2-[5-(4-chloro-7-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

2-[5-(4,7-difluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile

2-[5-(7-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

2-methyl-1,2-dipyridin-3-ylpropan-1-one

1-cyclopropyl-2-(4,5-dimethylpyridin-3-yl)-5,6-difluorobenzimidazole

(R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile

2-[5-(4-fluoro-3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol

4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile

2-[5-(3-chloro-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol

2-[5-(6-fluoro-3-methylimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol

2-(5-(1-cyclopropyl-5,6-difluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)propan-2-ol

1,1,1-trifluoro-2-[5-(5-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

4-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)-3-methylbenzonitrile

2-[5-[4-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol

4-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)isoquinoline

2-(5-(1-cyclopropyl-6-fluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)propan-2-ol

4-[(5R)-5-methoxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile

2-[[(5R)-3-(4-cyano-2-methylphenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-5-yl]oxy]pyrimidine-5-carbonitrile

3-methyl-4-[(5R)-5-phenylmethoxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile

3-cyclopropyl-6-fluoro-2-pyridin-3-ylbenzimidazole-5-carbonitrile

3-methyl-4-[(5R)-5-pyrazin-2-yloxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile

2-[5-(4-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

3-methyl-4-[(5R)-5-(5-methylpyrimidin-2-yl)oxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile

2-[5-(5-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

2-[5-(4-methylindazol-1-yl)pyridin-3-yl]propan-2-ol

7-[5-(2-methoxypropan-2-yl)pyridin-3-yl]-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

3-cyclopropyl-2-[5-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridin-3-yl]imidazo[1,2-a]pyridine-6-carbonitrile

US8987315, Ketoconazole

3-cyclopropyl-6-fluoro-2-(5-fluoropyridin-3-yl)benzimidazole-5-carbonitrile

1-cyclopropyl-5,6-difluoro-2-(5-methoxypyridin-3-yl)benzimidazole

(2R)-2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol

6-chloro-1-cyclopropyl-5-fluoro-2-(5-fluoropyridin-3-yl)benzimidazole

1-cyclopropyl-5,6-difluoro-2-(5-fluoro-4-methylpyridin-3-yl)benzimidazole

3-cyclopropyl-6-fluoro-2-(5-methylpyridin-3-yl)imidazo[1,2-a]pyridine

US9351973, 7

3-[(Z)-2-Phenylvinyl]pyridine

3-cyclopropyl-6-fluoro-2-(5-phenylpyridin-3-yl)imidazo[1,2-a]pyridine

methyl 2-methyl-2-[5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]propanoate

6-chloro-1-cyclopropyl-5-fluoro-2-pyridin-3-ylbenzimidazole

(2S)-1,1,1-trifluoro-2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol

4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-3-methylbenzonitrile

(2S)-1,1,1-trifluoro-2-[5-(2-oxa-8-azaspiro[4.5]decan-8-yl)pyridin-3-yl]propan-2-ol

1-cyclopropyl-5,6-difluoro-2-pyridin-3-ylbenzimidazole

3-cyclopropyl-2-pyridin-3-ylbenzimidazole-5-carbonitrile

(2R)-1,1,1-trifluoro-2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol

8-isoquinolin-4-yl-2-oxa-8-azaspiro[4.5]decane

1-cyclopropyl-6-fluoro-2-pyridin-3-ylbenzimidazole

7-isoquinolin-4-yl-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

2-[[(5R)-3-(4-cyano-2-methylphenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-5-yl]oxy]acetamide

1-cyclopropyl-5,6-difluoro-2-(5-fluoropyridin-3-yl)benzimidazole

1-cyclopropyl-5,6-difluoro-2-(4-methoxy-5-methylpyridin-3-yl)benzimidazole

(2S)-2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol

2-[5-(5-chloroindazol-1-yl)pyridin-3-yl]propan-2-ol

3-methyl-4-[(5R)-5-pyrimidin-2-yloxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile

