Brief Information of the Compound and Protein
Compound Name
1-(2-methoxy-5-methylphenyl)-2-(3-methoxyphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
    Show/Hide
PubChem ID
CID: 168279290
Canonical SMILES
COc1cccc(c1)C1CC1(C(=O)NS(=O)(=O)c1cccc2nc(C)ccc12)c1cc(C)ccc1OC
    Show/Hide
Compound Formula C29H28N2O5S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000805 HBE1 Homo sapiens (Human)  1
1
EC50 = 0.84 nM
   TI
   LI
   LO
   TS