| Compound ID |
Compound Name |
Compound Formula |
|
CP0406118
|
1-cyclopropyl-2-(4,5-dimethylpyridin-3-yl)-5,6-difluorobenzimidazole
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|
C17H15F2N3
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0509488
|
2-[5-(4-chloro-7-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H13ClFN3O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0667085
|
2-(5-(1-cyclopropyl-5,6-difluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)propan-2-ol
Show/Hide
|
C18H17F2N3O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0475959
|
2-[5-(4,7-difluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H13F2N3O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0388876
|
6-chloro-1-cyclopropyl-5-fluoro-2-pyridin-3-ylbenzimidazole
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|
C15H11ClFN3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0491366
|
1-cyclopropyl-5,6-difluoro-2-(5-methoxypyridin-3-yl)benzimidazole
Show/Hide
|
C16H13F2N3O
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0401274
|
1-cyclopropyl-5,6-difluoro-2-(5-fluoro-4-methylpyridin-3-yl)benzimidazole
Show/Hide
|
C16H12F3N3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0385481
|
3-cyclopropyl-6-fluoro-2-pyridin-3-ylbenzimidazole-5-carbonitrile
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|
C16H11FN4
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0433701
|
1-cyclopropyl-5,6-difluoro-2-(4-methoxy-5-methylpyridin-3-yl)benzimidazole
Show/Hide
|
C17H15F2N3O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0091722
|
4-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)isoquinoline
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|
C19H14FN3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0488258
|
6-chloro-1-cyclopropyl-5-fluoro-2-(5-fluoropyridin-3-yl)benzimidazole
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|
C15H10ClF2N3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0402840
|
2-[5-(7-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14FN3O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0116773
|
4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0401276
|
3-cyclopropyl-6-fluoro-2-(5-fluoropyridin-3-yl)benzimidazole-5-carbonitrile
Show/Hide
|
C16H10F2N4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0420139
|
3-cyclopropyl-2-pyridin-3-ylbenzimidazole-5-carbonitrile
Show/Hide
|
C16H12N4
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0388600
|
2-[5-(3-chloro-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H13ClFN3O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0447461
|
2-[5-(6-fluoro-3-methylimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H16FN3O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0134578
|
4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
Show/Hide
|
C13H10FN3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0201912
|
2-[5-(4-fluoro-3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H16FN3O
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0643522
|
2-(5-(1-cyclopropyl-6-fluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)propan-2-ol
Show/Hide
|
C18H18FN3O
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 2.3 nM
|
|
|
|
CP0435098
|
3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine
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|
C16H15NO
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0475958
|
1,1,1-trifluoro-2-[5-(5-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H11F4N3O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0388877
|
1-cyclopropyl-5,6-difluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H11F2N3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0388843
|
6-chloro-1-cyclopropyl-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H12ClN3
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0483346
|
US9351973, 7
Show/Hide
|
C13H14N4O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0180854
|
2-[5-[4-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0446790
|
3-methyl-4-[(5R)-5-pyrazin-2-yloxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile
Show/Hide
|
C18H15N5O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0519950
|
2-[[(5R)-3-(4-cyano-2-methylphenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-5-yl]oxy]pyrimidine-5-carbonitrile
Show/Hide
|
C19H14N6O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0564047
|
3-methyl-4-[(5R)-5-phenylmethoxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile
Show/Hide
|
C21H19N3O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0414400
|
methyl 5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridine-3-carboxylate
Show/Hide
|
C17H14FN3O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0476346
|
4-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)-3-methylbenzonitrile
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0396420
|
4-[(5R)-5-methoxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile
Show/Hide
|
C15H15N3O
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0511806
|