6-chloro-1-cyclopropyl-2-pyridin-3-ylbenzimidazole

3-chloro-4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzonitrile

N-[[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]methyl]ethanesulfonamide

3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine

methyl 5-(5-fluoroindazol-1-yl)pyridine-3-carboxylate

3-cyclopropyl-6-fluoro-2-(5-methoxypyridin-3-yl)imidazo[1,2-a]pyridine

2-(5-indazol-1-ylpyridin-3-yl)propan-2-ol

3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine

3-cyclopropyl-6-fluoro-2-[5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridine

4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-methylbenzonitrile

6-fluoro-2-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]imidazo[1,2-a]pyridine-3-carbonitrile

(2S)-2-[5-(3-cyclopropyl-7-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol

1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole

methyl 5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridine-3-carboxylate

6-fluoro-1-methyl-2-pyridin-3-ylbenzimidazole

1-cyclopropyl-5,6-difluoro-2-(4-methylpyridin-3-yl)benzimidazole

6-chloro-3-cyclopropyl-7-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine

1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidazole

2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol

8-isoquinolin-4-yl-1-oxa-8-azaspiro[4.5]decane

1-cyclopropyl-5,6-difluoro-2-[4-(trifluoromethyl)pyridin-3-yl]benzimidazole

3-cyclopropyl-2-(4-ethyl-5-fluoropyridin-3-yl)-6-fluoroimidazo[1,2-a]pyridine

2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol

(2S)-1,1,1-trifluoro-2-[5-[3-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol

2-[5-(6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol

(2S)-1,1,1-trifluoro-2-[5-[1-(trifluoromethyl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl]pyridin-3-yl]propan-2-ol

2-[5-(5-methylindazol-1-yl)pyridin-3-yl]propan-2-ol

3-cyclopropyl-6-fluoro-2-(5-fluoro-4-methylpyridin-3-yl)imidazo[1,2-a]pyridine

1-(8-isoquinolin-4-yl-2,8-diazaspiro[4.5]decan-2-yl)ethanone

2-[5-(5-methoxyindazol-1-yl)pyridin-3-yl]propan-2-ol

US9351973, 26

6-chloro-3-cyclopropyl-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine

4-[(5R)-5-(5-fluoropyrimidin-2-yl)oxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile

2-[5-[5-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol

4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-3-fluorobenzonitrile

3-(1-Methyl-3,4-dihydronaphthalen-2-yl)-pyridine

3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine

5-fluoro-1-(5-methoxypyridin-3-yl)indazole

8-isoquinolin-4-yl-2,8-diazaspiro[4.5]decane

US9351973, 13

1-phenyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

2-[5-(3-methoxyindazol-1-yl)pyridin-3-yl]propan-2-ol

2-[5-[1-(trifluoromethyl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl]pyridin-3-yl]propan-2-ol

7-[5-(benzenesulfonyl)pyridin-3-yl]-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

2-methyl-8-[5-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridin-3-yl]-2,8-diazaspiro[4.5]decan-3-one

