Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Dimethyl-{8-[5-(piperidine-1-carbothioyl)-thiophen-2-yl]-2,3,5,6-tetrahydro-1H,4H-13-thia-3a-aza-benzo[de]naphthacen-11-ylidene}-ammonium hexafluoro phosphate
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 PubChem ID
CID: 42647274
SID: 81086963
Canonical SMILES
C[N+](C)=c1ccc2c(-c3ccc(C(=S)N4CCCCC4)s3)c3cc4c5c(c3sc-2c1)CCCN5CCC4.F[P-](F)(F)(F)(F)F
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Compound Formula C31H34F6N3PS3
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  3
1
IC50 = 670 nM
   TI
   LI
   LO
   TS
2
Km = 87 nM
   TI
   LI
   LO
   TS
3
Km = 2500 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CL000036 MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog)  2
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
2
IC50 = 12000 nM
   TI
   LI
   LO
   TS