3-cyclopropyl-6-fluoro-2-(5-methylpyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C16H14FN3
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0408851
|
4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-3-methylbenzonitrile
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0037815
|
3-(5-Methoxy-1H-inden-2-yl)pyridine
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|
C15H13NO
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0446856
|
1-cyclopropyl-6-fluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0451466
|
3-cyclopropyl-6-fluoro-2-(5-methoxypyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C16H14FN3O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0476344
|
3-methyl-4-[(5R)-5-pyrimidin-2-yloxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile
Show/Hide
|
C18H15N5O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0465192
|
3-methyl-4-[(5R)-5-(5-methylpyrimidin-2-yl)oxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzonitrile
Show/Hide
|
C19H17N5O
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0133117
|
1-cyclopropyl-5,6-difluoro-2-(5-fluoropyridin-3-yl)benzimidazole
Show/Hide
|
C15H10F3N3
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0380764
|
(2R)-2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C18H15F4N3O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0408852
|
4-[(5R)-5-(5-fluoropyrimidin-2-yl)oxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile
Show/Hide
|
C18H14FN5O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0442774
|
3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C16H15N
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0434020
|
7-isoquinolin-4-yl-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H16N4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0478375
|
3-chloro-4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzonitrile
Show/Hide
|
C13H10ClN3
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0414401
|
3-cyclopropyl-2-[5-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridin-3-yl]imidazo[1,2-a]pyridine-6-carbonitrile
Show/Hide
|
C19H15F3N4O
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0327042
|
(R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0048211
|
3-cyclopropyl-2-(4-ethyl-5-fluoropyridin-3-yl)-6-fluoroimidazo[1,2-a]pyridine
Show/Hide
|
C17H15F2N3
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0294276
|
(2S)-2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C18H15F4N3O
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0399595
|
3-cyclopropyl-6-fluoro-2-(5-phenylpyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C21H16FN3
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0446789
|
4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-methylbenzonitrile
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0419098
|
3-(3,4-Dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C15H13N
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0424724
|
3-(1-Methyl-3,4-dihydronaphthalen-2-yl)-pyridine
Show/Hide
|
C16H15N
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0091723
|
6-chloro-3-cyclopropyl-7-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C15H10ClF2N3
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0571867
|
2-[5-(4-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14FN3O
|
1
|
| 1 |
IC50 = 7.58 nM
|
|
|
|
CP0402845
|
2-[5-(4-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
IC50 = 7.77 nM
|
|
|
|
CP0489625
|
US9351973, 9
Show/Hide
|
C15H18N4O
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0190104
|
3-cyclopropyl-6-fluoro-2-(5-fluoro-4-methylpyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C16H13F2N3
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0550039
|
1-cyclopropyl-5,6-difluoro-2-[4-(trifluoromethyl)pyridin-3-yl]benzimidazole
Show/Hide
|
C16H10F5N3
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0446787
|
4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-3-fluorobenzonitrile
Show/Hide
|
C13H10FN3
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0479753
|
US9351973, 8
Show/Hide
|
C14H16N4O
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
|
CP0399597
|
3-cyclopropyl-6-fluoro-2-[5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridine
Show/Hide
|
C16H11F4N3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0388844
|
1-cyclopropyl-5,6-difluoro-2-(4-methylpyridin-3-yl)benzimidazole
Show/Hide
|
C16H13F2N3
|
1
|
| 1 |
IC50 = 10.2 nM
|
|
|
|
CP0447032
|
2-[5-(5-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14FN3O
|
1
|
| 1 |
IC50 = 10.9 nM
|
|
|
|
CP0489607
|
US9351973, 13
Show/Hide
|
C13H13FN4O
|
1
|
| 1 |
IC50 = 11.7 nM
|
|
|
|
CP0559354
|
6-fluoro-1-methyl-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C13H10FN3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0558992
|
4-[(5R)-5-hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0382469
|
3-(1H-Inden-2-yl)pyridine
Show/Hide
|
C14H11N
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0414538
|
3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C16H15N