5-(1-cyclopropyl-5,6-difluorobenzimidazol-2-yl)pyridine-3-carbonitrile

3-isoquinolin-4-yl-3-azaspiro[5.5]undecane

7-isoquinolin-4-yl-2-oxa-7-azaspiro[3.5]nonane

3-(4-Ethyl-3,4-dihydronaphthalen-2-yl)pyridine

4-(8-azaspiro[4.5]decan-8-yl)isoquinoline

5-fluoro-1-[5-(trifluoromethyl)pyridin-3-yl]indazole

3-(3,4-Dihydronaphthalen-2-yl)pyridine

8-[6-(3,3-dimethylazetidin-1-yl)pyrazin-2-yl]-2,8-diazaspiro[4.5]decan-3-one

3-cyclopropyl-6-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine

US9351973, 12

1-cyclopropyl-2-pyridin-3-yl-6-(trifluoromethyl)benzimidazole

4-[(5R)-5-hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile

1-cyclopropyl-6-methoxy-2-pyridin-3-ylbenzimidazole

6-fluoro-2-pyridin-3-yl-1H-benzimidazole

2-[5-(6-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol

8-isoquinolin-4-yl-2-methyl-2,8-diazaspiro[4.5]decan-3-one

4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-fluorobenzonitrile

1-ethyl-6-fluoro-2-pyridin-3-ylbenzimidazole

3-(1-Ethyl-3,4-dihydronaphthalen-2-yl)-pyridine

8-[6-(3,3-dimethylazetidin-1-yl)pyrazin-2-yl]-1,8-diazaspiro[4.5]decan-2-one

methyl 5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridine-3-carboxylate

4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-3-methoxybenzonitrile

US9351973, 9

3-(1H-Inden-2-yl)pyridine

4-[(5S)-5-hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile

4-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine

6-fluoro-1-(1-methylcyclopropyl)-2-(pyridin-3-yl)-1H-benzo[d]imidazole

US9351973, 15

US9351973, 8

6-fluoro-1-propan-2-yl-2-pyridin-3-ylbenzimidazole

1-cyclopropyl-5-fluoro-2-pyridin-3-ylbenzimidazole

(2S)-1,1,1-trifluoro-2-[5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]propan-2-ol

8-[6-(3,3-dimethylazetidin-1-yl)pyrazin-2-yl]-2-methyl-2,8-diazaspiro[4.5]decan-3-one

3-cyclopropyl-7-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine

3-(5-Methoxy-1H-inden-2-yl)pyridine

4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzonitrile

3,4-Difluoro-N-(pyridin-3-yl)benzamide

4-Cyano-N-(pyridin-3-yl)benzamide

1-cyclopropyl-2-pyridin-3-yl-5-(trifluoromethyl)benzimidazole

1-cyclobutyl-6-fluoro-2-pyridin-3-ylbenzimidazole

1-cyclopropyl-5-methylsulfonyl-2-pyridin-3-ylbenzimidazole

1-tert-butyl-6-fluoro-2-pyridin-3-ylbenzimidazole

1-cyclopropyl-2-pyridin-3-ylbenzimidazole-5-carbonitrile

1-cyclopropyl-7-fluoro-2-pyridin-3-ylbenzimidazole

1-cyclopropyl-5-methoxy-2-pyridin-3-ylbenzimidazole

1-methyl-7-[5-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

1-cyclopropyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

7-(5-fluoropyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

1-methyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline

2-methyl-8-[5-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridin-3-yl]-2,8-diazaspiro[4.5]decan-3-one

4-[(5S)-5-(5-fluoropyrimidin-2-yl)oxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile

4-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]benzonitrile

4-(5-ethyl-1-methylpyrazol-4-yl)benzonitrile

4-(1,5-dimethylpyrazol-4-yl)benzonitrile

4-(1-ethyl-5-methylpyrazol-4-yl)benzonitrile

4-[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]benzonitrile

4-Chloro-N-(pyridin-3-yl)benzamide

4-Fluoro-N-(pyridin-3-yl)benzamide

2,4,5-trifluoro-N-(pyridin-3-yl)benzamide

4-Bromo-N-(pyridin-3-yl)benzamide

4-Nitro-N-(pyridin-3-yl)benzamide

8-isoquinolin-4-yl-2-methyl-2,8-diazaspiro[4.5]decan-1-one

tert-butyl 8-isoquinolin-4-yl-2,8-diazaspiro[4.5]decane-2-carboxylate

2-[5-(3-cyclopropylindazol-1-yl)pyridin-3-yl]propan-2-ol

5-fluoro-1-(5-fluoropyridin-3-yl)indazole

5-fluoro-1-pyridin-3-ylindazole

2-[5-[3-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol

2-[5-(6-chloroindazol-1-yl)pyridin-3-yl]propan-2-ol

2-[5-[6-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol

1-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]indazole-5-carbonitrile