-hydroxy-2-phenylethyl]amino]phenyl]ethylamino]ethyl]-2-(hydroxymethyl)phenol
   Show/Hide
C25H30N2O4
  1
1
EC50 = 3.981 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0378652
 Compound Info 
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[4-[2-(4-methylsulfonylpiperazin-1-yl)ethoxy]anilino]phenyl]ethylamino]ethyl]-1H-quinolin-2-one
   Show/Hide
C32H39N5O6S
  1
1
EC50 = 6.31 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT02183, Capsaicin receptor
 Protein Info 
Protein ID: PT04367, Nuclear factor erythroid 2-related factor 2
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0437693
 Compound Info 
4-fluoro-N-[(E)-1-[4-[4-[(E)-N-(4-fluoroanilino)-C-methylcarbonimidoyl]phenyl]phenyl]ethylideneamino]aniline
   Show/Hide
 C28H24F2N4  1
1
CC50 = 23541.31831 nM
   TI
   LI
   LO
   TS
CP0474168
 Compound Info 
4-fluoro-N-[(E)-[4-[3-[(E)-[(4-fluorophenyl)hydrazinylidene]methyl]phenyl]phenyl]methylideneamino]aniline
   Show/Hide
 C26H20F2N4  1
1
CC50 > 72689.75543 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lung)
Cell Line Name Organism Disease
T84
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
CFBE41o-
 Cell Line Info 
Homo sapiens (Human) Cystic fibrosis
A-549
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1975
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2073
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC827
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2228
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
A-427
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC44
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC1171
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
MR-5
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H522
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC366
 Cell Line Info 
Homo sapiens (Human) Lung adenosquamous carcinoma
NCI-H1581
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
DMS 53
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H1417
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
SW900
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H520
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1703
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H2286
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
Malme-3M
 Cell Line Info 
Homo sapiens (Human) Melanoma
NCI-H358
 Cell Line Info 
Homo sapiens (Human) Minimally invasive lung adenocarcinoma
LLTC
 Cell Line Info 
Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
LLTC
 Cell Line Info 
Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
T8
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant mesothelioma
V79MZ
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
V79
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
V79MZh11B2
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
V79MZh11B1
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
Dede
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
39ER22
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
PS120
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
CHL
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
NP1
 Cell Line Info 
Homo sapiens (Human) -
IMR-90
 Cell Line Info 
Homo sapiens (Human) -
Hs 888.Lu
 Cell Line Info 
Homo sapiens (Human) -
WI-38
 Cell Line Info 
Homo sapiens (Human) -
HL
 Cell Line Info 
Homo sapiens (Human) -
HFL1
 Cell Line Info 
Homo sapiens (Human) -
WI-38 VA13 subline 2RA
 Cell Line Info 
Homo sapiens (Human) -
HBE1
 Cell Line Info 
Homo sapiens (Human) -
16HBE14o-
 Cell Line Info 
Homo sapiens (Human) -
NAL1A clone C4E10
 Cell Line Info 
Mus musculus (Mouse) -
Mv1Lu
 Cell Line Info 
Neovison vison (American mink) -
RFL-6
 Cell Line Info 
Rattus norvegicus (Rat) -
PAC1
 Cell Line Info 
Rattus norvegicus (Rat) -
RLE
 Cell Line Info 
Rattus norvegicus (Rat) -