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0446136
|
(2S)-1,1,1-trifluoro-2-[5-(2-oxa-8-azaspiro[4.5]decan-8-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H21F3N2O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0468079
|
8-isoquinolin-4-yl-2-oxa-8-azaspiro[4.5]decane
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0388599
|
2-[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C18H18FN3O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0446786
|
4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzonitrile
Show/Hide
|
C13H11N3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0540011
|
US9351973, 10
Show/Hide
|
C15H16N4O
|
1
|
| 1 |
IC50 = 13.2 nM
|
|
|
|
CP0244010
|
(2S)-1,1,1-trifluoro-2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0476343
|
2-[[(5R)-3-(4-cyano-2-methylphenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-5-yl]oxy]acetamide
Show/Hide
|
C16H16N4O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0447034
|
2-(5-indazol-1-ylpyridin-3-yl)propan-2-ol
Show/Hide
|
C15H15N3O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0950636
|
6-fluoro-1-(1-methylcyclopropyl)-2-(pyridin-3-yl)-1H-benzo[d]imidazole
Show/Hide
|
C16H14FN3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0040950
|
7-[5-(2-methoxypropan-2-yl)pyridin-3-yl]-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0456372
|
methyl 2-methyl-2-[5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]propanoate
Show/Hide
|
C21H22N4O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0540012
|
US9351973, 12
Show/Hide
|
C13H13FN4O
|
1
|
| 1 |
IC50 = 19.1 nM
|
|
|
|
CP0402846
|
methyl 1-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]indazole-4-carboxylate
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0491365
|
5-(1-cyclopropyl-5,6-difluorobenzimidazol-2-yl)pyridine-3-carbonitrile
Show/Hide
|
C16H10F2N4
|
1
|
| 1 |
IC50 = 22.3 nM
|
|
|
|
CP0504436
|
6-chloro-3-cyclopropyl-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C15H11ClFN3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0517632
|
6-fluoro-2-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]imidazo[1,2-a]pyridine-3-carbonitrile
Show/Hide
|
C16H13FN4O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0510929
|
1-cyclopropyl-6-methoxy-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0190103
|
3-cyclopropyl-6-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C15H11F2N3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0477708
|
2-[5-(3-methoxyindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H17N3O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0447463
|
(2S)-2-[5-(3-cyclopropyl-7-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C18H15F4N3O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0476345
|
4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-fluorobenzonitrile
Show/Hide
|
C13H10FN3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0458508
|
2-[5-(5-chloroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14ClN3O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0555773
|
1-cyclopropyl-5-fluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0519948
|
4-[(5S)-5-hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0479649
|
3-(1-Ethyl-3,4-dihydronaphthalen-2-yl)-pyridine
Show/Hide
|
C17H17N
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0499608
|
US9351973, 15
Show/Hide
|
C12H11FN4O
|
1
|
| 1 |
IC50 = 30.9 nM
|
|
|
|
CP0419782
|
methyl 5-(5-fluoroindazol-1-yl)pyridine-3-carboxylate
Show/Hide
|
C14H10FN3O2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0432224
|
2-methyl-8-[5-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridin-3-yl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C17H22F3N3O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0108244
|
(2R)-1,1,1-trifluoro-2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
IC50 = 32.9 nM
|
|
|
|
CP0447462
|
N-[[5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]methyl]ethanesulfonamide
Show/Hide
|
C18H19FN4O2S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0447033
|
2-[5-(3-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
IC50 = 33.5 nM
|
|
|
|
CP0408912
|
8-[6-(3,3-dimethylazetidin-1-yl)pyrazin-2-yl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C17H25N5O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0465189
|
4-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-3-methoxybenzonitrile
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0388881
|
1-ethyl-6-fluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C14H12FN3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0442674
|
7-[5-(benzenesulfonyl)pyridin-3-yl]-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C22H18N4O2S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0373986
|
(S)Fadrozole
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0414314
|
7-isoquinolin-4-yl-2-oxa-7-azaspiro[3.5]nonane
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0419784
|
5-fluoro-1-(5-methoxypyridin-3-yl)indazole
Show/Hide
|
C13H10FN3O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0408906
|
