Brief Information of the Compound and Protein
Compound Name
N-(5-tert-butyl-1H-indol-6-yl)-4-oxo-1H-quinoline-3-carboxamide
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PubChem ID
CID: 66675121
Canonical SMILES
CC(C)(C)c1cc2cc[nH]c2cc1NC(=O)c1c[nH]c2ccccc2c1=O
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Compound Formula C22H21N3O2
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000805 HBE1 Homo sapiens (Human)  1
1
EC50 = 97 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS