Brief Information of the Cell Line and Protein
Cell Line ID: CL000192 , AD-293
Synonyms
Ad-293
AD293
Adeno-293
Adeno 293
HEK-AD293
HEK (AD293)
HEK AD293
HEK-AD 293
AdHek
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_9804
Protein ID: PT03374 , Estrogen-related receptor gamma
Gene Name ESRRG
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P62508
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000192  Protein ID: PT03374
 
Compound ID Compound Name Compound Formula
CP0164237
4-[(E)-5-hydroxy-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol;dihydrochloride
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C30H38Cl2N2O2
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0096836
(Z)-5-[4-(4-ethylpiperazin-1-yl)phenyl]-5-(4-methylphenyl)-4-phenylpent-4-en-1-ol;dihydrochloride
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C30H38Cl2N2O
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0117254
(Z)-5-(4-methylphenyl)-4-phenyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-4-en-1-ol;dihydrochloride
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C31H40Cl2N2O
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0344043
(E)-5-(3-bromophenyl)-4-phenyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-4-en-1-ol;dihydrochloride
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C30H37BrCl2N2O
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0143014
3-[(E)-5-hydroxy-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol;dihydrochloride
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C30H38Cl2N2O2
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0131412
4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-5-fluoro-2-phenylpent-1-enyl]phenol;hydrochloride
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C27H31ClFNO2
 1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
CP0133940
4-[(Z)-1-[4-[3-(dimethylamino)propoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenol;hydrochloride
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C28H34ClNO3
 1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
CP0536297
(E)-5-(4-bromophenyl)-4-phenyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-4-en-1-ol;dihydrochloride
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C30H37BrCl2N2O
 1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CP0060960
(Z)-5-(4-methylphenyl)-4-phenyl-5-(4-piperazin-1-ylphenyl)pent-4-en-1-ol;dihydrochloride
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C28H34Cl2N2O
 1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS
CP0060959
(Z)-5-(4-methylphenyl)-5-[4-(4-methylpiperazin-1-yl)phenyl]-4-phenylpent-4-en-1-ol;dihydrochloride
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C29H36Cl2N2O
 1
1
IC50 = 69 nM
   TI
   LI
   LO
   TS
CP0739308
4-[(Z)-1-[4-(2-dimethylaminoethyloxy)phenyl]-5-hydroxy-2-phenyl-pent-1-enyl]phenol hydrochloride salt
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C27H32ClNO3
 1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
CP0132048
4-[(Z)-1-[4-[2-(diethylamino)ethoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenol;hydrochloride
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C29H36ClNO3
 1
1
IC50 = 79 nM
   TI
   LI
   LO
   TS
CP0197679
4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-5,5-difluoro-2-phenylpent-1-enyl]phenol;hydrochloride
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C27H30ClF2NO2
 1
1
IC50 = 111 nM
   TI
   LI
   LO
   TS
CP0316921
4-[(Z)-5-hydroxy-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylpent-1-enyl]phenol;hydrochloride
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C26H30ClNO3
 1
1
IC50 = 187 nM
   TI
   LI
   LO
   TS
CP0182080
(Z)-5-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-methylphenyl)-4-phenylpent-4-en-1-ol;hydrochloride
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C28H34ClNO2
 1
1
IC50 = 669 nM
   TI
   LI
   LO
   TS
CP0182081
(E)-5-(4-bromophenyl)-5-[4-[2-(dimethylamino)ethoxy]phenyl]-4-phenylpent-4-en-1-ol;hydrochloride
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C27H31BrClNO2
 1
1
IC50 = 719 nM
   TI
   LI
   LO
   TS