General Information of the Cell Line
Cell Line ID
CL000979
Cell Line Name
LLTC
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Tissue Information
Lung
Disease
Malignant tumors of the mouse pulmonary system (NCIt: C21769)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01557, Indoleamine 2,3-dioxygenase 1
Compound ID Compound Name Compound Formula
CP0236732
4-amino-N-(3-chloro-4-fluorophenyl)-N&#8242;-hydroxy-1,2,5-oxadiazole-3-carboximidamide
   Show/Hide
C9H7ClFN5O2
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0094769
6-[(2,4-dichlorophenyl)methylsulfanyl]-1H-pyrimidin-2-one
   Show/Hide
C11H8Cl2N2OS
 2
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
2
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0102032
1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol
   Show/Hide
C18H22N2O
 1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CP0067225
1-oxidanidyl-2-phenyl-indol-1-ium-3-one
   Show/Hide
C14H9NO2
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0403366
2-(4-methoxyphenyl)-1-oxidoindol-1-ium-3-one
   Show/Hide
C15H11NO3
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0386844
2-(2-methylphenyl)-1-oxidoindol-1-ium-3-one
   Show/Hide
C15H11NO2
 1
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0513573
5,6-dimethoxy-1-oxido-2-phenylindol-1-ium-3-one
   Show/Hide
C16H13NO4
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0393100
4-(4-methylphenyl)sulfanyl-7-nitro-2,1,3-benzoxadiazole
   Show/Hide
C13H9N3O3S
 1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0572901
4-(4-fluorophenyl)sulfanyl-7-nitro-2,1,3-benzoxadiazole
   Show/Hide
C12H6FN3O3S
 1
1
IC50 = 4600 nM
   TI
   LI
   LO
   TS
CP0307916
2-chloro-N-[(4-chlorophenyl)sulfanylmethyl]aniline
   Show/Hide
C13H11Cl2NS
 1
1
IC50 = 6300 nM
   TI
   LI
   LO
   TS
CP0393678
N-[(4-chlorophenyl)sulfanylmethyl]-2-nitroaniline
   Show/Hide
C13H11ClN2O2S
 1
1
IC50 = 6300 nM
   TI
   LI
   LO
   TS
CP0571824
S-(2-chlorophenyl) N-(4-chlorophenyl)carbamothioate
   Show/Hide
C13H9Cl2NOS
 1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0309909
4-Chloro-benzenethiol
   Show/Hide
C6H5ClS
 1
1
IC50 = 9200 nM
   TI
   LI
   LO
   TS
CP0267697
4-(4-methylphenyl)sulfinyl-7-nitro-2,1,3-benzoxadiazole
   Show/Hide
C13H9N3O4S
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0475154
4-[(2,4-dichlorophenyl)methylsulfanyl]-6-methyl-5,6-dihydro-1H-pyrimidin-2-one
   Show/Hide
C12H12Cl2N2OS
 1
1
IC50 = 44000 nM
   TI
   LI
   LO
   TS
CP0232874
6-(1,3-dihydrophenanthr[9,10-d]imidazol-2-ylidene)cyclohexa-2,4-dien-1-one
   Show/Hide
C21H14N2O
 1
1
IC50 = 52000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0067225
1-oxidanidyl-2-phenyl-indol-1-ium-3-one
   Show/Hide
C14H9NO2  1
1
LC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0094769
6-[(2,4-dichlorophenyl)methylsulfanyl]-1H-pyrimidin-2-one
   Show/Hide
C11H8Cl2N2OS  1
1
LC50 > 117000 nM
   TI
   LI
   LO
   TS
CP0393678
N-[(4-chlorophenyl)sulfanylmethyl]-2-nitroaniline
   Show/Hide
C13H11ClN2O2S  1
1
LC50 = 52000 nM
   TI
   LI
   LO
   TS
CP0403366
2-(4-methoxyphenyl)-1-oxidoindol-1-ium-3-one
   Show/Hide
C15H11NO3  1
1
LC50 = 42000 nM
   TI
   LI
   LO
   TS
CP0572901
4-(4-fluorophenyl)sulfanyl-7-nitro-2,1,3-benzoxadiazole
   Show/Hide
C12H6FN3O3S  1
1
LC50 > 50000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lung)
Cell Line Name Organism Disease
T84 Homo sapiens (Human) Colon adenocarcinoma
CFBE41o- Homo sapiens (Human) Cystic fibrosis
A-549 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1975 Homo sapiens (Human) Lung adenocarcinoma
NCI-H2073 Homo sapiens (Human) Lung adenocarcinoma
HCC827 Homo sapiens (Human) Lung adenocarcinoma
NCI-H2228 Homo sapiens (Human) Lung adenocarcinoma
A-427 Homo sapiens (Human) Lung adenocarcinoma
HCC44 Homo sapiens (Human) Lung adenocarcinoma
HCC1171 Homo sapiens (Human) Lung adenocarcinoma
MR-5 Homo sapiens (Human) Lung adenocarcinoma
NCI-H522 Homo sapiens (Human) Lung adenocarcinoma
HCC366 Homo sapiens (Human) Lung adenosquamous carcinoma
NCI-H1581 Homo sapiens (Human) Lung large cell carcinoma
DMS 53 Homo sapiens (Human) Lung small cell carcinoma
NCI-H1417 Homo sapiens (Human) Lung small cell carcinoma
SW900 Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H520 Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1703 Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H2286 Homo sapiens (Human) Lung squamous cell carcinoma
Malme-3M Homo sapiens (Human) Melanoma
NCI-H358 Homo sapiens (Human) Minimally invasive lung adenocarcinoma
LLTC Mus musculus (Mouse) Malignant tumors of the mouse pulmonary system
T8 Rattus norvegicus (Rat) Rat malignant mesothelioma
V79MZ Cricetulus griseus (Chinese hamster) -
V79 Cricetulus griseus (Chinese hamster) -
V79MZh11B2 Cricetulus griseus (Chinese hamster) -
V79MZh11B1 Cricetulus griseus (Chinese hamster) -
Dede Cricetulus griseus (Chinese hamster) -
39ER22 Cricetulus griseus (Chinese hamster) -
PS120 Cricetulus griseus (Chinese hamster) -
CHL Cricetulus griseus (Chinese hamster) -
NP1 Homo sapiens (Human) -
IMR-90 Homo sapiens (Human) -
Hs 888.Lu Homo sapiens (Human) -
BEAS-2B Homo sapiens (Human) -
WI-38 Homo sapiens (Human) -
HL Homo sapiens (Human) -
HFL1 Homo sapiens (Human) -
WI-38 VA13 subline 2RA Homo sapiens (Human) -
HBE1 Homo sapiens (Human) -
16HBE14o- Homo sapiens (Human) -
NAL1A clone C4E10 Mus musculus (Mouse) -
Mv1Lu Neovison vison (American mink) -
RFL-6 Rattus norvegicus (Rat) -
PAC1 Rattus norvegicus (Rat) -
RLE Rattus norvegicus (Rat) -