General Information of the Cell Line
Cell Line ID
CL000805
Cell Line Name
HBE1
Synonyms
HBE-1
Human Bronchial Epithelial cell Line 1
Category
Transformed cell line
Organism
Homo sapiens (Human)
Tissue Information
Lung
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02042, ATP-binding cassette sub-family C member 7
 Protein Info 
Compound ID Compound Name Compound Formula
CP0579435
 Compound Info 
2-[6-(difluoromethyl)pyridin-2-yl]-1-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
   Show/Hide
C28H25F2N3O4S
  1
1
EC50 = 0.4 nM
 Bioactivity Info 
   TI
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CP0571389
 Compound Info 
1-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonyl-2-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboxamide
   Show/Hide
C29H25F3N2O4S
  1
1
EC50 = 0.51 nM
 Bioactivity Info 
   TI
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CP0575716
 Compound Info 
1-(2-methoxy-5-methylphenyl)-2-(4-methoxyphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
   Show/Hide
C29H28N2O5S
  1
1
EC50 = 0.66 nM
 Bioactivity Info 
   TI
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CP0571732
 Compound Info 
1-(2-methoxy-5-methylphenyl)-2-(4-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
   Show/Hide
C29H28N2O4S
  1
1
EC50 = 0.8 nM
 Bioactivity Info 
   TI
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CP0571138
 Compound Info 
1-(2-methoxy-5-methylphenyl)-2-(3-methoxyphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
   Show/Hide
C29H28N2O5S
  1
1
EC50 = 0.84 nM
 Bioactivity Info 
   TI
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CP0578716
 Compound Info 
1-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonyl-2-(6-propan-2-yloxypyridin-2-yl)cyclopropane-1-carboxamide
   Show/Hide
C30H31N3O5S
  1
1
EC50 = 0.9 nM
 Bioactivity Info 
   TI
   LI
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CP0388845
 Compound Info 
N-(4-tert-butyl-3-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
   Show/Hide
C20H20N2O3
  1
1
EC50 = 5 nM
 Bioactivity Info 
   TI
   LI
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CP0362762
 Compound Info 
3-amino-N-[(2S)-2-hydroxypropyl]-5-[4-(trifluoromethoxy)phenyl]sulfonylpyridine-2-carboxamide
   Show/Hide
C16H16F3N3O5S
  1
1
EC50 = 18 nM
 Bioactivity Info 
   TI
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CP0088272
 Compound Info 
CHEBI:66901
   Show/Hide
C24H28N2O3
  4
1
EC50 = 22 nM
 Bioactivity Info 
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2
EC50 = 34 nM
 Bioactivity Info 
   TI
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3
EC50 = 68 nM
 Bioactivity Info 
   TI
   LI
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4
EC50 = 236 nM
 Bioactivity Info 
   TI
   LI
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CP0490597
 Compound Info 
N-[4-tert-butyl-5-hydroxy-2-(trifluoromethyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide
   Show/Hide
C21H19F3N2O3
  1
1
EC50 = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0494908
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-(2-methylanilino)-1-[(2S)-oxane-2-carbonyl]-5-(2-propan-2-ylphenyl)pyrrolidine-2-carboxylic acid
   Show/Hide
C31H42N2O4
  1
1
EC50 = 22 nM
 Bioactivity Info 
   TI
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CP0532736
 Compound Info 
3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3,3-trifluoro-2-hydroxy-2-methyl-propyl)-amide
   Show/Hide
C11H10BrF6N3O2
  1
1
EC50 = 25 nM
 Bioactivity Info 
   TI
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CP0551217
 Compound Info 
US10117858, Example 5
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C12H13F6N3O3
  2
1
EC50 = 39 nM
 Bioactivity Info 
   TI
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2
EC50 = 72 nM
 Bioactivity Info 
   TI
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CP0527765
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-5-[(5-cyclobutyl-2-methoxypyridin-3-yl)methyl]-4-[(5-cyclobutyl-2-methoxypyridin-3-yl)methylamino]-1-[(2S)-oxane-2-carbonyl]pyrrolidine-2-carboxylic acid
   Show/Hide
C37H52N4O6
  1
1
EC50 = 41 nM
 Bioactivity Info 
   TI
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CP0387052
 Compound Info 
N-(3-tert-butyl-1H-indol-6-yl)-4-oxo-1H-quinoline-3-carboxamide
   Show/Hide
C22H21N3O2
  1
1
EC50 = 42 nM
 Bioactivity Info 
   TI
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CP0400231
 Compound Info 
N-(4-tert-butyl-2-fluoro-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
   Show/Hide
C20H19FN2O3
  1
1
EC50 = 45 nM
 Bioactivity Info 
   TI
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CP0494401
 Compound Info 
N-(5-tert-butyl-1H-indol-6-yl)-4-oxo-1H-quinoline-3-carboxamide
   Show/Hide
C22H21N3O2
  1
1
EC50 = 97 nM
 Bioactivity Info 
   TI
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CP0532463
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxypyridin-3-yl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C33H47N3O4
  1
1
EC50 = 107 nM
 Bioactivity Info 
   TI
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CP0562768
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C34H48N2O4
  1
1
EC50 = 113 nM
 Bioactivity Info 
   TI
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CP0527833
 Compound Info 
(2S,3S,4S,5S)-4-[[5-(1-adamantyl)-2-methoxyphenyl]methylamino]-3-tert-butyl-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C40H54N2O4
  1
1
EC50 = 136 nM
 Bioactivity Info 
   TI
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CP0353054
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[[2-(dimethylamino)pyridin-3-yl]amino]-1-[(2S)-oxane-2-carbonyl]-5-(2-propan-2-ylphenyl)pyrrolidine-2-carboxylic acid
   Show/Hide
C31H44N4O4
  1
1
EC50 = 142 nM
 Bioactivity Info 
   TI
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CP0569896
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-5-[[2-methoxy-5-(trifluoromethyl)pyridin-3-yl]methyl]-1-[(2S)-oxane-2-carbonyl]pyrrolidine-2-carboxylic acid
   Show/Hide
C35H48F3N3O6
  1
1
EC50 = 159 nM
 Bioactivity Info 
   TI
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CP0576906