3-(7-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C16H15NO
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0388879
|
1-cyclopropyl-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H13N3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0399594
|
2-[5-(6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14FN3O
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0402948
|
3,4-Difluoro-N-(pyridin-3-yl)benzamide
Show/Hide
|
C12H8F2N2O
|
1
|
| 1 |
IC50 = 53.5 nM
|
|
|
|
CP0252415
|
methyl 5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridine-3-carboxylate
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0065022
|
(2S)-1,1,1-trifluoro-2-[5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C19H17F3N4O
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0371718
|
4-Chloro-N-(pyridin-3-yl)benzamide
Show/Hide
|
C12H9ClN2O
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0446788
|
4-[(5S)-5-(5-fluoropyrimidin-2-yl)oxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-3-methylbenzonitrile
Show/Hide
|
C18H14FN5O
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0085966
|
2-methyl-1,2-dipyridin-3-ylpropan-1-one
Show/Hide
|
C14H14N2O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0519949
|
4-(1-ethyl-5-methylpyrazol-4-yl)benzonitrile
Show/Hide
|
C13H13N3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0414313
|
8-[6-(3,3-dimethylazetidin-1-yl)pyrazin-2-yl]-1,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C17H25N5O
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0240397
|
(2S)-1,1,1-trifluoro-2-[5-[3-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H11F6N3O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0436966
|
4-Cyano-N-(pyridin-3-yl)benzamide
Show/Hide
|
C13H9N3O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0471098
|
2-[5-(6-fluoroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14FN3O
|
1
|
| 1 |
IC50 = 78.5 nM
|
|
|
|
CP0005212
|
US8987315, Ketoconazole
Show/Hide
|
C26H28Cl2N4O4
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0427421
|
4-Fluoro-N-(pyridin-3-yl)benzamide
Show/Hide
|
C12H9FN2O
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0492026
|
2-[5-(5-methoxyindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H17N3O2
|
1
|
| 1 |
IC50 = 84.9 nM
|
|
|
|
CP0475957
|
5-fluoro-1-[5-(trifluoromethyl)pyridin-3-yl]indazole
Show/Hide
|
C13H7F4N3
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0466947
|
8-[6-(3,3-dimethylazetidin-1-yl)pyrazin-2-yl]-2-methyl-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C18H27N5O
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0458509
|
2-[5-(5-methylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
IC50 = 97.9 nM
|
|
|
|
CP0414402
|
3-cyclopropyl-7-fluoro-2-(5-fluoropyridin-3-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C15H11F2N3
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0489608
|
US9351973, 19
Show/Hide
|
C14H13FN4O
|
1
|
| 1 |
IC50 = 102.3 nM
|
|
|
|
CP0369408
|
1-phenyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C21H16N4
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0475953
|
4-Bromo-N-(pyridin-3-yl)benzamide
Show/Hide
|
C12H9BrN2O
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0414307
|
4-(8-azaspiro[4.5]decan-8-yl)isoquinoline
Show/Hide
|
C18H22N2
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0542682
|
1-cyclopropyl-7-fluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0041555
|
(2R)-1,1,1-trifluoro-2-[5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C19H17F3N4O
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0433702
|
6-fluoro-1-propan-2-yl-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H14FN3
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0470507
|
4-Nitro-N-(pyridin-3-yl)benzamide
Show/Hide
|
C12H9N3O3
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0465190
|
4-(5-ethyl-1-methylpyrazol-4-yl)benzonitrile
Show/Hide
|
C13H13N3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0399596
|
5-(3-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-2-yl)pyridine-3-carbonitrile
Show/Hide
|
C16H11FN4
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0505162
|
2,4,5-trifluoro-N-(pyridin-3-yl)benzamide
Show/Hide
|
C12H7F3N2O
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0424723
|
3-(4-Ethyl-3,4-dihydronaphthalen-2-yl)pyridine
Show/Hide
|
C17H17N
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0457616
|
5-fluoro-1-pyridin-3-ylindazole
Show/Hide
|
C12H8FN3
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0446852
|
1-cyclopropyl-4-fluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C15H12FN3
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0414310
|
8-isoquinolin-4-yl-2-methyl-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
IC50 = 228 nM
|
|
|
|
CP0388878
|
1-cyclopropyl-2-pyridin-3-yl-6-(trifluoromethyl)benzimidazole
Show/Hide
|
C16H12F3N3
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
|
CP0558625
|
4-[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]benzonitrile
Show/Hide
|
C12H8F3N3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0380088
|
2-[5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
|
CP0483126
|
4-(1,5-dimethylpyrazol-4-yl)benzonitrile
Show/Hide
|
C12H11N3
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0442676
|
7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C15H12N4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0464086
|
2-[5-[3-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0441767
|
1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole
Show/Hide
|
C13H12N2
|
1
|
| 1 |
IC50 = 334 nM
|
|
|
|
CP0376604
|
1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidazole
Show/Hide
|
C14H14N2O
|
1
|
| 1 |
IC50 = 411 nM
|
|
|
|
CP0442677
|
1-methyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H14N4
|
1
|
| 1 |
IC50 = 423 nM
|
|
|
|
CP0382470
|
1-(1H-Inden-2-yl)-1H-imidazole
Show/Hide
|
C12H10N2
|
1
|
| 1 |
IC50 = 448 nM
|
|
|
|
CP0414317
|
2-methyl-8-[5-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]pyridin-3-yl]-2,8-diazaspiro[4.5]decan-3-one
Show/Hide
|
C17H22F3N3O2
|
1
|
| 1 |
IC50 = 448 nM
|
|
|
|
CP0407238
|
5-fluoro-1-(5-fluoropyridin-3-yl)indazole
Show/Hide
|
C12H7F2N3
|
1
|
| 1 |
IC50 = 456 nM
|
|
|
|
CP0456373
|
(2S)-1,1,1-trifluoro-2-[5-[1-(trifluoromethyl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C19H14F6N4O
|
1
|
| 1 |
IC50 = 461 nM
|
|
|
|
CP0409886
|
(2R)-1,1,1-trifluoro-2-[5-[1-(trifluoromethyl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C19H14F6N4O
|
1
|
| 1 |
IC50 = 476 nM
|
|
|
|
CP0380167
|
1-methyl-7-[5-(trifluoromethyl)pyridin-3-yl]-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C17H13F3N4
|
1
|
| 1 |
IC50 = 486 nM
|
|
|
|
CP0384853
|
1-cyclopropyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C18H16N4
|
1
|
| 1 |
IC50 = 487 nM
|
|
|
|
CP0388133
|
7-pyridin-3-yl-1-(trifluoromethyl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H11F3N4
|
1
|
| 1 |
IC50 = 506 nM
|
|
|
|
CP0509487
|
2-[5-[5-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
IC50 = 507 nM
|
|
|
|
CP0384866
|
2-[5-[1-(trifluoromethyl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl]pyridin-3-yl]propan-2-ol
Show/Hide
|
C19H17F3N4O
|
1
|
| 1 |
IC50 = 526 nM
|
|
|
|
CP0475956
|
2-[5-(6-chloroindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C15H14ClN3O
|
1
|
| 1 |
IC50 = 528 nM
|
|
|
|
CP0414308
|
3-isoquinolin-4-yl-3-azaspiro[5.5]undecane
Show/Hide
|
C19H24N2
|
1
|
| 1 |
IC50 = 554 nM
|
|
|
|
CP0414126
|
7-(5-fluoropyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
IC50 = 558 nM
|
|
|
|
CP0457602
|
6-fluoro-2-pyridin-3-yl-1-(2,2,2-trifluoroethyl)benzimidazole
Show/Hide
|
C14H9F4N3
|
1
|
| 1 |
IC50 = 561 nM
|
|
|
|
CP0412841
|
1-benzyl-6-fluoro-2-pyridin-3-ylbenzimidazole
Show/Hide
|
C19H14FN3
|
1
|
| 1 |
IC50 = 607 nM
|
|
|
|
CP0572543
|
8-isoquinolin-4-yl-1-oxa-8-azaspiro[4.5]decane
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
IC50 = 704 nM
|
|
|
|
CP0451642
|
3-[(Z)-2-Phenylvinyl]pyridine
Show/Hide
|
C13H11N
|
1
|
| 1 |
IC50 = 735 nM
|
|
|
|
CP0402839
|
2-[5-(3-cyclopropylindazol-1-yl)pyridin-3-yl]propan-2-ol
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0414315
|
1-(8-isoquinolin-4-yl-2,8-diazaspiro[4.5]decan-2-yl)ethanone
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 = 1031 nM
|
|
|
|
CP0414316
|
tert-butyl 8-isoquinolin-4-yl-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 = 1134 nM
|
|
|
|
CP0548132
|
1-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]indazole-5-carbonitrile
Show/Hide
|
C16H14N4O
|
1
|
| 1 |
IC50 = 1156 nM
|
|
|
|
CP0491364
|
1-cyclopropyl-2-pyridin-3-ylbenzimidazole-5-carbonitrile
Show/Hide
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C16H12N4
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1
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| 1 |
IC50 = 1768 nM
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CP0507037
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2-[5-[6-(trifluoromethyl)indazol-1-yl]pyridin-3-yl]propan-2-ol
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C16H14F3N3O
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1
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| 1 |
IC50 = 2300 nM
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CP0442678
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1-cyclohexyl-7-pyridin-3-yl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
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C21H22N4
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1
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| 1 |
IC50 = 2400 nM
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CP0419465
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4-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine
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C16H15NO
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1
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| 1 |
IC50 = 2834 nM
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CP0033431
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1-cyclopropyl-2-pyridin-3-yl-5-(trifluoromethyl)benzimidazole
