General Information of the Cell Line
Cell Line ID
CL000588
Cell Line Name
SiHa
Synonyms
Siha
SIHA
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0032
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT04442, D-3-phosphoglycerate dehydrogenase
Compound ID Compound Name Compound Formula
CP0187002
(3,4-DICHLOROPHENYL)(MORPHOLINO)METHANETHIONE
   Show/Hide
C11H11Cl2NOS
 2
1
IC50 = 5600 nM
   TI
   LI
   LO
   TS
2
IC50 = 19100 nM
   TI
   LI
   LO
   TS
CP0481473
1-(4-chlorophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone
   Show/Hide
C12H12ClNO2S
 2
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS
2
IC50 = 21000 nM
   TI
   LI
   LO
   TS
CP0413318
2-morpholin-4-yl-1-(4-nitrophenyl)-2-sulfanylideneethanone
   Show/Hide
C12H12N2O4S
 2
1
IC50 = 7600 nM
   TI
   LI
   LO
   TS
2
IC50 = 22800 nM
   TI
   LI
   LO
   TS
CP0273261
2-morpholin-4-yl-1-phenyl-2-sulfanylideneethanone
   Show/Hide
C12H13NO2S
 2
1
IC50 = 7900 nM
   TI
   LI
   LO
   TS
2
IC50 = 71700 nM
   TI
   LI
   LO
   TS
CP0413322
1-(4-bromophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone
   Show/Hide
C12H12BrNO2S
 2
1
IC50 = 7900 nM
   TI
   LI
   LO
   TS
2
IC50 = 20400 nM
   TI
   LI
   LO
   TS
CP0483582
1-(4-iodophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone
   Show/Hide
C12H12INO2S
 2
1
IC50 = 9300 nM
   TI
   LI
   LO
   TS
2
IC50 = 25700 nM
   TI
   LI
   LO
   TS
CP0483581
1-(4-fluorophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone
   Show/Hide
C12H12FNO2S
 2
1
IC50 = 43300 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0492769
4-chloro-N-(2-nitrophenyl)benzamide
   Show/Hide
C13H9ClN2O3
 2
1
IC50 = 57500 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0413319
1-(3-chlorophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone
   Show/Hide
C12H12ClNO2S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0483584
1-(2-chlorophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone
   Show/Hide
C12H12ClNO2S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0435114
2-oxo-7-pyrrolidin-1-ylchromene-3-carboxylic acid
   Show/Hide
C14H13NO4  1
1
EC50 = 14300 nM
   TI
   LI
   LO
   TS
CP0475758
7-methoxy-2-oxochromene-3-carboxylic acid
   Show/Hide
C11H8O5  1
1
EC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0490049
1-ethyl-2-oxo-7-phenylmethoxyquinoline-3-carboxylic acid
   Show/Hide
C19H17NO4  1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0928203
(2S,3S,4S)-2-((1R)-2-Amino-1-((2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-oxoethoxy)-3,4-dihydroxy-N-(4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)benzyl)-3,4-dihydro-2H-pyran-6-carboxamide
   Show/Hide
C36H40F3N5O13  1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+ Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4 Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2 Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5 Homo sapiens (Human) Uterine corpus sarcoma
MES-SA Homo sapiens (Human) Uterine corpus sarcoma