Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-5-[[2-methoxy-5-(trifluoromethyl)pyridin-3-yl]methyl]-1-[(2S)-oxane-2-carbonyl]pyrrolidine-2-carboxylic acid
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 PubChem ID
CID: 168274307
Canonical SMILES
COc1ccc(cc1CN[C@@H]1[C@H](Cc2cc(cnc2OC)C(F)(F)F)N([C@@H]([C@H]1C(C)(C)C)C(O)=O)C(=O)[C@@H]1CCCCO1)C(C)(C)C
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Compound Formula C35H48F3N3O6
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000805 HBE1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 159 nM
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