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-cyclobutyl-2-methoxypyridin-3-yl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C33H45N3O4
  1
1
EC50 = 184 nM
 Bioactivity Info 
   TI
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CP0532464
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-1-(cyclohexanecarbonyl)-4-[(2-methoxy-5-propan-2-ylphenyl)methylamino]-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C33H46N2O4
  1
1
EC50 = 188 nM
 Bioactivity Info 
   TI
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CP0575054
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-1-(cyclohexanecarbonyl)-4-[[2-methoxy-5-(3-tricyclo[3.1.0.01,3]hexanyl)phenyl]methylamino]-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C36H46N2O4
  1
1
EC50 = 190 nM
 Bioactivity Info 
   TI
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CP0527764
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-1-(cyclohexanecarbonyl)-4-[[2-methoxy-5-(trifluoromethyl)pyridin-3-yl]methylamino]-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C30H38F3N3O4
  1
1
EC50 = 210 nM
 Bioactivity Info 
   TI
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CP0543195
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-chloro-2-methoxyphenyl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C30H39ClN2O4
  1
1
EC50 = 241 nM
 Bioactivity Info 
   TI
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CP0575055
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-1-[(2S)-oxane-2-carbonyl]-5-phenylpyrrolidine-2-carboxylic acid
   Show/Hide
C33H46N2O5
  1
1
EC50 = 321 nM
 Bioactivity Info 
   TI
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CP0550164
 Compound Info 
(6R,12R)-17-amino-12-(hydroxymethyl)-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
   Show/Hide
C17H18F6N4O4
  1
1
EC50 < 500 nM
 Bioactivity Info 
   TI
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CP0550165
 Compound Info 
(6R,12R)-17-amino-8,9-dideuterio-12-methyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
   Show/Hide
C17H18F6N4O3
  1
1
EC50 < 500 nM
 Bioactivity Info 
   TI
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CP0550166
 Compound Info 
(6R)-17-amino-11,11-dimethyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
   Show/Hide
C18H20F6N4O3
  1
1
EC50 < 500 nM
 Bioactivity Info 
   TI
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CP0577539
 Compound Info 
(6R,12S)-17-amino-12-methyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
   Show/Hide
C17H18F6N4O3
  1
1
EC50 < 500 nM
 Bioactivity Info 
   TI
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CP0579031
 Compound Info 
17-amino-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
   Show/Hide
C16H16F6N4O3
  1
1
EC50 < 500 nM
 Bioactivity Info 
   TI
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CP0579780
 Compound Info 
(6R)-17-amino-6,15-bis(trifluoromethyl)-19-oxa-13-thia-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
   Show/Hide
C16H16F6N4O2S
  1
1
EC50 < 500 nM
 Bioactivity Info 
   TI
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CP0385469
 Compound Info 
7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7-dihydro-5H-5,7,9,11a-tetraaza-benzo[a]fluorene-8,10-dione
   Show/Hide
C26H22N4O3
  1
1
IC50 < 1000 nM
 Bioactivity Info 
   TI
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lung)
Cell Line Name Organism Disease
T84
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
CFBE41o-
 Cell Line Info 
Homo sapiens (Human) Cystic fibrosis
A-549
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1975
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2073
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC827
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2228
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
A-427
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC44
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC1171
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
MR-5
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H522
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC366
 Cell Line Info 
Homo sapiens (Human) Lung adenosquamous carcinoma
NCI-H1581
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
DMS 53
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H1417
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
SW900
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H520
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1703
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H2286
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
Malme-3M
 Cell Line Info 
Homo sapiens (Human) Melanoma
NCI-H358
 Cell Line Info 
Homo sapiens (Human) Minimally invasive lung adenocarcinoma
LLTC
 Cell Line Info 
Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
LLTC
 Cell Line Info 
Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
T8
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant mesothelioma
V79MZ
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
V79
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
V79MZh11B2
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
V79MZh11B1
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
Dede
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
39ER22
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
PS120
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
CHL
 Cell Line Info 
Cricetulus griseus (Chinese hamster) -
NP1
 Cell Line Info 
Homo sapiens (Human) -
IMR-90
 Cell Line Info 
Homo sapiens (Human) -
Hs 888.Lu
 Cell Line Info 
Homo sapiens (Human) -
BEAS-2B
 Cell Line Info 
Homo sapiens (Human) -
WI-38
 Cell Line Info 
Homo sapiens (Human) -
HL
 Cell Line Info 
Homo sapiens (Human) -
HFL1
 Cell Line Info 
Homo sapiens (Human) -
WI-38 VA13 subline 2RA
 Cell Line Info 
Homo sapiens (Human) -
16HBE14o-
 Cell Line Info 
Homo sapiens (Human) -
NAL1A clone C4E10
 Cell Line Info 
Mus musculus (Mouse) -
Mv1Lu
 Cell Line Info 
Neovison vison (American mink) -
RFL-6
 Cell Line Info 
Rattus norvegicus (Rat) -
PAC1
 Cell Line Info 
Rattus norvegicus (Rat) -
RLE
 Cell Line Info 
Rattus norvegicus (Rat) -