Brief Information of the Compound and Protein
Compound Name
4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-(3-thienyl)azepan-3-yl]piperidine-1-carboxamide
    Show/Hide
PubChem ID
CID: 23656749
SID: 46529082
Canonical SMILES
O=C(N[C@@H]1CCC(CNC1=O)c1ccsc1)N1CCC(CC1)n1c2cccnc2[nH]c1=O
    Show/Hide
Compound Formula C22H26N6O3S
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Calcitonin-like receptor
>
Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 470 nM
   TI
   LI
   LO
   TS
CL000748 NAL1A clone C4E10 Mus musculus (Mouse)  2
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
2
IC50 = 1800 nM
   TI
   LI
   LO
   TS