Brief Information of the Cell Line and Protein
Cell Line ID: CL000036 , MDCK-II
Synonyms
MDCK II
MDCKII
MDCK2
MDCK-2
MDCK Type II
MDCKII-WT
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_0424
Protein ID: PT05367 , Multidrug and toxin extrusion protein 1
Gene Name SLC47A1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q96FL8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000036  Protein ID: PT05367
 
Compound ID Compound Name Compound Formula
CP0000082
CAS_68647
   Show/Hide
C18H19N3O
 1
1
IC50 < 10 nM
   TI
   LI
   LO
   TS
CP0002778
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
C29H31N7O
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0002490
1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis(oxidanyl)anthracene-9,10-dione;hydrochloride
   Show/Hide
C22H28N4O6
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0014442
4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydroxyethanesulfonic acid
   Show/Hide
C19H24N4O2
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0052856
6-(2-{(2-Hydroxy-ethyl)-[3-(4-nitro-phenyl)-propyl]-amino}-ethylamino)-1,3-dimethyl-1H-pyrimidine-2,4-dione
   Show/Hide
C19H27N5O5
 1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0040838
(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide
   Show/Hide
C36H47N5O4
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0036175
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
   Show/Hide
C37H48N6O5S2
 1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CP0050753
5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole
   Show/Hide
C16H15F2N3O4S
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0076378
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
   Show/Hide
C33H38N4O6
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS