Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6R,12R)-17-amino-8,9-dideuterio-12-methyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
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 PubChem ID
CID: 162772609
Canonical SMILES
[2H]C1CC[C@@H](C)Oc2nc(-c3nnc(o3)[C@](O)(CC1[2H])C(F)(F)F)c(N)cc2C(F)(F)F
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Compound Formula C17H18F6N4O3
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000805 HBE1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 < 500 nM
   TI
   LI
   LO
   TS