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C16H12F3N3
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1
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| 1 |
IC50 > 10000 nM
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CP0388882
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6-fluoro-2-pyridin-3-yl-1H-benzimidazole
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C12H8FN3
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1
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| 1 |
IC50 > 10000 nM
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CP0408911
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8-isoquinolin-4-yl-2,8-diazaspiro[4.5]decane
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C17H21N3
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1
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| 1 |
IC50 > 10000 nM
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CP0457601
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1-cyclopropyl-5-methylsulfonyl-2-pyridin-3-ylbenzimidazole
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C16H15N3O2S
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1
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| 1 |
IC50 > 1000 nM
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CP0542683
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1-cyclopropyl-5-methoxy-2-pyridin-3-ylbenzimidazole
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C16H15N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0408854
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4-[5-[(dimethylamino)methyl]-1-methylpyrazol-4-yl]benzonitrile
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C14H16N4
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1
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| 1 |
IC50 > 1000 nM
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CP0446793
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2-[[(5R)-3-(4-cyano-2-methylphenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-5-yl]oxy]acetic acid
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C16H15N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0465188
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4-[5-(hydroxymethyl)-1-methylpyrazol-4-yl]benzonitrile
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C12H11N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0558628
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4-(1-methylpyrazol-4-yl)benzonitrile
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C11H9N3
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1
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| 1 |
IC50 > 1000 nM
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CP0388880
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1-cyclobutyl-6-fluoro-2-pyridin-3-ylbenzimidazole
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C16H14FN3
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1
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| 1 |
IC50 > 5000 nM
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CP0491363
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1-tert-butyl-6-fluoro-2-pyridin-3-ylbenzimidazole
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C16H16FN3
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1
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| 1 |
IC50 > 5000 nM
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CP0414311
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8-isoquinolin-4-yl-2-methyl-2,8-diazaspiro[4.5]decan-1-one
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C18H21N3O
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1
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| 1 |
IC50 > 8000 nM
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CP0447890
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N,N-dimethyl-5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridine-3-carboxamide
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C19H19N5O
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1
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| 1 |
IC50 > 8333 nM
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CP0456370
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1-methyl-7-(5-methylsulfonylpyridin-3-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline
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C17H16N4O2S
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1
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| 1 |
IC50 > 8333 nM
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CP0484358
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N-methyl-5-(1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)pyridine-3-carboxamide
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C18H17N5O
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1
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| 1 |
IC50 > 8333 nM
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