Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-tert-butyl-1H-indol-6-yl)-4-oxo-1H-quinoline-3-carboxamide
    Show/Hide
 PubChem ID
CID: 66675750
Canonical SMILES
CC(C)(C)c1c[nH]c2cc(NC(=O)c3c[nH]c4ccccc4c3=O)ccc12
    Show/Hide
Compound Formula C22H21N3O2
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000805 HBE1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 42 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS