| Compound ID |
Compound Name |
Compound Formula |
|
CP0740877
|
5-bromo-6-({2-[(5-bromo-2,6-dioxopyrimidin-4(1H,3H)-yl)amino]ethyl}amino)pyrimidine-2,4(1H,3H)-dione dihydrochloride
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|
C10H12Br2Cl2N6O4
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0702159
|
5-bromo-6-hydrazinouracil hydrochloride
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|
C4H6BrClN4O2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0795559
|
5-bromo-6-[4-(5-bromo-2,6-dioxopyrimidin-4(1H,3H)-yl)piperazin-1-yl]pyrimidine-2,4(1H,3H)-dione dihydrochloride
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|
C12H14Br2Cl2N6O4
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0806767
|
5-bromo-6-(4-(2-hydroxyethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C11H17BrClN3O3
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0714625
|
5-bromo-6-(pyrrolidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C8H11BrClN3O2
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0807081
|
5-bromo-6-(3-(hydroxymethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C10H15BrClN3O3
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0716989
|
6-(azetidin-1-yl)-5-bromopyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C7H9BrClN3O2
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0825996
|
5-bromo-6-(2-(hydroxymethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C10H15BrClN3O3
|
1
|
| 1 |
IC50 = 7000 nM
|
|
|
|
CP0926784
|
5-chloro-6-(cyclopropylamino)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C7H9Cl2N3O2
|
1
|
| 1 |
IC50 = 7000 nM
|
|
|
|
CP0731283
|
5-bromo-6-(cyclopropylamino)uracil hydrochloride
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|
C7H9BrClN3O2
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0808434
|
5-bromo-6-morpholinopyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C8H11BrClN3O3
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0959117
|
5-chloro-6-[4-(5-chloro-2,6-dioxopyrimidin-4(1H,3H)-yl)piperazin-1-yl]pyrimidine-2,4(1H,3H)-dione dihydrochloride
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|
C12H14Cl4N6O4
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0697744
|
5-bromo-6-(4-(hydroxymethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C10H15BrClN3O3
|
1
|
| 1 |
IC50 = 7500 nM
|
|
|
|
CP0806766
|
5-chloro-6-(3-(2-hydroxyethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C11H17Cl2N3O3
|
1
|
| 1 |
IC50 = 7500 nM
|
|
|
|
CP0731710
|
6-(azetidin-1-yl)-5-chloropyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C7H9Cl2N3O2
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0795560
|
5-chloro-6-(2-(hydroxymethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C10H15Cl2N3O3
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0720362
|
5-bromo-6-(piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C9H13BrClN3O2
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0795549
|
5-chloro-6-morpholinopyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C8H11Cl2N3O3
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0731709
|
5-chloro-6-(3-(hydroxymethyl)piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C10H15Cl2N3O3
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0707885
|
5-chloro-6-(pyrrolidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C8H11Cl2N3O2
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
|
CP0723392
|
5-chloro-6-hydrazinouracil hydrochloride
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|
C4H6Cl2N4O2
|
1
|
| 1 |
IC50 = 10200 nM
|
|
|
|
CP0697742
|
6-amino-5-chlorouracil hydrochloride
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|
C4H5Cl2N3O2
|
1
|
| 1 |
IC50 = 11600 nM
|
|
|
|
CP0795561
|
5-chloro-6-(piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride
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|
C9H13Cl2N3O2
|
1
|
| 1 |
IC50 = 15700 nM
|
|
|
|
CP0092617
|
5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
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|
C9H11ClN4O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0524537
|
5-Substituted-6-chlorouracil, 7a
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|
C9H9ClN2O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0484412
|
5-Substituted-6-chlorouracil, 10e
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|
C8H5ClN2O2S
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0500932
|
5-Substituted-6-chlorouracil, 10a
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|
C10H7ClN2O2
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0845137
|
6-chloro-5-[(1E)-pent-1-en-1-yl]pyrimidine-2,4(1H,3H)-dione
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|
C9H11ClN2O2
|
1
|
| 1 |
Ki = 410 nM
|
|
|
|
CP0467174
|
5-Substituted-6-chlorouracil, 7b
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|
C10H11ClN2O2
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0879673
|
6-chloro-5-[(1E)-1-ethylprop-1-en-1-yl]pyrimidine-2,4(1H,3H)-dione
Show/Hide
|
C9H11ClN2O2
|
1
|
| 1 |
Ki = 490 nM
|
|
|
|
CP0489293
|
6-Fluoro-5-phenylpyrimidine-2,4(1H,3H)-dione, 21
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|
C10H7FN2O2
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0910674
|
5-[(1E)-but-1-en-1-yl]-6-chloropyrimidine-2,4(1H,3H)-dione
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|
C8H9ClN2O2
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0500931
|
5-Substituted-6-chlorouracil, 10d
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|
C10H6ClFN2O2
|
1
|
| 1 |
Ki = 710 nM
|
|
|
|
CP0373172
|
5-Substituted-6-chlorouracil, 5c
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|
C8H11ClN2O2
|
1
|
| 1 |
Ki = 1030 nM
|
|
|
|
CP0489315
|
5-Substituted-6-chlorouracil, 5f
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|
C11H17ClN2O2
|
1
|
| 1 |
Ki = 1060 nM
|
|
|
|
CP0906066
|
6-chloro-5-[(1E)-prop-1-en-1-yl]pyrimidine-2,4(1H,3H)-dione
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|
C7H7ClN2O2
|
1
|
| 1 |
Ki = 1170 nM
|
|
|
|
CP0490924
|
6-Bromo-5-phenylpyrimidine-2,4(1H,3H)-dione, 23
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|
C10H7BrN2O2
|
1
|
| 1 |
Ki = 1210 nM
|
|
|
|
CP0528114
|
5-Substituted-6-chlorouracil, 10b
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|
C12H11ClN2O2
|
1
|
| 1 |
Ki = 1740 nM
|
|
|
|
CP0477931
|
5-Substituted-6-chlorouracil, 5e
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|
C10H15ClN2O2
|
1
|
| 1 |
Ki = 1830 nM
|
|
|
|
CP0906067
|
6-chloro-5-pyridin-3-ylpyrimidine-2,4(1H,3H)-dione hydrochloride
Show/Hide
|
C9H7Cl2N3O2
|
1
|
| 1 |
Ki = 3010 nM
|
|
|
|
CP0405260
|
5-Substituted-6-chlorouracil, 7c
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|
C7H7ClN2O2
|
1
|
| 1 |
Ki = 3340 nM
|
|
|
|
CP0489295
|
5-Substituted-6-chlorouracil, 5d
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|
C9H13ClN2O2
|
1
|
| 1 |
Ki = 3670 nM
|
|
|
|
CP0438978
|
5-Substituted-6-chlorouracil, 10c
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|
C14H9ClN2O2
|
1
|
| 1 |
Ki = 4590 nM
|
|
|
|
CP0489314
|
5-Substituted-6-chlorouracil, 5g
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|
C11H9ClN2O2
|
1
|
| 1 |
Ki = 4650 nM
|
|
|
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CP0467173
|
5-Substituted-6-chlorouracil, 5b
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|
C7H9ClN2O2
|
1
|
| 1 |
Ki = 5810 nM
|
|
|
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CP0373170
|
5-Phenyl-6-pyrrolidin-1-ylpyrimidine-2,4(1H,3H)-dione, 24
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|
C14H15N3O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
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CP0477930
|
6-Methyl-5-phenylpyrimidine-2,4(1H,3H)-dione, 16
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|
C11H10N2O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0511118
|
5-Substituted-6-chlorouracil, 5a
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|
C6H7ClN2O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
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CP0528111
|
6-[(2-Aminoethyl)amino]-5-phenylpyrimidine-2,4(1H,3H)-dione, 25
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|
C12H14N4O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
